-
1
-
-
0026597063
-
Alzheimer’s disease: The amyloid cascade hypothesis
-
Hardy JA, Higgins GA. Alzheimer’s disease: the amyloid cascade hypothesis. Science 1992; 256: 184-185.
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
2
-
-
0037135111
-
The amyloid hypothesis of Alzheimer’s disease: Progress and problems on the road to therapeutics
-
Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics. Science 2002; 297: 353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
3
-
-
0037341012
-
Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death
-
Tai KK, McCrossan ZA, Abbott GW. Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death. J Neurochem 2003; 84: 1193-1200.
-
(2003)
J Neurochem
, vol.84
, pp. 1193-1200
-
-
Tai, K.K.1
McCrossan, Z.A.2
Abbott, G.W.3
-
4
-
-
9644253068
-
Targeting mitochondrial ATP-sensitive potassium channels
-
Busija DW, Lacza Z, Rajapakse N, Shimizu K, Kis B, Bari F, Domoki F, Horiguchi T. Targeting mitochondrial ATP-sensitive potassium channels: A novel approach to neuroprotection. Brain Res Brain Res Rev 2004; 46: 282-294.
-
(2004)
A Novel Approach to Neuroprotection. Brain Res Brain Res Rev
, vol.46
, pp. 282-294
-
-
Busija, D.W.1
Lacza, Z.2
Rajapakse, N.3
Shimizu, K.4
Kis, B.5
Bari, F.6
Domoki, F.7
Horiguchi, T.8
-
5
-
-
0030050677
-
K+ channel openers protect hippocampal neurons against oxidative injury and amyloid-β peptide toxicity
-
Goodman Y, Mattson MP. K+ channel openers protect hippocampal neurons against oxidative injury and amyloid-β peptide toxicity. Brain Res 1996; 706: 328-332.
-
(1996)
Brain Res
, vol.706
, pp. 328-332
-
-
Goodman, Y.1
Mattson, M.P.2
-
6
-
-
78650844057
-
The KATP Channel Activator Diazoxide Ameliorates Aβ and Tau Pathologies and Improves Memory in the 3xTgAD Mouse Model of Alzheimer’s Disease
-
Liu D, Pitta M, Lee JH, Ray B, Lahiri DK, Furukawa K, Mughal M, Jiang H, Villarreal J, Cutler RG, Greig NH, Mattson MP. The KATP Channel Activator Diazoxide Ameliorates Aβ and Tau Pathologies and Improves Memory in the 3xTgAD Mouse Model of Alzheimer’s Disease. J Alzheimers Dis 2010; 22: 443-457.
-
(2010)
J Alzheimers Dis
, vol.22
, pp. 443-457
-
-
Liu, D.1
Pitta, M.2
Lee, J.H.3
Ray, B.4
Lahiri, D.K.5
Furukawa, K.6
Mughal, M.7
Jiang, H.8
Villarreal, J.9
Cutler, R.G.10
Greig, N.H.11
Mattson, M.P.12
-
7
-
-
0141918797
-
Nicorandil prevents oxidative stress-inducedapoptosis in neurons by activating mitochondrial ATP-sensitive potassium channels
-
Teshima Y, Akao M, Baumgartner WA, Marban E. Nicorandil prevents oxidative stress-inducedapoptosis in neurons by activating mitochondrial ATP-sensitive potassium channels. Brain Res 2003; 990: 45-50.
-
(2003)
Brain Res
, vol.990
, pp. 45-50
-
-
Teshima, Y.1
Akao, M.2
Baumgartner, W.A.3
Marban, E.4
-
8
-
-
84887245970
-
Effects of nicorandil in neuroprotective activation of PI3K/AKT pathways in a cellular model of Alzheimer’s disease
-
Kong J, Ren G, Jia N, Wang Y, Zhang H, Zhang W, Chen B, Cao Y. Effects of nicorandil in neuroprotective activation of PI3K/AKT pathways in a cellular model of Alzheimer’s disease. Eur Neurol 2013; 70: 233-241.
