-
2
-
-
1542376929
-
Glutathione metabolism and its implications for health
-
Wu G, Fang YZ, Yang S, Lupton JR, Turner ND. Glutathione metabolism and its implications for health. J Nutr 2004; 134: 489-492
-
(2004)
J Nutr
, vol.134
, pp. 489-492
-
-
Wu, G.1
Fang, Y.Z.2
Yang, S.3
Lupton, J.R.4
Turner, N.D.5
-
3
-
-
84864317126
-
Reactive oxygen and nitrogen species generation, antioxidant defenses, and β-cell function: A critical role for amino acids
-
Newsholme P, Rebelato E, Abdulkader F, Krause M, Carpinelli A, Curi R., et al. Reactive oxygen and nitrogen species generation, antioxidant defenses, and β-cell function: a critical role for amino acids. J Endocrinol 2012; 214: 11-20
-
(2012)
J Endocrinol
, vol.214
, pp. 11-20
-
-
Newsholme, P.1
Rebelato, E.2
Abdulkader, F.3
Krause, M.4
Carpinelli, A.5
Curi, R.6
-
4
-
-
84872401746
-
Nutritional regulation of insulin secretion: Implications for diabetes
-
Newsholme P, Krause M. Nutritional regulation of insulin secretion: implications for diabetes. Clin Biochem Rev 2012; 33: 35-47
-
(2012)
Clin Biochem Rev
, vol.33
, pp. 35-47
-
-
Newsholme, P.1
Krause, M.2
-
6
-
-
79951696287
-
Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine
-
Sekhar RV, McKay SV, Patel SG. Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine. Diabetes Care 2011; 34: 162-167
-
(2011)
Diabetes Care
, vol.34
, pp. 162-167
-
-
Sekhar, R.V.1
McKay, S.V.2
Patel, S.G.3
-
7
-
-
56649092631
-
Poorly controlled type 1 diabetes is associated with altered glutathione homeostasis in adolescents: Apparent resistance to N-Acetylcysteine supplementation
-
Darmaun D, Smith SD, Sweeten S, Hartman BK, Welch C, Mauras N., et al. Poorly controlled type 1 diabetes is associated with altered glutathione homeostasis in adolescents: apparent resistance to N-Acetylcysteine supplementation. Pediatr Diabetes 2008; 9: 577-582
-
(2008)
Pediatr Diabetes
, vol.9
, pp. 577-582
-
-
Darmaun, D.1
Smith, S.D.2
Sweeten, S.3
Hartman, B.K.4
Welch, C.5
Mauras, N.6
-
8
-
-
0028273785
-
Effect of glycemic control, race (white versus black), and duration of diabetes on reduced glutathione content in erythrocytes of diabetic patients
-
Jain SK, McVie R. Effect of glycemic control, race (white versus black), and duration of diabetes on reduced glutathione content in erythrocytes of diabetic patients. Metabolism 1994; 43: 306-309
-
(1994)
Metabolism
, vol.43
, pp. 306-309
-
-
Jain, S.K.1
McVie, R.2
-
9
-
-
12144274310
-
Evidence for accelerated rates of glutathione utilization and glutathione depletion in adolescents with poorly controlled type 1 diabetes
-
Darmaun D, Smith SD, Sweeten S, Sager BK, Welch S, Mauras N., et al. Evidence for accelerated rates of glutathione utilization and glutathione depletion in adolescents with poorly controlled type 1 diabetes. Diabetes 2005; 54: 190-196
-
(2005)
Diabetes
, vol.54
, pp. 190-196
-
-
Darmaun, D.1
Smith, S.D.2
Sweeten, S.3
Sager, B.K.4
Welch, S.5
Mauras, N.6
-
10
-
-
80052600114
-
Vitamin D and type 2 diabetes: A systematic review
-
Mitri J, Muraru MD, Pittas AG. Vitamin D and type 2 diabetes: a systematic review. Eur J Clin Nutr 2011; 65: 1005-1015
-
(2011)
Eur J Clin Nutr
, vol.65
, pp. 1005-1015
-
-
Mitri, J.1
Muraru, M.D.2
