-
1
-
-
84880264045
-
Cdks, cyclins and CKIs: Roles beyond cell cycle regulation
-
Lim S, Kaldis P. Cdks, cyclins and CKIs: roles beyond cell cycle regulation. Development. 2013;140(15):3079-3093.
-
(2013)
Development
, vol.140
, Issue.15
, pp. 3079-3093
-
-
Lim, S.1
Kaldis, P.2
-
3
-
-
60749109846
-
Cell cycle, CDKs and cancer: A changing paradigm
-
Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer. 2009;9(3):153-166.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.3
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
4
-
-
84879102756
-
ATP-noncompetitive CDK inhibitors for cancer therapy: An overview
-
Abate AA, Pentimalli F, Esposito L, Giordano A. ATP-noncompetitive CDK inhibitors for cancer therapy: an overview. Expert Opin Investig Drugs. 2013; 22(7):895-906.
-
(2013)
Expert Opin Investig Drugs
, vol.22
, Issue.7
, pp. 895-906
-
-
Abate, A.A.1
Pentimalli, F.2
Esposito, L.3
Giordano, A.4
-
5
-
-
37549036250
-
CDK inhibitors in cancer therapy: What is next?
-
Malumbres M, Pevarello P, Barbacid M, Bischoff JR. CDK inhibitors in cancer therapy: what is next? Trends Pharmacol Sci. 2008;29(1):16-21.
-
(2008)
Trends Pharmacol Sci
, vol.29
, Issue.1
, pp. 16-21
-
-
Malumbres, M.1
Pevarello, P.2
Barbacid, M.3
Bischoff, J.R.4
-
6
-
-
0142116249
-
Cdk2 knockout mice are viable
-
Berthet C, Aleem E, Coppola V, Tessarollo L, Kaldis P. Cdk2 knockout mice are viable. Curr Biol. 2003;13(20):1775-1785.
-
(2003)
Curr Biol
, vol.13
, Issue.20
, pp. 1775-1785
-
-
Berthet, C.1
Aleem, E.2
Coppola, V.3
Tessarollo, L.4
Kaldis, P.5
-
7
-
-
4444247138
-
Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6
-
Malumbres M, Sotillo R, Santamaria D, et al. Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell. 2004;118(4):493-504.
-
(2004)
Cell
, vol.118
, Issue.4
, pp. 493-504
-
-
Malumbres, M.1
Sotillo, R.2
Santamaria, D.3
-
8
-
-
0041854279
-
Cyclindependent kinase 2 is essential for meiosis but not for mitotic cell division in mice
-
Ortega S, Prieto I, Odajima J, et al. Cyclindependent kinase 2 is essential for meiosis but not for mitotic cell division in mice. Nat Genet. 2003;35(1):25-31.
-
(2003)
Nat Genet
, vol.35
, Issue.1
, pp. 25-31
-
-
Ortega, S.1
Prieto, I.2
Odajima, J.3
-
9
-
-
0032937751
-
Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in -islet cell hyperplasia
-
Rane SG, Dubus P, Mettus RV, et al. Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in -islet cell hyperplasia. Nat Genet. 1999;22 (5):44-52.
-
(1999)
At Genet
, vol.2
, Issue.5
, pp. 4-52
-
-
Rane, S.G.1
Dubus, P.2
Mettus, R.V.3
-
10
-
-
0032849353
-
Targeted disruption of CDK4 delays cell cycle entry with enhanced p27Kip1 activity
-
Tsutsui T, Hesabi B, Moons DS, et al. Targeted disruption of CDK4 delays cell cycle entry with enhanced p27Kip1 activity. Mol Cell Biol. 1999;19(10):7011-7019.
-
(1999)
Mol Cell Biol
, vol.19
, Issue.10
, pp. 7011-7019
-
-
Tsutsui, T.1
Hesabi, B.2
Moons, D.S.3
-
11
-
-
33646528191
-
Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation
-
Berthet C, Klarmann KD, Hilton MB, et al. Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell. 2006;10(5):563-573.
-
(2006)
Dev Cell
, vol.10
, Issue.5
, pp. 563-573
-
-
Berthet, C.1
Klarmann, K.D.2
Hilton, M.B.3
-
12
-
-
34547952048
-
Cdk1 is sufficient to drive the mammalian cell cycle
-
Santamaria D, Barriere C, Cerqueira A, et al. Cdk1 is sufficient to drive the mammalian cell cycle. Nature. 2007; 448(7155):811-815.