-
(2013)
Eur Neurol
, vol.70
, pp. 233-241
-
-
Kong, J.1
Ren, G.2
Jia, N.3
Wang, Y.4
Zhang, H.5
Zhang, W.6
Chen, B.7
Cao, Y.8
-
9
-
-
0029245289
-
A potential role of apoptosis in neurodegeneration and Alzheimer’s disease
-
Cotman CW, Anderson AJ. A potential role of apoptosis in neurodegeneration and Alzheimer’s disease. Mol Neurobiol 1995; 10: 19-45.
-
(1995)
Mol Neurobiol
, vol.10
, pp. 19-45
-
-
Cotman, C.W.1
Erson, A.J.2
-
10
-
-
0032747486
-
Lassmann H. Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer’s disease. Evidence for apoptotic cell death
-
Stadelmann C, Deckwerth TL, Srinivasan A, Bancher C, Brück W, Jellinger K, Lassmann H. Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer’s disease. Evidence for apoptotic cell death. Am J Pathol 1999; 155: 1459-1466.
-
(1999)
Am J Pathol
, vol.155
, pp. 1459-1466
-
-
Stadelmann, C.1
Deckwerth, T.L.2
Srinivasan, A.3
Bancher, C.4
Brück, W.5
Jellinger, K.6
-
11
-
-
77955917442
-
Oxidative stress in Alzheimer disease: A possibility for prevention
-
Bonda DJ, Wang X, Perry G, Nunomura A, Tabaton M, Zhu X, Smith MA. Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology 2010; 59: 290-294.
-
(2010)
Neuropharmacology
, vol.59
, pp. 290-294
-
-
Bonda, D.J.1
Wang, X.2
Perry, G.3
Nunomura, A.4
Tabaton, M.5
Zhu, X.6
Smith, M.A.7
-
12
-
-
4744369310
-
Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology
-
Apelt J, Bigl M, Wunderlich P, Schliebs R. Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology. Int J Dev Neurosci 2004; 22: 475-484.
-
(2004)
Int J Dev Neurosci
, vol.22
, pp. 475-484
-
-
Apelt, J.1
Bigl, M.2
Wunderlich, P.3
Schliebs, R.4
-
13
-
-
38049098793
-
Oxidative stress activates a positive feedback between the gamma-and beta-secretase cleavages of the beta-amyloid precursor protein
-
Tamagno E, Guglielmotto M, Aragno M, Borghi R, Autelli R, Giliberto L, Muraca G, Danni O, Zhu X, Smith MA, Perry G, Jo DG, Mattson MP, Tabaton M. Oxidative stress activates a positive feedback between the gamma-and beta-secretase cleavages of the beta-amyloid precursor protein. J Neurochem 2008; 104: 683-695.
-
(2008)
J Neurochem
, vol.104
, pp. 683-695
-
-
Tamagno, E.1
Guglielmotto, M.2
Aragno, M.3
Borghi, R.4
Autelli, R.5
Giliberto, L.6
Muraca, G.7
Danni, O.8
Zhu, X.9
Smith, M.A.10
Perry, G.11
Jo, D.G.12
Mattson, M.P.13
Tabaton, M.14
-
14
-
-
0036591849
-
Lipid peroxidation and protein oxidation in Alzheimer’s disease brain: Potential causes and consequences involving β-peptide-associated free radical oxidative stress
-
Butterfield DA, Lauderback CM. Lipid peroxidation and protein oxidation in Alzheimer’s disease brain: potential causes and consequences involving β-peptide-associated free radical oxidative stress. Free Radic Biol Med 2002; 32: 1050-1060.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1050-1060
-
-
Butterfield, D.A.1
Lauderback, C.M.2
-
15
-
-
0035369623
-
Transcription-dependent and-independent control of neuronal survival by the PI3K-Akt signaling pathway
-
Brunet A, Datta SR, Greenberg ME. Transcription-dependent and-independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr Opin Neurobiol 2001; 11: 297-305.
