메뉴 건너뛰기




Volumn 8, Issue 2, 2015, Pages 1966-1975

Nicorandil inhibits oxidative stress and amyloid-β precursor protein processing in SH-SY5Y cells overexpressing APPsw

Author keywords

Alzheimer s disease; APP processing; Nicorandil; Oxidative stress; PI3K Akt GSK 3

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; AMYLOID PRECURSOR PROTEIN; GLIBENCLAMIDE; GLUTATHIONE; MALONALDEHYDE; NICORANDIL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SUPEROXIDE DISMUTASE;

EID: 84926365852     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (17)

References (42)
  • 1
    • 0026597063 scopus 로고
    • Alzheimer’s disease: The amyloid cascade hypothesis
    • Hardy JA, Higgins GA. Alzheimer’s disease: the amyloid cascade hypothesis. Science 1992; 256: 184-185.
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 2
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer’s disease: Progress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics. Science 2002; 297: 353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 3
    • 0037341012 scopus 로고    scopus 로고
    • Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death
    • Tai KK, McCrossan ZA, Abbott GW. Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death. J Neurochem 2003; 84: 1193-1200.
    • (2003) J Neurochem , vol.84 , pp. 1193-1200
    • Tai, K.K.1    McCrossan, Z.A.2    Abbott, G.W.3
  • 5
    • 0030050677 scopus 로고    scopus 로고
    • K+ channel openers protect hippocampal neurons against oxidative injury and amyloid-β peptide toxicity
    • Goodman Y, Mattson MP. K+ channel openers protect hippocampal neurons against oxidative injury and amyloid-β peptide toxicity. Brain Res 1996; 706: 328-332.
    • (1996) Brain Res , vol.706 , pp. 328-332
    • Goodman, Y.1    Mattson, M.P.2
  • 7
    • 0141918797 scopus 로고    scopus 로고
    • Nicorandil prevents oxidative stress-inducedapoptosis in neurons by activating mitochondrial ATP-sensitive potassium channels
    • Teshima Y, Akao M, Baumgartner WA, Marban E. Nicorandil prevents oxidative stress-inducedapoptosis in neurons by activating mitochondrial ATP-sensitive potassium channels. Brain Res 2003; 990: 45-50.
    • (2003) Brain Res , vol.990 , pp. 45-50
    • Teshima, Y.1    Akao, M.2    Baumgartner, W.A.3    Marban, E.4
  • 8
    • 84887245970 scopus 로고    scopus 로고
    • Effects of nicorandil in neuroprotective activation of PI3K/AKT pathways in a cellular model of Alzheimer’s disease
    • Kong J, Ren G, Jia N, Wang Y, Zhang H, Zhang W, Chen B, Cao Y. Effects of nicorandil in neuroprotective activation of PI3K/AKT pathways in a cellular model of Alzheimer’s disease. Eur Neurol 2013; 70: 233-241.
    • (2013) Eur Neurol , vol.70 , pp. 233-241
    • Kong, J.1    Ren, G.2    Jia, N.3    Wang, Y.4    Zhang, H.5    Zhang, W.6    Chen, B.7    Cao, Y.8
  • 9
    • 0029245289 scopus 로고
    • A potential role of apoptosis in neurodegeneration and Alzheimer’s disease
    • Cotman CW, Anderson AJ. A potential role of apoptosis in neurodegeneration and Alzheimer’s disease. Mol Neurobiol 1995; 10: 19-45.
    • (1995) Mol Neurobiol , vol.10 , pp. 19-45
    • Cotman, C.W.1    Erson, A.J.2
  • 10
    • 0032747486 scopus 로고    scopus 로고
    • Lassmann H. Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer’s disease. Evidence for apoptotic cell death
    • Stadelmann C, Deckwerth TL, Srinivasan A, Bancher C, Brück W, Jellinger K, Lassmann H. Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer’s disease. Evidence for apoptotic cell death. Am J Pathol 1999; 155: 1459-1466.
    • (1999) Am J Pathol , vol.155 , pp. 1459-1466