-
(2007)
Nature
, vol.448
, Issue.7155
, pp. 811-815
-
-
Santamaria, D.1
Barriere, C.2
Cerqueira, A.3
-
13
-
-
58849151285
-
Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G1/S transition
-
Li W, Kotoshiba S, Berthet C, Hilton MB, Kaldis P. Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G1/S transition. Proc Natl Acad Sci USA. 2009;106(2):486-491.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.2
, pp. 486-491
-
-
Li, W.1
Kotoshiba, S.2
Berthet, C.3
Hilton, M.B.4
Kaldis, P.5
-
14
-
-
6444245017
-
VavCre transgenic mice: A tool for mutagenesis in hematopoietic and endothelial lineages
-
Georgiades P, Ogilvy S, Duval H, et al. vavCre transgenic mice: a tool for mutagenesis in hematopoietic and endothelial lineages. Genesis. 2002;34(4):251-256.
-
(2002)
Genesis
, vol.34
, Issue.4
, pp. 251-256
-
-
Georgiades, P.1
Ogilvy, S.2
Duval, H.3
-
15
-
-
0034656212
-
Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
-
Marino S, Vooijs M, van Der Gulden H, Jonkers J, Berns A. Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev. 2000;14(8):994-1004.
-
(2000)
Genes Dev
, vol.14
, Issue.8
, pp. 994-1004
-
-
Marino, S.1
Vooijs, M.2
Van Der Gulden, H.3
Jonkers, J.4
Berns, A.5
-
16
-
-
84857956418
-
Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration
-
Diril MK, Ratnacaram CK, Padmakumar VC, et al. Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration. Proc Natl Acad Sci USA. 2012;109(10):3826-3831.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.10
, pp. 3826-3831
-
-
Diril, M.K.1
Ratnacaram, C.K.2
Padmakumar, V.C.3
-
17
-
-
78650053515
-
Down-regulation of Myc is essential for terminal erythroid maturation
-
Jayapal SR, Lee KL, Ji P, Kaldis P, Lim B, Lodish HF. Down-regulation of Myc is essential for terminal erythroid maturation. J Biol Chem. 2010;285(51):40252-40265.
-
(2010)
J Biol Chem
, vol.285
, Issue.51
, pp. 40252-40265
-
-
Jayapal, S.R.1
Lee, K.L.2
Ji, P.3
Kaldis, P.4
Lim, B.5
Lodish, H.F.6
-
18
-
-
84866600774
-
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number
-
Sankaran VG, Ludwig LS, Sicinska E, et al. Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number. Genes Dev. 2012;26(18):2075-2087.
-
(2012)
Genes Dev
, vol.26
, Issue.18
, pp. 2075-2087
-
-
Sankaran, V.G.1
Ludwig, L.S.2
Sicinska, E.3
-
19
-
-
0348191246
-
E2F4 is essential for normal erythrocyte maturation and neonatal viability
-
Humbert PO, Rogers C, Ganiatsas S, et al. E2F4 is essential for normal erythrocyte maturation and neonatal viability. Mol Cell. 2000;6(2):281-291.
-
(2000)
Mol Cell
, vol.6
, Issue.2
, pp. 281-291
-
-
Humbert, P.O.1
Rogers, C.2
Ganiatsas, S.3
-
20
-
-
33746607668
-
E2f4 regulates fetal erythropoiesis through the promotion of cellular proliferation
-
Kinross KM, Clark AJ, Iazzolino RM, Humbert PO. E2f4 regulates fetal erythropoiesis through the promotion of cellular proliferation. Blood. 2006;108(3):886-895.
-
(2006)
Blood
, vol.108
, Issue.3
, pp. 886-895
-
-
Kinross, K.M.1
Clark, A.J.2
Iazzolino, R.M.3
Humbert, P.O.4
-
21
-
-
0346930623
-
Loss of E2F4 activity leads to abnormal development of multiple cellular lineages
-
Rempel RE, Saenz-Robles MT, Storms R, et al. Loss of E2F4 activity leads to abnormal development of multiple cellular lineages. Mol Cell. 2000;6(2):293-306.
-
(2000)
Mol Cell
, vol.6
, Issue.2
, pp. 293-306
-
-
Rempel, R.E.1
Saenz-Robles, M.T.2
Storms, R.3
-
22
-
-
83455220200
-
From stem cell to red cell: Regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications
-
Hattangadi SM, Wong P, Zhang L, Flygare J, Lodish HF. From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications. Blood. 2011;118(24):6258-6268.
-
(2011)
Blood
, vol.118
, Issue.24
, pp. 6258-6268
-
-
Hattangadi, S.M.1
Wong, P.2
Zhang, L.3
Flygare, J.4
Lodish, H.F.5
-
23
-
-
0028820191
-
Terminal differentiation of normal chicken erythroid progenitors: Shortening of G1 correlates with loss of Dcyclin?cdk4 expression and altered cell size control
-
Dolznig H, Bartunek P, Nasmyth K, Mullner EW, Beug H. Terminal differentiation of normal chicken erythroid progenitors: shortening of G1 correlates with loss of Dcyclin?cdk4 expression and altered cell size control. Cell Growth Differ. 1995;6(11):1341-1352.