-
(2001)
Curr Opin Neurobiol
, vol.11
, pp. 297-305
-
-
Brunet, A.1
Datta, S.R.2
Greenberg, M.E.3
-
16
-
-
79960896430
-
Deficient brain insulin signalling pathway in Alzheimer’s disease and diabetes
-
Liu Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX. Deficient brain insulin signalling pathway in Alzheimer’s disease and diabetes. J Pathol 2011; 225: 54-62.
-
(2011)
J Pathol
, vol.225
, pp. 54-62
-
-
Liu, Y.1
Liu, F.2
Grundke-Iqbal, I.3
Iqbal, K.4
Gong, C.X.5
-
17
-
-
16944366762
-
Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and-insensitive mechanisms
-
Moule SK, Welsh GI, Edgell NJ, Foulstone EJ, Proud, CG, Denton RM. Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and-insensitive mechanisms. J Biol Chem 1997; 272: 7713-7719.
-
(1997)
J Biol Chem
, vol.272
, pp. 7713-7719
-
-
Moule, S.K.1
Welsh, G.I.2
Edgell, N.J.3
Foulstone, E.J.4
Proud, C.G.5
Denton, R.M.6
-
18
-
-
33645100144
-
Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway
-
Salkovic-Petrisic M, Tribl F, Schmidt M, Hoyer S, Riederer P. Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway. J Neurochem 2006; 96: 1005-1015.
-
(2006)
J Neurochem
, vol.96
, pp. 1005-1015
-
-
Salkovic-Petrisic, M.1
Tribl, F.2
Schmidt, M.3
Hoyer, S.4
Riederer, P.5
-
19
-
-
37049008884
-
Phosphatidylinositol-3-kinase activation blocks amyloid beta-induced neurotoxicity
-
Lee KY, Koh SH, Noh MY, Kim SH, Lee YJ. Phosphatidylinositol-3-kinase activation blocks amyloid beta-induced neurotoxicity. Toxicology 2008; 243: 43-50.
-
(2008)
Toxicology
, vol.243
, pp. 43-50
-
-
Lee, K.Y.1
Koh, S.H.2
Noh, M.Y.3
Kim, S.H.4
Lee, Y.J.5
-
20
-
-
3343005434
-
PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: Effects of FAD mutations
-
Baki L, Shioi J, Wen P, Shao Z, Schwarzman A, Gama-Sosa M, Neve R, Robakis NK. PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations. EMBO J 2004; 23: 2586-2596.
-
(2004)
EMBO J
, vol.23
, pp. 2586-2596
-
-
Baki, L.1
Shioi, J.2
Wen, P.3
Shao, Z.4
Schwarzman, A.5
Gama-Sosa, M.6
Neve, R.7
Robakis, N.K.8
-
21
-
-
33745301487
-
Glycogen synthase kinase 3beta and Alzheimer’s disease: Pathophysiological and therapeutic significance
-
Balaraman Y, Limaye AR, Levey, AI, Srinivasan S. Glycogen synthase kinase 3beta and Alzheimer’s disease: pathophysiological and therapeutic significance. Cell Mol Life Sci 2006; 63: 1226-1235.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 1226-1235
-
-
Balaraman, Y.1
Limaye, A.R.2
Levey, A.I.3
Srinivasan, S.4
-
22
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995; 378: 785-789.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Jelkovich, M.4
Hemmings, B.A.5
-
23
-
-
77950279899
-
Stimulation of neuronal KATP channels by cGMP-dependent protein kinase: Involvement of ROS and 5-hydroxydecanoate-sensitive factors in signal channels transduction
-
Chai Y, Lin YF. Stimulation of neuronal KATP channels by cGMP-dependent protein kinase: involvement of ROS and 5-hydroxydecanoate-sensitive factors in signal channels transduction. Am J Physiol Cell Physiol 2010; 298: C875-892.
