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Volumn 34, Issue 7, 2015, Pages 955-973

PI3P binding by Atg21 organises Atg8 lipidation

Author keywords

autophagy; PROPPIN; ubiquitin like conjugation; WIPI

Indexed keywords

AUTOPHAGY PROTEIN 21; AUTOPHAGY PROTEIN 8; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PHOSPHOLIPID BINDING PROTEIN; UNCLASSIFIED DRUG; ATG21 PROTEIN, S CEREVISIAE; ATG3 PROTEIN, S CEREVISIAE; ATG8 PROTEIN, S CEREVISIAE; INOSITOL PHOSPHATE; MICROTUBULE ASSOCIATED PROTEIN; MULTIPROTEIN COMPLEX; PROTEIN BINDING; PROTEINASE; SACCHAROMYCES CEREVISIAE PROTEIN; UBIQUITIN CONJUGATING ENZYME;

EID: 84926253496     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201488957     Document Type: Article
Times cited : (70)

References (79)
  • 2
    • 33744830333 scopus 로고    scopus 로고
    • Two newly identified sites in the ubiquitin-like protein Atg8 are essential for autophagy
    • Amar N, Lustig G, Ichimura Y, Ohsumi Y, Elazar Z, (2006) Two newly identified sites in the ubiquitin-like protein Atg8 are essential for autophagy. EMBO Rep 7: 635-642
    • (2006) EMBO Rep , vol.7 , pp. 635-642
    • Amar, N.1    Lustig, G.2    Ichimura, Y.3    Ohsumi, Y.4    Elazar, Z.5
  • 3
    • 84866100323 scopus 로고    scopus 로고
    • Atg11: A Rab-dependent, coiled-coil membrane protein that acts as a tether for autophagy
    • Backues SK, Klionsky DJ, (2012) Atg11: a Rab-dependent, coiled-coil membrane protein that acts as a tether for autophagy. Autophagy 8: 1275-1278
    • (2012) Autophagy , vol.8 , pp. 1275-1278
    • Backues, S.K.1    Klionsky, D.J.2
  • 4
    • 84880547033 scopus 로고    scopus 로고
    • WIPI β-propellers in autophagy-related diseases and longevity
    • Bakula D, Takacs Z, Proikas-Cezanne T, (2013) WIPI β-propellers in autophagy-related diseases and longevity. Biochem Soc Trans 41: 962-967
    • (2013) Biochem Soc Trans , vol.41 , pp. 962-967
    • Bakula, D.1    Takacs, Z.2    Proikas-Cezanne, T.3
  • 5
    • 0035934225 scopus 로고    scopus 로고
    • A genomic screen identifies AUT8 as a novel gene essential for autophagy in the yeast Saccharomyces cerevisiae
    • Barth H, Thumm M, (2001) A genomic screen identifies AUT8 as a novel gene essential for autophagy in the yeast Saccharomyces cerevisiae. Gene 274: 151-156
    • (2001) Gene , vol.274 , pp. 151-156
    • Barth, H.1    Thumm, M.2
  • 6
    • 0037070221 scopus 로고    scopus 로고
    • Mai1p is essential for maturation of proaminopeptidase i but not for autophagy
    • Barth H, Meiling-Wesse K, Epple UD, Thumm M, (2002) Mai1p is essential for maturation of proaminopeptidase I but not for autophagy. FEBS Lett 512: 173-179
    • (2002) FEBS Lett , vol.512 , pp. 173-179
    • Barth, H.1    Meiling-Wesse, K.2    Epple, U.D.3    Thumm, M.4
  • 7
    • 84864960430 scopus 로고    scopus 로고
    • Two-site recognition of phosphatidylinositol 3-phosphate by PROPPINs in autophagy
    • Baskaran S, Ragusa MJ, Boura E, Hurley JH, (2012) Two-site recognition of phosphatidylinositol 3-phosphate by PROPPINs in autophagy. Mol Cell 47: 339-348
    • (2012) Mol Cell , vol.47 , pp. 339-348
    • Baskaran, S.1    Ragusa, M.J.2    Boura, E.3    Hurley, J.H.4
  • 8
    • 84877628647 scopus 로고    scopus 로고
    • Autophagy in human health and disease
    • Choi AMK, Ryter SW, Levine B, (2013) Autophagy in human health and disease. N Engl J Med 368: 651-662
