메뉴 건너뛰기




Volumn 29, Issue , 2010, Pages 12-22

Mitochondria as source of free radicals

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84925843679     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1159/000319933     Document Type: Chapter
Times cited : (9)

References (62)
  • 1
    • 0001590580 scopus 로고    scopus 로고
    • Free radicals, other reactive species and disease
    • Halliwell B, Gutterridge JMC (eds), Oxford, Oxford University Press
    • Halliwell B, Gutterridge JMC: Free radicals, other reactive species and disease; in Halliwell B, Gutterridge JMC (eds): Free Radicals in Biology and Medicine. Oxford, Oxford University Press, 1999, pp 617-784.
    • (1999) Free Radicals in Biology and Medicine , pp. 617-784
    • Halliwell, B.1    Gutterridge, J.M.C.2
  • 2
    • 0002143021 scopus 로고    scopus 로고
    • Ageing, nutrition, disease and therapy: a role for antioxidants?
    • Halliwell B, Gutterridge JMC (eds), Oxford, Oxford University Press
    • Halliwell B, Gutterridge JMC: Ageing, nutrition, disease and therapy: a role for antioxidants? in Halliwell B, Gutterridge JMC (eds): Free Radicals in Biology and Medicine. Oxford, Oxford University Press, 1999, pp 784-859.
    • (1999) Free Radicals in Biology and Medicine , pp. 784-859
    • Halliwell, B.1    Gutterridge, J.M.C.2
  • 3
    • 0037444553 scopus 로고    scopus 로고
    • In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy
    • McLellan ME, Kajdasz ST, Hyman BT, Bacskai BJ:In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy. J Neurosci 2003;23:2212-2217.
    • (2003) J Neurosci , vol.23 , pp. 2212-2217
    • McLellan, M.E.1    Kajdasz, S.T.2    Hyman, B.T.3    Bacskai, B.J.4
  • 5
    • 0038051345 scopus 로고    scopus 로고
    • Mitochondria, oxidative damage, and inflammation in Parkinson's disease
    • Beal MF: Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Ann NY Acad Sci 2003;991:120-131.
    • (2003) Ann NY Acad Sci , vol.991 , pp. 120-131
    • Beal, M.F.1
  • 6
    • 0041430614 scopus 로고    scopus 로고
    • Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease
    • Hoglinger GU, Carrard G, Michel PP, Medja F, Lombes A, Ruberg M, Friguet B, Hirsch EC:Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease. J Neurochem 2003;86:1297-1307.
    • (2003) J Neurochem , vol.86 , pp. 1297-1307
    • Hoglinger, G.U.1    Carrard, G.2    Michel, P.P.3    Medja, F.4    Lombes, A.5    Ruberg, M.6    Friguet, B.7    Hirsch, E.C.8
  • 7
    • 0036321382 scopus 로고    scopus 로고
    • Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients
    • Wiedemann FR, Manfredi G, Mawrin C, Beal MF, Schon EA: Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients. J Neurochem 2002;80:616-625.
    • (2002) J Neurochem , vol.80 , pp. 616-625
    • Wiedemann, F.R.1    Manfredi, G.2    Mawrin, C.3    Beal, M.F.4    Schon, E.A.5
  • 8
    • 33847615655 scopus 로고    scopus 로고
    • Why is superoxide cytotoxic?
    • Halliwell B, Gutterridge JMC (eds), Oxford, Oxford University Press
    • Halliwell B, Gutterridge JMC: Why is superoxide cytotoxic?; in Halliwell B, Gutterridge JMC (eds):Free Radicals in Biology and Medicine. Oxford, Oxford University Press, 1999, pp 129-134.
    • (1999) Free Radicals in Biology and Medicine , pp. 129-134
    • Halliwell, B.1    Gutterridge, J.M.C.2
  • 9
    • 0014691242 scopus 로고
    • Superoxide dismutase An enzymic function for erythrocuprein (hemocuprein).
    • McCord JM, Fridovich I: Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 1969;244:6049-6055.
    • (1969) J Biol Chem , vol.244 , pp. 6049-6055
    • McCord, J.M.1    Fridovich, I.2
  • 10
    • 0015694842 scopus 로고
    • Mitochondrial superoxide dismutase
    • Weisiger RA, Fridovich I: Mitochondrial superoxide dismutase. J Biol Chem 1973;248:4793-4796.