-
(2010)
Am J Physiol Cell Physiol
, vol.298
, pp. C875-C892
-
-
Chai, Y.1
Lin, Y.F.2
-
24
-
-
2942586992
-
Activity-dependent increase in beta-amyloid precursor protein mRNA expression in neurons
-
Tabuchi A, Ishii A, Fukuchi M, Kobayashi S, Suzuki T, Tsuda M. Activity-dependent increase in beta-amyloid precursor protein mRNA expression in neurons. Neuroreport 2004; 15: 1329-1333.
-
(2004)
Neuroreport
, vol.15
, pp. 1329-1333
-
-
Tabuchi, A.1
Ishii, A.2
Fukuchi, M.3
Kobayashi, S.4
Suzuki, T.5
Tsuda, M.6
-
25
-
-
34547102265
-
Roles of amyloid-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer’s disease and mild cognitive impairment
-
Butterfield DA, Reed T, Newman SF, Sultana R. Roles of amyloid-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer’s disease and mild cognitive impairment. Free Radic Biol Med 2007; 43: 658-677.
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 658-677
-
-
Butterfield, D.A.1
Reed, T.2
Newman, S.F.3
Sultana, R.4
-
26
-
-
67349253085
-
Oxidatively modified proteins in Alzheimer’s disease (AD), mild cognitive impairment and animal models of AD: Role of Abeta in pathogenesis
-
Sultana R, Perluigi M, Butterfield DA. Oxidatively modified proteins in Alzheimer’s disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis. Acta Neuropathol 2009; 118: 131-150.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 131-150
-
-
Sultana, R.1
Perluigi, M.2
Butterfield, D.A.3
-
27
-
-
0035875690
-
Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis
-
Pratico D, Uryu K, Leight S, Trojanoswki JQ, Lee VM. Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. J Neurosci 2001; 21: 4183-4187.
-
(2001)
J Neurosci
, vol.21
, pp. 4183-4187
-
-
Pratico, D.1
Uryu, K.2
Leight, S.3
Trojanoswki, J.Q.4
Lee, V.M.5
-
28
-
-
0036403838
-
Oxidative stress increases expression and activity of BACE in NT2 neurons
-
Tamagno E, Bardini P, Obbili A, Vitali A, Borghi R, Zaccheo D, Pronzato MA, Danni O, Smith MA, Perry G, Tabaton M. Oxidative stress increases expression and activity of BACE in NT2 neurons. Neurobiol Dis 2002; 10: 279-288.
-
(2002)
Neurobiol Dis
, vol.10
, pp. 279-288
-
-
Tamagno, E.1
Bardini, P.2
Obbili, A.3
Vitali, A.4
Borghi, R.5
Zaccheo, D.6
Pronzato, M.A.7
Danni, O.8
Smith, M.A.9
Perry, G.10
Tabaton, M.11
-
29
-
-
77951975308
-
SongW, Markesbery WR, Mattson MP. Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer’s disease
-
Jo DG, Arumugam TV, Woo HN, Park JS, Tang SC, Mughal M, Hyun DH, Park JH, Choi YH, Gwon AR, Camandola S, Cheng A, Cai H, SongW, Markesbery WR, Mattson MP. Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer’s disease. Neurobiol Aging 2010; 31: 917-925.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 917-925
-
-
Jo, D.G.1
Arumugam, T.V.2
Woo, H.N.3
Park, J.S.4
Tang, S.C.5
Mughal, M.6
Hyun, D.H.7
Park, J.H.8
Choi, Y.H.9
Gwon, A.R.10
Camandola, S.11
Cheng, A.12
Cai, H.13
-
30
-
-
0028200649
-
Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative
-
Gabuzda D, Busciglio J, Chen LB, Matsudaira P, Yankner BA. Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative. J Biol Chem 1994; 269: 13623-13628.
-
(1994)
J Biol Chem
, vol.269
, pp. 13623-13628
-
-
Gabuzda, D.1
Busciglio, J.2
Chen, L.B.3
Matsudaira, P.4
Yankner, B.A.5
-
31
-
-
20144386977
-
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer’s disease
-
Wang J, Ho L, Qin W, Rocher AB, Seror I, Humala N, Maniar K, Dolios G, Wang R, Hof PR, Pasinetti GM. Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer’s disease. FASEB J 2005; 19: 659-661.