Pittas, A.G.3
-
11
-
-
84866146531
-
The nonskeletal effects of vitamin D: An endocrine society scientific statement
-
Rosen CJ, Adams JS, Bikle DD, Black DM, Demay MB, Manson JE., et al. The nonskeletal effects of vitamin D: an endocrine society scientific statement. Endocr Rev 2012; 33: 456-492
-
(2012)
Endocr Rev
, vol.33
, pp. 456-492
-
-
Rosen, C.J.1
Adams, J.S.2
Bikle, D.D.3
Black, D.M.4
Demay, M.B.5
Manson, J.E.6
-
12
-
-
80052580056
-
An estimate of the global reduction in mortality rates through doubling vitamin D levels
-
Grant WB. An estimate of the global reduction in mortality rates through doubling vitamin D levels. Eur J Clin Nutr 2011; 65: 1016-1026
-
(2011)
Eur J Clin Nutr
, vol.65
, pp. 1016-1026
-
-
Grant, W.B.1
-
13
-
-
0036305669
-
Hyperketonemia increases TNF-α secretion in cultured U937 monocytes and type-1 diabetic patients and is apparently mediated by oxidative stress and cAMP-deficiency
-
Jain SK, Kannan K, Lim G, McVie R, Bocchini JA. Hyperketonemia increases TNF-α secretion in cultured U937 monocytes and type-1 diabetic patients and is apparently mediated by oxidative stress and cAMP-deficiency. Diabetes 2002; 51: 2287-2293
-
(2002)
Diabetes
, vol.51
, pp. 2287-2293
-
-
Jain, S.K.1
Kannan, K.2
Lim, G.3
McVie, R.4
Bocchini, J.A.5
-
14
-
-
0032992889
-
Rapid and accurate HPLC assay for plasma total homocysteine and cysteine in a clinical laboratory setting
-
Pfeiffer CM, Huff DL, Gunter EW. Rapid and accurate HPLC assay for plasma total homocysteine and cysteine in a clinical laboratory setting. Clin Chem 1999; 45: 290-292
-
(1999)
Clin Chem
, vol.45
, pp. 290-292
-
-
Pfeiffer, C.M.1
Huff, D.L.2
Gunter, E.W.3
-
15
-
-
84869184860
-
The effect of sleep apnea and insomnia on blood levels of leptin, insulin resistance, IP-10, and hydrogen sulfide in type 2 diabetic patients
-
Jain SK, Kahlon G, Morehead L, Lieblong B, Stapleton T, Hoeldtke R., et al. The effect of sleep apnea and insomnia on blood levels of leptin, insulin resistance, IP-10, and hydrogen sulfide in type 2 diabetic patients. Metab Syndr Relat Disord 2012; 10: 331-336
-
(2012)
Metab Syndr Relat Disord
, vol.10
, pp. 331-336
-
-
Jain, S.K.1
Kahlon, G.2
Morehead, L.3
Lieblong, B.4
Stapleton, T.5
Hoeldtke, R.6
-
16
-
-
0021356863
-
Vitamin e deficiency with normal serum vitamin e concentrations in children with chronic cholestasis
-
Sokol RJ, Heubi JE, Iannaccone ST, Bove KE, Balistreri WF. Vitamin E deficiency with normal serum vitamin E concentrations in children with chronic cholestasis. N Engl J Med 1984; 310: 1209-1212
-
(1984)
N Engl J Med
, vol.310
, pp. 1209-1212
-
-
Sokol, R.J.1
Heubi, J.E.2
Iannaccone, S.T.3
Bove, K.E.4
Balistreri, W.F.5
-
17
-
-
65049090510
-
Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase
-
Franklin CC, Backos DS, Mohar I, White CC, Forman HJ, Kavanagh TJ., et al. Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase. Mol Aspects of Med 2009; 30: 86-98
-
(2009)
Mol Aspects of Med
, vol.30
, pp. 86-98
-
-
Franklin, C.C.1
Backos, D.S.2
Mohar, I.3
White, C.C.4
Forman, H.J.5
Kavanagh, T.J.6
-
18
-
-
84880513183
-
Vitamin D upregulates glutamate cysteine ligase and glutathione reductase, and GSH formation, and decreases ROS and MCP-1 and IL-8 secretion in high-glucose exposed U-937 monocytes