    • (1973) J Biol Chem , vol.248 , pp. 4793-4796
    • Weisiger, R.A.1    Fridovich, I.2
  • 12
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer RM, Ferrige AG, Moncada S: Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987;327:524-526.
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 13
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide
    • Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA: Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci U S A 1990;87:1620-1624.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 14
    • 84925868479 scopus 로고    scopus 로고
    • http://nobelprize.org/nobel_prizes/medicine/laureates/1998/.
  • 15
    • 15844404722 scopus 로고    scopus 로고
    • Biochemistry: a pore way to die
    • Halestrap A: Biochemistry: a pore way to die. Nature 2005;434:578-579.
    • (2005) Nature , vol.434 , pp. 578-579
    • Halestrap, A.1
  • 16
    • 0015383455 scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239-257.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 17
    • 2542505678 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial DNA mutations in human aging
    • Wei YH: Oxidative stress and mitochondrial DNA mutations in human aging. Proc Soc Exp Biol Med 1998;217:53-63.
    • (1998) Proc Soc Exp Biol Med , vol.217 , pp. 53-63
    • Wei, Y.H.1
  • 18
    • 0024541837 scopus 로고
    • Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
    • Linnane AW, Marzuki S, Ozawa T, Tanaka M:Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet 1989;333:642-645.
    • (1989) Lancet , vol.333 , pp. 642-645
    • Linnane, A.W.1    Marzuki, S.2    Ozawa, T.3    Tanaka, M.4
  • 19
    • 0031205455 scopus 로고    scopus 로고
    • Mitochondrial DNA in aging and disease
    • Wallace DC: Mitochondrial DNA in aging and disease. Sci Am 1997;277:40-47.
    • (1997) Sci Am , vol.277 , pp. 40-47
    • Wallace, D.C.1
  • 20
    • 0016681098 scopus 로고
    • Mitochondrial production of superoxide anions and its relationship to the antimycin insensitive respiration
    • Boveris A, Cadenas E: Mitochondrial production of superoxide anions and its relationship to the antimycin insensitive respiration. FEBS Lett 1975;1:311-314.
    • (1975) FEBS Lett , vol.1 , pp. 311-314
    • Boveris, A.1    Cadenas, E.2
  • 21
    • 0018393931 scopus 로고
    • NADH-and NADPHdependent formation of superoxide anions by bovine heart submitochondrial particles and NADH-ubiquinone reductase preparation
    • Takeshige K, Minakami S: NADH-and NADPHdependent formation of superoxide anions by bovine heart submitochondrial particles and NADH-ubiquinone reductase preparation. Biochem J 1979;180:129-135.
    • (1979) Biochem J , vol.180 , pp. 129-135
    • Takeshige, K.1    Minakami, S.2
  • 23
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts:requirement for dATP and cytochrome c
    • Liu X, Kim CN, Yang J, Jemmerson R, Wang X:Induction of apoptotic program in cell-free extracts:requirement for dATP and cytochrome c. Cell 1996; 86:147-157.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 25
    • 0032478694 scopus 로고    scopus 로고
    • Prevention of mitochondrial injury by manganese superoxide dismutase reveals a primary mechanism for alkalineinduced cell death
    • Majima H, Oberley TD, Furukawa K, Mattson MP, Yen H-C, Szweda LI, St Clair DK: Prevention of mitochondrial injury by manganese superoxide dismutase reveals a primary mechanism for alkalineinduced cell death. J Biol Chem 1998;273:8217-8224.
    • (1998) J Biol Chem , vol.273 , pp. 8217-8224
    • Majima, H.1    Oberley, T.D.2    Furukawa, K.3    Mattson, M.P.4    Yen, H.-C.5    Szweda, L.I.6    St Clair, D.K.7
  • 27
    • 0033582533 scopus 로고    scopus 로고
    • Mitochondrial phospholipid hydroperoxide glutathione peroxidase plays a major role in preventing oxidative injury to cells
    • Arai M, Imai H, Koumura T, Yoshida M, Emoto K, Umeda M, Chiba N, Nakagawa Y: Mitochondrial phospholipid hydroperoxide glutathione peroxidase plays a major role in preventing oxidative injury to cells. J Biol Chem 1999;274:4924-4933.