-
(1995)
Cell Growth Differ
, vol.6
, Issue.11
, pp. 1341-1352
-
-
Dolznig, H.1
Bartunek, P.2
Nasmyth, K.3
Mullner, E.W.4
Beug, H.5
-
24
-
-
0024369746
-
Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population
-
Nowakowski RS, Lewin SB, Miller MW. Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population. J Neurocytol. 1989;18(3):311-318.
-
(1989)
J Neurocytol
, vol.18
, Issue.3
, pp. 311-318
-
-
Nowakowski, R.S.1
Lewin, S.B.2
Miller, M.W.3
-
25
-
-
40249094627
-
Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2
-
Ji P, Jayapal SR, Lodish HF. Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2. Nat Cell Biol. 2008;10(3):314-321.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.3
, pp. 314-321
-
-
Ji, P.1
Jayapal, S.R.2
Lodish, H.F.3
-
26
-
-
0344826470
-
Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: Functional analysis by a flow cytometry-based novel culture system
-
Zhang J, Socolovsky M, Gross AW, Lodish HF. Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture system. Blood. 2003;102(12):3938-3946.
-
(2003)
Blood
, vol.102
, Issue.12
, pp. 3938-3946
-
-
Zhang, J.1
Socolovsky, M.2
Gross, A.W.3
Lodish, H.F.4
-
27
-
-
0029863840
-
Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts
-
Herrera RE, Sah VP, Williams BO, Makela TP, Weinberg RA, Jacks T. Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts. Mol Cell Biol. 1996;16(5):2402-2407.
-
(1996)
Mol Cell Biol
, vol.16
, Issue.5
, pp. 2402-2407
-
-
Herrera, R.E.1
Sah, V.P.2
Williams, B.O.3
Makela, T.P.4
Weinberg, R.A.5
Jacks, T.6
-
28
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg RA. The retinoblastoma protein and cell cycle control. Cell. 1995;81(3):323-330.
-
(1995)
Cell
, vol.81
, Issue.3
, pp. 323-330
-
-
Weinberg, R.A.1
-
29
-
-
59149089409
-
A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis
-
Hu MG, Deshpande A, Enos M, et al. A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis. Cancer Res. 2009;69(3):810-818.
-
(2009)
Cancer Res
, vol.69
, Issue.3
, pp. 810-818
-
-
Hu, M.G.1
Deshpande, A.2
Enos, M.3
-
30
-
-
84862836329
-
Loss of Cdk2 and Cdk4 induces a switch from proliferation to differentiation in neural stem cells
-
Lim S, Kaldis P. Loss of Cdk2 and Cdk4 induces a switch from proliferation to differentiation in neural stem cells. Stem Cells. 2012;30(7):1509-1520.
-
(2012)
Stem Cells
, vol.30
, Issue.7
, pp. 1509-1520
-
-
Lim, S.1
Kaldis, P.2
-
31
-
-
33750493265
-
Cell size checkpoint control by the retinoblastoma tumor suppressor pathway
-
Fang SC, de los Reyes C, Umen JG. Cell size checkpoint control by the retinoblastoma tumor suppressor pathway. PLoS Genet. 2006;2(10):e167.
-
(2006)
Plos Genet
, vol.2
, Issue.10
-
-
Fang, S.C.1
De Los Reyes, C.2
Umen, J.G.3
-
32
-
-
0031594884
-
Differential modulation of G1-S-phase cyclin-dependent kinase 2/cyclin complexes occurs during the acquisition of a polyploid DNA content
-
Datta NS, Williams JL, Long MW. Differential modulation of G1-S-phase cyclin-dependent kinase 2/cyclin complexes occurs during the acquisition of a polyploid DNA content. Cell Growth Differ. 1998;9(8):639-650.
-
(1998)
Cell Growth Differ
, vol.9
, Issue.8
, pp. 639-650
-
-
Datta, N.S.1
Williams, J.L.2
Long, M.W.3
-
33
-
-
27244460633
-
The Evi1 proto-oncoprotein blocks endomitosis in megakaryocytes by inhibiting sustained cyclin-dependent kinase 2 catalytic activity
-
Kilbey A, Alzuherri H, McColl J, et al. The Evi1 proto-oncoprotein blocks endomitosis in megakaryocytes by inhibiting sustained cyclin-dependent kinase 2 catalytic activity. Br J Haematol. 2005;130(6):902-911.
-
(2005)
Br J Haematol
, vol.130
, Issue.6
, pp. 902-911
-
-
Kilbey, A.1
Alzuherri, H.2
McColl, J.3
-
34
-
-
34250006259
-
Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization
-
Muntean AG, Pang L, Poncz M, et al. Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization. Blood. 2007; 109(12):5199-5207.
-
(2007)
Blood
, vol.109
, Issue.12
, pp. 5199-5207
-
-
Muntean, A.G.1
Pang, L.2
Poncz, M.3
|