-
Jain SK, Micinski D. Vitamin D upregulates glutamate cysteine ligase and glutathione reductase, and GSH formation, and decreases ROS and MCP-1 and IL-8 secretion in high-glucose exposed U-937 monocytes. Biochem Biophys Res Commun 2013; 437: 7-11
-
(2013)
Biochem Biophys Res Commun
, vol.437
, pp. 7-11
-
-
Jain, S.K.1
Micinski, D.2
-
19
-
-
0024803840
-
Hyperglycemia can cause membrane lipid peroxidation and osmotic fragility in human red blood cells
-
Jain SK. Hyperglycemia can cause membrane lipid peroxidation and osmotic fragility in human red blood cells. J Biol Chem 1989; 264: 21340-21345
-
(1989)
J Biol Chem
, vol.264
, pp. 21340-21345
-
-
Jain, S.K.1
-
20
-
-
0024408737
-
Erythrocyte membrane lipid peroxidation and glycosylated hemoglobin in diabetes
-
Jain SK, McVie R, Duett J, Herbst JJ. Erythrocyte membrane lipid peroxidation and glycosylated hemoglobin in diabetes. Diabetes 1989; 38: 1539-1543
-
(1989)
Diabetes
, vol.38
, pp. 1539-1543
-
-
Jain, S.K.1
McVie, R.2
Duett, J.3
Herbst, J.J.4
-
21
-
-
79551470306
-
Oxidative stress, insulin signaling, and diabetes
-
Rains JL, Jain SK. Oxidative stress, insulin signaling, and diabetes. Free Radic Biol Med 2011; 50: 567-575
-
(2011)
Free Radic Biol Med
, vol.50
, pp. 567-575
-
-
Rains, J.L.1
Jain, S.K.2
-
22
-
-
84867871977
-
Differential nitric oxide levels in the blood and skeletal muscle of type 2 diabetic subjects may be consequence of adiposity: A preliminary study
-
Krause M, Rodrigues-Krause J, O'Hagan C, De Vito G, Boreham C, Susta D., et al. Differential nitric oxide levels in the blood and skeletal muscle of type 2 diabetic subjects may be consequence of adiposity: a preliminary study. Metabolism 2012; 61: 1528-1537
-
(2012)
Metabolism
, vol.61
, pp. 1528-1537
-
-
Krause, M.1
Rodrigues-Krause, J.2
O'Hagan, C.3
De Vito, G.4
Boreham, C.5
Susta, D.6
-
23
-
-
84885771953
-
Chlorogenic acid, a dietary polyphenol, protects acetaminophen-induced liver injury and its mechanism
-
Ji L, Jiang P, Lu B, Sheng Y, Wang X, Wang Z., et al. Chlorogenic acid, a dietary polyphenol, protects acetaminophen-induced liver injury and its mechanism. J Nutr Biochem 2013; 24: 1911-1919
-
(2013)
J Nutr Biochem
, vol.24
, pp. 1911-1919
-
-
Ji, L.1
Jiang, P.2
Lu, B.3
Sheng, Y.4
Wang, X.5
Wang, Z.6
-
24
-
-
67349179553
-
L-cysteine supplementation lowers blood glucose, glycated hemoglobin, CRP, MCP-1, oxidative stress and inhibits NFkB activation in the livers of Zucker diabetic rats
-
Jain SK, Velusamy T, Croad JL, Rains JL, Bull R. L-cysteine supplementation lowers blood glucose, glycated hemoglobin, CRP, MCP-1, oxidative stress and inhibits NFkB activation in the livers of Zucker diabetic rats. Free Radic Biol Med 2009; 46: 1633-1638
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 1633-1638
-
-
Jain, S.K.1
Velusamy, T.2
Croad, J.L.3
Rains, J.L.4
Bull, R.5
-
25
-
-
84884842381
-
Dairy products and the risk of type 2 diabetes: A systematic review and dose-response meta-Analysis of cohort studies
-
Aune D, Norat T, Romundstad P, Vatten L. Dairy products and the risk of type 2 diabetes: a systematic review and dose-response meta-Analysis of cohort studies. Am J Clin Nutr 2013; 98: 1066-1083
