A novel triple repeat mutant Tau transgenic model that mimics aspects of Pick's disease and fronto-temporal tauopathies

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Rockenstein, Edward ^a   Overk, Cassia R ^a   Ubhi, Kiren ^a   Mante, Michael ^a   Patrick, Christina ^a   Adame, Anthony ^a   Bisquert, Alejandro ^a   Trejo Morales, Margarita ^a   Spencer, Brian ^a   Masliah, Eliezer ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TAU PROTEIN; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARGYROPHILIA; ARTICLE; ASTROCYTOSIS; BIOACCUMULATION; CONTROLLED STUDY; DENTATE GYRUS; DISEASE COURSE; EMBRYO; FRONTAL CORTEX; GENE MUTATION; GRANULE CELL; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; HYPERACTIVITY; LIMBIC SYSTEM; MEMORY DISORDER; MOUSE; MUTANT; NEOCORTEX; NERVE DEGENERATION; NEURITE; NEUROPATHOLOGY; NONHUMAN; PERIKARYON; PICK PRESENILE DEMENTIA; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PYRAMIDAL NERVE CELL; TAUOPATHY; TEMPORAL CORTEX; TRINUCLEOTIDE REPEAT; AMINO ACID SEQUENCE; ANIMAL; ANIMAL BEHAVIOR; AXON; CHEMISTRY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; HIPPOCAMPUS; HUMAN; INTERMEDIATE FILAMENT; MEMORY; METABOLISM; MITOCHONDRION; PATHOLOGY; PATHOPHYSIOLOGY; PROTEIN TRANSPORT; TIME FACTOR; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS;

ANIMALS; AXONS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HUMANS; INTERMEDIATE FILAMENTS; MEMORY; MICE; MICE, TRANSGENIC; MITOCHONDRIA; NEOCORTEX; PICK DISEASE OF THE BRAIN; PROTEIN TRANSPORT; REPETITIVE SEQUENCES, AMINO ACID; RNA, MESSENGER; TAU PROTEINS; TAUOPATHIES; TIME FACTORS;

EID: 84925880040     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0121570     Document Type: Article

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