-
1
-
-
65249098267
-
Catalytic mechanism and assembly of the proteasome
-
Marques, A. J., Palanimurugan, R., Matias, A. C., Ramos, P. C. & Dohmen, R. J. Catalytic mechanism and assembly of the proteasome. Chem. Rev. 109, 1509-1536 (2009).
-
(2009)
Chem. Rev.
, vol.109
, pp. 1509-1536
-
-
Marques, A.J.1
Palanimurugan, R.2
Matias, A.C.3
Ramos, P.C.4
Dohmen, R.J.5
-
2
-
-
50849123778
-
PACemakers of proteasome core particle assembly
-
Ramos, P. C. & Dohmen, R. J. PACemakers of proteasome core particle assembly. Structure 16, 1296-1304 (2008).
-
(2008)
Structure
, vol.16
, pp. 1296-1304
-
-
Ramos, P.C.1
Dohmen, R.J.2
-
3
-
-
40949117574
-
A multimeric assembly factor controls the formation of alternative 20S proteasomes
-
Kusmierczyk, A. R., Kunjappu, M. J., Funakoshi, M. & Hochstrasser, M. A multimeric assembly factor controls the formation of alternative 20S proteasomes. Nat. Struct. Mol. Biol. 15, 237-244 (2008).
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 237-244
-
-
Kusmierczyk, A.R.1
Kunjappu, M.J.2
Funakoshi, M.3
Hochstrasser, M.4
-
4
-
-
40949120953
-
Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes
-
Yashiroda, H. et al. Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes. Nat. Struct. Mol. Biol. 15, 228-236 (2008).
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 228-236
-
-
Yashiroda, H.1
-
5
-
-
84905110181
-
Pba3-Pba4 heterodimer acts as a molecular matchmaker in proteasome alpha-ring formation
-
Takagi, K. et al. Pba3-Pba4 heterodimer acts as a molecular matchmaker in proteasome alpha-ring formation. Biochem. Biophys. Res. Commun. 450, 1110-1114 (2014).
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.450
, pp. 1110-1114
-
-
Takagi, K.1
-
6
-
-
0032548998
-
Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly
-
Ramos, P. C., Hockendorff, J., Johnson, E. S., Varshavsky, A. & Dohmen, R. J. Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92, 489-499 (1998).
-
(1998)
Cell
, vol.92
, pp. 489-499
-
-
Ramos, P.C.1
Hockendorff, J.2
Johnson, E.S.3
Varshavsky, A.4
Dohmen, R.J.5
-
7
-
-
85027955696
-
A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor binding
-
Kusmierczyk, A. R., Kunjappu, M. J., Kim, R. Y. & Hochstrasser, M. A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor binding. Nat. Struct. Mol. Biol. 18, 622-629 (2011).
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 622-629
-
-
Kusmierczyk, A.R.1
Kunjappu, M.J.2
Kim, R.Y.3
Hochstrasser, M.4
-
8
-
-
84868238774
-
Structure of a proteasome Pba1-Pba2 complex: Implications for proteasome assembly, activation, and biological function
-
Stadtmueller, B. M. et al. Structure of a proteasome Pba1-Pba2 complex: implications for proteasome assembly, activation, and biological function. J. Biol. Chem. 287, 37371-37382 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 37371-37382
-
-
Stadtmueller, B.M.1
-
9
-
-
27644554700
-
A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes
-
Hirano, Y. et al. A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes. Nature 437, 1381-1385 (2005).
-
(2005)
Nature
, vol.437
, pp. 1381-1385
-
-
Hirano, Y.1
-
10
-
-
84890203542
-
Regulation of proteasome activity in health and disease
-
Schmidt, M. & Finley, D. Regulation of proteasome activity in health and disease. Biochim. Biophys. Acta 1843, 13-25 (2014).
-
(2014)
Biochim. Biophys. Acta
, vol.1843
, pp. 13-25
-
-
Schmidt, M.1
Finley, D.2
-
11
-
-
84876916040
-
Structural biology of the proteasome
-
Kish-Trier, E. & Hill, C. P. Structural biology of the proteasome. Annu. Rev. Biophys. 42, 29-49 (2013).
