메뉴 건너뛰기




Volumn 39, Issue 2, 2015, Pages 141-147

Structural investigation of ginsenoside Rf with PPARγ major transcriptional factor of adipogenesis and its impact on adipocyte

Author keywords

Adipocyte; Ginsenoside Rf; Molecular docking; Panax ginseng; PPAR

Indexed keywords

GINSENOSIDE RF; LIPID; PERILIPIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 84926167614     PISSN: 12268453     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jgr.2014.10.002     Document Type: Article
Times cited : (31)

References (34)
  • 1
    • 4444228888 scopus 로고    scopus 로고
    • World Health Organization
    • World Health Organization. Obesity and overweight. Available from: http://www.who.int/dietphysicalactivity/publications/facts/obesity/en/print.html.
    • Obesity and Overweight
  • 2
    • 0036512243 scopus 로고    scopus 로고
    • The effects of obesity, smoking, and drinking on medical problems and costs
    • Sturm R. The effects of obesity, smoking, and drinking on medical problems and costs. Health Aff (Millwood) 2002;21:245-53.
    • (2002) Health Aff (Millwood) , vol.21 , pp. 245-253
    • Sturm, R.1
  • 3
    • 78851468865 scopus 로고    scopus 로고
    • The economic burden of obesity worldwide: A systematic review of the direct costs of obesity
    • Withrow D, Alter DA. The economic burden of obesity worldwide: a systematic review of the direct costs of obesity. Obes Rev 2011;12:131-41.
    • (2011) Obes Rev , vol.12 , pp. 131-141
    • Withrow, D.1    Alter, D.A.2
  • 4
    • 34848851922 scopus 로고    scopus 로고
    • Angiogenesis modulates adipogenesis and obesity
    • Cao Y. Angiogenesis modulates adipogenesis and obesity. J Clin Invest 2007;117:2362-8.
    • (2007) J Clin Invest , vol.117 , pp. 2362-2368
    • Cao, Y.1
  • 5
    • 17744393520 scopus 로고    scopus 로고
    • Application of bioreactor systems for large scale production of horticultural and medicinal plants
    • Paek KY, Chakrabarty D, Hahn EJ. Application of bioreactor systems for large scale production of horticultural and medicinal plants. Plant Cell Tissue Organ Cult 2005;81:287-300.
    • (2005) Plant Cell Tissue Organ Cult , vol.81 , pp. 287-300
    • Paek, K.Y.1    Chakrabarty, D.2    Hahn, E.J.3
  • 8
    • 0034654608 scopus 로고    scopus 로고
    • Differentiation and authentication of panax ginseng, panax quinquefolius, and ginseng products by using hplc/ms
    • Chan TW, But PP, Cheng SW, Kwok IM, Lau FW, Xu HX. Differentiation and authentication of Panax ginseng, Panax quinquefolius, and ginseng products by using HPLC/MS. Anal Chem 2000;72:1281-7.
    • (2000) Anal Chem , vol.72 , pp. 1281-1287
    • Chan, T.W.1    But, P.P.2    Cheng, S.W.3    Kwok, I.M.4    Lau, F.W.5    Xu, H.X.6
  • 9
    • 77953812705 scopus 로고    scopus 로고
    • Induction of cyp3a4 and mdr1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside rf through constitutive androstane receptor- and pregnane x receptor-mediated pathways
    • Yue L, Qi W, Xiaomin Y, Yan L. Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways. Eur J Pharmacol 2010;640:46-54.
    • (2010) Eur J Pharmacol , vol.640 , pp. 46-54
    • Yue, L.1    Qi, W.2    Xiaomin, Y.3    Yan, L.4
  • 10
    • 84891944492 scopus 로고    scopus 로고
    • Induction of g2/m phase cell cycle arrest and apoptosis by ginsenoside rf in human osteosarcoma mg-63 cells through the mitochondrial pathway
    • Wen JS, He L, Yue HZ. Induction of G2/M phase cell cycle arrest and apoptosis by ginsenoside Rf in human osteosarcoma MG-63 cells through the mitochondrial pathway. Oncol Rep 2014;1:305-13.