-
(2005)
FASEB J
, vol.19
, pp. 659-661
-
-
Wang, J.1
Ho, L.2
Qin, W.3
Rocher, A.B.4
Seror, I.5
Humala, N.6
Maniar, K.7
Dolios, G.8
Wang, R.9
Hof, P.R.10
Pasinetti, G.M.11
-
32
-
-
33947264635
-
Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer’s disease
-
Halagappa VK, Guo Z, Pearson M, Matsuoka Y, Cutler RG, Laferla FM, Mattson MP. Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer’s disease. Neurobiol Dis 2007; 26: 212-220.
-
(2007)
Neurobiol Dis
, vol.26
, pp. 212-220
-
-
Halagappa, V.K.1
Guo, Z.2
Pearson, M.3
Matsuoka, Y.4
Cutler, R.G.5
Laferla, F.M.6
Mattson, M.P.7
-
33
-
-
70450246963
-
Depletion of vitamin
-
Nishida Y, Ito S, Ohtsuki S, Yamamoto N, Takahashi T, Iwata N, Jishage K, Yamada H, Sasaguri H, Yokota S, Piao W, Tomimitsu H, Saido TC, Yanagisawa K, Terasaki T, Mizusawa H, Yokota T. Depletion of vitamin E increases amyloid beta accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease. J Biol Chem 2009; 284: 33400-33408.
-
(2009)
E Increases Amyloid Beta Accumulation by Decreasing Its Clearances from Brain and Blood in a Mouse Model of Alzheimer Disease. J Biol Chem
, vol.284
, pp. 33400-33408
-
-
Nishida, Y.1
Ito, S.2
Ohtsuki, S.3
Yamamoto, N.4
Takahashi, T.5
Iwata, N.6
Jishage, K.7
Yamada, H.8
Sasaguri, H.9
Yokota, S.10
Piao, W.11
Tomimitsu, H.12
Saido, T.C.13
Yanagisawa, K.14
Terasaki, T.15
Mizusawa, H.16
Yokota, T.17
-
34
-
-
10744223843
-
Epigallocatechin gallate protects nerve growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase kinase-3
-
Koh SH, Kim SH, Kwon H, Park Y, Kim KS, Song CW, Kim J, Kim MH, Yu HJ, Henkel JS, Jung HK. Epigallocatechin gallate protects nerve growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase kinase-3. Brain Res Mol Brain Res 2003; 118: 72-81.
-
(2003)
Brain Res Mol Brain Res
, vol.118
, pp. 72-81
-
-
Koh, S.H.1
Kim, S.H.2
Kwon, H.3
Park, Y.4
Kim, K.S.5
Song, C.W.6
Kim, J.7
Kim, M.H.8
Yu, H.J.9
Henkel, J.S.10
Jung, H.K.11
-
35
-
-
1642471831
-
PI3K/Akt and apoptosis: Size matters
-
Franke TF, Hornik CP, Segev L, Shostak GA, Sugimoto C. PI3K/Akt and apoptosis: size matters. Oncogene 2003; 22: 8983-8998.
-
(2003)
Oncogene
, vol.22
, pp. 8983-8998
-
-
Franke, T.F.1
Hornik, C.P.2
Segev, L.3
Shostak, G.A.4
Sugimoto, C.5
-
36
-
-
81255135741
-
Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/BclXL-regulated mitochondrial apoptotic pathway
-
Zeng KW, Wang XM, Ko H, Kwon HC, Cha JW, Yang HO. Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/BclXL-regulated mitochondrial apoptotic pathway. Eur J Pharmacol 2011; 672: 45-55.
