-
1
-
-
84880870139
-
Lessons from functional analysis of genome-wide association studies
-
COI: 1:CAS:528:DC%2BC3sXhtFSrtrvK, PID: 23832660
-
Sur I, Tuupanen S, Whitington T et al (2013) Lessons from functional analysis of genome-wide association studies. Cancer Res 73:4180–4184
-
(2013)
Cancer Res
, vol.73
, pp. 4180-4184
-
-
Sur, I.1
Tuupanen, S.2
Whitington, T.3
-
2
-
-
79951558318
-
National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological with 960 country-years and 9.1 million participants. Global burden of metabolic risk factors of chronic diseases collaborating group (Body Mass Index)
-
Finucane MM, Stevens GA, Cowan MJ et al (2011) National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological with 960 country-years and 9.1 million participants. Global burden of metabolic risk factors of chronic diseases collaborating group (Body Mass Index). Lancet 337:557–567
-
(2011)
Lancet
, vol.337
, pp. 557-567
-
-
Finucane, M.M.1
Stevens, G.A.2
Cowan, M.J.3
-
4
-
-
3543072186
-
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
-
COI: 1:CAS:528:DC%2BD2cXmtVOhsLk%3D, PID: 15286738
-
Calle EE, Kaaks R (2004) Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer 4:579–591
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 579-591
-
-
Calle, E.E.1
Kaaks, R.2
-
6
-
-
0037464510
-
Overweight, obesity, and mortality from cancer in a prospective studied cohort of U.S. adults
-
PID: 12711737
-
Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ (2003) Overweight, obesity, and mortality from cancer in a prospective studied cohort of U.S. adults. N Engl J Med 348:1625–1638
-
(2003)
N Engl J Med
, vol.348
, pp. 1625-1638
-
-
Calle, E.E.1
Rodriguez, C.2
Walker-Thurmond, K.3
Thun, M.J.4
-
7
-
-
84876423635
-
Metformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent manners
-
COI: 1:CAS:528:DC%2BC3sXntVWjs7s%3D, PID: 23620761
-
Sarfstein R, Friedman Y, Attias-Geva Z et al (2013) Metformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent manners. PLoS One 8:e61537
-
(2013)
PLoS One
, vol.8
, pp. 61537
-
-
Sarfstein, R.1
Friedman, Y.2
Attias-Geva, Z.3
-
8
-
-
0030667884
-
Dual effects of weight and weight gain on breast cancer risk
-
COI: 1:STN:280:DyaK1c%2Fhs1Sktw%3D%3D, PID: 9355998
-
Huang Z, Hankinson SE, Colditz GA et al (1997) Dual effects of weight and weight gain on breast cancer risk. JAMA 278:1407–1411
-
(1997)
JAMA
, vol.278
, pp. 1407-1411
-
-
Huang, Z.1
Hankinson, S.E.2
Colditz, G.A.3
-
9
-
-
0030913143
-
Body size and risk of breast cancer
-
COI: 1:STN:280:DyaK2szhtlegsw%3D%3D, PID: 9169910
-
Trentham-Dietz A, Newcomb PA, Storer BE et al (1997) Body size and risk of breast cancer. Am J Epidemiol 145:1011–1019
-
(1997)
Am J Epidemiol
, vol.145
, pp. 1011-1019
-
-
Trentham-Dietz, A.1
Newcomb, P.A.2
Storer, B.E.3
-
10
-
-
84860474009
-
Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy: extended follow-up of the Women’s Health Initiative randomised placebo-controlled trial
-
COI: 1:CAS:528:DC%2BC38Xmslyhsbw%3D, PID: 22401913
-
Anderson GL, Chlebowski RT, Aragaki AK et al (2012) Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy: extended follow-up of the Women’s Health Initiative randomised placebo-controlled trial. Lancet Oncol 13:476–486
-
(2012)
Lancet Oncol
, vol.13
, pp. 476-486
-
-
Anderson, G.L.1
Chlebowski, R.T.2
Aragaki, A.K.3
-
11
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
PID: 17658951
-
Scuteri A, Sanna S, Chen WM et al (2007) Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 3:e115
-
(2007)
PLoS Genet
, vol.3
