메뉴 건너뛰기




Volumn 54, Issue 1, 1998, Pages 8-13

Yeast expressed cytochrome P450 2D6 (CYP2D6) exposed on the external face of plasma membrane is functionally competent

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 REDUCTASE; DEXTROMETHORPHAN; HYDROPEROXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

EID: 2642611948     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.54.1.8     Document Type: Article
Times cited : (35)

References (38)
  • 1
    • 0242668517 scopus 로고
    • Human anti-endoplasmic reticulum autoantobodies appearing in a drug induced hepatitis are directed against a human liver cytochrome P450 that hydroxylates the drug
    • Beaune PH, Dansette PM, Kiffel L, Finck M, Amar C, Leroux JP, and Homberg JC (1987) Human anti-endoplasmic reticulum autoantobodies appearing in a drug induced hepatitis are directed against a human liver cytochrome P450 that hydroxylates the drug. Proc Natl Acad Sci USA 84:551-555.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 551-555
    • Beaune, P.H.1    Dansette, P.M.2    Kiffel, L.3    Finck, M.4    Amar, C.5    Leroux, J.P.6    Homberg, J.C.7
  • 3
    • 0025341427 scopus 로고
    • Anti-liver endoplasmic reticulum autoantibodies are directed against human cytochrome P450 1A2: A specific marker of dihydralazine-induced hepatitis
    • Bourdi M, Larrey D, Nataf J, Bernuau J, Pessayre D, Iwasaki M, Guengerich FP, and Beaune PH (1990) Anti-liver endoplasmic reticulum autoantibodies are directed against human cytochrome P450 1A2: a specific marker of dihydralazine-induced hepatitis. J Clin Invest 85:1967-1973.
    • (1990) J Clin Invest , vol.85 , pp. 1967-1973
    • Bourdi, M.1    Larrey, D.2    Nataf, J.3    Bernuau, J.4    Pessayre, D.5    Iwasaki, M.6    Guengerich, F.P.7    Beaune, P.H.8
  • 4
    • 0028838294 scopus 로고
    • Functional complementation of a null mutation of the yeast Saccharomyces cerevisiae plasma membrane H(+)-ATPase by a plant H(+)-ATPase gene
    • de Kerchove d'Exaerde A, Supply P, Dufour JP, Bogaerts P, Thines D, Goffeau A, and Boutry M (1995) Functional complementation of a null mutation of the yeast Saccharomyces cerevisiae plasma membrane H(+)-ATPase by a plant H(+)-ATPase gene. J Biol Chem 270:23828-23837.
    • (1995) J Biol Chem , vol.270 , pp. 23828-23837
    • De Kerchove D'Exaerde, A.1    Supply, P.2    Dufour, J.P.3    Bogaerts, P.4    Thines, D.5    Goffeau, A.6    Boutry, M.7
  • 5
    • 0031936276 scopus 로고    scopus 로고
    • Self-sufficient biosynthesis of pregnenolone and progesterone in engineered yeast
    • Duport C, Spagnoli R, Degryse E, and Pompon D (1998) Self-sufficient biosynthesis of pregnenolone and progesterone in engineered yeast. Nat Biotechnol 16: 186-189.
    • (1998) Nat Biotechnol , vol.16 , pp. 186-189
    • Duport, C.1    Spagnoli, R.2    Degryse, E.3    Pompon, D.4
  • 6
    • 0029786269 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 is a cell surface autoantigen in halothane hepatitis
    • Eliasson E and Kenna JG (1996) Cytochrome P450 2E1 is a cell surface autoantigen in halothane hepatitis. Mol Pharmacol 50:573-582.
    • (1996) Mol Pharmacol , vol.50 , pp. 573-582
    • Eliasson, E.1    Kenna, J.G.2
  • 7
    • 0023568113 scopus 로고
    • MPTP, the neurotoxin inducing Parkinson's disease is a potent competitive inhibitor of human and rat cytochrome isozymes (P450buf, P450db1) catalyzing debrisoquine 4-hydroxylation
    • Fonne-Pfister R, Bargetzi MJ, and Meyer UA (1987) MPTP, the neurotoxin inducing Parkinson's disease is a potent competitive inhibitor of human and rat cytochrome isozymes (P450buf, P450db1) catalyzing debrisoquine 4-hydroxylation. Biochem Biophys Res Commun 148:1144-1150.