    • (1999) J Biol Chem , vol.274 , pp. 4924-4933
    • Arai, M.1    Imai, H.2    Koumura, T.3    Yoshida, M.4    Emoto, K.5    Umeda, M.6    Chiba, N.7    Nakagawa, Y.8
  • 30
    • 0032910361 scopus 로고    scopus 로고
    • Mitochondrial regulation of cell death:mitochondria are essential for procaspase 3-p21 complex formation to resist Fas-mediated cell death
    • Suzuki A, Tsutomi Y, Yamamoto N, Shibutani T, Akahane K: Mitochondrial regulation of cell death:mitochondria are essential for procaspase 3-p21 complex formation to resist Fas-mediated cell death. Mol Cell Biol 1999;19:3842-3847.
    • (1999) Mol Cell Biol , vol.19 , pp. 3842-3847
    • Suzuki, A.1    Tsutomi, Y.2    Yamamoto, N.3    Shibutani, T.4    Akahane, K.5
  • 31
    • 0033525788 scopus 로고    scopus 로고
    • Mitochondrial evolution
    • Gray MW, Burger G, Lang BF: Mitochondrial evolution. Science 1999;283:1476-1481.
    • (1999) Science , vol.283 , pp. 1476-1481
    • Gray, M.W.1    Burger, G.2    Lang, B.F.3
  • 32
    • 78751486387 scopus 로고    scopus 로고
    • Oxidation of glucose yields 31 ATP molecules assuming the 'modern' P/O ratios of 2.5 for NADH and 1.5 for FADH2
    • Salway JG (ed), Malden, Blackwell Publishing
    • Salway JG: Oxidation of glucose yields 31 ATP molecules assuming the 'modern' P/O ratios of 2.5 for NADH and 1.5 for FADH2, in Salway JG (ed):Metabolism at a Glance. Malden, Blackwell Publishing, 2004, pp 21.
    • (2004) Metabolism at a Glance , pp. 21
    • Salway, J.G.1
  • 33
    • 0026879664 scopus 로고
    • An analysis of the role of coenzyme Q in free radical generation and as an antioxidant
    • Beyer RE: An analysis of the role of coenzyme Q in free radical generation and as an antioxidant. Biochem Cell Biol 1992;70:390-403.
    • (1992) Biochem Cell Biol , vol.70 , pp. 390-403
    • Beyer, R.E.1
  • 34
    • 0015882341 scopus 로고
    • The mitochondrial generation of hydrogen peroxide General properties and effect of hyperbaric oxygen.
    • Boveris A, Chance B: The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 1973;134:707-716.
    • (1973) Biochem J , vol.134 , pp. 707-716
    • Boveris, A.1    Chance, B.2
  • 36
    • 33847638029 scopus 로고
    • Two b cytochromes of pigeon heart mitochondria
    • Sato N, Wilson DF, Chance B: Two b cytochromes of pigeon heart mitochondria. FEBS Lett 1971;15:209-212.
    • (1971) FEBS Lett , vol.15 , pp. 209-212
    • Sato, N.1    Wilson, D.F.2    Chance, B.3
  • 38
    • 0025756918 scopus 로고
    • Enzymic mechanisms of superoxide production
    • Cross AR, Jones OT: Enzymic mechanisms of superoxide production. Biochim Biophys Acta 1991;1057:281-298.
    • (1991) Biochim Biophys Acta , vol.1057 , pp. 281-298
    • Cross, A.R.1    Jones, O.T.2
  • 39
    • 0035930395 scopus 로고    scopus 로고
    • Vitamin E succinate protects hepatocytes against the toxic effect of reactive oxygen species generated at mitochondrial complexes I and III by alkylating agents
    • Zhang JG, Nicholls-Grzemski FA, Tirmenstein MA, Fariss MW: Vitamin E succinate protects hepatocytes against the toxic effect of reactive oxygen species generated at mitochondrial complexes I and III by alkylating agents. Chem Biol Interact 2001;138:267-284.
    • (2001) Chem Biol Interact , vol.138 , pp. 267-284
    • Zhang, J.G.1    Nicholls-Grzemski, F.A.2    Tirmenstein, M.A.3    Fariss, M.W.4
  • 40
    • 0035816639 scopus 로고    scopus 로고
    • Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A
    • Yamagishi S, Edelstein D, Du X, Kaneda Y, Guzman M, Brownlee M: Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. J Biol Chem 2001;276:25096-25100.
    • (2001) J Biol Chem , vol.276 , pp. 25096-25100
    • Yamagishi, S.1    Edelstein, D.2    Du, X.3    Kaneda, Y.4    Guzman, M.5    Brownlee, M.6
  • 41
    • 10344221083 scopus 로고    scopus 로고
    • Complex III releases superoxide to both sides of the inner mitochondrial membrane
    • Muller FL, Liu Y, Van Remmen H: Complex III releases superoxide to both sides of the inner mitochondrial membrane. J Biol Chem 2004;279:49064-49073.
