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Volumn 34, Issue 2, 2013, Pages 1085-1095

Adenosine induces cell cycle arrest and apoptosis via cyclinD1/Cdk4 and Bcl-2/Bax pathways in human ovarian cancer cell line OVCAR-3

Author keywords

Adenosine; Apoptosis; Cell cycle arrest; Ovarian cancer

Indexed keywords

ADENOSINE; ADENOSINE DEAMINASE INHIBITOR; BROXURIDINE; CASPASE 3; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; LIPOCORTIN 5; NUCLEOSIDE DERIVATIVE; NUCLEOSIDE TRANSPORTER; PROPIDIUM IODIDE; PROTEIN BAX; PROTEIN BCL 2; BAX PROTEIN, HUMAN; CCND1 PROTEIN, HUMAN; CDK4 PROTEIN, HUMAN; VASODILATOR AGENT;

EID: 84877123846     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-0650-1     Document Type: Article
Times cited : (95)

References (37)
  • 5
    • 0035938227 scopus 로고    scopus 로고
    • Biophasic cytotoxic mechanism of extracellulat ATP on U-937 human histiocytic leukemia cells: Involvement of adenosine generation
    • 11336790 10.1016/S0167-4889(01)00069-6 1:CAS:528:DC%2BD3MXivFehtr0%3D
    • Schneider C, Wiendl H, Ogilive A. Biophasic cytotoxic mechanism of extracellulat ATP on U-937 human histiocytic leukemia cells: involvement of adenosine generation. Biochim Biophys Acta. 2001;1538:190-205.
    • (2001) Biochim Biophys Acta , vol.1538 , pp. 190-205
    • Schneider, C.1    Wiendl, H.2    Ogilive, A.3
  • 7
    • 40449104597 scopus 로고    scopus 로고
    • Adenosine modulates cell growth in the human breast cancer cells via adenosine receptors
    • 18351132 10.3727/000000007783629981 1:CAS:528:DC%2BD1cXivFWru7g%3D
    • Panjehpour M, Karami-Tehrani F. Adenosine modulates cell growth in the human breast cancer cells via adenosine receptors. Oncol Res. 2007;16:575-85.
    • (2007) Oncol Res , vol.16 , pp. 575-585
    • Panjehpour, M.1    Karami-Tehrani, F.2
  • 8
    • 34247642621 scopus 로고    scopus 로고
    • Adenosine receptors in colon carcinoma tissues and colon tumoral cell lines: Focus on the A (3) adenosine subtype
    • 17348028 10.1002/jcp.20994 1:CAS:528:DC%2BD2sXkvFKlt7o%3D
    • Gessi S, Merighi S, Varani K, Cattabriga E, Benini A, Mirandola P, et al. Adenosine receptors in colon carcinoma tissues and colon tumoral cell lines: focus on the A (3) adenosine subtype. J Cell Physiol. 2007;211:826-36.
    • (2007) J Cell Physiol , vol.211 , pp. 826-836
    • Gessi, S.1    Merighi, S.2    Varani, K.3    Cattabriga, E.4    Benini, A.5    Mirandola, P.6
  • 9
    • 0028283266 scopus 로고
    • Apoptosis induced by adenosine in human leukemia HL-60 cells
    • 8020596 10.1006/excr.1994.1196 1:CAS:528:DyaK2cXksl2ntro%3D
    • Tanaka Y, Yoshihara K, Tsuyuki M, Kamiya T. Apoptosis induced by adenosine in human leukemia HL-60 cells. Exp Cell Res. 1994;213:242-52.
    • (1994) Exp Cell Res. , vol.213 , pp. 242-252
    • Tanaka, Y.1    Yoshihara, K.2    Tsuyuki, M.3    Kamiya, T.4
  • 10
    • 0036428630 scopus 로고    scopus 로고
    • Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells
    • 12406340 10.1046/j.1523-1747.2002.00111.x 1:CAS:528:DC%2BD38XovVarurs%3D
    • Merighi S, Mirandola P, Milani D, Varani K, Gessi S, Klotz KN, et al. Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells. J Invest Dermatol. 2002;119:923-33.
    • (2002) J Invest Dermatol. , vol.119 , pp. 923-933
    • Merighi, S.1    Mirandola, P.2    Milani, D.3    Varani, K.4    Gessi, S.5    Klotz, K.N.6
  • 11
    • 27144519159 scopus 로고    scopus 로고
    • Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway
    • 16202036 10.1111/j.1365-2184.2005.00349.x 1:CAS:528:DC%2BD2MXht1WktLjK
    • Hashemi M, Karami-Tehrani F, Ghavami S, Maddika S, Los M. Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway. Cell Prolif. 2005;38:269-85.
