Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris

Biotechnology Journal

Volumn 10, Issue 4, 2015, Pages 623-635

  Emmerstorfer, Anita ^a   Wimmer Teubenbacher, Miriam ^b   Wriessnegger, Tamara ^a   Leitner, Erich ^b   Müller, Monika ^c   Kaluzna, Iwona ^c   Schürmann, Martin ^c   Mink, Daniel ^c   Zellnig, Günther ^d   Schwab, Helmut ^a,b   Pichler, Harald ^a,b  

^a AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

^b GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^c DSM RESOLVE   (Netherlands)

^d UNIVERSITY OF GRAZ   (Austria)

Author keywords

Cytochrome P450 reductase; Membrane protein expression; Protein stability; Whole cell conversion; Yeast

Indexed keywords

BIOCONVERSION; BIOLOGICAL MEMBRANES; ENZYME ACTIVITY; ENZYMES; PROTEINS;

ARABIDOPSIS THALIANA; CYTOCHROME C REDUCTASE; CYTOCHROME P450 ENZYMES; CYTOCHROME P450 REDUCTASE; HYDROPHOBIC MOLECULES; MEMBRANE PROTEIN EXPRESSIONS; PROTEIN STABILITY; WHOLE-CELL CONVERSION;

YEAST;

CYTOCHROME P450 REDUCTASE; CYTOCHROME REDUCTASE; MEMBRANE PROTEIN; OXYGENASE; PREMNASPIRODIENE OXYGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; UNCLASSIFIED DRUG; VALENCENE; ARABIDOPSIS PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CYTOCHROME P450; FUNGAL PROTEIN; ICE2 PROTEIN, ARABIDOPSIS; SESQUITERPENE;

ARABIDOPSIS THALIANA; ARTICLE; BIOTRANSFORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME STABILITY; FUNGAL CELL; GENE INACTIVATION; GENE OVEREXPRESSION; HYDROXYLATION; HYOSCYAMUS; ICE2 GENE; IMMUNOBLOTTING; IN VIVO STUDY; KOMAGATAELLA PASTORIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; UPREGULATION; CHEMISTRY; GENETICS; METABOLISM; PICHIA; PROTEIN STABILITY;

ARABIDOPSIS THALIANA; HYOSCYAMUS MUTICUS; PICHIA PASTORIS; SACCHAROMYCES CEREVISIAE;

ARABIDOPSIS PROTEINS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CYTOCHROME P-450 ENZYME SYSTEM; FUNGAL PROTEINS; PICHIA; PROTEIN STABILITY; SACCHAROMYCES CEREVISIAE; SESQUITERPENES; UP-REGULATION;

EID: 84926160273     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201400780     Document Type: Article

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