-
(2013)
Annu. Rev. Biophys.
, vol.42
, pp. 29-49
-
-
Kish-Trier, E.1
Hill, C.P.2
-
12
-
-
77649243592
-
Structure of a Blm10 complex reveals common mechanisms for proteasome binding and gate opening
-
Sadre-Bazzaz, K., Whitby, F. G., Robinson, H., Formosa, T. & Hill, C. P. Structure of a Blm10 complex reveals common mechanisms for proteasome binding and gate opening. Mol. Cell 37, 728-735 (2010).
-
(2010)
Mol. Cell
, vol.37
, pp. 728-735
-
-
Sadre-Bazzaz, K.1
Whitby, F.G.2
Robinson, H.3
Formosa, T.4
Hill, C.P.5
-
13
-
-
84856976866
-
Complete subunit architecture of the proteasome regulatory particle
-
Lander, G. C. et al. Complete subunit architecture of the proteasome regulatory particle. Nature 482, 186-191 (2012).
-
(2012)
Nature
, vol.482
, pp. 186-191
-
-
Lander, G.C.1
-
14
-
-
84866269021
-
Near-atomic resolution structural model of the yeast 26S proteasome
-
Beck, F. et al. Near-atomic resolution structural model of the yeast 26S proteasome. Proc. Natl Acad. Sci. USA 109, 14870-14875 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 14870-14875
-
-
Beck, F.1
-
15
-
-
36849024844
-
The C-terminal extension of the beta7 subunit and activator complexes stabilize nascent 20S proteasomes and promote their maturation
-
Marques, A. J., Glanemann, C., Ramos, P. C. & Dohmen, R. J. The C-terminal extension of the beta7 subunit and activator complexes stabilize nascent 20S proteasomes and promote their maturation. J. Biol. Chem. 282, 34869-34876 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 34869-34876
-
-
Marques, A.J.1
Glanemann, C.2
Ramos, P.C.3
Dohmen, R.J.4
-
16
-
-
0242522904
-
Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly
-
Fehlker, M., Wendler, P., Lehmann, A. & Enenkel, C. Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly. EMBO Rep. 4, 959-963 (2003).
-
(2003)
EMBO Rep.
, vol.4
, pp. 959-963
-
-
Fehlker, M.1
Wendler, P.2
Lehmann, A.3
Enenkel, C.4
-
17
-
-
84885858648
-
Blm10 facilitates nuclear import of proteasome core particles
-
Weberruss, M. H. et al. Blm10 facilitates nuclear import of proteasome core particles. EMBO J. 32, 2697-2707 (2013).
-
(2013)
EMBO J.
, vol.32
, pp. 2697-2707
-
-
Weberruss, M.H.1
-
18
-
-
84899411254
-
Proteasomes associated with the Blm10 activator protein antagonize mitochondrial fission through degradation of the fission protein Dnm1
-
Tar, K. et al. Proteasomes associated with the Blm10 activator protein antagonize mitochondrial fission through degradation of the fission protein Dnm1. J. Biol. Chem. 289, 12145-12156 (2014).
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 12145-12156
-
-
Tar, K.1
-
19
-
-
83355169695
-
Blm10 protein promotes proteasomal substrate turnover by an active gating mechanism
-
Dange, T. et al. Blm10 protein promotes proteasomal substrate turnover by an active gating mechanism. J. Biol. Chem. 286, 42830-42839 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 42830-42839
-
-
Dange, T.1
-
20
-
-
84878314537
-
Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis
-
Qian, M. X. et al. Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis. Cell 153, 1012-1024 (2013).
-
(2013)
Cell
, vol.153
, pp. 1012-1024
-
-
Qian, M.X.1
-
21
-
-
84885428073
-
Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA + unfoldase
-
Beckwith, R., Estrin, E., Worden, E. J. & Martin, A. Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA + unfoldase. Nat. Struct. Mol. Biol. 20, 1164-1172 (2013).