    • (2005) Cell Prolif. , vol.38 , pp. 269-285
    • Hashemi, M.1    Karami-Tehrani, F.2    Ghavami, S.3    Maddika, S.4    Los, M.5
  • 12
    • 0037841605 scopus 로고    scopus 로고
    • Biochemical studies of apoptosis induced by tamoxifen in estrogen receptor positive and negative breast cancer cell lines
    • 12810152 10.1016/S0009-9120(03)00007-9 1:CAS:528:DC%2BD3sXks1ejsbk%3D
    • Salami S, Karami-Tehrani F. Biochemical studies of apoptosis induced by tamoxifen in estrogen receptor positive and negative breast cancer cell lines. Clin Biochem. 2003;36(4):247-53.
    • (2003) Clin Biochem , vol.36 , Issue.4 , pp. 247-253
    • Salami, S.1    Karami-Tehrani, F.2
  • 13
    • 77952320422 scopus 로고    scopus 로고
    • Diagnostic value of adenosine deaminase activity in benign and malignant breast tumors
    • 10.1016/j.arcmed.2009.10.012
    • Aghaei M, Karami-Tehrani F, Salami S, Atri M. Diagnostic value of adenosine deaminase activity in benign and malignant breast tumors. Arch Med Res. 2009;41:14-8.
    • (2009) Arch Med Res. , vol.41 , pp. 14-18
    • Aghaei, M.1    Karami-Tehrani, F.2    Salami, S.3    Atri, M.4
  • 14
    • 33845650971 scopus 로고    scopus 로고
    • Analysis of cell cycle phases and progression in cultured mammalian cells
    • 17189856 10.1016/j.ymeth.2006.07.022 1:CAS:528:DC%2BD2sXhsFeltw%3D%3D
    • Schorl C, Sedivy JM. Analysis of cell cycle phases and progression in cultured mammalian cells. Methods. 2007;41:143-50.
    • (2007) Methods , vol.41 , pp. 143-150
    • Schorl, C.1    Sedivy, J.M.2
  • 15
    • 38349052450 scopus 로고    scopus 로고
    • S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP-kinase dependent pathway
    • 18339893 10.1189/jlb.0607397 1:CAS:528:DC%2BD1cXntVelsbY%3D
    • Ghavami S, Rashedi I, Dattilo BM, Eshraghi M, Chazin WJ, Hashemi M, et al. S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP-kinase dependent pathway. J Leukoc Biol. 2008;83:1484-92.
    • (2008) J Leukoc Biol , vol.83 , pp. 1484-1492
    • Ghavami, S.1    Rashedi, I.2    Dattilo, B.M.3    Eshraghi, M.4    Chazin, W.J.5    Hashemi, M.6
  • 16
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • 1710634 10.1016/0022-1759(91)90198-O 1:CAS:528:DyaK3MXltlenu7Y%3D
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods. 1991;139:271-9.
    • (1991) J Immunol Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 17
    • 77949270765 scopus 로고    scopus 로고
    • S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3
    • 19935772 10.1038/cr.2009.129 1:CAS:528:DC%2BC3cXisFejtbk%3D
    • Ghavami S, Eshragi M, Ande SR, Chazin WJ, Klonisch T, Halayko AJ, et al. S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3. Cell Res. 2010;20:314-31.
    • (2010) Cell Res. , vol.20 , pp. 314-331
    • Ghavami, S.1    Eshragi, M.2    Ande, S.R.3    Chazin, W.J.4    Klonisch, T.5    Halayko, A.J.6
  • 18
    • 80054727886 scopus 로고    scopus 로고
    • Molecular mechanism of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: Involvement of intrinsic pathway
    • 21830157 10.1007/s00432-011-1031-z 1:CAS:528:DC%2BC3MXhtFynt7zF
    • Aghaei M, Panjehpour M, Karami-tehrani F, Salami S. Molecular mechanism of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway. J Cancer Res Clin Oncol. 2011;137:1511-23.
