Genetic polymorphisms of CXCR5 and CXCL13 are associated with non-responsiveness to the hepatitis B vaccine

Vaccine

Volumn 32, Issue 41, 2014, Pages 5316-5322

  Duan, Zhaojun ^a   Chen, Xiangmei ^a   Liang, Zhenglun ^b   Zeng, Ying ^c   Zhu, Fengcai ^d   Long, Lu ^a   McCrae, Malcolm A ^e   Zhuang, Hui ^a   Shen, Tao ^a   Lu, Fengmin ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b NATIONAL INSTITUTES FOR FOOD AND DRUG CONTROL   (China)

^c Shenzhen Weiguang Biological Products Co Ltd   (China)

^d JIANGSU PROVINCIAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^e INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

CXCL13; CXCR5; Follicular T helper cell; Hepatitis B vaccine; Non response; Polymorphism

Indexed keywords

CHEMOKINE RECEPTOR CXCR5; CXCL13 CHEMOKINE; HEPATITIS B VACCINE; CXCL13 PROTEIN, HUMAN; CXCR5 PROTEIN, HUMAN;

ADULT; ALLELE; ARTICLE; B LYMPHOCYTE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENOTYPE; HAN CHINESE; HAPLOTYPE; HELPER CELL; HEPATITIS B; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOPHARMACOLOGY; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT RESPONSE; VACCINATION; GENETICS; IMMUNOLOGY; MIDDLE AGED; TREATMENT FAILURE;

ADULT; CHEMOKINE CXCL13; FEMALE; GENOTYPE; HAPLOTYPES; HEPATITIS B VACCINES; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CXCR5; T-LYMPHOCYTES, HELPER-INDUCER; TREATMENT FAILURE;

EID: 84925884897     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.07.064     Document Type: Article

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