Chronic wasting disease and atypical forms of bovine spongiform encephalopathy and scrapie are not transmissible to mice expressing wild-type levels of human prion protein

Journal of General Virology

Volumn 93, Issue PART 7, 2012, Pages 1624-1629

  Wilson, Rona ^a   Plinston, Chris ^a   Hunter, Nora ^a   Casalone, Cristina ^b   Corona, Cristiano ^b   Tagliavini, Fabrizio ^c   Suardi, Silvia ^c   Ruggerone, Margherita ^c   Moda, Fabio ^c   Graziano, Silvia ^d   Sbriccoli, Marco ^d   Cardone, Franco ^d   Pocchiari, Maurizio ^d   Ingrosso, Loredana ^d   Baron, Thierry ^e   Richt, Juergen ^f,i   Andreoletti, Olivier ^g   Simmons, Marion ^h   Lockey, Richard ^h   Manson, Jean C ^a   Barron, Rona M ^a   more..

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b LIGURIA E VALLE D AOSTA   (Italy)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

^d ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^e Lyon Laboratory   (France)

^f AGRICULTURAL RESEARCH SERVICE   (United States)

^g CNRS   (France)

^h VETERINARY LABORATORIES AGENCY   (United Kingdom)

ⁱ KANSAS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BOVINE SPONGIFORM ENCEPHALOPATHY; CHRONIC WASTING DISEASE; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; DISEASE TRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCRAPIE;

ANIMALS; CATTLE; DEER; DISEASE MODELS, ANIMAL; ENCEPHALOPATHY, BOVINE SPONGIFORM; HUMANS; MICE; MICE, TRANSGENIC; PRIONS; RISK ASSESSMENT; SCRAPIE; SHEEP; WASTING DISEASE, CHRONIC; ZOONOSES;

EID: 84862679651     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.042507-0     Document Type: Article

References (37)

