The Evi1 proto-oncoprotein blocks endomitosis in megakaryocytes by inhibiting sustained cyclin-dependent kinase 2 catalytic activity

British Journal of Haematology

Volumn 130, Issue 6, 2005, Pages 902-911

  Kilbey, Anna ^a,d   Alzuherri, Hadi ^a   McColl, Joan ^a   Calés, Carmela ^b   Frampton, Jonathan ^c   Bartholomew, Christopher ^a  

^a GLASGOW CALEDONIAN UNIVERSITY   (United Kingdom)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Cell cycle; Dysmegakaryopoiesis; Evi1; Leukaemia

Indexed keywords

CYCLIN DEPENDENT KINASE 2; MESSENGER RNA; PROTEIN; PROTEIN EVI1; UNCLASSIFIED DRUG; CDK2 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; DNA BINDING PROTEIN; EVI1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TUMOR PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL STIMULATION; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; ERYTHROLEUKEMIA; HUMAN; HUMAN CELL; MEGAKARYOCYTE; MOLECULAR DYNAMICS; PHENOTYPE; PRIORITY JOURNAL; STEM CELL; CELL CULTURE; CELL CYCLE; CYTOLOGY; DRUG ANTAGONISM; ENZYMOLOGY; HEMATOPOIESIS; METABOLISM; METHODOLOGY; MITOSIS; PATHOLOGY; PHYSIOLOGY; PROTO ONCOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CDC2-CDC28 KINASES; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE 2; DNA-BINDING PROTEINS; HEMATOPOIESIS; HUMANS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MEGAKARYOCYTES; MITOSIS; NEOPLASM PROTEINS; PROTO-ONCOGENES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 27244460633     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2005.05709.x     Document Type: Article

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