-
(2013)
Am J Clin Nutr
, vol.98
, pp. 1066-1083
-
-
Aune, D.1
Norat, T.2
Romundstad, P.3
Vatten, L.4
-
26
-
-
33746214587
-
Effects of N-Acetylcysteine on sucrose-rich diet-induced hyperglycaemia, dyslipidemia and oxidative stress in rats
-
Diniz YS, Rocha KK, Souza GA, Galhardi CM, Ebaid GM, Rodrigues HG., et al. Effects of N-Acetylcysteine on sucrose-rich diet-induced hyperglycaemia, dyslipidemia and oxidative stress in rats. Eur J Pharmacol 2006; 543: 151-157
-
(2006)
Eur J Pharmacol
, vol.543
, pp. 151-157
-
-
Diniz, Y.S.1
Rocha, K.K.2
Souza, G.A.3
Galhardi, C.M.4
Ebaid, G.M.5
Rodrigues, H.G.6
-
27
-
-
84879486166
-
A whey protein hydrolysate promotes insulinotropic activity in a clonal pancreatic β-cell line and enhances glycemic function in ob/ob mice
-
Gaudel C, Nongonierma AB, Maher S, Flynn S, Krause M, Murray BA., et al. A whey protein hydrolysate promotes insulinotropic activity in a clonal pancreatic β-cell line and enhances glycemic function in ob/ob mice. J Nutr 2013; 143: 1109-1114
-
(2013)
J Nutr
, vol.143
, pp. 1109-1114
-
-
Gaudel, C.1
Nongonierma, A.B.2
Maher, S.3
Flynn, S.4
Krause, M.5
Murray, B.A.6
-
28
-
-
79955505073
-
Dietary whey protein lowers the risk for metabolic disease in mice fed a high-fat diet
-
Shertzer HG, Woods SE, Krishan M, Genter MB, Pearson KJ. Dietary whey protein lowers the risk for metabolic disease in mice fed a high-fat diet. J Nutr 2011; 141: 582-587
-
(2011)
J Nutr
, vol.141
, pp. 582-587
-
-
Shertzer, H.G.1
Woods, S.E.2
Krishan, M.3
Genter, M.B.4
Pearson, K.J.5
-
29
-
-
41949085081
-
The antidiabetic effects of cysteinyl metformin, a newly synthesized agent, in alloxan- and streptozocin-induced diabetic rats
-
Liu Z, Li J, Zeng Z, Liu M, Wang M. The antidiabetic effects of cysteinyl metformin, a newly synthesized agent, in alloxan- and streptozocin-induced diabetic rats. Chem Biol Interact 2008; 173: 68-75
-
(2008)
Chem Biol Interact
, vol.173
, pp. 68-75
-
-
Liu, Z.1
Li, J.2
Zeng, Z.3
Liu, M.4
Wang, M.5
-
30
-
-
0031800116
-
Oral administration of the antioxidant, N-Acetylcysteine, abrogates diabetes-induced endothelial dysfunction
-
Pieper GM, Siebeneich W. Oral administration of the antioxidant, N-Acetylcysteine, abrogates diabetes-induced endothelial dysfunction. J Cardiovasc Pharmacol 1998; 32: 101-105
-
(1998)
J Cardiovasc Pharmacol
, vol.32
, pp. 101-105
-
-
Pieper, G.M.1
Siebeneich, W.2
-
31
-
-
48649103801
-
Long-term N-Acetylcysteine and L-Arginine administration reduces endothelial activation and systolic blood pressure in hypertensive patients with type 2 diabetes
-
Martina V, Masha A, Gigliardi VR, Brocato L, Manzato E, Berchio A., et al. Long-term N-Acetylcysteine and L-Arginine administration reduces endothelial activation and systolic blood pressure in hypertensive patients with type 2 diabetes. Diab Care 2008; 31: 940-944
-
(2008)
Diab Care
, vol.31
, pp. 940-944
-
-
Martina, V.1
Masha, A.2
Gigliardi, V.R.3
Brocato, L.4
Manzato, E.5
Berchio, A.6
-
32
-
-
33847141501
-
The role of N-Acetylcysteine treatment on anti-oxidative status in patients with type II diabetes mellitus
-