    • (2013) N Engl J Med , vol.368 , pp. 651-662
    • Choi, A.M.K.1    Ryter, S.W.2    Levine, B.3
  • 9
    • 84904575441 scopus 로고    scopus 로고
    • WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1
    • Dooley HC, Razi M, Polson HEJ, Girardin SE, Wilson MI, Tooze SA, (2014) WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1. Mol Cell 55: 238-252
    • (2014) Mol Cell , vol.55 , pp. 238-252
    • Dooley, H.C.1    Razi, M.2    Polson, H.E.J.3    Girardin, S.E.4    Wilson, M.I.5    Tooze, S.A.6
  • 11
    • 35848929068 scopus 로고    scopus 로고
    • Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5-bisphosphate
    • Efe J, Botelho R, Emr S, (2007) Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5-bisphosphate. Mol Biol Cell 18: 4232-4244
    • (2007) Mol Biol Cell , vol.18 , pp. 4232-4244
    • Efe, J.1    Botelho, R.2    Emr, S.3
  • 13
    • 74049140368 scopus 로고    scopus 로고
    • Dimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy
    • Fujioka Y, Noda NN, Nakatogawa H, Ohsumi Y, Inagaki F, (2010) Dimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy. J Biol Chem 285: 1508-1515
    • (2010) J Biol Chem , vol.285 , pp. 1508-1515
    • Fujioka, Y.1    Noda, N.N.2    Nakatogawa, H.3    Ohsumi, Y.4    Inagaki, F.5
  • 14
    • 43949143804 scopus 로고    scopus 로고
    • The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
    • Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T, (2008) The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell 19: 2092-2100
    • (2008) Mol Biol Cell , vol.19 , pp. 2092-2100
    • Fujita, N.1    Itoh, T.2    Omori, H.3    Fukuda, M.4    Noda, T.5    Yoshimori, T.6
  • 15
    • 84884487128 scopus 로고    scopus 로고
    • ER exit sites are physical and functional core autophagosome biogenesis components
    • Graef M, Friedman JR, Graham C, Babu M, Nunnari J, (2013) ER exit sites are physical and functional core autophagosome biogenesis components. Mol Biol Cell 24: 2918-2931
    • (2013) Mol Biol Cell , vol.24 , pp. 2918-2931
    • Graef, M.1    Friedman, J.R.2    Graham, C.3    Babu, M.4    Nunnari, J.5
  • 17
    • 84883452831 scopus 로고    scopus 로고
    • Up-to-date membrane biogenesis in the autophagosome formation
    • Hamasaki M, Shibutani ST, Yoshimori T, (2013) Up-to-date membrane biogenesis in the autophagosome formation. Curr Opin Cell Biol 25: 455-460
    • (2013) Curr Opin Cell Biol , vol.25 , pp. 455-460
    • Hamasaki, M.1    Shibutani, S.T.2    Yoshimori, T.3
  • 19
    • 0029953575 scopus 로고    scopus 로고
    • Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway
    • Harding TM, Hefner-Gravink A, Thumm M, Klionsky DJ, (1996) Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway. J Biol Chem 271: 17621-17624
    • (1996) J Biol Chem , vol.271 , pp. 17621-17624
    • Harding, T.M.1    Hefner-Gravink, A.2    Thumm, M.3    Klionsky, D.J.4
  • 22
    • 84893500894 scopus 로고    scopus 로고
    • Molecular mechanism of autophagic membrane-scaffold assembly and disassembly
    • Kaufmann A, Beier V, Franquelim HG, Wollert T, (2014) Molecular mechanism of autophagic membrane-scaffold assembly and disassembly. Cell 156: 469-481
    • (2014) Cell , vol.156 , pp. 469-481
    • Kaufmann, A.1    Beier, V.2    Franquelim, H.G.3    Wollert, T.4
  • 23