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1164-1172
-
-
Beckwith, R.1
Estrin, E.2
Worden, E.J.3
Martin, A.4
-
22
-
-
57649140340
-
Differential roles of the COOH termini of AAA subunits of PA700 (19S regulator) in asymmetric assembly and activation of the 26S proteasome
-
Gillette, T. G., Kumar, B., Thompson, D., Slaughter, C. A. & DeMartino, G. N. Differential roles of the COOH termini of AAA subunits of PA700 (19S regulator) in asymmetric assembly and activation of the 26S proteasome. J. Biol. Chem. 283, 31813-31822 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 31813-31822
-
-
Gillette, T.G.1
Kumar, B.2
Thompson, D.3
Slaughter, C.A.4
DeMartino, G.N.5
-
23
-
-
34548274872
-
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry
-
Smith, D. M. et al. Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry. Mol. Cell 27, 731-744 (2007).
-
(2007)
Mol. Cell
, vol.27
, pp. 731-744
-
-
Smith, D.M.1
-
24
-
-
80555130924
-
An asymmetric interface between the regulatory and core particles of the proteasome
-
Tian, G. et al. An asymmetric interface between the regulatory and core particles of the proteasome. Nat. Struct. Mol. Biol. 18, 1259-1267 (2011).
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 1259-1267
-
-
Tian, G.1
-
25
-
-
34547838178
-
20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals
-
Le Tallec, B. et al. 20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals. Mol. Cell 27, 660-674 (2007).
-
(2007)
Mol. Cell
, vol.27
, pp. 660-674
-
-
Le Tallec, B.1
-
26
-
-
34247617365
-
beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint
-
Li, X., Kusmierczyk, A. R., Wong, P., Emili, A. & Hochstrasser, M. beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint. EMBO J. 26, 2339-2349 (2007).
-
(2007)
EMBO J.
, vol.26
, pp. 2339-2349
-
-
Li, X.1
Kusmierczyk, A.R.2
Wong, P.3
Emili, A.4
Hochstrasser, M.5
-
27
-
-
18744391955
-
The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle
-
Schmidt, M. et al. The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle. Nat. Struct. Mol. Biol. 12, 294-303 (2005).
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 294-303
-
-
Schmidt, M.1
-
28
-
-
84860181809
-
Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly
-
Barrault, M. B. et al. Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly. Proc. Natl Acad. Sci. USA 109, E1001-E1010 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. E1001-E1010
-
-
Barrault, M.B.1
-
29
-
-
80054703106
-
Loss of Rpt5 protein interactions with the core particle and Nas2 protein causes the formation of faulty proteasomes that are inhibited by Ecm29 protein
-
Lee, S. Y., De la Mota-Peynado, A. & Roelofs, J. Loss of Rpt5 protein interactions with the core particle and Nas2 protein causes the formation of faulty proteasomes that are inhibited by Ecm29 protein. J. Biol. Chem. 286, 36641-36651 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 36641-36651
-
-
Lee, S.Y.1
De La Mota-Peynado, A.2
Roelofs, J.3
-
30
-
-
84878131964
-
Reconfiguration of the proteasome during chaperone-mediated assembly
-
Park, S. et al. Reconfiguration of the proteasome during chaperone-mediated assembly. Nature 497, 512-516 (2013).
-
(2013)
Nature
, vol.497
, pp. 512-516
-
-
Park, S.1
-
31
-
-
67149112112
-
Chaperone-mediated pathway of proteasome regulatory particle assembly
-
Roelofs, J. et al. Chaperone-mediated pathway of proteasome regulatory particle assembly. Nature 459, 861-865 (2009).
-
(2009)
Nature
, vol.459
, pp. 861-865
-
-
Roelofs, J.1
-
32
-
-
67149121057
-
Hexameric assembly of the proteasomal ATPases is templated through their C termini
-
Park, S. et al. Hexameric assembly of the proteasomal ATPases is templated through their C termini. Nature 459, 866-870 (2009).
-
(2009)
Nature
, vol.459
, pp. 866-870
-
-
Park, S.1
-
33
-
-
84877575331
-
Conformational dynamics of the rpt6 ATPase in proteasome assembly and rpn14 binding
-
Ehlinger, A. et al. Conformational dynamics of the rpt6 ATPase in proteasome assembly and rpn14 binding. Structure 21, 753-765 (2013).