    • Stadelmann, C.1    Deckwerth, T.L.2    Srinivasan, A.3    Bancher, C.4    Brück, W.5    Jellinger, K.6
  • 12
    • 4744369310 scopus 로고    scopus 로고
    • Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology
    • Apelt J, Bigl M, Wunderlich P, Schliebs R. Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology. Int J Dev Neurosci 2004; 22: 475-484.
    • (2004) Int J Dev Neurosci , vol.22 , pp. 475-484
    • Apelt, J.1    Bigl, M.2    Wunderlich, P.3    Schliebs, R.4
  • 14
    • 0036591849 scopus 로고    scopus 로고
    • Lipid peroxidation and protein oxidation in Alzheimer’s disease brain: Potential causes and consequences involving β-peptide-associated free radical oxidative stress
    • Butterfield DA, Lauderback CM. Lipid peroxidation and protein oxidation in Alzheimer’s disease brain: potential causes and consequences involving β-peptide-associated free radical oxidative stress. Free Radic Biol Med 2002; 32: 1050-1060.
    • (2002) Free Radic Biol Med , vol.32 , pp. 1050-1060
    • Butterfield, D.A.1    Lauderback, C.M.2
  • 15
    • 0035369623 scopus 로고    scopus 로고
    • Transcription-dependent and-independent control of neuronal survival by the PI3K-Akt signaling pathway
    • Brunet A, Datta SR, Greenberg ME. Transcription-dependent and-independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr Opin Neurobiol 2001; 11: 297-305.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 297-305
    • Brunet, A.1    Datta, S.R.2    Greenberg, M.E.3
  • 16
    • 79960896430 scopus 로고    scopus 로고
    • Deficient brain insulin signalling pathway in Alzheimer’s disease and diabetes
    • Liu Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX. Deficient brain insulin signalling pathway in Alzheimer’s disease and diabetes. J Pathol 2011; 225: 54-62.
    • (2011) J Pathol , vol.225 , pp. 54-62
    • Liu, Y.1    Liu, F.2    Grundke-Iqbal, I.3    Iqbal, K.4    Gong, C.X.5
  • 17
    • 16944366762 scopus 로고    scopus 로고
    • Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and-insensitive mechanisms
    • Moule SK, Welsh GI, Edgell NJ, Foulstone EJ, Proud, CG, Denton RM. Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and-insensitive mechanisms. J Biol Chem 1997; 272: 7713-7719.
    • (1997) J Biol Chem , vol.272 , pp. 7713-7719
    • Moule, S.K.1    Welsh, G.I.2    Edgell, N.J.3    Foulstone, E.J.4    Proud, C.G.5    Denton, R.M.6
  • 18
    • 33645100144 scopus 로고    scopus 로고
    • Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway
    • Salkovic-Petrisic M, Tribl F, Schmidt M, Hoyer S, Riederer P. Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway. J Neurochem 2006; 96: 1005-1015.
    • (2006) J Neurochem , vol.96 , pp. 1005-1015
    • Salkovic-Petrisic, M.1    Tribl, F.2    Schmidt, M.3    Hoyer, S.4    Riederer, P.5
  • 19
    • 37049008884 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-kinase activation blocks amyloid beta-induced neurotoxicity
    • Lee KY, Koh SH, Noh MY, Kim SH, Lee YJ. Phosphatidylinositol-3-kinase activation blocks amyloid beta-induced neurotoxicity. Toxicology 2008; 243: 43-50.
    • (2008) Toxicology , vol.243 , pp. 43-50
    • Lee, K.Y.1    Koh, S.H.2    Noh, M.Y.3    Kim, S.H.4    Lee, Y.J.5
  • 20
    • 3343005434 scopus 로고    scopus 로고
    • PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: Effects of FAD mutations
    • Baki L, Shioi J, Wen P, Shao Z, Schwarzman A, Gama-Sosa M, Neve R, Robakis NK. PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations. EMBO J 2004; 23: 2586-2596.
    • (2004) EMBO J , vol.23 , pp. 2586-2596