    • 33746867157 scopus 로고    scopus 로고
    • The relevance of the phosphatidylinositolphosphat-binding motif FRRGT of Atg18 and Atg21 for the Cvt pathway and autophagy
    • Krick R, Tolstrup J, Appelles A, Henke S, Thumm M, (2006) The relevance of the phosphatidylinositolphosphat-binding motif FRRGT of Atg18 and Atg21 for the Cvt pathway and autophagy. FEBS Lett 580: 4632-4638
    • (2006) FEBS Lett , vol.580 , pp. 4632-4638
    • Krick, R.1    Tolstrup, J.2    Appelles, A.3    Henke, S.4    Thumm, M.5
  • 24
    • 53549091843 scopus 로고    scopus 로고
    • Dissecting the localization and function of Atg18, Atg21 and Ygr223c
    • Krick R, Henke S, Tolstrup J, Thumm M, (2008a) Dissecting the localization and function of Atg18, Atg21 and Ygr223c. Autophagy 4: 896-910
    • (2008) Autophagy , vol.4 , pp. 896-910
    • Krick, R.1    Henke, S.2    Tolstrup, J.3    Thumm, M.4
  • 27
    • 84864337089 scopus 로고    scopus 로고
    • Structural and functional characterization of the two phosphoinositide binding sites of PROPPINs, a β-propeller protein family
    • Krick R, Busse RA, Scacioc A, Stephan M, Janshoff A, Thumm M, Kühnel K, (2012) Structural and functional characterization of the two phosphoinositide binding sites of PROPPINs, a β-propeller protein family. Proc Natl Acad Sci USA 109: E2042-E2049
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. E2042-E2049
    • Krick, R.1    Busse, R.A.2    Scacioc, A.3    Stephan, M.4    Janshoff, A.5    Thumm, M.6    Kühnel, K.7
  • 28
    • 0032126632 scopus 로고    scopus 로고
    • Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole
    • Lang T, Schaeffeler E, Bernreuther D, Bredschneider M, Wolf DH, Thumm M, (1998) Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole. EMBO J 17: 3597-3607
    • (1998) EMBO J , vol.17 , pp. 3597-3607
    • Lang, T.1    Schaeffeler, E.2    Bernreuther, D.3    Bredschneider, M.4    Wolf, D.H.5    Thumm, M.6
  • 30
    • 0034610333 scopus 로고    scopus 로고
    • A new screen for protein interactions reveals that the Saccharomyces cerevisiae high mobility group proteins Nhp6A/B are involved in the regulation of the GAL1 promoter
    • Laser H, Bongards C, Schuller J, Heck S, Johnsson N, Lehming N, (2000) A new screen for protein interactions reveals that the Saccharomyces cerevisiae high mobility group proteins Nhp6A/B are involved in the regulation of the GAL1 promoter. Proc Natl Acad Sci USA 97: 13732-13737
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13732-13737
    • Laser, H.1    Bongards, C.2    Schuller, J.3    Heck, S.4    Johnsson, N.5    Lehming, N.6
  • 31
    • 38549092474 scopus 로고    scopus 로고
    • Membrane recognition by phospholipid-binding domains
    • Lemmon MA, (2008) Membrane recognition by phospholipid-binding domains. Nat Rev Mol Cell Biol 9: 99-111
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 99-111
    • Lemmon, M.A.1
  • 32
    • 77957198526 scopus 로고    scopus 로고
    • An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis
    • Mari M, Griffith J, Rieter E, Krishnappa L, Klionsky DJ, Reggiori F, (2010) An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis. J Cell Biol 190: 1005-1022
    • (2010) J Cell Biol , vol.190 , pp. 1005-1022
    • Mari, M.1    Griffith, J.2    Rieter, E.3    Krishnappa, L.4    Klionsky, D.J.5    Reggiori, F.6
  • 33