    • (2004) J Biol Chem , vol.279 , pp. 49064-49073
    • Muller, F.L.1    Liu, Y.2    Van Remmen, H.3
  • 42
    • 0037474309 scopus 로고    scopus 로고
    • Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species
    • Setsukinai K, Urano Y, Kakinuma K, Majima HJ, Nagano T: Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species. J Biol Chem 2003;278:3170-3175.
    • (2003) J Biol Chem , vol.278 , pp. 3170-3175
    • Setsukinai, K.1    Urano, Y.2    Kakinuma, K.3    Majima, H.J.4    Nagano, T.5
  • 43
    • 4544322045 scopus 로고    scopus 로고
    • Free radicals and aging
    • Barja G: Free radicals and aging. Trends Neurosci 2004;27:595-600.
    • (2004) Trends Neurosci , vol.27 , pp. 595-600
    • Barja, G.1
  • 45
    • 0027055332 scopus 로고
    • Ageassociated oxygen damage and mutations in mitochondrial DNA in human hearts
    • Hayakawa M, Hattori K, Sugiyama S, Ozawa T: Ageassociated oxygen damage and mutations in mitochondrial DNA in human hearts. Biochem Biophys Res Commun 1992;189:979-985.
    • (1992) Biochem Biophys Res Commun , vol.189 , pp. 979-985
    • Hayakawa, M.1    Hattori, K.2    Sugiyama, S.3    Ozawa, T.4
  • 47
    • 0030923869 scopus 로고    scopus 로고
    • Calcium homeostasis and reactive oxygen species production in cells transformed by mitochondria from individuals with sporadic Alzheimer's disease
    • Sheehan JP, Swerdlow RH, Miller SW, Davis RE, Parks JK, Parker WD, Tuttle JB: Calcium homeostasis and reactive oxygen species production in cells transformed by mitochondria from individuals with sporadic Alzheimer's disease. J Neurosci 1997;17:4612-4622.
    • (1997) J Neurosci , vol.17 , pp. 4612-4622
    • Sheehan, J.P.1    Swerdlow, R.H.2    Miller, S.W.3    Davis, R.E.4    Parks, J.K.5    Parker, W.D.6    Tuttle, J.B.7
  • 48
    • 0018776894 scopus 로고
    • Hydroperoxide metabolism in mammalian organs
    • Chance B, Sies H, Boveris A: Hydroperoxide metabolism in mammalian organs. Physiol Rev 1979;59:527-605.
    • (1979) Physiol Rev , vol.59 , pp. 527-605
    • Chance, B.1    Sies, H.2    Boveris, A.3
  • 49
    • 0036903625 scopus 로고    scopus 로고
    • Complex I-mediated reactive oxygen species generation:modulation by cytochrome c and NAD(P)+ oxidation-reduction state
    • Kushnareva Y, Murphy AN, Andreyev A: Complex I-mediated reactive oxygen species generation:modulation by cytochrome c and NAD(P)+ oxidation-reduction state. Biochem J 2002;368:545-553.
    • (2002) Biochem J , vol.368 , pp. 545-553
    • Kushnareva, Y.1    Murphy, A.N.2    Andreyev, A.3
  • 50
    • 0141815741 scopus 로고    scopus 로고
    • Production of reactive oxygen species by mitochondria: central role of complex III
    • Chen Q, Vazquez EJ, Moghaddas S, Hoppel CL, Lesnefsky EJ: Production of reactive oxygen species by mitochondria: central role of complex III. J Biol Chem 2003;278:36027-36031.
    • (2003) J Biol Chem , vol.278 , pp. 36027-36031
    • Chen, Q.1    Vazquez, E.J.2    Moghaddas, S.3    Hoppel, C.L.4    Lesnefsky, E.J.5
  • 51
    • 25844520458 scopus 로고    scopus 로고
    • Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism
    • Jezek P, Hlavata L: Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism. Int J Biochem Cell Biol 2005;37:2478-2503.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 2478-2503
    • Jezek, P.1    Hlavata, L.2
  • 52
    • 0027426263 scopus 로고
    • Absence of electron transport (Rho0 state) restores growth of a manganese-superoxide dismutase-deficient Saccharomyces cerevisiae in hyperoxia Evidence for electron transport as a major source of superoxide generation in vivo.
