Invasive candidiasis in intensive care units in China: A multicentre prospective observational study

Journal of Antimicrobial Chemotherapy

Volumn 68, Issue 7, 2013, Pages 1660-1668

  Guo, Fengmei ^a   Yang, Yi ^a   Kang, Yan ^b   Zang, Bin ^c   Cui, Wei ^d   Qin, Bingyu ^e   Qin, Yingzhi ^f   Fang, Qiang ^g   Qin, Tiehe ^h   Jiang, Dongpo ⁱ   Li, Weiqin ^j   Gu, Qin ^k   Zhao, Hongsheng ^l   Liu, Dawei ^m   Guan, Xiangdong ⁿ   Li, Jianguo ^o   Ma, Xiaochun ^c   Yu, Kaijiang ^p   Chan, Dechang ^q   Yan, Jing ^r   Tang, Yaoqing ^s   Liu, Wei ^t   Li, Ruoyu ^t   Qiu, Haibo ^a   more..

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c CHINA MEDICAL UNIVERSITY   (China)

^d THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^e HENAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

^f TIANJIN THIRD CENTRAL HOSPITAL   (China)

^g ZHEJIANG UNIVERSITY   (China)

^h GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

ⁱ THIRD MILITARY MEDICAL UNIVERSITY   (China)

^j JINLING HOSPITAL   (China)

^k MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^l NANTONG UNIVERSITY   (China)

^m PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

ⁿ SUN YAT SEN UNIVERSITY   (China)

^o ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^p HARBIN MEDICAL UNIVERSITY   (China)

^q SECOND MILITARY MEDICAL UNIVERSITY   (China)

^r ZHEJIANG HOSPITAL   (China)

^s SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^t PEKING UNIVERSITY FIRST HOSPITAL   (China)

more..

Author keywords

Antifungal; Candida albicans; ICUs; Invasive Candida infection

Indexed keywords

CARBAPENEM DERIVATIVE; CEPHALOSPORIN DERIVATIVE; ECHINOCANDIN; FLUCONAZOLE; GLYCOPEPTIDE; PENICILLIN DERIVATIVE; QUINOLONE DERIVATIVE; TRIAZOLE DERIVATIVE;

ABDOMINAL SURGERY; ADULT; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; ARTIFICIAL VENTILATION; ASCITES FLUID; BACTERIAL STRAIN; BLOOD CULTURE; CANDIDA ALBICANS; CATHETERIZATION; CENTRAL VENOUS CATHETER; CHINA; COMORBIDITY; CYTOPATHOLOGY; DIAGNOSTIC PROCEDURE; DIGESTIVE SYSTEM FUNCTION DISORDER; DISEASE PREDISPOSITION; DRAINAGE TUBE; FEMALE; FINE NEEDLE ASPIRATION BIOPSY; HISTOPATHOLOGY; HOSPITAL INFECTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOSUPPRESSIVE TREATMENT; INCIDENCE; INTENSIVE CARE UNIT; INVASIVE CANDIDIASIS; MALE; MONOTHERAPY; MORTALITY; MULTICENTER STUDY; NEUTROPENIA; OBSERVATIONAL STUDY; PLEURA EFFUSION; RISK FACTOR; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; TOTAL PARENTERAL NUTRITION; TREATMENT DURATION; TREATMENT OUTCOME; YEAST CELL;

EID: 84879480870     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt083     Document Type: Article

References (42)