    • (2011) J Cancer Res Clin Oncol , vol.137 , pp. 1511-1523
    • Aghaei, M.1    Panjehpour, M.2    Karami-Tehrani, F.3    Salami, S.4
  • 19
    • 3042740431 scopus 로고    scopus 로고
    • Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: The role of ROS and the effect of metal ions
    • 10.1189/jlb.0903435 1:CAS:528:DC%2BD2cXlsVOisL0%3D
    • Ghavami S, Kerkhoff C, Los M, Hashemi M, Sorg C, Karami-Tehrani F. Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: the role of ROS and the effect of metal ions. J Leuk Biol. 2004;76:169-75.
    • (2004) J Leuk Biol. , vol.76 , pp. 169-175
    • Ghavami, S.1    Kerkhoff, C.2    Los, M.3    Hashemi, M.4    Sorg, C.5    Karami-Tehrani, F.6
  • 20
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • 11734617 1:CAS:528:DC%2BD38XltVOltQ%3D%3D
    • Fredholm BB, IJzerman AP, Jacobson KA, Klotz KN, Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev. 2001;53:527-52.
    • (2001) Pharmacol Rev , vol.53 , pp. 527-552
    • Fredholm, B.B.1    Ijzerman, A.P.2    Jacobson, K.A.3    Klotz, K.N.4    Linden, J.5
  • 21
    • 0033921004 scopus 로고    scopus 로고
    • Adenosine acts as an inhibitor of lymphoma cell growth: A major role for the A3 adenosine receptor
    • 10.1016/S0959-8049(00)00130-1 1:CAS:528:DC%2BD3cXks12gtrk%3D
    • Fishman P, Yehuda SB, Ohana G, Pathak S, Wasserman L, Barer F, et al. Adenosine acts as an inhibitor of lymphoma cell growth: a major role for the A3 adenosine receptor. Euro J Cancer. 2000;36:1452-8.
    • (2000) Euro J Cancer. , vol.36 , pp. 1452-1458
    • Fishman, P.1    Yehuda, S.B.2    Ohana, G.3    Pathak, S.4    Wasserman, L.5    Barer, F.6
  • 22
    • 84856031113 scopus 로고    scopus 로고
    • Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and -independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3
    • 21656837 10.1002/pros.21438 1:CAS:528:DC%2BC38Xns12mtQ%3D%3D
    • Aghaei M, Karami-Tehrani F, Panjehpour M, Salami S, Fallahian F. Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and -independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3. Prostate. 2012;72:361-75.
    • (2012) Prostate , vol.72 , pp. 361-375
    • Aghaei, M.1    Karami-Tehrani, F.2    Panjehpour, M.3    Salami, S.4    Fallahian, F.5
  • 23
    • 42749096768 scopus 로고    scopus 로고
    • Inhibition of cell proliferation through cell cycle arrest and apoptosis by thio-Cl-IB-MECA, a novel A3 adenosine receptor agonist, in human lung cancer cells
    • 18321638 10.1016/j.canlet.2008.01.037 1:CAS:528:DC%2BD1cXlslSitrg%3D
    • Kim SJ, Min HY, Chung HJ, Park EJ, Hong JY, Kang YJ, et al. Inhibition of cell proliferation through cell cycle arrest and apoptosis by thio-Cl-IB-MECA, a novel A3 adenosine receptor agonist, in human lung cancer cells. Cancer Lett. 2008;264:309-15.
    • (2008) Cancer Lett , vol.264 , pp. 309-315
    • Kim, S.J.1    Min, H.Y.2    Chung, H.J.3    Park, E.J.4    Hong, J.Y.5    Kang, Y.J.6
  • 24
    • 0035195126 scopus 로고    scopus 로고
    • Differential effect of adenosine on tumor and normal cell growth: Focus on the A3 adenosine receptor
    • 11147810 10.1002/1097-4652(200101)186:1<19: AID-JCP1011>3.0.CO;2-3 1:CAS:528:DC%2BD3cXoslyqtro%3D
    • Ohana G, Bar-Yehuda S, Barer F, Fishman P. Differential effect of adenosine on tumor and normal cell growth: focus on the A3 adenosine receptor. J Cell Physiol. 2001;186:19-23.
    • (2001) J Cell Physiol , vol.186 , pp. 19-23
    • Ohana, G.1    Bar-Yehuda, S.2    Barer, F.3    Fishman, P.4
  • 25
    • 0001392890 scopus 로고    scopus 로고
    • Adenosine and hypoxia stimulate proliferation and migration of endothelial cells
    • Meininger CJ, Schelling ME, Granger HJ. Adenosine and hypoxia stimulate proliferation and migration of endothelial cells. Am J Physiol. 1998;255:554-62.
