메뉴 건너뛰기




Volumn 166, Issue 3, 2015, Pages 153-161

Mechanisms of azole resistance in Candida albicans clinical isolates from Shanghai, China

Author keywords

Biosynthetic pathway; Efflux pumps; ERG11; Ergosterol; Transcription factor; Triazole resistance

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; ERGOSTEROL; FLUCONAZOLE; FLUCYTOSINE; ITRACONAZOLE; MULTIDRUG RESISTANCE PROTEIN 1; RHODAMINE 6G; TRANSCRIPTION FACTOR; TRIAZOLE DERIVATIVE; VORICONAZOLE; LANOSTEROL; PYRROLE DERIVATIVE;

EID: 84926407087     PISSN: 09232508     EISSN: 17697123     Source Type: Journal    
DOI: 10.1016/j.resmic.2015.02.009     Document Type: Article
Times cited : (47)

References (29)
  • 1
    • 79955716397 scopus 로고    scopus 로고
    • Candida albicans, a major human fungal pathogen
    • Kim J., Sudbery P. Candida albicans, a major human fungal pathogen. J Microbiol 2011, 49:171-177.
    • (2011) J Microbiol , vol.49 , pp. 171-177
    • Kim, J.1    Sudbery, P.2
  • 2
    • 33846466508 scopus 로고    scopus 로고
    • Epidemiology of invasive candidiasis: a persistent public health problem
    • Pfaller M.A., Diekema D.J. Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev 2007, 20:133-163.
    • (2007) Clin Microbiol Rev , vol.20 , pp. 133-163
    • Pfaller, M.A.1    Diekema, D.J.2
  • 3
    • 78650924029 scopus 로고    scopus 로고
    • Geographic variations in species distribution and echinocandin and azole antifungal resistance rates among Candida bloodstream infection isolates: report from the SENTRY Antimicrobial Surveillance Program (2008 to 2009)
    • Pfaller M.A., Moet G.J., Messer S.A., Jones R.N., Castanheira M. Geographic variations in species distribution and echinocandin and azole antifungal resistance rates among Candida bloodstream infection isolates: report from the SENTRY Antimicrobial Surveillance Program (2008 to 2009). J Clin Microbiol 2011, 49:396-399.
    • (2011) J Clin Microbiol , vol.49 , pp. 396-399
    • Pfaller, M.A.1    Moet, G.J.2    Messer, S.A.3    Jones, R.N.4    Castanheira, M.5
  • 4
    • 84879480870 scopus 로고    scopus 로고
    • Invasive candidiasis in intensive care units in China: a multicentre prospective observational study
    • Guo F., Yang Y., Kang Y., Zang B., Cui W., Qin B., et al. Invasive candidiasis in intensive care units in China: a multicentre prospective observational study. J Antimicrob Chemother 2013, 68:1660-1668.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 1660-1668
    • Guo, F.1    Yang, Y.2    Kang, Y.3    Zang, B.4    Cui, W.5    Qin, B.6
  • 5
    • 84891557140 scopus 로고    scopus 로고
    • Invasive Candidiasis in preterm neonates in China: a retrospective study from 11 NICUS during 2009-2011
    • Xia H., Wu H., Xia S., Zhu X., Chen C., Qiu G., et al. Invasive Candidiasis in preterm neonates in China: a retrospective study from 11 NICUS during 2009-2011. Pediatr Infect Dis J 2014, 33:106-109.
    • (2014) Pediatr Infect Dis J , vol.33 , pp. 106-109
    • Xia, H.1    Wu, H.2    Xia, S.3    Zhu, X.4    Chen, C.5    Qiu, G.6
  • 6
    • 84890349673 scopus 로고    scopus 로고
    • Invasive candidiasis in intensive care units in China: invitro antifungal susceptibility in the China-SCAN study
    • Liu W., Tan J., Sun J., Xu Z., Li M., Yang Q., et al. Invasive candidiasis in intensive care units in China: invitro antifungal susceptibility in the China-SCAN study. J Antimicrob Chemother 2014, 69:162-167.
    • (2014) J Antimicrob Chemother , vol.69 , pp. 162-167
    • Liu, W.1    Tan, J.2    Sun, J.3    Xu, Z.4    Li, M.5    Yang, Q.6
  • 7
    • 84901497295 scopus 로고    scopus 로고
    • Epidemiology, species distribution and outcome of nosocomial Candida spp. bloodstream infection in Shanghai
    • Yang Z.T., Wu L., Liu X.Y., Zhou M., Li J., Wu J.Y., et al. Epidemiology, species distribution and outcome of nosocomial Candida spp. bloodstream infection in Shanghai. BMC Infect Dis 2014, 14:241.
    • (2014) BMC Infect Dis , vol.14 , pp. 241
    • Yang, Z.T.1    Wu, L.2    Liu, X.Y.3    Zhou, M.4    Li, J.5    Wu, J.Y.6