-
(2013)
Structure
, vol.21
, pp. 753-765
-
-
Ehlinger, A.1
-
34
-
-
84899918113
-
Structural basis for proteasome formation controlled by an assembly chaperone nas2
-
Satoh, T. et al. Structural basis for proteasome formation controlled by an assembly chaperone nas2. Structure 22, 731-743 (2014).
-
(2014)
Structure
, vol.22
, pp. 731-743
-
-
Satoh, T.1
-
35
-
-
84893364786
-
The mechanism for molecular assembly of the proteasome
-
Sahara, K., Kogleck, L., Yashiroda, H. & Murata, S. The mechanism for molecular assembly of the proteasome. Adv. Biol. Regul. 54, 51-58 (2014).
-
(2014)
Adv. Biol. Regul.
, vol.54
, pp. 51-58
-
-
Sahara, K.1
Kogleck, L.2
Yashiroda, H.3
Murata, S.4
-
37
-
-
0036296150
-
20S proteasomes are imported as precursor complexes into the nucleus of yeast
-
Lehmann, A., Janek, K., Braun, B., Kloetzel, P. M. & Enenkel, C. 20S proteasomes are imported as precursor complexes into the nucleus of yeast. J. Mol. Biol. 317, 401-413 (2002).
-
(2002)
J. Mol. Biol.
, vol.317
, pp. 401-413
-
-
Lehmann, A.1
Janek, K.2
Braun, B.3
Kloetzel, P.M.4
Enenkel, C.5
-
38
-
-
36849059755
-
Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites
-
Kleijnen, M. F. et al. Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites. Nat. Struct. Mol. Biol. 14, 1180-1188 (2007).
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 1180-1188
-
-
Kleijnen, M.F.1
-
39
-
-
0036753063
-
Multiple associated proteins regulate proteasome structure and function
-
Leggett, D. S. et al. Multiple associated proteins regulate proteasome structure and function. Mol. Cell 10, 495-507 (2002).
-
(2002)
Mol. Cell
, vol.10
, pp. 495-507
-
-
Leggett, D.S.1
-
40
-
-
84885586226
-
The proteasome-associated protein Ecm29 inhibits proteasomal ATPase activity and in vivo protein degradation by the proteasome
-
De La Mota-Peynado, A. et al. The proteasome-associated protein Ecm29 inhibits proteasomal ATPase activity and in vivo protein degradation by the proteasome. J. Biol. Chem. 288, 29467-29481 (2013).
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 29467-29481
-
-
De La Mota-Peynado, A.1
-
41
-
-
84903702716
-
Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding
-
Arciniega, M., Beck, P., Lange, O. F., Groll, M. & Huber, R. Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding. Proc. Natl Acad. Sci. USA 111, 9479-9484 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 9479-9484
-
-
Arciniega, M.1
Beck, P.2
Lange, O.F.3
Groll, M.4
Huber, R.5
-
42
-
-
68149164657
-
A tetrahedral transition state at the active sites of the 20S proteasome is coupled to opening of the alpha-ring channel
-
Osmulski, P. A., Hochstrasser, M. & Gaczynska, M. A tetrahedral transition state at the active sites of the 20S proteasome is coupled to opening of the alpha-ring channel. Structure 17, 1137-1147 (2009).
-
(2009)
Structure
, vol.17
, pp. 1137-1147
-
-
Osmulski, P.A.1
Hochstrasser, M.2
Gaczynska, M.3
-
43
-
-
49649088237
-
Functional and biochemical characterization of the 20S proteasome in a yeast temperature-sensitive mutant, rpt6-1
-
Chouduri, A. U., Tokumoto, T., Dohra, H., Ushimaru, T. & Yamada, S. Functional and biochemical characterization of the 20S proteasome in a yeast temperature-sensitive mutant, rpt6-1. BMC Biochem. 9, 20 (2008).
-
(2008)
BMC Biochem.
