Structural and functional characterization of the two phosphoinositide binding sites of PROPPINs, a β-propeller protein family

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 30, 2012, Pages

  Krick, Roswitha ^a   Busse, Ricarda A ^b   Scacioc, Andreea ^b   Stephan, Milena ^a   Janshoff, Andreas ^a   Thumm, Michael ^a   Kühnel, Karin ^b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Autophagy; Protein lipid interactions; X ray crystallography; Yeast

Indexed keywords

BETA PROPELLER PROTEIN THAT BIND POLYPHOSPHOINOSITIDE; LIPOSOME; MUTANT PROTEIN; PHOSPHATIDYLINOSITIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL MEMBRANE; COMPUTER MODEL; CRYSTAL STRUCTURE; FLUORESCENCE MICROSCOPY; FUNGAL CELL; ISOTHERMAL TITRATION CALORIMETRY; KLUYVEROMYCES LACTIS; MACROAUTOPHAGY; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN LIPID INTERACTION; PROTEIN MOTIF; PROTEIN STRUCTURE; REFLECTOMETRY; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; BINDING SITES; CLONING, MOLECULAR; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; KLUYVEROMYCES; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS; PHOSPHATIDYLINOSITOLS; PROTEIN BINDING; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA; KLUYVEROMYCES LACTIS; SACCHAROMYCES CEREVISIAE;

EID: 84864337089     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1205128109     Document Type: Article

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