    • 4444260908 scopus 로고    scopus 로고
    • Atg21 is required for effective recruitment of Atg8 to the preautophagosomal structure during the Cvt pathway
    • Meiling-Wesse K, Barth H, Voss C, Eskelinen E-L, Epple UD, Thumm M, (2004) Atg21 is required for effective recruitment of Atg8 to the preautophagosomal structure during the Cvt pathway. J Biol Chem 279: 37741-37750
    • (2004) J Biol Chem , vol.279 , pp. 37741-37750
    • Meiling-Wesse, K.1    Barth, H.2    Voss, C.3    Eskelinen, E.-L.4    Epple, U.D.5    Thumm, M.6
  • 34
    • 25844489089 scopus 로고    scopus 로고
    • Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway
    • Meiling-Wesse K, Epple UD, Krick R, Barth H, Appelles A, Voss C, Eskelinen E-L, Thumm M, (2005) Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. J Biol Chem 280: 33669-33678
    • (2005) J Biol Chem , vol.280 , pp. 33669-33678
    • Meiling-Wesse, K.1    Epple, U.D.2    Krick, R.3    Barth, H.4    Appelles, A.5    Voss, C.6    Eskelinen, E.-L.7    Thumm, M.8
  • 35
    • 84888096050 scopus 로고    scopus 로고
    • Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12
    • Metlagel Z, Otomo C, Takaesu G, Otomo T, (2013) Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12. Proc Natl Acad Sci USA 110: 18844-18849
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 18844-18849
    • Metlagel, Z.1    Otomo, C.2    Takaesu, G.3    Otomo, T.4
  • 36
    • 0033565655 scopus 로고    scopus 로고
    • Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway
    • Mizushima N, Noda T, Ohsumi Y, (1999) Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway. EMBO J 18: 3888-3896
    • (1999) EMBO J , vol.18 , pp. 3888-3896
    • Mizushima, N.1    Noda, T.2    Ohsumi, Y.3
  • 38
    • 84855807389 scopus 로고    scopus 로고
    • Conditional peripheral membrane proteins: Facing up to limited specificity
    • Moravcevic K, Oxley CL, Lemmon MA, (2012) Conditional peripheral membrane proteins: facing up to limited specificity. Structure 20: 15-27
    • (2012) Structure , vol.20 , pp. 15-27
    • Moravcevic, K.1    Oxley, C.L.2    Lemmon, M.A.3
  • 39
    • 54349115675 scopus 로고    scopus 로고
    • Split-ubiquitin and the split-protein sensors: Chessman for the endgame
    • Müller J, Johnsson N, (2008) Split-ubiquitin and the split-protein sensors: chessman for the endgame. ChemBioChem 9: 2029-2038
    • (2008) ChemBioChem , vol.9 , pp. 2029-2038
    • Müller, J.1    Johnsson, N.2
  • 40
    • 77951215334 scopus 로고    scopus 로고
    • Roles of the lipid-binding motifs of Atg18 and Atg21 in the cytoplasm to vacuole targeting pathway and autophagy
    • Nair U, Cao Y, Xie Z, Klionsky DJ, (2010) Roles of the lipid-binding motifs of Atg18 and Atg21 in the cytoplasm to vacuole targeting pathway and autophagy. J Biol Chem 285: 11476-11488
    • (2010) J Biol Chem , vol.285 , pp. 11476-11488
    • Nair, U.1    Cao, Y.2    Xie, Z.3    Klionsky, D.J.4
  • 42
    • 34447099450 scopus 로고    scopus 로고
    • Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion
    • Nakatogawa H, Ichimura Y, Ohsumi Y, (2007) Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion. Cell 130: 165-178
    • (2007) Cell , vol.130 , pp. 165-178
    • Nakatogawa, H.1    Ichimura, Y.2    Ohsumi, Y.3
  • 44
    • 0029953712 scopus 로고    scopus 로고