    • (1987) Biochem Biophys Res Commun , vol.148 , pp. 1144-1150
    • Fonne-Pfister, R.1    Bargetzi, M.J.2    Meyer, U.A.3
  • 8
    • 0030473382 scopus 로고    scopus 로고
    • Contribution of human cytochrome P450 to benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol metabolism, as predicted from heterologous expression in yeast
    • Gautier JC, Lecoeur S, Cosme J, Perret A, Urban P, Beaune PH and Pompon D (1996) Contribution of human cytochrome P450 to benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol metabolism, as predicted from heterologous expression in yeast. Pharmacogenetics 6:489-499.
    • (1996) Pharmacogenetics , vol.6 , pp. 489-499
    • Gautier, J.C.1    Lecoeur, S.2    Cosme, J.3    Perret, A.4    Urban, P.5    Beaune, P.H.6    Pompon, D.7
  • 9
    • 0027976519 scopus 로고
    • Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs
    • Ghersi-Egea JF, Leninger-Muller B, Suleman G, Siest G and Minn A (1994) Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs. J Neurochem 62: 1089-1096.
    • (1994) J Neurochem , vol.62 , pp. 1089-1096
    • Ghersi-Egea, J.F.1    Leninger-Muller, B.2    Suleman, G.3    Siest, G.4    Minn, A.5
  • 10
    • 0023813850 scopus 로고
    • Anti-liver -kidney microsome antibody recognizes a cytochrome P-450 from IID subfamily
    • Gueguen M, Meunier-Rotival M, Bernard O and Alvarez F (1988) Anti-liver -kidney microsome antibody recognizes a cytochrome P-450 from IID subfamily. J Exp Med 168:801-806.
    • (1988) J Exp Med , vol.168 , pp. 801-806
    • Gueguen, M.1    Meunier-Rotival, M.2    Bernard, O.3    Alvarez, F.4
  • 11
    • 0026336750 scopus 로고
    • Expression of mammalian cytochrome P450 enzymes using yeast-based vectors
    • Guengerich FP, Bryan WR, Sari MA and Ross JT (1991) Expression of mammalian cytochrome P450 enzymes using yeast-based vectors. Methods Enzymol 206:130-145.
    • (1991) Methods Enzymol , vol.206 , pp. 130-145
    • Guengerich, F.P.1    Bryan, W.R.2    Sari, M.A.3    Ross, J.T.4
  • 12
    • 0018417573 scopus 로고
    • B-type cytochromes in plasma membranes isolated from rat liver, in comparison with those of endomembranes
    • Jarasch ED, Kartenbeck J, Bruder J, Fink A, Morré DJ, and Franke WW (1979) B-type cytochromes in plasma membranes isolated from rat liver, in comparison with those of endomembranes. J Cell Biol 80:37-52.
    • (1979) J Cell Biol , vol.80 , pp. 37-52
    • Jarasch, E.D.1    Kartenbeck, J.2    Bruder, J.3    Fink, A.4    Morré, D.J.5    Franke, W.W.6
  • 13
    • 0024560260 scopus 로고
    • A human cytochrome P-450 is recognized by anti-liver/kidney microsome antibodies in autoimmune hepatitis
    • Kiffel L, Loeper J, Homberg JC, and Leroux JP (1989) A human cytochrome P-450 is recognized by anti-liver/kidney microsome antibodies in autoimmune hepatitis. Biochem Biophys Res Commun 159:283-288.
    • (1989) Biochem Biophys Res Commun , vol.159 , pp. 283-288
    • Kiffel, L.1    Loeper, J.2    Homberg, J.C.3    Leroux, J.P.4
  • 14
    • 0028114922 scopus 로고
    • A genetic approach to elucidating eukaryotic iron metabolism
    • Klausner RD and Dancis A (1994) A genetic approach to elucidating eukaryotic iron metabolism. FEBS Lett 355:109-113.
    • (1994) FEBS Lett , vol.355 , pp. 109-113
    • Klausner, R.D.1    Dancis, A.2
  • 15
    • 0029790276 scopus 로고    scopus 로고
    • Tienilic acid-induced autoimmune hepatitis: Anti-liver and -kidney microsomal antibodies type 2 autoantibodies recognize a three-site conformational epitope on cytochrome P4502C9
    • Lecoeur S, Andre C, and Beaune PH (1996) Tienilic acid-induced autoimmune hepatitis: anti-liver and -kidney microsomal antibodies type 2 autoantibodies recognize a three-site conformational epitope on cytochrome P4502C9. Mol Pharmacol 50:326-333.