    • (1998) Am J Physiol , vol.255 , pp. 554-562
    • Meininger, C.J.1    Schelling, M.E.2    Granger, H.J.3
  • 26
    • 0034903452 scopus 로고    scopus 로고
    • Proliferation, migration, and ERK activation in human retinal endothelial cells through A(2B) adenosine receptor stimulation
    • 11481274 1:STN:280:DC%2BD3MvjtlKgtw%3D%3D
    • Grant MB, Davis MI, Caballero S, Feoktistov I, Biaggioni I, Belardinelli L. Proliferation, migration, and ERK activation in human retinal endothelial cells through A(2B) adenosine receptor stimulation. Invest Ophthalmol Vis Sci. 2001;42:2068-73.
    • (2001) Invest Ophthalmol Vis Sci. , vol.42 , pp. 2068-2073
    • Grant, M.B.1    Davis, M.I.2    Caballero, S.3    Feoktistov, I.4    Biaggioni, I.5    Belardinelli, L.6
  • 27
    • 0034743290 scopus 로고    scopus 로고
    • The A3 adenosine receptor induces cytoskeleton rearrangement in human astrocytoma cells via a specific action on Rho proteins
    • 11462805 10.1111/j.1749-6632.2001.tb03613.x 1:CAS:528: DC%2BD3MXlsV2ks78%3D
    • Abbracchio MP, Camurri A, Ceruti S, Cattabeni F, Falzano L, Giammarioli AM, et al. The A3 adenosine receptor induces cytoskeleton rearrangement in human astrocytoma cells via a specific action on Rho proteins. Ann N Y Acad Sci. 2001;939:63-73.
    • (2001) Ann N y Acad Sci , vol.939 , pp. 63-73
    • Abbracchio, M.P.1    Camurri, A.2    Ceruti, S.3    Cattabeni, F.4    Falzano, L.5    Giammarioli, A.M.6
  • 28
    • 0029871277 scopus 로고    scopus 로고
    • Induction of apoptosis in HL-60 human promyelocytic leukemia cells by adenosine A(3) receptor agonists
    • 8645277 10.1006/bbrc.1996.0331 1:CAS:528:DyaK28Xhs1antbY%3D
    • Kohno Y, Sei Y, Koshiba M, Kim HO, Jacobson KA. Induction of apoptosis in HL-60 human promyelocytic leukemia cells by adenosine A(3) receptor agonists. Biochem Biophys Res Commun. 1996;219:904-10.
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 904-910
    • Kohno, Y.1    Sei, Y.2    Koshiba, M.3    Kim, H.O.4    Jacobson, K.A.5
  • 29
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • 12209154 10.1038/nrc883 1:CAS:528:DC%2BD38Xmslamsrw%3D
    • Cory S, Adams JM. The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer. 2002;2:647-56.
    • (2002) Nat Rev Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 30
    • 0035706502 scopus 로고    scopus 로고
    • Roles of BCL-2 and caspase 3 in the adenosine A3 receptor-induced apoptosis
    • 11859924 10.1385/JMN:17:3:285 1:CAS:528:DC%2BD38Xht1Wjsb0%3D
    • Appel E, Kazimirsky G, Ashkenazi E, Kim SG, Jacobson KA, Brodien C. Roles of BCL-2 and caspase 3 in the adenosine A3 receptor-induced apoptosis. J Mol Neurosci. 2001;17:285-92.
    • (2001) J Mol Neurosci , vol.17 , pp. 285-292
    • Appel, E.1    Kazimirsky, G.2    Ashkenazi, E.3    Kim, S.G.4    Jacobson, K.A.5    Brodien, C.6
  • 31
    • 33645222035 scopus 로고    scopus 로고
    • Molecular mechanisms of adenosine-induced apoptosis in human HepG2 cells
    • 16539849 10.1111/j.1745-7254.2006.00302.x 1:CAS:528:DC%2BD28Xjs12jtrk%3D
    • Wu LF, Li GP, Feng JL, Pu ZJ. Molecular mechanisms of adenosine-induced apoptosis in human HepG2 cells. Acta Pharmacol Sin. 2006;27:477-84.
    • (2006) Acta Pharmacol Sin. , vol.27 , pp. 477-484
    • Wu, L.F.1    Li, G.P.2    Feng, J.L.3    Pu, Z.J.4
  • 32
    • 27744489875 scopus 로고    scopus 로고
    • Effect of protein kinase C alpha, caspase-3, and survivin on apoptosis of oral cancer cells induced by staurosporine
    • 16225760 10.1111/j.1745-7254.2005.00205.x 1:CAS:528:DC%2BD2MXht1alsb3N
    • Zhang YX, Yu SB, Ou-Yang JP, Xia D, Wang M, Li JR. Effect of protein kinase C alpha, caspase-3, and survivin on apoptosis of oral cancer cells induced by staurosporine. Acta Pharmacol Sin. 2005;26:1365-72.
