Acetylated chitosan oligosaccharides act as antagonists against glutamate-induced PC12 cell death via Bcl-2/Bax signal pathway

Marine Drugs

Volumn 13, Issue 3, 2015, Pages 1267-1289

  Hao, Cui ^a   Gao, Lixia ^a   Zhang, Yiran ^a   Wang, Wei ^a   Yu, Guangli ^a   Guan, Huashi ^a   Zhang, Lijuan ^a   Li, Chunxia ^a  

^a OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

Apoptosis; Mitochondrial membrane potential; Neuroprotective; PC12; Peracetylated chitosan oligosaccharide; Reactive oxygen species

Indexed keywords

CASPASE 3; CHITOSAN DERIVATIVE; GLUCOSAMINE; GLUTAMIC ACID; LACTATE DEHYDROGENASE; OLIGOSACCHARIDE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; CHITOSAN; NEUROPROTECTIVE AGENT;

ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; CARBON NUCLEAR MAGNETIC RESONANCE; CELL DEATH; CELL VIABILITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; DEACETYLATION; DEPOLYMERIZATION; DRUG INDUCED DISEASE; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVATION; GLUTAMATE INDUCED NEURAL CELL DEATH; HYDROLYSIS; MASS SPECTROMETRY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR MECHANICS; NEUROPROTECTION; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PC12 CELL LINE; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; ACETYLATION; ANIMAL; CHEMISTRY; DRUG EFFECTS; METABOLISM; RAT; SIGNAL TRANSDUCTION;

ACETYLATION; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL DEATH; CHITOSAN; GLUTAMIC ACID; MEMBRANE POTENTIAL, MITOCHONDRIAL; NEUROPROTECTIVE AGENTS; OLIGOSACCHARIDES; PC12 CELLS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84925878913     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md13031267     Document Type: Article

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