    • (1996) Mol Pharmacol , vol.50 , pp. 326-333
    • Lecoeur, S.1    Andre, C.2    Beaune, P.H.3
  • 16
    • 0026727963 scopus 로고
    • Human anti-cytochrome P450 antibodies in aromatic anticonvulsivants-induced hypersensitivity reactions
    • Leeder JS, Riley RJ, Cook VA, and Spielberg P (1992) Human anti-cytochrome P450 antibodies in aromatic anticonvulsivants-induced hypersensitivity reactions. J Pharmacol Exp Ther 263:360-367.
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 360-367
    • Leeder, J.S.1    Riley, R.J.2    Cook, V.A.3    Spielberg, P.4
  • 17
    • 0029946913 scopus 로고    scopus 로고
    • Evidence for the Saccharomyces cerevisiae ferrireductase system being a multicomponent electron transport chain
    • Lesuisse E, Casteras-Simon M, and Labbe P (1996) Evidence for the Saccharomyces cerevisiae ferrireductase system being a multicomponent electron transport chain. J Biol Chem 271:13578-13583.
    • (1996) J Biol Chem , vol.271 , pp. 13578-13583
    • Lesuisse, E.1    Casteras-Simon, M.2    Labbe, P.3
  • 18
    • 0031277611 scopus 로고    scopus 로고
    • Cytochrome P50 reductase is responsible for the ferrireductase activity associated with isolated plasma membranes of Saccharomyces cerevisiae
    • Lesuisse E, Casteras-Simon M, and Labbe P (1997) Cytochrome P50 reductase is responsible for the ferrireductase activity associated with isolated plasma membranes of Saccharomyces cerevisiae. FEMS Microbiol Lett 156:147-152.
    • (1997) FEMS Microbiol Lett , vol.156 , pp. 147-152
    • Lesuisse, E.1    Casteras-Simon, M.2    Labbe, P.3
  • 19
    • 0024547091 scopus 로고
    • Presence of covalently bound metabolites on rat hepatocyte plasma membrane proteins after administration of isaxonine, a drug leading to immunoallergic hepatitis in man
    • Loeper J, Descatoire V, Amouyal G, Letteron P, Larrey D, and Pessayre D (1989) Presence of covalently bound metabolites on rat hepatocyte plasma membrane proteins after administration of isaxonine, a drug leading to immunoallergic hepatitis in man. Hepatology 9:675-678.
    • (1989) Hepatology , vol.9 , pp. 675-678
    • Loeper, J.1    Descatoire, V.2    Amouyal, G.3    Letteron, P.4    Larrey, D.5    Pessayre, D.6
  • 22
    • 0031968074 scopus 로고    scopus 로고
    • Topology inversion of P450 2D6 (CYP2D6) in the endoplasmic reticulum is not required for plasma membrane transport
    • Loeper J, Le Berre A, Pompon D (1998) Topology inversion of P450 2D6 (CYP2D6) in the endoplasmic reticulum is not required for plasma membrane transport. Mol Pharmacol 53:408-414.
    • (1998) Mol Pharmacol , vol.53 , pp. 408-414
    • Loeper, J.1    Le Berre, A.2    Pompon, D.3
  • 23
    • 0024580945 scopus 로고
    • The major target antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is P450 db1
    • Manns MP, Johnson EF, Griffin KJ, Tan EM, and Sullivan KF (1989) The major target antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is P450 db1. J Clin Invest 83:1066-1072.
    • (1989) J Clin Invest , vol.83 , pp. 1066-1072
    • Manns, M.P.1    Johnson, E.F.2    Griffin, K.J.3    Tan, E.M.4    Sullivan, K.F.5
  • 24
    • 0025992973 scopus 로고
    • LKM1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P450 monooxygenase
    • Manns MP, Griffin KJ, Sullivan KF, and Johnson EF (1991) LKM1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P450 monooxygenase. J Clin Invest 88:1370-1378.
    • (1991) J Clin Invest , vol.88 , pp. 1370-1378
    • Manns, M.P.1    Griffin, K.J.2    Sullivan, K.F.3    Johnson, E.F.4
  • 25
    • 0017113579 scopus 로고
    • Studies on hydroperoxide-dependent substrate hydroxylation by purified liver microsomal cytochrome P-450
    • Nordblom GD, White RE, and Coon MJ (1976) Studies on hydroperoxide-dependent substrate hydroxylation by purified liver microsomal cytochrome P-450. Arch Biochem Biophys 175:524-533.