Ozkilic AC, Cengiz M, Ozaydin A, Cobanoglu A, Kanigur G. The role of N-Acetylcysteine treatment on anti-oxidative status in patients with type II diabetes mellitus. J Basic Clin Physiol Pharmacol 2006; 17: 245-254
-
(2006)
J Basic Clin Physiol Pharmacol
, vol.17
, pp. 245-254
-
-
Ozkilic, A.C.1
Cengiz, M.2
Ozaydin, A.3
Cobanoglu, A.4
Kanigur, G.5
-
33
-
-
29144455353
-
Effects of antioxidant supplementation on postprandial oxidative stress and endothelial dysfunction: A single-blind, 15-day clinical trial in patients with untreated type 2 diabetes, subjects with impaired glucose tolerance, and healthy controls
-
Neri S, Signorelli SS, Torrisi B, Pulvirenti D, Mauceri B, Abate G., et al. Effects of antioxidant supplementation on postprandial oxidative stress and endothelial dysfunction: a single-blind, 15-day clinical trial in patients with untreated type 2 diabetes, subjects with impaired glucose tolerance, and healthy controls. Clin Ther 2005; 27: 1764-1773
-
(2005)
Clin Ther
, vol.27
, pp. 1764-1773
-
-
Neri, S.1
Signorelli, S.S.2
Torrisi, B.3
Pulvirenti, D.4
Mauceri, B.5
Abate, G.6
-
34
-
-
84880136206
-
Effects of whey proteins on glycaemia and insulinaemia to an oral glucose load in healthy adults; A dose-response study
-
Gunnerud UJ, Ostman EM, Björck IM. Effects of whey proteins on glycaemia and insulinaemia to an oral glucose load in healthy adults; a dose-response study. Eur J Clin Nutr 2013; 67: 749-753
-
(2013)
Eur J Clin Nutr
, vol.67
, pp. 749-753
-
-
Gunnerud, U.J.1
Ostman, E.M.2
Björck, I.M.3
-
35
-
-
84863723847
-
Effects of different fractions of whey protein on postprandial lipid and hormone responses in type 2 diabetes
-
Mortensen LS, Holmer-Jensen J, Hartvigsen ML, Jensen VK, Astrup A, de Vrese M., et al. Effects of different fractions of whey protein on postprandial lipid and hormone responses in type 2 diabetes. Eur J Clin Nutr 2012; 66: 799-805
-
(2012)
Eur J Clin Nutr
, vol.66
, pp. 799-805
-
-
Mortensen, L.S.1
Holmer-Jensen, J.2
Hartvigsen, M.L.3
Jensen, V.K.4
Astrup, A.5
De Vrese, M.6
-
36
-
-
84872132092
-
Aged garlic extract reduces blood pressure in hypertensives: A dose-response trial
-
Ried K, Frank OR, Stocks NP. Aged garlic extract reduces blood pressure in hypertensives: a dose-response trial. Eur J Clin Nutr 2013; 67: 64-70
-
(2013)
Eur J Clin Nutr
, vol.67
, pp. 64-70
-
-
Ried, K.1
Frank, O.R.2
Stocks, N.P.3
-
37
-
-
84865126750
-
Effect of chromium dinicocysteinate supplementation on circulating levels of insulin, TNF-α, oxidative stress, and insulin resistance in type 2 diabetic subjects: Randomized, double-blind, placebo-controlled study
-
Jain SK, Kahlon G, Morehead L, Dhawan R, Lieblong B, Stapleton T., et al. Effect of chromium dinicocysteinate supplementation on circulating levels of insulin, TNF-α, oxidative stress, and insulin resistance in type 2 diabetic subjects: randomized, double-blind, placebo-controlled study. Mol Nutr Food Res 2012; 56: 1333-1341
-
(2012)
Mol Nutr Food Res
, vol.56
, pp. 1333-1341
-
-
Jain, S.K.1
Kahlon, G.2
Morehead, L.3
Dhawan, R.4
Lieblong, B.5
Stapleton, T.6
-
38
-
-
0031880858
-
Influence of reduced glutathione infusion on glucose metabolism in patients with non-insulin-dependent diabetes mellitus
-