    • Green fluorescent protein as a marker for gene expression and subcellular localization in budding yeast
    • Niedenthal R, Riles L, Johnston M, Hegemann J, (1996) Green fluorescent protein as a marker for gene expression and subcellular localization in budding yeast. Yeast 12: 773-786
    • (1996) Yeast , vol.12 , pp. 773-786
    • Niedenthal, R.1    Riles, L.2    Johnston, M.3    Hegemann, J.4
  • 46
    • 77950484269 scopus 로고    scopus 로고
    • Atg8-family interacting motif crucial for selective autophagy
    • Noda NN, Ohsumi Y, Inagaki F, (2010) Atg8-family interacting motif crucial for selective autophagy. FEBS Lett 584: 1379-1385
    • (2010) FEBS Lett , vol.584 , pp. 1379-1385
    • Noda, N.N.1    Ohsumi, Y.2    Inagaki, F.3
  • 47
    • 84873405258 scopus 로고    scopus 로고
    • Structure of the Atg12-Atg5 conjugate reveals a platform for stimulating Atg8-PE conjugation
    • Noda NN, Fujioka Y, Hanada T, Ohsumi Y, Inagaki F, (2013) Structure of the Atg12-Atg5 conjugate reveals a platform for stimulating Atg8-PE conjugation. EMBO Rep 14: 206-211
    • (2013) EMBO Rep , vol.14 , pp. 206-211
    • Noda, N.N.1    Fujioka, Y.2    Hanada, T.3    Ohsumi, Y.4    Inagaki, F.5
  • 48
    • 53049102656 scopus 로고    scopus 로고
    • The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function
    • Obara K, Sekito T, Niimi K, Ohsumi Y, (2008) The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function. J Biol Chem 283: 23972-23980
    • (2008) J Biol Chem , vol.283 , pp. 23972-23980
    • Obara, K.1    Sekito, T.2    Niimi, K.3    Ohsumi, Y.4
  • 49
    • 84855315431 scopus 로고    scopus 로고
    • Atg14: A key player in orchestrating autophagy
    • Obara K, Ohsumi Y, (2011) Atg14: a key player in orchestrating autophagy. Int J Cell Biol 2011: 713435
    • (2011) Int J Cell Biol , vol.2011 , pp. 713435
    • Obara, K.1    Ohsumi, Y.2
  • 50
    • 78149456945 scopus 로고    scopus 로고
    • WD40 repeat propellers define a ubiquitin-binding domain that regulates turnover of F box proteins
    • Pashkova N, Gakhar L, Winistorfer SC, Yu L, Ramaswamy S, Piper RC, (2010) WD40 repeat propellers define a ubiquitin-binding domain that regulates turnover of F box proteins. Mol Cell 40: 433-443
    • (2010) Mol Cell , vol.40 , pp. 433-443
    • Pashkova, N.1    Gakhar, L.2    Winistorfer, S.C.3    Yu, L.4    Ramaswamy, S.5    Piper, R.C.6
  • 51
    • 77953726483 scopus 로고    scopus 로고
    • Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation
    • Polson HEJ, De Lartigue J, Rigden DJ, Reedijk M, Urbé S, Clague MJ, Tooze SA, (2010) Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation. Autophagy 6: 506-522
    • (2010) Autophagy , vol.6 , pp. 506-522
    • Polson, H.E.J.1    De Lartigue, J.2    Rigden, D.J.3    Reedijk, M.4    Urbé, S.5    Clague, M.J.6    Tooze, S.A.7
  • 52
    • 0346503885 scopus 로고    scopus 로고
    • The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure
    • Reggiori F, Tucker K, Stromhaug P, Klionsky D, (2004) The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev Cell 6: 79-90
    • (2004) Dev Cell , vol.6 , pp. 79-90
    • Reggiori, F.1    Tucker, K.2    Stromhaug, P.3    Klionsky, D.4
  • 53
    • 84878562770 scopus 로고    scopus 로고
    • Autophagic processes in yeast: Mechanism, machinery and regulation
    • Reggiori F, Klionsky DJ, (2013) Autophagic processes in yeast: mechanism, machinery and regulation. Genetics 194: 341-361