    • Guidot DM, McCord JM, Wright RM, Repine JE:Absence of electron transport (Rho0 state) restores growth of a manganese-superoxide dismutase-deficient Saccharomyces cerevisiae in hyperoxia. Evidence for electron transport as a major source of superoxide generation in vivo. J Biol Chem 1993;268:26699-26703.
    • (1993) J Biol Chem , vol.268 , pp. 26699-26703
    • Guidot, D.M.1    McCord, J.M.2    Wright, R.M.3    Repine, J.E.4
  • 53
    • 24144464489 scopus 로고    scopus 로고
    • Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources
    • Adam-Vizi V: Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources. Antioxid Redox Signal 2005;7:1140-1149.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1140-1149
    • Adam-Vizi, V.1
  • 54
    • 0027087413 scopus 로고
    • Structural and functional mitochondrial abnormalities associated with high levels of partially deleted mitochondrial DNAs in somatic cell hybrids
    • Sancho S, Moraes CT, Tanji K, Miranda AF:Structural and functional mitochondrial abnormalities associated with high levels of partially deleted mitochondrial DNAs in somatic cell hybrids. Somat Cell Mol Genet 1992;18:431-442.
    • (1992) Somat Cell Mol Genet , vol.18 , pp. 431-442
    • Sancho, S.1    Moraes, C.T.2    Tanji, K.3    Miranda, A.F.4
  • 55
    • 0033614441 scopus 로고    scopus 로고
    • Oxidative stress and upregulation of mitochondrial biogenesis genes in mitochondrial DNA-depleted HeLa cells
    • Miranda S, Foncea R, Guerrero J, Leighton F:Oxidative stress and upregulation of mitochondrial biogenesis genes in mitochondrial DNA-depleted HeLa cells. Biochem Biophys Res Commun 1999; 258:44-49.
    • (1999) Biochem Biophys Res Commun , vol.258 , pp. 44-49
    • Miranda, S.1    Foncea, R.2    Guerrero, J.3    Leighton, F.4
  • 57
    • 0025309791 scopus 로고
    • Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?
    • Bandy B, Davison AJ: Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? Free Radic Biol Med 1990;8:523-539.
    • (1990) Free Radic Biol Med , vol.8 , pp. 523-539
    • Bandy, B.1    Davison, A.J.2
  • 58
    • 29344444706 scopus 로고    scopus 로고
    • Visualizing common deletion of mitochondrial DNA-augmented mitochondrial reactive oxygen species generation and apoptosis upon oxidative stress
    • Peng T-I, Yu P-R, Chen J-Y, Wang H-L, Wu H-Y, Wei Y-H, Jou M-J: Visualizing common deletion of mitochondrial DNA-augmented mitochondrial reactive oxygen species generation and apoptosis upon oxidative stress. Biochim Biophys Acta 2006; 1762:241-255.
    • (2006) Biochim Biophys Acta , vol.1762 , pp. 241-255
    • Peng, T.-I.1    Yu, P.-R.2    Chen, J.-Y.3    Wang, H.-L.4    Wu, H.-Y.5    Wei, Y.-H.6    Jou, M.-J.7
  • 59
    • 0034329742 scopus 로고    scopus 로고
    • Apoptosis in neurodegenerative disorders
    • Mattson MP: Apoptosis in neurodegenerative disorders. Nat Rev Mol Cell Biol 2000;1:120-129.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 120-129
    • Mattson, M.P.1
  • 60
  • 61
    • 0035878691 scopus 로고    scopus 로고
    • Overexpression of mitochondrial manganese superoxide dismutase protects against radiation-induced cell death in the human hepatocellular carcinoma cell line, HLE
    • Motoori S, Majima HJ, Ebara M, Kato H, Hirai F, Kakinuma S, Yamaguchi C, Ozawa T, Nagano T, Tsujii H, Saisho H: Overexpression of mitochondrial manganese superoxide dismutase protects against radiation-induced cell death in the human hepatocellular carcinoma cell line, HLE. Cancer Res 2001;61:5382-5388.
    • (2001) Cancer Res , vol.61 , pp. 5382-5388
    • Motoori, S.1    Majima, H.J.2    Ebara, M.3    Kato, H.4    Hirai, F.5    Kakinuma, S.6    Yamaguchi, C.7    Ozawa, T.8    Nagano, T.9    Tsujii, H.10    Saisho, H.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.