De Mattia G, Bravi MC, Laurenti O, Cassone-Faldetta M, Armiento A, Ferri C., et al. Influence of reduced glutathione infusion on glucose metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism 1998; 47: 993-997
-
(1998)
Metabolism
, vol.47
, pp. 993-997
-
-
De Mattia, G.1
Bravi, M.C.2
Laurenti, O.3
Cassone-Faldetta, M.4
Armiento, A.5
Ferri, C.6
-
39
-
-
67749142090
-
Inhibition of lipid infusion-induced skeletal muscle insulin resistance by cotreatment with tempol and glutathione in mice
-
Kim BS, Cha HN, Kim YW, Kim JY, Dan JM, Park SY., et al. Inhibition of lipid infusion-induced skeletal muscle insulin resistance by cotreatment with tempol and glutathione in mice. J Pharmacol Sci 2009; 110: 370-380
-
(2009)
J Pharmacol Sci
, vol.110
, pp. 370-380
-
-
Kim, B.S.1
Cha, H.N.2
Kim, Y.W.3
Kim, J.Y.4
Dan, J.M.5
Park, S.Y.6
-
40
-
-
33646565956
-
Co-Administration of glutathione and nitric oxide enhances insulin sensitivity in Wistar rats
-
Guarino MP, Macedo MP. Co-Administration of glutathione and nitric oxide enhances insulin sensitivity in Wistar rats. Br J Pharmacol 2006; 147: 959-965
-
(2006)
Br J Pharmacol
, vol.147
, pp. 959-965
-
-
Guarino, M.P.1
MacEdo, M.P.2
-
41
-
-
84892181498
-
Effect of increasing glutathione with cysteine and glycine supplementation on mitochondrial fuel oxidation, insulin sensitivity and body composition in older HIV-infected patients
-
Nguyen D, Hsu JW, Jahoor F, Sekhar RV. Effect of increasing glutathione with cysteine and glycine supplementation on mitochondrial fuel oxidation, insulin sensitivity and body composition in older HIV-infected patients. J Clin Endocrinol Metab 2014; 99: 169-177
-
(2014)
J Clin Endocrinol Metab
, vol.99
, pp. 169-177
-
-
Nguyen, D.1
Hsu, J.W.2
Jahoor, F.3
Sekhar, R.V.4
-
42
-
-
79952447378
-
Current prospective on vitamin D, immune system, and chronic diseases
-
Borges MC, Martini LA, Rogero MM. Current prospective on vitamin D, immune system, and chronic diseases. Nutrition 2011; 27: 399-404
-
(2011)
Nutrition
, vol.27
, pp. 399-404
-
-
Borges, M.C.1
Martini, L.A.2
Rogero, M.M.3
-
43
-
-
84871282327
-
Vitamin D up-regulates glucose transporter 4 (GLUT4) translocation and glucose utilization mediated by cystathionine-γ-lyase (CSE) activation and H2S formation in 3T3L1 adipocytes
-
Manna P, Jain SK. Vitamin D up-regulates glucose transporter 4 (GLUT4) translocation and glucose utilization mediated by cystathionine-γ-lyase (CSE) activation and H2S formation in 3T3L1 adipocytes. J Biol Chem 2012; 287: 42324-42332
-
(2012)
J Biol Chem
, vol.287
, pp. 42324-42332
-
-
Manna, P.1
Jain, S.K.2
-
44
-
-
84874071061
-
In African American type 2 diabetic patients, is vitamin D deficiency associated with lower blood levels of hydrogen sulfide and cyclic adenosine monophosphate, and elevated oxidative stress?
-
Jain SK, Manna P, Micinski D, Lieblong BJ, Kahlon G, Morehead L., et al. In African American type 2 diabetic patients, is vitamin D deficiency associated with lower blood levels of hydrogen sulfide and cyclic adenosine monophosphate, and elevated oxidative stress?. Antioxid Redox Signal 2013; 18: 1154-1158
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 1154-1158
-
-
Jain, S.K.1
Manna, P.2
Micinski, D.3
Lieblong, B.J.4
Kahlon, G.5
Morehead, L.6
|