  • 8
    • 60549098868 scopus 로고    scopus 로고
    • Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America
    • Pappas P.G., Kauffman C.A., andes D., Benjamin D.K., Calandra T.F., Edwards J.E., et al. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 2009, 48:503-535.
    • (2009) Clin Infect Dis , vol.48 , pp. 503-535
    • Pappas, P.G.1    Kauffman, C.A.2    Andes, D.3    Benjamin, D.K.4    Calandra, T.F.5    Edwards, J.E.6
  • 9
    • 65749096905 scopus 로고    scopus 로고
    • Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance
    • Tsao S., Rahkhoodaee F., Raymond M. Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance. Antimicrob Agents Chemother 2009, 53:1344-1352.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 1344-1352
    • Tsao, S.1    Rahkhoodaee, F.2    Raymond, M.3
  • 10
    • 77749291956 scopus 로고    scopus 로고
    • Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature
    • Morio F., Loge C., Besse B., Hennequin C., Le Pape P. Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature. Diagn Microbiol Infect Dis 2010, 66:373-384.
    • (2010) Diagn Microbiol Infect Dis , vol.66 , pp. 373-384
    • Morio, F.1    Loge, C.2    Besse, B.3    Hennequin, C.4    Le Pape, P.5
  • 12
    • 84865368550 scopus 로고    scopus 로고
    • Amino acid substitutions in the Candida albicans sterol Delta5,6-desaturase (Erg3p) confer azole resistance: characterization of two novel mutants with impaired virulence
    • Morio F., Pagniez F., Lacroix C., Miegeville M., Le Pape P. Amino acid substitutions in the Candida albicans sterol Delta5,6-desaturase (Erg3p) confer azole resistance: characterization of two novel mutants with impaired virulence. J Antimicrob Chemother 2012, 67:2131-2138.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 2131-2138
    • Morio, F.1    Pagniez, F.2    Lacroix, C.3    Miegeville, M.4    Le Pape, P.5
  • 13
    • 0034812585 scopus 로고    scopus 로고
    • Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patients
    • Perea S., Lopez-Ribot J.L., Kirkpatrick W.R., McAtee R.K., Santillan R.A., Martinez M., et al. Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patients. Antimicrob Agents Chemother 2001, 45:2676-2684.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 2676-2684
    • Perea, S.1    Lopez-Ribot, J.L.2    Kirkpatrick, W.R.3    McAtee, R.K.4    Santillan, R.A.5    Martinez, M.6
  • 15
    • 84885423640 scopus 로고    scopus 로고
    • Deciphering azole resistance mechanisms with a focus on transcription factor-encoding genes TAC1, MRR1 and UPC2 in a set of fluconazole-resistant clinical isolates of Candida albicans
    • Morio F., Pagniez F., Besse M., Gay-andrieu F., Miegeville M., Le Pape P. Deciphering azole resistance mechanisms with a focus on transcription factor-encoding genes TAC1, MRR1 and UPC2 in a set of fluconazole-resistant clinical isolates of Candida albicans. Int J Antimicrob Agents 2013, 42:410-415.
    • (2013) Int J Antimicrob Agents , vol.42 , pp. 410-415
    • Morio, F.1    Pagniez, F.2    Besse, M.3    Gay-andrieu, F.4    Miegeville, M.5    Le Pape, P.6
  • 17
    • 84875276783 scopus 로고    scopus 로고
    • Mechanisms of azole resistance in 52 clinical isolates of Candida tropicalis in China
    • Jiang C., Dong D., Yu B., Cai G., Wang X., Ji Y., et al. Mechanisms of azole resistance in 52 clinical isolates of Candida tropicalis in China. J Antimicrob Chemother 2013, 68:778-785.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 778-785
    • Jiang, C.1    Dong, D.2    Yu, B.3    Cai, G.4    Wang, X.5    Ji, Y.6
  • 18
    • 0025096435 scopus 로고
    • Flow cytometry as a tool to discriminate respiratory-competent and respiratory-deficient yeast cells
    • Skowronek P.K.G., Haferkamp O., Rodel G. Flow cytometry as a tool to discriminate respiratory-competent and respiratory-deficient yeast cells. Curr Genet 1990, 18:265-267.
    • (1990) Curr Genet , vol.18 , pp. 265-267
    • Skowronek, P.K.G.1    Haferkamp, O.2    Rodel, G.3