    • Baki, L.1    Shioi, J.2    Wen, P.3    Shao, Z.4    Schwarzman, A.5    Gama-Sosa, M.6    Neve, R.7    Robakis, N.K.8
  • 21
    • 33745301487 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta and Alzheimer’s disease: Pathophysiological and therapeutic significance
    • Balaraman Y, Limaye AR, Levey, AI, Srinivasan S. Glycogen synthase kinase 3beta and Alzheimer’s disease: pathophysiological and therapeutic significance. Cell Mol Life Sci 2006; 63: 1226-1235.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 1226-1235
    • Balaraman, Y.1    Limaye, A.R.2    Levey, A.I.3    Srinivasan, S.4
  • 22
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995; 378: 785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Jelkovich, M.4    Hemmings, B.A.5
  • 23
    • 77950279899 scopus 로고    scopus 로고
    • Stimulation of neuronal KATP channels by cGMP-dependent protein kinase: Involvement of ROS and 5-hydroxydecanoate-sensitive factors in signal channels transduction
    • Chai Y, Lin YF. Stimulation of neuronal KATP channels by cGMP-dependent protein kinase: involvement of ROS and 5-hydroxydecanoate-sensitive factors in signal channels transduction. Am J Physiol Cell Physiol 2010; 298: C875-892.
    • (2010) Am J Physiol Cell Physiol , vol.298 , pp. C875-C892
    • Chai, Y.1    Lin, Y.F.2
  • 24
    • 2942586992 scopus 로고    scopus 로고
    • Activity-dependent increase in beta-amyloid precursor protein mRNA expression in neurons
    • Tabuchi A, Ishii A, Fukuchi M, Kobayashi S, Suzuki T, Tsuda M. Activity-dependent increase in beta-amyloid precursor protein mRNA expression in neurons. Neuroreport 2004; 15: 1329-1333.
    • (2004) Neuroreport , vol.15 , pp. 1329-1333
    • Tabuchi, A.1    Ishii, A.2    Fukuchi, M.3    Kobayashi, S.4    Suzuki, T.5    Tsuda, M.6
  • 25
    • 34547102265 scopus 로고    scopus 로고
    • Roles of amyloid-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer’s disease and mild cognitive impairment
    • Butterfield DA, Reed T, Newman SF, Sultana R. Roles of amyloid-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer’s disease and mild cognitive impairment. Free Radic Biol Med 2007; 43: 658-677.
    • (2007) Free Radic Biol Med , vol.43 , pp. 658-677
    • Butterfield, D.A.1    Reed, T.2    Newman, S.F.3    Sultana, R.4
  • 26
    • 67349253085 scopus 로고    scopus 로고
    • Oxidatively modified proteins in Alzheimer’s disease (AD), mild cognitive impairment and animal models of AD: Role of Abeta in pathogenesis
    • Sultana R, Perluigi M, Butterfield DA. Oxidatively modified proteins in Alzheimer’s disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis. Acta Neuropathol 2009; 118: 131-150.
    • (2009) Acta Neuropathol , vol.118 , pp. 131-150
    • Sultana, R.1    Perluigi, M.2    Butterfield, D.A.3
  • 27
    • 0035875690 scopus 로고    scopus 로고
    • Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis
    • Pratico D, Uryu K, Leight S, Trojanoswki JQ, Lee VM. Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. J Neurosci 2001; 21: 4183-4187.
    • (2001) J Neurosci , vol.21 , pp. 4183-4187
    • Pratico, D.1    Uryu, K.2    Leight, S.3    Trojanoswki, J.Q.4    Lee, V.M.5
  • 30
    • 0028200649 scopus 로고
    • Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative
    • Gabuzda D, Busciglio J, Chen LB, Matsudaira P, Yankner BA. Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative. J Biol Chem 1994; 269: 13623-13628.
    • (1994) J Biol Chem , vol.269 , pp. 13623-13628
    • Gabuzda, D.1    Busciglio, J.2    Chen, L.B.3    Matsudaira, P.4    Yankner, B.A.5