, pp. 115
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.M.3
-
12
-
-
77958488285
-
The genetics of obesity
-
COI: 1:CAS:528:DC%2BC3cXhsVantr%2FK, PID: 20931363
-
Herrera BM, Lindgren CM (2010) The genetics of obesity. Curr Diab Rep 10:498–505
-
(2010)
Curr Diab Rep
, vol.10
, pp. 498-505
-
-
Herrera, B.M.1
Lindgren, C.M.2
-
13
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
COI: 1:CAS:528:DC%2BD2sXltVentL0%3D, PID: 17434869
-
Frayling TM, Timpson NJ, Weedon NM et al (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316:889–894
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, N.M.3
-
14
-
-
78049337953
-
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
-
COI: 1:CAS:528:DC%2BC3cXht1KmsL%2FN, PID: 20935630
-
Speliotes EK, Willer CJ, Berndt SI et al (2010) Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 42:937–948
-
(2010)
Nat Genet
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
-
16
-
-
67649875640
-
Loss-of-function mutation in the dioxygenaseencoding FTO gene causes severe growth retardation and multiple malformations
-
COI: 1:CAS:528:DC%2BD1MXhtVeltL7P, PID: 19559399
-
Boissel S, Reish O, Proulx K et al (2009) Loss-of-function mutation in the dioxygenaseencoding FTO gene causes severe growth retardation and multiple malformations. Am J Hum Genet 85:106–111
-
(2009)
Am J Hum Genet
, vol.85
, pp. 106-111
-
-
Boissel, S.1
Reish, O.2
Proulx, K.3
-
17
-
-
77449126999
-
Prevalence of loss of function FTO mutations in lean and obese individuals
-
COI: 1:CAS:528:DC%2BC3cXmtVKltg%3D%3D, PID: 19833892
-
Meyre D, Proulx K, Kawagoe-Takaki H et al (2010) Prevalence of loss of function FTO mutations in lean and obese individuals. Diabetes 59:311–318
-
(2010)
Diabetes
, vol.59
, pp. 311-318
-
-
Meyre, D.1
Proulx, K.2
Kawagoe-Takaki, H.3
-
18
-
-
47849093350
-
Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: current and developing technologies
-
COI: 1:CAS:528:DC%2BD1cXpsVamsr0%3D, PID: 18565787
-
Chorley BN, Wang X, Campbell MR et al (2008) Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: current and developing technologies. Mutat Res 659:147–157
-
(2008)
Mutat Res
, vol.659
, pp. 147-157
-
-
Chorley, B.N.1
Wang, X.2
Campbell, M.R.3
-
19
-
-
77950344277
-
Genetic variation at the FTO locus influences RBL2 gene expression
-
COI: 1:CAS:528:DC%2BC3cXjslegu7o%3D, PID: 20009087
-
Jowett JB, Curran JE, Johnson MP, Carless MA, Göring HH, Dyer TD et al (2010) Genetic variation at the FTO locus influences RBL2 gene expression. Diabetes 59(3):726–732
-
(2010)
Diabetes
, vol.59
, Issue.3
, pp. 726-732
-
-
Jowett, J.B.1
Curran, J.E.2
Johnson, M.P.3
Carless, M.A.4
Göring, H.H.5
Dyer, T.D.6
-
20
-
-
77954251048
-
Comment on: Jowett et al. (2010) Genetic variation at the FTO locus influences RBL2 gene expression. Diabetes; 59:726–732
-
COI: 1:CAS:528:DC%2BC3cXpsVOlsbo%3D, PID: 20393146
-
Berulava T, Horsthemke B (2010) Comment on: Jowett et al. (2010) Genetic variation at the FTO locus influences RBL2 gene expression. Diabetes; 59:726–732. Diabetes 59:e9
-
(2010)
Diabetes
, vol.59
, pp. 9
-
-
Berulava, T.1
Horsthemke, B.2
-
21
-
-
77955981202
-
The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels
-
COI: 1:CAS:528:DC%2BC3cXhtVCnurnK, PID: 20512162
-
Berulava T, Horsthemke B (2010) The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels. Eur J Hum Genet 18:1054–1056
-
(2010)
Eur J Hum Genet
, vol.18
, pp. 1054-1056
-
-
Berulava, T.1
Horsthemke, B.2
-
22
-
-
84897855294
-
Obesity-associated variants within FTO form long-range functional connections with IRX3