  • 19
    • 0026323259 scopus 로고
    • Distribution of repetitive DNA sequences in eubacteria and application to fingerprinting of bacterial genomes
    • Versalovic J., Koeuth T., Lupski J.R. Distribution of repetitive DNA sequences in eubacteria and application to fingerprinting of bacterial genomes. Nucleic Acids Res 1991, 19:6823-6831.
    • (1991) Nucleic Acids Res , vol.19 , pp. 6823-6831
    • Versalovic, J.1    Koeuth, T.2    Lupski, J.R.3
  • 20
    • 84877642562 scopus 로고    scopus 로고
    • Erg11 mutations associated with azole resistance in clinical isolates of Candida albicans
    • Xiang M.J., Liu J.Y., Ni P.H., Wang S., Shi C., Wei B., et al. Erg11 mutations associated with azole resistance in clinical isolates of Candida albicans. FEMS Yeast Res 2013, 13:386-393.
    • (2013) FEMS Yeast Res , vol.13 , pp. 386-393
    • Xiang, M.J.1    Liu, J.Y.2    Ni, P.H.3    Wang, S.4    Shi, C.5    Wei, B.6
  • 21
    • 0023134858 scopus 로고
    • Interaction of azole antifungal agents with cytochrome P-45014DM purified from Saccharomyces cerevisiae microsomes
    • Yoshida Y., Aoyama Y. Interaction of azole antifungal agents with cytochrome P-45014DM purified from Saccharomyces cerevisiae microsomes. Biochem Pharmacol 1987, 36:229-235.
    • (1987) Biochem Pharmacol , vol.36 , pp. 229-235
    • Yoshida, Y.1    Aoyama, Y.2
  • 22
    • 0036488166 scopus 로고    scopus 로고
    • Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences
    • Sanglard D., Odds F.C. Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences. Lancet Infect Dis 2002, 2:73-85.
    • (2002) Lancet Infect Dis , vol.2 , pp. 73-85
    • Sanglard, D.1    Odds, F.C.2
  • 23
    • 2542494102 scopus 로고    scopus 로고
    • Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles
    • Chau A.S., Mendrick C.A., Sabatelli F.J., Loebenberg D., McNicholas P.M. Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles. Antimicrob Agents Chemother 2004, 48:2124-2131.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2124-2131
    • Chau, A.S.1    Mendrick, C.A.2    Sabatelli, F.J.3    Loebenberg, D.4    McNicholas, P.M.5
  • 24
    • 11144270183 scopus 로고    scopus 로고
    • TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2
    • Coste A.T., Karababa M., Ischer F., Bille J., Sanglard D. TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2. Eukaryot Cell 2004, 3:1639-1652.
    • (2004) Eukaryot Cell , vol.3 , pp. 1639-1652
    • Coste, A.T.1    Karababa, M.2    Ischer, F.3    Bille, J.4    Sanglard, D.5
  • 25
    • 33646171879 scopus 로고    scopus 로고
    • A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans
    • Coste A., Turner V., Ischer F., Morschhauser J., Forche A., Selmecki A., et al. A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans. Genetics 2006, 172:2139-2156.
    • (2006) Genetics , vol.172 , pp. 2139-2156
    • Coste, A.1    Turner, V.2    Ischer, F.3    Morschhauser, J.4    Forche, A.5    Selmecki, A.6
  • 26
    • 26444574876 scopus 로고    scopus 로고
    • Establishing surrogate markers for fluconazole resistance in Candida albicans
    • Park S., Perlin D.S. Establishing surrogate markers for fluconazole resistance in Candida albicans. Microb Drug Resist 2005, 11:232-238.
    • (2005) Microb Drug Resist , vol.11 , pp. 232-238
    • Park, S.1    Perlin, D.S.2
  • 28
    • 84858663078 scopus 로고    scopus 로고
    • Azole resistance by loss of function of the sterol Delta(5),(6)-desaturase gene (ERG3) in Candida albicans does not necessarily decrease virulence
    • Vale-Silva L.A., Coste A.T., Ischer F., Parker J.E., Kelly S.L., Pinto E., et al. Azole resistance by loss of function of the sterol Delta(5),(6)-desaturase gene (ERG3) in Candida albicans does not necessarily decrease virulence. Antimicrob Agents Chemother 2012, 56:1960-1968.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 1960-1968
    • Vale-Silva, L.A.1    Coste, A.T.2    Ischer, F.3    Parker, J.E.4    Kelly, S.L.5    Pinto, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.