  • 32
    • 33947264635 scopus 로고    scopus 로고
    • Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer’s disease
    • Halagappa VK, Guo Z, Pearson M, Matsuoka Y, Cutler RG, Laferla FM, Mattson MP. Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer’s disease. Neurobiol Dis 2007; 26: 212-220.
    • (2007) Neurobiol Dis , vol.26 , pp. 212-220
    • Halagappa, V.K.1    Guo, Z.2    Pearson, M.3    Matsuoka, Y.4    Cutler, R.G.5    Laferla, F.M.6    Mattson, M.P.7
  • 34
    • 10744223843 scopus 로고    scopus 로고
    • Epigallocatechin gallate protects nerve growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase kinase-3
    • Koh SH, Kim SH, Kwon H, Park Y, Kim KS, Song CW, Kim J, Kim MH, Yu HJ, Henkel JS, Jung HK. Epigallocatechin gallate protects nerve growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase kinase-3. Brain Res Mol Brain Res 2003; 118: 72-81.
    • (2003) Brain Res Mol Brain Res , vol.118 , pp. 72-81
    • Koh, S.H.1    Kim, S.H.2    Kwon, H.3    Park, Y.4    Kim, K.S.5    Song, C.W.6    Kim, J.7    Kim, M.H.8    Yu, H.J.9    Henkel, J.S.10    Jung, H.K.11
  • 36
    • 81255135741 scopus 로고    scopus 로고
    • Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/BclXL-regulated mitochondrial apoptotic pathway
    • Zeng KW, Wang XM, Ko H, Kwon HC, Cha JW, Yang HO. Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/BclXL-regulated mitochondrial apoptotic pathway. Eur J Pharmacol 2011; 672: 45-55.
    • (2011) Eur J Pharmacol , vol.672 , pp. 45-55
    • Zeng, K.W.1    Wang, X.M.2    Ko, H.3    Kwon, H.C.4    Cha, J.W.5    Yang, H.O.6
  • 37
    • 79551543865 scopus 로고    scopus 로고
    • Implication of phosphatidylinositol-3 kinase/Akt/glycogen synthase kinase-3β pathway in ginsenoside Rb1’s attenuation of beta-amyloid-induced neurotoxicity and tau phosphorylation
    • Zhao R, Zhang Z, Song Y, Wang D, Qi J, Wen S. Implication of phosphatidylinositol-3 kinase/Akt/glycogen synthase kinase-3β pathway in ginsenoside Rb1’s attenuation of beta-amyloid-induced neurotoxicity and tau phosphorylation. J Ethnopharmaco 2011; 133: 1109-1116.
    • (2011) J Ethnopharmaco , vol.133 , pp. 1109-1116
    • Zhao, R.1    Zhang, Z.2    Song, Y.3    Wang, D.4    Qi, J.5    Wen, S.6
  • 38
    • 79959521714 scopus 로고    scopus 로고
    • Neuroprotective effects of linarin through activation of the PI3K/Akt pathway in amyloid-β-induced neuronal cell death
    • Lou H, Fan P, Perez RG, Lou H. Neuroprotective effects of linarin through activation of the PI3K/Akt pathway in amyloid-β-induced neuronal cell death. Bioorg Med Chem 2011; 19: 4021-4027.
    • (2011) Bioorg Med Chem , vol.19 , pp. 4021-4027
    • Lou, H.1    Fan, P.2    Perez, R.G.3    Lou, H.4
  • 39
    • 0035863188 scopus 로고    scopus 로고
    • Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
    • Lucas JJ, Hernández F, Gómez-Ramos P, Morán MA, Hen R Avila J. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J 2001; 20: 27-39.
    • (2001) EMBO J , vol.20 , pp. 27-39
    • Lucas, J.J.1    Hernández, F.2    Gómez-Ramos, P.3    Morán, M.A.4    Hen R Avila, J.5
  • 40
    • 33646922314 scopus 로고    scopus 로고
    • Full reversal of Alzheimer’s disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3
    • Engel T, Hernández F, Avila J, Lucas, JJ. Full reversal of Alzheimer’s disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3. J Neurosci 2006; 26: 5083-5090.
    • (2006) J Neurosci , vol.26 , pp. 5083-5090
    • Engel, T.1    Hernández, F.2    Avila, J.3    Lucas, J.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.