    • (2013) Genetics , vol.194 , pp. 341-361
    • Reggiori, F.1    Klionsky, D.J.2
  • 55
    • 84869210001 scopus 로고    scopus 로고
    • Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation
    • Romanov J, Walczak M, Ibiricu I, Schüchner S, Ogris E, Kraft C, Martens S, (2012) Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation. EMBO J 31: 4304-4317
    • (2012) EMBO J , vol.31 , pp. 4304-4317
    • Romanov, J.1    Walczak, M.2    Ibiricu, I.3    Schüchner, S.4    Ogris, E.5    Kraft, C.6    Martens, S.7
  • 60
    • 77951977288 scopus 로고    scopus 로고
    • Solution structure of Atg8 reveals conformational polymorphism of the N-terminal domain
    • Schwarten M, Stoldt M, Mohrlüder J, Willbold D, (2010) Solution structure of Atg8 reveals conformational polymorphism of the N-terminal domain. Biochem Biophys Res Commun 395: 426-431
    • (2010) Biochem Biophys Res Commun , vol.395 , pp. 426-431
    • Schwarten, M.1    Stoldt, M.2    Mohrlüder, J.3    Willbold, D.4
  • 63
    • 0031008471 scopus 로고    scopus 로고
    • AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae
    • Straub M, Bredschneider M, Thumm M, (1997) AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae. J Bacteriol 179: 3875-3883
    • (1997) J Bacteriol , vol.179 , pp. 3875-3883
    • Straub, M.1    Bredschneider, M.2    Thumm, M.3
  • 64
    • 3342951135 scopus 로고    scopus 로고
    • Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase i by selective autophagy
    • Stromhaug P, Reggiori F, Guan J, Wang C, Klionsky D, (2004) Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy. Mol Biol Cell 15: 3553-3566
    • (2004) Mol Biol Cell , vol.15 , pp. 3553-3566
    • Stromhaug, P.1    Reggiori, F.2    Guan, J.3    Wang, C.4    Klionsky, D.5
  • 65
    • 0035503594 scopus 로고    scopus 로고
    • The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
    • Suzuki K, Kirisako T, Kamada Y, Mizushima N, Noda T, Ohsumi Y, (2001) The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J 20: 5971-5981
    • (2001) EMBO J , vol.20 , pp. 5971-5981
    • Suzuki, K.1    Kirisako, T.2    Kamada, Y.3    Mizushima, N.4    Noda, T.5    Ohsumi, Y.6
  • 66
    • 33846514235 scopus 로고    scopus 로고
    • Hierarchy of Atg proteins in pre-autophagosomal structure organization
    • Suzuki K, Kubota Y, Sekito T, Ohsumi Y, (2007) Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 12: 209-218
    • (2007) Genes Cells , vol.12 , pp. 209-218
    • Suzuki, K.1    Kubota, Y.2    Sekito, T.3    Ohsumi, Y.4
  • 67
    • 84880019176 scopus 로고    scopus 로고
    • Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae
    • Suzuki K, Akioka M, Kondo-Kakuta C, Yamamoto H, Ohsumi Y, (2013) Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae. J Cell Sci 126: 2534-2544
    • (2013) J Cell Sci , vol.126 , pp. 2534-2544
    • Suzuki, K.1    Akioka, M.2    Kondo-Kakuta, C.3    Yamamoto, H.4    Ohsumi, Y.5
  • 68
    • 84884239840 scopus 로고    scopus 로고
    • Atg18 phosphoregulation controls organellar dynamics by modulating its phosphoinositide-binding activity
    • Tamura N, Oku M, Ito M, Noda NN, Inagaki F, Sakai Y, (2013) Atg18 phosphoregulation controls organellar dynamics by modulating its phosphoinositide-binding activity. J Cell Biol 202: 685-698
