Chitooligosaccharides suppress the level of protein expression and acetylcholinesterase activity induced by Aβ25-35 in PC12 cells

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 3, 2009, Pages 860-862

  Lee, Sang Hoon ^a   Park, Jin Sook ^a   Kim, Se Kwon ^a   Ahn, Chang Bum ^b   Je, Jae Young ^b  

^a Pukyong National University   (South Korea)

^b Chonnam National University   (South Korea)

Author keywords

Amyloid peptide; Acetylcholinesterase; Chitooligosaccahride; Inhibition

Indexed keywords

ACETYLCHOLINESTERASE; AMYLOID BETA PROTEIN[25-35]; CHITOOLIGOSACCHARIDE DERIVATIVE; CHOLINESTERASE INHIBITOR; OLIGOSACCHARIDE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; DEACETYLATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; MOLECULAR WEIGHT; NONHUMAN; PROTEIN EXPRESSION; RAT;

ACETYLCHOLINESTERASE; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; CELL LINE; CHEMISTRY, PHARMACEUTICAL; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; OLIGOSACCHARIDES; PC12 CELLS; PEPTIDE FRAGMENTS; RATS;

EID: 58549103282     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.12.019     Document Type: Article

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