    • (2014) Oncol Rep , vol.1 , pp. 305-313
    • Wen, J.S.1    He, L.2    Yue, H.Z.3
  • 11
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • Desvergene B, Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 1999;20:649-88.
    • (1999) Endocr Rev , vol.20 , pp. 649-688
    • Desvergene, B.1    Wahli, W.2
  • 12
    • 79251524915 scopus 로고    scopus 로고
    • Can we trust docking results? Evaluation of seven commonly used programs on pdbbind database
    • Plewczynski D, Zniewski M, Augustyniak R, Ginalski K. Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database. J Comput Chem 2011;32:742-55.
    • (2011) J Comput Chem , vol.32 , pp. 742-755
    • Plewczynski, D.1    Zniewski, M.2    Augustyniak, R.3    Ginalski, K.4
  • 13
    • 0029705324 scopus 로고    scopus 로고
    • Automated docking of flexible ligands: Applications of autodock
    • Goodsell DS, Morris GM, Olson AJ. Automated docking of flexible ligands: applications of AutoDock. J Mol Recognit 1996;9:1-5.
    • (1996) J Mol Recognit , vol.9 , pp. 1-5
    • Goodsell, D.S.1    Morris, G.M.2    Olson, A.J.3
  • 14
    • 0031552362 scopus 로고    scopus 로고
    • Development and validation of a genetic algorithm for flexible docking
    • Jones G, Willett P, Glen RC, Leach AR, Taylor R. Development and validation of a genetic algorithm for flexible docking. J Mol Biol 1997;267:727-48.
    • (1997) J Mol Biol , vol.267 , pp. 727-748
    • Jones, G.1    Willett, P.2    Glen, R.C.3    Leach, A.R.4    Taylor, R.5
  • 15
    • 0030599010 scopus 로고    scopus 로고
    • A fast flexible docking method using an incremental construction algorithm
    • Rarey M, Kramer B, Lengauer T, Klebe G. A fast flexible docking method using an incremental construction algorithm. J Mol Biol 1996;261:470-89.
    • (1996) J Mol Biol , vol.261 , pp. 470-489
    • Rarey, M.1    Kramer, B.2    Lengauer, T.3    Klebe, G.4
  • 18
    • 11644261806 scopus 로고    scopus 로고
    • Automated docking using a lamarckian genetic algorithm and an empirical binding free energy function
    • Morris GM, Goodsell DS, Halliday RS. Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function. J Comp Chem 1998;19:1639-62.
    • (1998) J Comp Chem , vol.19 , pp. 1639-1662
    • Morris, G.M.1    Goodsell, D.S.2    Halliday, R.S.3
  • 19
    • 33750083590 scopus 로고    scopus 로고
    • Critical assessment of the automated autodock as a new docking tool for virtual screening
    • Park H, Lee J, Lee S. Critical assessment of the automated AutoDock as a new docking tool for virtual screening. Proteins 2006;65:549-54.
    • (2006) Proteins , vol.65 , pp. 549-554
    • Park, H.1    Lee, J.2    Lee, S.3
  • 21
    • 84866078172 scopus 로고    scopus 로고
    • Molecular docking studies of anti-apoptotic bcl-2, bcl-xl, and mcl-1 proteins with ginsenosides from panax ginseng
    • Sathishkumar N, Sathiyamoorthy S, Ramya M, Yang DU, Lee HN, Yang DC. Molecular docking studies of anti-apoptotic BCL-2, BCL-XL, and MCL-1 proteins with ginsenosides from Panax ginseng. J Enzyme Inhib Med Chem 2012;27:685-92.
    • (2012) J Enzyme Inhib Med Chem , vol.27 , pp. 685-692
    • Sathishkumar, N.1    Sathiyamoorthy, S.2    Ramya, M.3    Yang, D.U.4    Lee, H.N.5    Yang, D.C.6
  • 24
    • 84877721218 scopus 로고    scopus 로고
    • Computer-aided identification of egfr tyrosine kinase inhibitors using ginsenosides from panax ginseng