, vol.9
, pp. 20
-
-
Chouduri, A.U.1
Tokumoto, T.2
Dohra, H.3
Ushimaru, T.4
Yamada, S.5
-
44
-
-
84857131710
-
Optimizing ring assembly reveals the strength of weak interactions
-
Deeds, E. J., Bachman, J. A. & Fontana, W. Optimizing ring assembly reveals the strength of weak interactions. Proc. Natl Acad. Sci. USA 109, 2348-2353 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 2348-2353
-
-
Deeds, E.J.1
Bachman, J.A.2
Fontana, W.3
-
45
-
-
0031443249
-
Computer-based analysis of the binding steps in protein complex formation
-
Bray, D. & Lay, S. Computer-based analysis of the binding steps in protein complex formation. Proc. Natl Acad. Sci. USA 94, 13493-13498 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 13493-13498
-
-
Bray, D.1
Lay, S.2
-
46
-
-
33744821974
-
Stochastic dynamics of macromolecular-assembly networks
-
Saiz, L. & Vilar, J. M. Stochastic dynamics of macromolecular-assembly networks. Mol. Syst. Biol. 2, 2006.0024, 1-11 (2006).
-
(2006)
Mol. Syst. Biol.
, vol.2
-
-
Saiz, L.1
Vilar, J.M.2
-
47
-
-
54049107641
-
Some assembly required: Dedicated chaperones in eukaryotic proteasome biogenesis
-
Kusmierczyk, A. R. & Hochstrasser, M. Some assembly required: dedicated chaperones in eukaryotic proteasome biogenesis. Biol. Chem. 389, 1143-1151 (2008).
-
(2008)
Biol. Chem.
, vol.389
, pp. 1143-1151
-
-
Kusmierczyk, A.R.1
Hochstrasser, M.2
-
48
-
-
58849093135
-
Molecular mechanisms of proteasome assembly
-
Murata, S., Yashiroda, H. & Tanaka, K. Molecular mechanisms of proteasome assembly. Nat. Rev. Mol. Cell. Biol. 10, 104-115 (2009).
-
(2009)
Nat. Rev. Mol. Cell. Biol.
, vol.10
, pp. 104-115
-
-
Murata, S.1
Yashiroda, H.2
Tanaka, K.3
-
49
-
-
84857134729
-
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach
-
Lasker, K. et al. Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proc. Natl Acad. Sci. USA 109, 1380-1387 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 1380-1387
-
-
Lasker, K.1
-
50
-
-
0031820288
-
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
-
Longtine, M. S. et al. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14, 953-961 (1998).
-
(1998)
Yeast
, vol.14
, pp. 953-961
-
-
Longtine, M.S.1
-
51
-
-
0032873415
-
Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae
-
Goldstein, A. L. & McCusker, J. H. Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae. Yeast 15, 1541-1553 (1999).
-
(1999)
Yeast
, vol.15
, pp. 1541-1553
-
-
Goldstein, A.L.1
McCusker, J.H.2
-
52
-
-
27644576445
-
Characterization of the proteasome using native gel electrophoresis
-
Elsasser, S., Schmidt, M. & Finley, D. Characterization of the proteasome using native gel electrophoresis. Methods Enzymol. 398, 353-363 (2005).
-
(2005)
Methods Enzymol.
, vol.398
, pp. 353-363
-
-
Elsasser, S.1
Schmidt, M.2
Finley, D.3
-
53
-
-
0037108887
-
Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search
-
Keller, A., Nesvizhskii, A. I., Kolker, E. & Aebersold, R. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal. Chem. 74, 5383-5392 (2002).
-
(2002)
Anal. Chem.
, vol.74
, pp. 5383-5392
-
-
Keller, A.1
Nesvizhskii, A.I.2
Kolker, E.3
Aebersold, R.4
-
54
-
-
33745217791
-
SUNDIALS: Suite of nonlinear and differential/algebraic equation solvers
-
Hindmarsh, A. C. et al. SUNDIALS: Suite of nonlinear and differential/algebraic equation solvers. Acm Trans. Math Software 31, 363-396 (2005).
-
(2005)
Acm Trans. Math Software
, vol.31
, pp. 363-396
-
-
Hindmarsh, A.C.1
-
55
-
-
0142215475
-
Global analysis of protein expression in yeast
-
Ghaemmaghami, S. et al. Global analysis of protein expression in yeast. Nature 425, 737-741 (2003).
-
(2003)
Nature
, vol.425
, pp. 737-741
-
-
Ghaemmaghami, S.1
|