Correlation between infectivity and disease associated prion protein in the nervous system and selected edible tissues of naturally affected scrapie sheep

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Chianini, Francesca ^a   Cosseddu, Gian Mario ^b,d   Steele, Philip ^a   Hamilton, Scott ^a   Hawthorn, Jeremy ^c   Síso, Sílvia ^c,e   Pang, Yvonne ^a   Finlayson, Jeanie ^a   Eaton, Samantha L ^a,f   Reid, Hugh W ^a   Dagleish, Mark P ^a   Di Bari, Michele Angelo ^b   D'Agostino, Claudia ^b   Agrimi, Umberto ^b   Terry, Linda ^c   Nonno, Romolo ^b  

^a MOREDUN RESEARCH INSTITUTE   (United Kingdom)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c VETERINARY LABORATORIES AGENCY   (United Kingdom)

^d ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELL ABRUZZO E DEL MOLISE G CAPORALE   (Italy)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN; PRION;

ANIMAL TISSUE; ARTICLE; BIOASSAY; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRAOCULAR MUSCLE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY PARENCHYMA; LYMPH NODE; NONHUMAN; PREDICTIVE VALUE; PROTEIN UNFOLDING; SCIATIC NERVE; SCRAPIE; SHEEP; TISSUE DISTRIBUTION; VIRUS INFECTIVITY; WESTERN BLOTTING; ANIMAL; BRAIN; CHEMISTRY; KIDNEY; METABOLISM; MORTALITY; NERVOUS SYSTEM; PATHOLOGY; PRION; SURVIVAL ANALYSIS;

ANIMALIA; CLETHRIONOMYS GLAREOLUS; OVIS ARIES;

ANIMALS; BLOTTING, WESTERN; BRAIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; KIDNEY; LYMPH NODES; NERVOUS SYSTEM; OCULOMOTOR MUSCLES; PRIONS; SCIATIC NERVE; SCRAPIE; SHEEP; SURVIVAL ANALYSIS;

EID: 84926395777     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0122785     Document Type: Article

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