    • (1976) Arch Biochem Biophys , vol.175 , pp. 524-533
    • Nordblom, G.D.1    White, R.E.2    Coon, M.J.3
  • 26
    • 0029804088 scopus 로고    scopus 로고
    • Study of the B cell response to cytochrome P450IID6 in sera from chronic hepatitis C patients
    • Parez N, Herzog D, Jacqz-Aigrain E, Homberg JC, and Alvarez F (1996) Study of the B cell response to cytochrome P450IID6 in sera from chronic hepatitis C patients. Clin Exp Immunol 106:336-343.
    • (1996) Clin Exp Immunol , vol.106 , pp. 336-343
    • Parez, N.1    Herzog, D.2    Jacqz-Aigrain, E.3    Homberg, J.C.4    Alvarez, F.5
  • 27
    • 0029776005 scopus 로고    scopus 로고
    • Yeast expression of animals and plant P450s in optimized redox environments
    • Pompon D, Louerat B, Bronine A, and Urban P (1996) Yeast expression of animals and plant P450s in optimized redox environments. Methods Enzymol 272:51-64.
    • (1996) Methods Enzymol , vol.272 , pp. 51-64
    • Pompon, D.1    Louerat, B.2    Bronine, A.3    Urban, P.4
  • 30
    • 0021113820 scopus 로고
    • Fast and efficient purification of yeast plasma membranes using cationic silica microbeads
    • Schmidt R, Ackermann R, Kratky Z, Wasserman B, and Jacobson B (1983) Fast and efficient purification of yeast plasma membranes using cationic silica microbeads. Biochim Biophy Acta 732:421-427.
    • (1983) Biochim Biophy Acta , vol.732 , pp. 421-427
    • Schmidt, R.1    Ackermann, R.2    Kratky, Z.3    Wasserman, B.4    Jacobson, B.5
  • 31
    • 0018960713 scopus 로고
    • Distribution of enzymes involved in metabolism of polycyclic aromatic hydrocarbons among rat liver endomembranes and plasma membranes
    • Stasiecki P and Oesch F (1980) Distribution of enzymes involved in metabolism of polycyclic aromatic hydrocarbons among rat liver endomembranes and plasma membranes. Eur J Cell Biol 21:79-92.
    • (1980) Eur J Cell Biol , vol.21 , pp. 79-92
    • Stasiecki, P.1    Oesch, F.2
  • 32
    • 0026512229 scopus 로고
    • Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes
    • Suzuki T, Fujita S, Narimatsu S, Masubuchi Y, Tachibana M, Ohta S, and Hirobe M (1992) Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes. FASEB J 6:771-776.
    • (1992) FASEB J , vol.6 , pp. 771-776
    • Suzuki, T.1    Fujita, S.2    Narimatsu, S.3    Masubuchi, Y.4    Tachibana, M.5    Ohta, S.6    Hirobe, M.7
  • 33
    • 0025779409 scopus 로고
    • Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): Potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6
    • Tyndale R, Sunahara FR, Inaba T, Kalow W, Gonzalez FJ, and Niznik HB (1991) Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6. Mol Pharmacol 40:63-68.
    • (1991) Mol Pharmacol , vol.40 , pp. 63-68
    • Tyndale, R.1    Sunahara, F.R.2    Inaba, T.3    Kalow, W.4    Gonzalez, F.J.5    Niznik, H.B.6
  • 35
    • 0026503184 scopus 로고
    • Presence of functionally active cytochrome P-450 IIE1 in the plasma membrane of rat hepatocytes
    • Wu D and Cederbaum AI (1992) Presence of functionally active cytochrome P-450 IIE1 in the plasma membrane of rat hepatocytes. Hepatology 15:515-524.
    • (1992) Hepatology , vol.15 , pp. 515-524
    • Wu, D.1    Cederbaum, A.I.2
  • 38
    • 0026082909 scopus 로고
    • Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae
    • Zinser E, Sperka-Gottlieb CD, Fasch EV, Kohlwein SD, Paltauf F, and Daum G (1991) Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae. J Bacteriol 173:2026-2034.
    • (1991) J Bacteriol , vol.173 , pp. 2026-2034
    • Zinser, E.1    Sperka-Gottlieb, C.D.2    Fasch, E.V.3    Kohlwein, S.D.4    Paltauf, F.5    Daum, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.