Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein-mediated neurodegeneration

Human Molecular Genetics

Volumn 24, Issue 8, 2015, Pages 2228-2240

  Wiesner, Diana ^a   Sinniger, Jérome ^c,d   Henriques, Alexandre ^c,d   Dieterlé, Stéphane ^c,d   Müller, Hans Peter ^a   Rasche, Volker ^a   Ferger, Boris ^e   Dirrig Grosch, Sylvie ^c,d   Soylu Kucharz, Rana ^f   Petersén, Asa ^f   Walther, Paul ^b   Linkus, Birgit ^a   Kassubek, Jan ^a   Wong, Philip C ^g   Ludolph, Albert C ^a   Dupuis, Luc ^c,d  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b UNIVERSITY OF ULM   (Germany)

^c Laboratoire des Mecanismes Centraux et Peripheriques de la Neurodegenerescence   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

^e BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^f LUND UNIVERSITY   (Sweden)

^g JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CATHEPSIN D; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; DCTN1 PROTEIN, HUMAN; DCTN1 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN INTAKE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BRAIN ATROPHY; CALORIC RESTRICTION; CHAPERONE-MEDIATED AUTOPHAGY; CONTROLLED STUDY; DIET THERAPY; DOPAMINERGIC NERVE CELL; ELECTROMYOGRAPHY; GENE MUTATION; GRIP STRENGTH; HEAVY CHAIN; IMMUNOHISTOCHEMISTRY; LYSOSOME; MACROAUTOPHAGY; MOTONEURON; MOTOR COORDINATION; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; MOUSE; MUSCLE STRENGTH; NERVE DEGENERATION; NERVE FIBER TRANSPORT; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN INTAKE; PROTEIN RESTRICTION; ROTAROD TEST; SYNAPSE VESICLE; TRANSCRIPTION REGULATION; WEIGHT REDUCTION; ANIMAL; C3H MOUSE; DISEASE MODEL; FEMALE; GENETICS; HUMAN; MALE; METABOLISM; MISSENSE MUTATION; MOTOR ACTIVITY; PATHOPHYSIOLOGY;

MUS;

ANIMALS; AUTOPHAGY; DIETARY PROTEINS; DISEASE MODELS, ANIMAL; DYNACTIN COMPLEX; DYNEINS; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C3H; MICROTUBULE-ASSOCIATED PROTEINS; MOTOR ACTIVITY; MOTOR NEURONS; MUTATION, MISSENSE; NERVE DEGENERATION;

EID: 84926435663     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu741     Document Type: Article

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