    • (2005) Acta Pharmacol Sin. , vol.26 , pp. 1365-1372
    • Zhang, Y.X.1    Yu, S.B.2    Ou-Yang, J.P.3    Xia, D.4    Wang, M.5    Li, J.R.6
  • 33
    • 0034880557 scopus 로고    scopus 로고
    • Thymidine-dependent attenuation of the mitochondrial apoptotic pathway in adenosine induced apoptosis of HL-60 cell
    • 10.1007/s004320100264
    • Kang CM, Sun Y, Jang IS, Park SC. Thymidine-dependent attenuation of the mitochondrial apoptotic pathway in adenosine induced apoptosis of HL-60 cell. J Cancer Res Clin Oncol. 2001;12:570-6.
    • (2001) J Cancer Res Clin Oncol , vol.12 , pp. 570-576
    • Kang, C.M.1    Sun, Y.2    Jang, I.S.3    Park, S.C.4
  • 34
    • 22344440764 scopus 로고    scopus 로고
    • Adenosine triphosphate induces activation of caspase-3 in apoptosis of human granulosa-luteal cells
    • 16006727 10.1507/endocrj.52.327 1:CAS:528:DC%2BD2MXntVWrsrc%3D
    • Tai CJ, Chang SJ, Chien LY, Leung PC, Tzeng CR. Adenosine triphosphate induces activation of caspase-3 in apoptosis of human granulosa-luteal cells. Endocr J. 2005;52:327-35.
    • (2005) Endocr J , vol.52 , pp. 327-335
    • Tai, C.J.1    Chang, S.J.2    Chien, L.Y.3    Leung, P.C.4    Tzeng, C.R.5
  • 35
    • 77649183200 scopus 로고    scopus 로고
    • Adenosine suppresses CW2 human colonic cancer growth by inducing apoptosis via A1 adenosine receptors
    • 19822392 10.1016/j.canlet.2009.09.011 1:CAS:528:DC%2BC3cXivFGgu7o%3D
    • Saito M, Yaguchi T, Yasuda Y, Nakano T, Nishizaki T. Adenosine suppresses CW2 human colonic cancer growth by inducing apoptosis via A1 adenosine receptors. Cancer Lett. 2010;290:211-5.
    • (2010) Cancer Lett , vol.290 , pp. 211-215
    • Saito, M.1    Yaguchi, T.2    Yasuda, Y.3    Nakano, T.4    Nishizaki, T.5
  • 36
    • 1342324038 scopus 로고    scopus 로고
    • Emodininduced apoptosis through p53-dependent pathway in human hepatoma cells
    • 14987952 10.1016/j.lfs.2003.09.060 1:CAS:528:DC%2BD2cXhsVOkt7Y%3D
    • Shieh DE, Chen YY, Yen MH, Chiang LC, Lin CC. Emodininduced apoptosis through p53-dependent pathway in human hepatoma cells. Life Sci. 2004;74:2279-90.
    • (2004) Life Sci , vol.74 , pp. 2279-2290
    • Shieh, D.E.1    Chen, Y.Y.2    Yen, M.H.3    Chiang, L.C.4    Lin, C.C.5
  • 37
    • 0028167180 scopus 로고
    • P1 aspartate-based peptide alpha-((2,6-dichlorobenzoyl)oxy)methyl ketones as potent time-dependent inhibitors of interleukin-1 beta-converting enzyme
    • 8126694 10.1021/jm00031a003 1:CAS:528:DyaK2cXhsFaqu7s%3D
    • Dolle RE, Hoyer D, Prasad CV, Schmidt SJ, Helaszek CT, Miller RE, et al. P1 aspartate-based peptide alpha-((2,6-dichlorobenzoyl)oxy)methyl ketones as potent time-dependent inhibitors of interleukin-1 beta-converting enzyme. J Med Chem. 1994;37(5):563-4.
    • (1994) J Med Chem , vol.37 , Issue.5 , pp. 563-564
    • Dolle, R.E.1    Hoyer, D.2    Prasad, C.V.3    Schmidt, S.J.4    Helaszek, C.T.5    Miller, R.E.6


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