1. Angers, R. C., Browning, S. R., Seward, T. S., Sigurdson, C. J., Miller, M. W., Hoover, E. A. & Telling, G. C. (2006). Prions in skeletal muscles of deer with chronic wasting disease. Science 311, 1117.
2. Angers, R. C., Seward, T. S., Napier, D., Green, M., Hoover, E., Spraker, T., O'Rourke, K., Balachandran, A. & Telling, G. C. (2009). Chronic wasting disease prions in elk antler velvet. Emerg Infect Dis 15, 696-703.
3. Angers, R. C., Kang, H. E., Napier, D., Browning, S., Seward, T., Mathiason, C., Balachandran, A., McKenzie, D., Castilla, J. & other authors (2010). Prion strain mutation determined by prion protein conformational compatibility and primary structure. Science 328, 1154-1158.
4. Benestad, S. L., Sarradin, P., Thu, B., Schönheit, J., Tranulis, M. A. & Bratberg, B. (2003). Cases of scrapie with unusual features in Norway and designation of a new type, Nor98. Vet Rec 153, 202-208.
5. Benestad, S. L., Arsac, J. N., Goldmann, W. & Nöremark, M. (2008). Atypical/Nor98 scrapie: properties of the agent, genetics, and epidemiology. Vet Res 39, 19.
6. Béringue, V., Herzog, L., Reine, F., Le Dur, A., Casalone, C., Vilotte, J. L. & Laude, H. (2008). Transmission of atypical bovine prions to mice transgenic for human prion protein. Emerg Infect Dis 14, 1898-1901.
7. Béringue, V., Herzog, L., Jaumain, E., Reine, F., Sibille, P., Le Dur, A., Vilotte, J.-L. & Laude, H. (2012). Facilitated cross-species transmission of prions in extraneural tissue. Science 335, 472-475.
8. Biacabe, A. G., Laplanche, J. L., Ryder, S. & Baron, T. (2004). Distinct molecular phenotypes in bovine prion diseases. EMBO Rep 5, 110-115.
9. Bishop, M. T., Hart, P., Aitchison, L., Baybutt, H. N., Plinston, C., Thomson, V., Tuzi, N. L., Head, M. W., Ironside, J. W. & Will, R. G. (2006). Predicting susceptibility and incubation time of human-tohuman transmission of vCJD. Lancet Neurol 5, 393-398.
10. Bishop, M. T., Will, R. G. & Manson, J. C. (2010). Defining sporadic Creutzfeldt-Jakob disease strains and their transmission properties. Proc Natl Acad Sci U S A 107, 12005-12010.
11. Bruce, M. E., Will, R. G., Ironside, J. W., McConnell, I., Drummond, D., Suttie, A., McCardle, L., Chree, A., Hope, J. & other authors (1997). Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent. Nature 389, 498-501.
12. Casalone, C., Zanusso, G., Acutis, P., Ferrari, S., Capucci, L., Tagliavini, F., Monaco, S. & Caramelli, M. (2004). Identification of a second bovine amyloidotic spongiform encephalopathy: molecular similarities with sporadic Creutzfeldt-Jakob disease. Proc Natl Acad Sci U S A 101, 3065-3070.
13. Denkers, N. D., Seelig, D. M., Telling, G. C. & Hoover, E. A. (2010). Aerosol and nasal transmission of chronic wasting disease in cervidized mice. J Gen Virol 91, 1651-1658.
14. Dickinson, A. G., Meikle, V. M. & Fraser, H. (1968). Identification of a gene which controls the incubation period of some strains of scrapie agent in mice. J Comp Pathol 78, 293-299.
15. Fraser, H. & Dickinson, A. G. (1967). Distribution of experimentally induced scrapie lesions in the brain. Nature 216, 1310-1311.
16. Griffiths, P. C., Spiropoulos, J., Lockey, R., Tout, A. C., Jayasena, D., Plater, J. M., Chave, A., Green, R. B., Simonini, S. & other authors (2010). Characterization of atypical scrapie cases from Great Britain in transgenic ovine PrP mice. J Gen Virol 91, 2132-2138.
17. Haley, N. J., Seelig, D. M., Zabel, M. D., Telling, G. C. & Hoover, E. A. (2009). Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay. PLoS ONE 4, e4848.
18. Haley, N. J., Mathiason, C. K., Carver, S., Zabel, M., Telling, G. C. & Hoover, E. A. (2011). Detection of chronic wasting disease prions in salivary, urinary and intestinal tissues of deer: potential mechanisms of prion shedding and transmission. J Virol 85, 6309-6318.
19. Hill, A. F., Desbruslais, M., Joiner, S., Sidle, K. C. L., Gowland, I., Collinge, J., Doey, L. J. & Lantos, P. (1997). The same prion strain causes vCJD and BSE. Nature 389, 448-450, 526.
