Influence of reduced glutathione infusion on glucose metabolism in patients with non-insulin-dependent diabetes mellitus

Metabolism: Clinical and Experimental

Volumn 47, Issue 8, 1998, Pages 993-997

  De Mattia, G ^a   Bravi, M C ^a   Laurenti, O ^a   Cassone Faldetta, M ^a   Armiento, A ^a   Ferri, C ^a   Balsano, F ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; INSULIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROCYTE LEVEL; FEMALE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; INSULIN SENSITIVITY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 0031880858     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(98)90357-2     Document Type: Article

References (26)

1. Beutler E, Gelbart T: Plasma glutathione in healthy and in patients with malignant disease. J Lab Clin Med 105:581-584, 1985
2. Daimant E, Laudberg E, London IM: The metabolic behavior of reduced glutathione in human and avian erythrocytes. J Biol Chem 213:769-776, 1955
3. Shan Z, Tan D, Satriano J, et al: Intracellular glutathione influences collagen generation by mesangial cells. Kidney Int 46:388-395, 1994
4. Fujii S, Dale GL, Beutler E: Glutathione dependent protection against oxidative damage of the human red cell membrane. Blood 63:1096-1101, 1984
5. Andreoli SP, Mallett CP, Bergstein JM: Role of glutathione in protecting endothelial cells against hydrogen peroxide oxidant injury. J Lab Clin Med 108:190-198, 1986
6. 2 in human umbilical vein endothelial cells cultured in high glucose medium. Diabetologia 37:264-269, 1994
7. Ghiselli A, Laurenti O, De Mattia G, et al: Salicylate hydroxylation as an early marker of in vivo oxidative stress in diabetic patients. Free Radical Biol Med 13:621-626, 1994
8. Jenning PE, Jones AF, Florkowski CM, et al: Increased diene conjugates in diabetic subjects with microangiopathy. Diabetic Med 4:452-456, 1987
9. Wolf SP: The potential role of oxidative stress in the diabetic complications: novel implications for theory and therapy, in Gabbe MJC (ed): Diabetic Complications, Scientific and Clinical Aspects. Edinburgh, UK, Churchill Livingstone, 1987, pp 167-220
10. Paolisso G, D'Amore A, Giugliano D, et al: Pharmacologic doses of vitamin E improve insulin action in healthy subjects and non-insulin-dependent diabetic patients. Am J Clin Nutr 57:650-656, 1993
11. Paolisso G, Di Maro G, Pizza G, et al: Plasma GSH/GSSG affects glucose homeostasis in healthy subjects and non-insulin-dependent diabetics. Am J Physiol 263:E435-E440, 1992
12. Hentze MW, Rouault TA, Harford JB, et al: Oxidation-reduction and the molecular mechanism of regulatory RNA-protein interaction. Science 244:357-359, 1989
13. Hwang C, Sinskey AJ, Lodish HF: Oxidized redox state of glutathione in the endoplasmic reticulum. Science 257:1496-1502, 1992
14. Ziegler DM: Role of reversible oxidation-reduction of enzyme thiols-disulfides in metabolic regulation. Ann Rev Biochem 54:305-329, 1985
15. Cappell RE, Gilbert HF: Thiol/disulfide exchange between 3-hydroxy-3-methyglutaryl-CoA reductase and glutathione. J Biol Chem 263:12204-12212, 1988
16. De Fronzo RA, Tobin JD, Andres R: Glucose clamp tecnique: A method for quantifying insulin secretion and resistance. Am J Physiol 237:E214-E223, 1979
17. Anderson ME: Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol 113:548-557, 1987
18. Griffith OW: Determination of glutathione disulfide using glutathione reductase and 2-vinylpyridine. Ann Biochem 106:207-212, 1980
19. Ammon HPT, Hehl KH, Enz G, et al: Cysteine analogues potentiate glucose-induced insulin release in vitro. Diabete 35:1390-1396, 1986
20. Murakami K, Kondo T, Ohtsuka Y, et al: Impairment of glutathione metabolism in erythrocytes from patients with diabetes mellitus. Metabolism 38:753-758, 1989
21. Yoshida K, Hirokawa J, Tagami S, et al: Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: Regulation of glutathione synthesis and efflux. Diabetologia 38:201-210, 1995
22. De Mattia G, Laurenti O, Bravi C, et al: Effect of aldose reductase inhibition on glutathione redox status in erythrocytes of diabetic patients. Metabolism 43:965-968, 1994
23. 2 in high glucose medium. Diabetes 44:520-526, 1995
24. Isaacs J, Binkley F: Glutathione dependent control protein disulfide-sulfhydryl content by subcellular fractions of hepatic tissue. Biochim Biophys Acta 497:192-204, 1977
25. Shii K, Yokono K, Baba S, et al: Purification and characterization of insulin-degrading enzyme from human erythrocytes. Diabetes 35:675-683, 1986
26. Duckworth WC: Insulin degradation: Mechanisms, products, and significance. Endocrine Rev 9:319-345, 1988