1. Méan M, Marchetti O, Calandra T. Bench-to-bedside review: Candida infections in the intensive care unit. Crit Care 2008; 12: 204.
2. Kett D, Azoulay E, Echeverria P et al. Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study. Crit Care Med 2011; 39: 665-70.
3. Falagas M, Roussos N, Vardakas K. Relative frequency of albicans and non-6albicans Candida spp among candidemia isolates from inpatients in various parts of the world: a systematic review. Int J Infect Dis 2010; 14: e954-66.
4. Horn DL, Neofytos D, Anaissie EJ, et al. Epidemiology and outcomes of candidemia in 2019 patients: data from the prospective antifungal therapy alliance registry. Clin Infect Dis 2009; 48: 1695-703.
5. Concia E, Azzini AM, Conti M. Epidemiology, incidence and risk factors for invasive candidiasis in high-risk patients. Drugs 2009; 69 Suppl 1: 5-14.
6. Vincent JL, Rello J, Marshall J, et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA 2009; 302: 2323-9.
7. Olaechea P.M.,Palomar M, Leó n-232Gil C, et al. Economic impact of Candida colonization and Candida infection in the critically ill patient. Eur J Clin Microbiol Infect Dis 2004; 23: 323-30.
8. Xie GH, Fang XM, Fang Q, et al. Impact of invasive fungal infection on outcomes of severe sepsis: a multicenter matched cohort study in critically ill surgical patients. Crit Care 2008; 12: R5.
9. Vazquez JA. Invasive fungal infections in the intensive care unit. Semin Respir Crit Care Med 2010; 31: 79-86.
10. Kriengkauykiat J, Ito JI, Dadwal SS. Epidemiology and treatment approaches in management of invasive fungal infections. Clin Epidemiol 2011; 3: 175-91.
11. Pfaller MA, Diekema DJ. Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev 2007; 20: 133-63.
12. Bassetti M, Righi E, Costa A, et al. Epidemiological trends in nosocomial candidemia in intensive care. BMC Infect Dis 2006; 6: 21.
13. Cruciani M, Serpelloni G. Management of Candida infections in the adult intensive care unit. Expert Opin Pharmacother 2008; 9: 175-91.
14. Cao B, Wang H, Wu L, et al. [Epidemiological study of invasive nosocomial candidiasis in 2 teaching hospitals in Beijing]. Zhonghua Yi Xue Za Zhi 2008; 88: 1970-3.
15. Garey KW, Rege M, Pai MP, et al. Time to initiation of fluconazole therapy impacts mortality in patients with candidemia: a multi-institutional study. Clin Infect Dis 2006; 43: 25-31.
16. Parkins MD, Sabuda DM, Elsayed S, et al. Adequacy of empirical antifungal therapy and effect on outcome among patients with invasive Candida species infections. J Antimicrob Chemother 2007; 60: 613-8.
17. Morrell M, Fraser VJ, Kollef MH. Delaying the empiric treatment of Candida bloodstream infection until positive blood culture results are obtained: a potential risk factor for hospital mortality. Antimicrob Agents Chemother 2005; 49: 3640-5.
18. Marriott D, Playford E, Chen S, et al. Australian Candidaemia Study. Determinants of mortality in non-neutropenic ICU patients with candidaemia. Crit Care 2009; 13: R115.
19. Ibrahim EH, Sherman G, Ward S, et al. The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest 2000; 118: 146-55.
20. Critical Care Medicine Branch of the Chinese Medical Association. Diagnostic and treatment guidelines for invasive fungal infection in critical ill patients (2007). Chinese J Int Med 2007; 46: 960-6.
21. FDA. General Principles of Software Validation; Final Guidance for Industry and FDA Staff. 2002. http://www.fda.gov/downloads/ RegulatoryInformation/Guidances/ucm126955.pdf (11 October 2012, date last accessed).
22. Clinical and Laboratory Standards Institute. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts: Approved Standard M27-A3. CLSI, Wayne, PA, USA, 2008.
23. Clinical and Laboratory Standards Institute. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts: Third Informational Supplement M27-S3. CLSI, Wayne, PA, USA, 2008.
24. Pfaller MA, Diekema DJ. Progress in antifungal susceptibility testing of Candida spp. by use of Clinical and Laboratory Standards Institute broth microdilution methods, 2010 to 2012. J Clin Microbiol 2012; 50: 2846-56.
25. Pfaller MA, Espinel-Ingroff A, Canton E, et al. Wild-type MIC distributions and epidemiological cutoff values for amphotericin B, flucytosine, and itraconazole and Candida spp. as determined by CLSI broth microdilution. J Clin Microbiol 2012; 50: 2040-6.
26. De Pauw B, Walsh TJ, Donnelly JP, et al. Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. Clin Infect Dis 2008; 46: 1813-21.
27. Bougnoux ME, Kac G, Aegerter P, et al. Candidemia and candiduria in critically ill patients admitted to intensive care units in France: incidence, molecular diversity, management and outcome. Intensive Care Med 2008; 34: 292-9.
28. Playford EG, Lipman J, Sorrell T. Management of invasive candidiasis in the intensive care unit. Drugs 2010; 70: 823-39.
29. Li S, An Y. Retrospective analysis of invasive fungal infection in surgical intensive care unit. Natl Med J China 2010; 90: 382-5.
30. Echeverria PM, Kett DH, Azoulay E. Candida prophylaxis and therapy in the ICU. Semin Respir Crit Care 2011; 32: 159-73.
31. Pfaller MA, Diekema DJ, Gibbs DL, et al. Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: a 10.5-year analysis of susceptibilities of Candida species to fluconazole and voriconazole as determined by CLSI standardized disk diffusion. J Clin Microbiol 2010; 48: 1366-77.
32. Zhu D, Zhang Y-Y, Wang F. Surveillance of resistance to fluconazole and voriconazole in Candida isolates from 5 hospitals in China. Chin J Infect Chemother 2007; 7: 14-8.
33. Bassetti M, Ansaldi F, Nicolini L, et al. Incidence of candidaemia and relationship with fluconazole use in an intensive care unit. J Antimicrob Chemother 2009; 64: 625-9.
34. Leroy O, Gangneux JP, Montravers P, et al. Epidemiology, management, and risk factors for death of invasive Candida infections in critical care: a multicenter, prospective, observational study in France (2005-2006). Crit Care Med 2009; 37: 1612-8.
35. Leroy O, Mira JP, Montravers P, et al. Comparison of albicans vs. nonalbicans candidemia in French intensive care units. Crit Care 2010; 14: R98.
36. Tortorano AM, Dho G, Prigitano A, et al. Invasive fungal infections in the intensive care unit: a multicentre, prospective, observational study in Italy (2006-14 2008). Mycoses 2012; 55: 73-9.
37. Bassetti M, Taramasso L, Nicco E, et al. Epidemiology, species distribution, antifungal susceptibility and outcome of nosocomial candidemia in a tertiary care hospital in Italy. PLoS ONE 2011; 6: e24198.
38. Yang H, Sun H. Clinic analysis of 38 critical patients with deep fungal infection. J Clin Pulmonary Med 2011; 16: 848-9.
39. Yin QQ, Zhang YT, Fang Q. [Study on the morbidity and pathogens of patients with candidemia at the intensive care unit]. Zhonghua Liu Xing Bing Xue Za Zhi 2008; 29: 464-8.
40. Cheng P, Zhang Y, Fang Q. Study on the epidemiology of fungi in intensive care unit of the First Affiliated Hospital of Zhejiang University. Chin J Crit Care Med 2009; 29: 13-7.
41. Huang L, Zhao L, Zhang W, et al. Comparison of risk factors for non-albicans Candida and Candida albicans infections in the intensive care unit. Chin J Postgrad Med 2010; 33: 6-9.
42. Sharma S, Kumar A. Antimicrobial management of sepsis and septic shock. Clin Chest Med 2008; 29: 677-87.