    • Sathishkumar N, Karpagam V, Sathiyamoorthy S, Min JW, Kim YJ, Yang DC. Computer-aided identification of EGFR tyrosine kinase inhibitors using ginsenosides from Panax ginseng. Comput Biol Med 2013;43:786-97.
    • (2013) Comput Biol Med , vol.43 , pp. 786-797
    • Sathishkumar, N.1    Karpagam, V.2    Sathiyamoorthy, S.3    Min, J.W.4    Kim, Y.J.5    Yang, D.C.6
  • 25
  • 26
    • 78049518795 scopus 로고    scopus 로고
    • Multi-targeted natural products evaluation based on biological activity prediction with pass
    • Lagunin A, Filimonov D, Poroikov V. Multi-targeted natural products evaluation based on biological activity prediction with PASS. Curr Pharm Des 2010;16:1703-17.
    • (2010) Curr Pharm Des , vol.16 , pp. 1703-1717
    • Lagunin, A.1    Filimonov, D.2    Poroikov, V.3
  • 27
    • 84921310261 scopus 로고    scopus 로고
    • Ginsenoside f2 possesses anti-obesity activity via binding with pparg and inhibiting adipocyte differentiation in the 3t3-l1 cell line
    • [Epub ahead of print]
    • Fayeza MS, Natarajan S, Yeon JK, Se YK, Deok CY. Ginsenoside F2 possesses anti-obesity activity via binding with PPARg and inhibiting adipocyte differentiation in the 3T3-L1 cell line. J Enzyme Inhib Med Chem 2014 Mar 25. http://dx.doi.org/10.3109/14756366.2013.871006 [Epub ahead of print].
    • (2014) J Enzyme Inhib Med Chem
    • Fayeza, M.S.1    Natarajan, S.2    Yeon, J.K.3    Se, Y.K.4    Deok, C.Y.5
  • 28
    • 79551672505 scopus 로고    scopus 로고
    • Synthesis of novel ppara/c dual agonists as potential drugs for the treatment of the metabolic syndrome and diabetes type ii designed using a new de novo design program protobuild
    • Yushma BA, Therese R, Michael RJ, Christos K, Jon S, Robert GC, Joseph MS, William DOH, Jonathan RH, Rolf KB, et al. Synthesis of novel PPARa/c dual agonists as potential drugs for the treatment of the metabolic syndrome and diabetes type II designed using a new de novo design program PROTOBUILD. Org Biomol Chem 2011;9:1169-88.
    • (2011) Org Biomol Chem , vol.9 , pp. 1169-1188
    • Yushma, B.A.1    Therese, R.2    Michael, R.J.3    Christos, K.4    Jon, S.5    Robert, G.C.6    Joseph, M.S.7    William, D.O.H.8    Jonathan, R.H.9    Rolf, K.B.10
  • 30
    • 34249793679 scopus 로고    scopus 로고
    • Computer-assisted methods in chemical toxicity pre diction
    • Mohan CG, Gandhi T, Garg D, Shinde R. Computer-assisted methods in chemical toxicity pre diction. Mini Rev Med Chem 2007;7:499-507.
    • (2007) Mini Rev Med Chem , vol.7 , pp. 499-507
    • Mohan, C.G.1    Gandhi, T.2    Garg, D.3    Shinde, R.4
  • 31
    • 34547581106 scopus 로고    scopus 로고
    • Regulation of adipocyte lipolysis by degradation of the perilipin protein
    • Kovsan J, Ben RR, Souza SC, Greenberg AS, Rudich A. Regulation of adipocyte lipolysis by degradation of the perilipin protein. J Biol Chem 2007;282: 21704-11.
    • (2007) J Biol Chem , vol.282 , pp. 21704-21711
    • Kovsan, J.1    Ben, R.R.2    Souza, S.C.3    Greenberg, A.S.4    Rudich, A.5
  • 34
    • 84938420180 scopus 로고    scopus 로고
    • In silico screening of ginsenoside rh1 with pparg and in vitro analysis on 3t3-l1 cell line
    • Fayeza MS, Natarajan S, Yeon JK, Deok CY. In silico screening of ginsenoside Rh1 with PPARg and in vitro analysis on 3T3-L1 cell line. Mol Simulation 2014. http://dx.doi.org/10.1080/08927022.2014.970188.
    • (2014) Mol Simulation
    • Fayeza, M.S.1    Natarajan, S.2    Yeon, J.K.3    Deok, C.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.