20. Jacobs, J. G., Langeveld, J. P., Biacabe, A. G., Acutis, P. L., Polak, M. P., Gavier-Widen, D., Buschmann, A., Caramelli, M., Casalone, C. & other authors (2007). Molecular discrimination of atypical bovine spongiform encephalopathy strains from a geographical region spanning a wide area in Europe. J Clin Microbiol 45, 1821-1829.
21. Kong, Q., Huang, S., Zou, W., Vanegas, D., Wang, M., Wu, D., Yuan, J., Zheng, M., Bai, H. & other authors (2005). Chronic wasting disease of elk: transmissibility to humans examined by transgenic mouse models. J Neurosci 25, 7944-7949.
22. Kong, Q., Zheng, M., Casalone, C., Qing, L., Huang, S., Chakraborty, B., Wang, P., Chen, F., Cali, I. & other authors (2008). Evaluation of the human transmission risk of an atypical bovine spongiform encephalopathy prion strain. J Virol 82, 3697-3701.
23. Mathiason, C. K., Powers, J. G., Dahmes, S. J., Osborn, D. A., Miller, K. V., Warren, R. J., Mason, G. L., Hays, S. A., Hayes-Klug, J. & other authors (2006). Infectious prions in the saliva and blood of deer with chronic wasting disease. Science 314, 133-136.
24. Mathiason, C. K., Hays, S. A., Powers, J., Hayes-Klug, J., Langenberg, J., Dahmes, S. J., Osborn, D. A., Miller, K. V., Warren, R. J. & other authors (2009). Infectious prions in pre-clinical deer and transmission of chronic wasting disease solely by environmental exposure. PLoS ONE 4, e5916.
25. Miller, M. W. & Williams, E. S. (2003). Prion disease: horizontal prion transmission in mule deer. Nature 425, 35-36.
26. Miller, M. W., Wild, M. A. & Williams, E. S. (1998). Epidemiology of chronic wasting disease in captive Rocky Mountain elk. J Wildl Dis 34, 532-538.
27. Plinston, C., Hart, P., Chong, A., Hunter, N., Foster, J., Piccardo, P., Manson, J. C. & Barron, R. M. (2011). Increased susceptibility of human-PrP transgenic mice to bovine spongiform encephalopathy infection following passage in sheep. J Virol 85, 1174-1181.
28. Race, B. L., Meade-White, K. D., Ward, A., Jewell, J., Miller, M. W., Williams, E. S., Chesebro, B. & Race, R. E. (2007). Levels of abnormal prion protein in deer and elk with chronic wasting disease. Emerg Infect Dis 13, 824-830.
29. Race, B., Meade-White, K., Race, R. & Chesebro, B. (2009a). Prion infectivity in fat of deer with chronic wasting disease. J Virol 83, 9608- 9610.
30. Race, B., Meade-White, K. D., Miller, M. W., Barbian, K. D., Rubenstein, R., LaFauci, G., Cervenakova, L., Favara, C., Gardner, D. & other authors (2009b). Susceptibilities of nonhuman primates to chronic wasting disease. Emerg Infect Dis 15, 1366-1376.
31. Sandberg, M. K., Al-Doujaily, H., Sigurdson, C. J., Glatzel, M., O'Malley, C., Powell, C., Asante, E. A., Linehan, J. M., Brandner, S. &other authors (2010). Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein. J Gen Virol 91, 2651-2657.
32. Sigurdson, C. J., Williams, E. S., Miller, M. W., Spraker, T. R., O'Rourke, K. I. & Hoover, E. A. (1999). Oral transmission and early lymphoid tropism of chronic wasting disease PrPres in mule deer fawns (Odocoileus hemionus). J Gen Virol 80, 2757-2764.
33. Spraker, T. R., Zink, R. R., Cummings, B. A., Wild, M. A., Miller, M. W. & O'Rourke, K. I. (2002). Comparison of histological lesions and immunohistochemical staining of proteinase-resistant prion protein in a naturally occurring spongiform encephalopathy of free-ranging mule deer (Odocoileus hemionus) with those of chronic wasting disease of captive mule deer. Vet Pathol 39, 110-119.
34. Stack, M. J., Focosi-Snyman, R., Cawthraw, S., Davis, L., Chaplin, M. J. & Burke, P. J. (2009). Third atypical BSE case in Great Britain with an H-type molecular profile. Vet Rec 165, 605-606.
35. Tamgüney, G., Giles, K., Bouzamondo-Bernstein, E., Bosque, P. J., Miller, M. W., Safar, J., DeArmond, S. J. & Prusiner, S. B. (2006). Transmission of elk and deer prions to transgenic mice. J Virol 80, 9104-9114.
36. Trifilo, M. J., Ying, G., Teng, C. & Oldstone, M. B. (2007). Chronic wasting disease of deer and elk in transgenic mice: oral transmission and pathobiology. Virology 365, 136-143.
37. Wilson, R., Hart, P., Piccardo, P., Hunter, N., Casalone, C., Baron, T. & Barron, R. (2012). Bovine PrP expression levels in transgenic mice influence transmission characteristics of atypical BSE. J Gen Virol 93, 1132-1140.