    • (2013) J Cell Biol , vol.202 , pp. 685-698
    • Tamura, N.1    Oku, M.2    Ito, M.3    Noda, N.N.4    Inagaki, F.5    Sakai, Y.6
  • 72
    • 77953122645 scopus 로고    scopus 로고
    • LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis
    • Weidberg H, Shvets E, Shpilka T, Shimron F, Shinder V, Elazar Z, (2010) LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis. EMBO J 29: 1792-1802
    • (2010) EMBO J , vol.29 , pp. 1792-1802
    • Weidberg, H.1    Shvets, E.2    Shpilka, T.3    Shimron, F.4    Shinder, V.5    Elazar, Z.6
  • 73
    • 79954544250 scopus 로고    scopus 로고
    • LC3 and GATE-16 N termini mediate membrane fusion processes required for autophagosome biogenesis
    • Weidberg H, Shpilka T, Shvets E, Abada A, Shimron F, Elazar Z, (2011) LC3 and GATE-16 N termini mediate membrane fusion processes required for autophagosome biogenesis. Dev Cell 20: 444-454
    • (2011) Dev Cell , vol.20 , pp. 444-454
    • Weidberg, H.1    Shpilka, T.2    Shvets, E.3    Abada, A.4    Shimron, F.5    Elazar, Z.6
  • 74
    • 84885327315 scopus 로고    scopus 로고
    • Uth1 is a mitochondrial inner membrane protein dispensable for post-log-phase and rapamycin-induced mitophagy
    • Welter E, Montino M, Reinhold R, Schlotterhose P, Krick R, Dudek J, Rehling P, Thumm M, (2013) Uth1 is a mitochondrial inner membrane protein dispensable for post-log-phase and rapamycin-induced mitophagy. FEBS J 280: 4970-4982
    • (2013) FEBS J , vol.280 , pp. 4970-4982
    • Welter, E.1    Montino, M.2    Reinhold, R.3    Schlotterhose, P.4    Krick, R.5    Dudek, J.6    Rehling, P.7    Thumm, M.8
  • 75
    • 0032803068 scopus 로고    scopus 로고
    • Probing the molecular environment of membrane proteins in vivo
    • Wittke S, Lewke N, Muller S, Johnsson N, (1999) Probing the molecular environment of membrane proteins in vivo. Mol Biol Cell 10: 2519-2530
    • (1999) Mol Biol Cell , vol.10 , pp. 2519-2530
    • Wittke, S.1    Lewke, N.2    Muller, S.3    Johnsson, N.4
  • 76
    • 47549092694 scopus 로고    scopus 로고
    • Atg8 controls phagophore expansion during autophagosome formation
    • Xie Z, Nair U, Klionsky DJ, (2008) Atg8 controls phagophore expansion during autophagosome formation. Mol Biol Cell 19: 3290-3298
    • (2008) Mol Biol Cell , vol.19 , pp. 3290-3298
    • Xie, Z.1    Nair, U.2    Klionsky, D.J.3
  • 77
    • 77956499358 scopus 로고    scopus 로고
    • Autophagy-related protein 8 (Atg8) family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway
    • Yamaguchi M, Noda NN, Nakatogawa H, Kumeta H, Ohsumi Y, Inagaki F, (2010) Autophagy-related protein 8 (Atg8) family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway. J Biol Chem 285: 29599-29607
    • (2010) J Biol Chem , vol.285 , pp. 29599-29607
    • Yamaguchi, M.1    Noda, N.N.2    Nakatogawa, H.3    Kumeta, H.4    Ohsumi, Y.5    Inagaki, F.6
  • 79
    • 84878897444 scopus 로고    scopus 로고
    • Biology and trafficking of ATG9 and ATG16L1, two proteins that regulate autophagosome formation
    • Zavodszky E, Vicinanza M, Rubinsztein DC, (2013) Biology and trafficking of ATG9 and ATG16L1, two proteins that regulate autophagosome formation. FEBS Lett 587: 1988-1996
    • (2013) FEBS Lett , vol.587 , pp. 1988-1996
    • Zavodszky, E.1    Vicinanza, M.2    Rubinsztein, D.C.3


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