The role of TRPV1 channels in carrageenan-induced mechanical hyperalgesia in mice

NeuroReport

Volumn 26, Issue 3, 2015, Pages 173-178

  Watanabe, Masaya ^a   Ueda, Takashi ^a   Shibata, Yasuhiro ^a   Kumamoto, Natsuko ^a   Ugawa, Shinya ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Capsaicin; Capsazepine; Carrageenan induced mechanical hyperalgesia; Primary hyperalgesia; Secondary hyperalgesia; Transient receptor potential vanilloid type 1

Indexed keywords

CAPSAICIN; CAPSAZEPINE; CARRAGEENAN; VANILLOID RECEPTOR 1; AGENTS ACTING ON THE PERIPHERAL NERVOUS AND NEUROMUSCULAR SYSTEMS; ANALGESIC AGENT; TRPV1 PROTEIN, MOUSE; VANILLOID RECEPTOR;

ADULT; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; HYPERALGESIA; INTRAPLANTAR DRUG ADMINISTRATION; KNOCKOUT MOUSE; MALE; MECHANICAL STIMULATION; MOUSE; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; WILD TYPE; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; COMPLICATION; DISEASE MODEL; GENETICS; HEMISPHERIC DOMINANCE; INFLAMMATION; METABOLISM; TOUCH;

ANALGESICS; ANIMALS; CAPSAICIN; CARRAGEENAN; DISEASE MODELS, ANIMAL; FUNCTIONAL LATERALITY; HYPERALGESIA; INFLAMMATION; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; SENSORY SYSTEM AGENTS; TOUCH; TRPV CATION CHANNELS;

EID: 84926113213     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0000000000000322     Document Type: Article

References (24)

1. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997;389:816-824.
2. Palazzo E, Luongo L, De Novellis V, Rossi F, Marabese I, Maione S. Transient receptor potential vanilloid type 1 and pain development. Curr Opin Pharmacol 2012;12:9-17.
3. Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Petersen-Zeitz KR, et al. Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 2000;288:306-313.
4. Bolcskei K, Helyes Z, Szabo A, Sandor K, Elekes K, Nemeth J, et al. Investigation of the role of TRPV1 receptors in acute and chronic nociceptive processes using gene-deficient mice. Pain 2005;117:368-376.
5. Pomonis JD, Harrison JE, Mark L, Bristol DR, Valenzano KJ, Walker K. N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl) tetrahydropyrazine-1 (2H) - carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. In vivo characterization in rat models of inflammatory and neuropathic pain. J Pharmacol Exp Ther 2003;306:387-393.
6. Walker KM, Urban L, Medhurst SJ, Patel S, Panesar M, Fox AJ, McIntyre P. The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain. J Pharmacol Exp Ther 2003;304:56-62.
7. Tang L, Chen Y, Chen Z, Blumberg PM, Kozikowski AP, Wang ZJ. Antinociceptive pharmacology of N-(4-chlorobenzyl)-N'-(4-hydroxy-3-iodo-5-methoxybenzyl) thiourea, a high-affinity competitive antagonist of the transient receptor potential vanilloid 1 receptor. J Pharmacol Exp Ther 2007;321:791-798.
8. Jang JH, Kim KH, Nam TS, Lee WT, Park KA, Kim DW, Leem JW. The role of uninjured C-afferents and injured afferents in the generation of mechanical hypersensitivity after partial peripheral nerve injury in the rat. Exp Neurol 2007;204:288-298.
9. Kim SM, Kim J, Kim E, Hwang SJ, Shin HK, Lee SE. Local application of capsaicin alleviates mechanical hyperalgesia after spinal nerve transection. Neurosci Lett 2008;433:199-204.
10. Smith H, Brooks JR. Capsaicin-based therapies for pain control. Prog Drug Res 2014;68:129-146.
11. Costa RM, Liu L, Nicolelis MA, Simon SA. Gustatory effects of capsaicin that are independent of TRPV1 receptors. Chem Senses 2005;30: (Suppl 1):i198-i200.
12. Yang R, Xiong Z, Liu C, Liu L. Inhibitory effects of capsaicin on voltage-gated potassium channels by TRPV1-independent pathway. Cell Mol Neurobiol 2014;34:565-576.
13. Yamada T, Ugawa S, Ueda T, Ishida Y, Kajita K, Shimada S. Differential localizations of the transient receptor potential channels TRPV4 and TRPV1 in the mouse urinary bladder. J Histochem Cytochem 2009;57:277-287.
14. Kissin I, Lee SS, Bradley EL Jr. Effect of prolonged nerve block on inflammatory hyperalgesia in rats: prevention of late hyperalgesia. Anesthesiology 1998;88:224-232.
15. Schreiber KL, Beitz AJ, Wilcox GL. Activation of spinal microglia in a murine model of peripheral inflammation-induced, long-lasting contralateral allodynia. Neurosci Lett 2008;440:63-67.
16. Btesh J, Fischer MJ, Stott K, McNaughton PA. Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia. J Neurosci 2013;33:9184-9193.
17. Menendez L, Lastra A, Hidalgo A, Baamonde A. The analgesic effect induced by capsaicin is enhanced in inflammatory states. Life Sci 2004;74:3235-3244.
18. Flynn R, Chapman K, Iftinca M, Aboushousha R, Varela D, Altier C. Targeting the transient receptor potential vanilloid type 1 (TRPV1) assembly domain attenuates inflammation-induced hypersensitivity. J Biol Chem 2014;289:16675-16687.
19. Shenker NG, Haigh RC, Mapp PI, Harris N, Blake DR. Contralateral hyperalgesia and allodynia following intradermal capsaicin injection in man. Rheumatology (Oxford) 2008;47:1417-1421.
20. Urban MO, Gebhart GF. Supraspinal contributions to hyperalgesia. Proc Natl Acad Sci USA 1999;96:7687-7692.
21. Cui M, Honore P, Zhong C, Gauvin D, Mikusa J, Hernandez G, et al. TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists. J Neurosci 2006;26:9385-9393.
22. Kim YH, Back SK, Davies AJ, Jeong H, Jo HJ, Chung G, et al. TRPV1 in GABAergic interneurons mediates neuropathic mechanical allodynia and disinhibition of the nociceptive circuitry in the spinal cord. Neuron 2012;74:640-647.
23. Magerl W, Fuchs PN, Meyer RA, Treede RD. Roles of capsaicin-insensitive nociceptors in cutaneous pain and secondary hyperalgesia. Brain 2001;124(Pt 9):1754-1764.
24. Szolcsanyi J, Pinter E. Transient receptor potential vanilloid 1 as a therapeutic target in analgesia. Expert Opin Ther Targets 2013;17:641-657.