Elucidating molecular phenotypes caused by the SORL1 Alzheimer's disease genetic risk factor using human induced pluripotent stem cells

Cell Stem Cell

Volumn 16, Issue 4, 2015, Pages 373-385

  Young, Jessica E ^a   Boulanger Weill, Jonathan ^a   Williams, Daniel A ^a   Woodruff, Grace ^a   Buen, Floyd ^a   Revilla, Arra C ^a   Herrera, Cheryl ^a   Israel, Mason A ^a   Yuan, Shauna H ^b   Edland, Steven D ^b,c   Goldstein, Lawrence S B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; COMPLEMENTARY DNA; CYCLIC AMP; NEUROTROPHIC FACTOR; SHORT HAIRPIN RNA; BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN; CARRIER PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; SERUM AMYLOID A; SMALL INTERFERING RNA; SORL1 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ARTICLE; GENE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; NERVE CELL; NEURAL STEM CELL; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SORL1 GENE; SPORADIC ALZHEIMER DISEASE; CELL LINE; DNA MUTATIONAL ANALYSIS; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; INDUCED PLURIPOTENT STEM CELL; METABOLISM; PHYSIOLOGY; PROCEDURES; PROTEIN TRANSPORT; RISK FACTOR;

ALZHEIMER DISEASE; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL LINE; DNA MUTATIONAL ANALYSIS; GENE EXPRESSION REGULATION; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LDL-RECEPTOR RELATED PROTEINS; MEMBRANE TRANSPORT PROTEINS; NEURONS; PHENOTYPE; POLYMORPHISM, GENETIC; PROTEIN TRANSPORT; RISK FACTORS; RNA, SMALL INTERFERING; SERUM AMYLOID A PROTEIN;

EID: 84926222043     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2015.02.004     Document Type: Article

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