Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells

Tumor Biology

Volumn 36, Issue 2, 2015, Pages 1191-1198

  Hamzeloo Moghadam, Maryam ^a,e   Aghaei, Mahmoud ^b   Fallahian, Faranak ^c   Jafari, Seyyed Mehdi ^d,f   Dolati, Masoumeh ^c   Abdolmohammadi, Mohammad Hossein ^c   Hajiahmadi, Sima ^b   Esmaeili, Somayeh ^e  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c QOM UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^f ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Apoptosis; Breast cancer; Britannin; MCF 7; MDA MB 468; Sesquiterpene lactone

Indexed keywords

ANTINEOPLASTIC AGENT; BRITANNIN; CASPASE 3; CASPASE 9; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SESQUITERPENE LACTONE; UNCLASSIFIED DRUG; LACTONE; SESQUITERPENE;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; BIOSYNTHESIS; BREAST NEOPLASMS; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; MCF 7 CELL LINE; METABOLISM; PATHOLOGY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CASPASE 3; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LACTONES; MCF-7 CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES; SESQUITERPENES; SIGNAL TRANSDUCTION;

EID: 84925537428     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-2744-9     Document Type: Article

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