-
(2011)
Eur J Pharmacol
, vol.672
, pp. 45-55
-
-
Zeng, K.W.1
Wang, X.M.2
Ko, H.3
Kwon, H.C.4
Cha, J.W.5
Yang, H.O.6
-
37
-
-
79551543865
-
Implication of phosphatidylinositol-3 kinase/Akt/glycogen synthase kinase-3β pathway in ginsenoside Rb1’s attenuation of beta-amyloid-induced neurotoxicity and tau phosphorylation
-
Zhao R, Zhang Z, Song Y, Wang D, Qi J, Wen S. Implication of phosphatidylinositol-3 kinase/Akt/glycogen synthase kinase-3β pathway in ginsenoside Rb1’s attenuation of beta-amyloid-induced neurotoxicity and tau phosphorylation. J Ethnopharmaco 2011; 133: 1109-1116.
-
(2011)
J Ethnopharmaco
, vol.133
, pp. 1109-1116
-
-
Zhao, R.1
Zhang, Z.2
Song, Y.3
Wang, D.4
Qi, J.5
Wen, S.6
-
38
-
-
79959521714
-
Neuroprotective effects of linarin through activation of the PI3K/Akt pathway in amyloid-β-induced neuronal cell death
-
Lou H, Fan P, Perez RG, Lou H. Neuroprotective effects of linarin through activation of the PI3K/Akt pathway in amyloid-β-induced neuronal cell death. Bioorg Med Chem 2011; 19: 4021-4027.
-
(2011)
Bioorg Med Chem
, vol.19
, pp. 4021-4027
-
-
Lou, H.1
Fan, P.2
Perez, R.G.3
Lou, H.4
-
39
-
-
0035863188
-
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
-
Lucas JJ, Hernández F, Gómez-Ramos P, Morán MA, Hen R Avila J. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J 2001; 20: 27-39.
-
(2001)
EMBO J
, vol.20
, pp. 27-39
-
-
Lucas, J.J.1
Hernández, F.2
Gómez-Ramos, P.3
Morán, M.A.4
Hen R Avila, J.5
-
40
-
-
33646922314
-
Full reversal of Alzheimer’s disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3
-
Engel T, Hernández F, Avila J, Lucas, JJ. Full reversal of Alzheimer’s disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3. J Neurosci 2006; 26: 5083-5090.
-
(2006)
J Neurosci
, vol.26
, pp. 5083-5090
-
-
Engel, T.1
Hernández, F.2
Avila, J.3
Lucas, J.J.4
-
41
-
-
2642552331
-
Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing
-
Su Y, Ryder J, Li B, Wu X, Fox N, Solenberg P, Brune K, Paul S, Zhou Y, Liu F, Ni B. Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing. Biochemistry 2004; 43: 6899-6908.
-
(2004)
Biochemistry
, vol.43
, pp. 6899-6908
-
-
Su, Y.1
Ryder, J.2
Li, B.3
Wu, X.4
Fox, N.5
Solenberg, P.6
Brune, K.7
Paul, S.8
Zhou, Y.9
Liu, F.10
Ni, B.11
-
42
-
-
58149479354
-
GSK3 inhibitors show benefits in an Alzheimer’s disease (AD) model of neurodegeneration but adverse effects in control animals
-
Hu S, Begum AN, Jones MR, Oh MS, Beech WK, Beech BH, Yang F, Chen P, Ubeda OJ, Kim PC, Davies P, Ma Q, Cole GM, Frautschy SA. GSK3 inhibitors show benefits in an Alzheimer’s disease (AD) model of neurodegeneration but adverse effects in control animals. Neurobiol Dis 2009; 33: 193-206.
-
(2009)
Neurobiol Dis
, vol.33
, pp. 193-206
-
-
Hu, S.1
Begum, A.N.2
Jones, M.R.3
Oh, M.S.4
Beech, W.K.5
Beech, B.H.6
Yang, F.7
Chen, P.8
Ubeda, O.J.9
Kim, P.C.10
Davies, P.11
Ma, Q.12
Cole, G.M.13
Frautschy, S.A.14
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