-
COI: 1:CAS:528:DC%2BC2cXks1Wlsbk%3D, PID: 24646999
-
Smemo S, Tena JJ, Kim KH, Gamazon ER, Sakabe NJ, Gómez-Marín C et al (2014) Obesity-associated variants within FTO form long-range functional connections with IRX3. Nature 507:371–375
-
(2014)
Nature
, vol.507
, pp. 371-375
-
-
Smemo, S.1
Tena, J.J.2
Kim, K.H.3
Gamazon, E.R.4
Sakabe, N.J.5
Gómez-Marín, C.6
-
23
-
-
68849083791
-
Obesity and cancer: Mendelian randomization approach utilizing the FTO genotype
-
PID: 19542184
-
Brennan P, McKay J, Moore L et al (2009) Obesity and cancer: Mendelian randomization approach utilizing the FTO genotype. Int J Epidemiol 38:971–975
-
(2009)
Int J Epidemiol
, vol.38
, pp. 971-975
-
-
Brennan, P.1
McKay, J.2
Moore, L.3
-
24
-
-
78149419139
-
Associations between an obesity related genetic variant (FTO rs9939609) and prostate cancer risk
-
PID: 20976066
-
Lewis SJ, Murad A, Chen L et al (2010) Associations between an obesity related genetic variant (FTO rs9939609) and prostate cancer risk. PLoS One 5:e13485
-
(2010)
PLoS One
, vol.5
, pp. 13485
-
-
Lewis, S.J.1
Murad, A.2
Chen, L.3
-
25
-
-
79955776932
-
FTO polymorphisms are associated with adult body mass index (BMI) and colorectal adenomas in African-Americans
-
COI: 1:CAS:528:DC%2BC3MXlvVygsr4%3D, PID: 21317302
-
Nock NL, Plummer SJ, Thompson CL et al (2011) FTO polymorphisms are associated with adult body mass index (BMI) and colorectal adenomas in African-Americans. Carcinogenesis 32:748–756
-
(2011)
Carcinogenesis
, vol.32
, pp. 748-756
-
-
Nock, N.L.1
Plummer, S.J.2
Thompson, C.L.3
-
26
-
-
84865686379
-
The risk of sporadic colorectal cancer development is not influenced by fat mass and obesity related gene polymorphism in Slavs
-
PID: 22857884
-
Hubacek JA, Dlouha D (2012) The risk of sporadic colorectal cancer development is not influenced by fat mass and obesity related gene polymorphism in Slavs. Eur J Intern Med 23:e175–e176
-
(2012)
Eur J Intern Med
, vol.23
, pp. 175-176
-
-
Hubacek, J.A.1
Dlouha, D.2
-
27
-
-
83555173280
-
The obesity gene and colorectal cancer risk: a population study in Northern Italy
-
COI: 1:STN:280:DC%2BC38%2FntVentA%3D%3D, PID: 22153534
-
Tarabra E, Actis GC, Fadda M et al (2012) The obesity gene and colorectal cancer risk: a population study in Northern Italy. Eur J Intern Med 23:65–69
-
(2012)
Eur J Intern Med
, vol.23
, pp. 65-69
-
-
Tarabra, E.1
Actis, G.C.2
Fadda, M.3
-
28
-
-
84864146334
-
Susceptibility variants for obesity and colorectal cancer risk: the multiethnic cohort and PAGE studies
-
COI: 1:CAS:528:DC%2BC38Xmt1Kjtbo%3D, PID: 22511254
-
Lim U, Wilkens LR, Monroe KR et al (2012) Susceptibility variants for obesity and colorectal cancer risk: the multiethnic cohort and PAGE studies. Int J Cancer 131:E1038–E1043
-
(2012)
Int J Cancer
, vol.131
, pp. 1038-1043
-
-
Lim, U.1
Wilkens, L.R.2
Monroe, K.R.3
-
29
-
-
79955752416
-
Body mass index and obesity- and diabetes-associated genotypes and risk for pancreatic cancer
-
COI: 1:CAS:528:DC%2BC3MXls1Kiu7k%3D, PID: 21357378
-
Tang H, Dong X, Hassan M et al (2011) Body mass index and obesity- and diabetes-associated genotypes and risk for pancreatic cancer. Cancer Epidemiol Biomarkers Prev 20:779–792
-
(2011)
Cancer Epidemiol Biomarkers Prev
, vol.20
, pp. 779-792
-
-
Tang, H.1
Dong, X.2
Hassan, M.3
-
30
-
-
79956263021
-
Association study of type 2 diabetes genetic susceptibility variants and risk of pancreatic cancer: an analysis of PanScan-I data
-
PID: 21445555
-
Pierce BL, Austin MA, Ahsan H (2011) Association study of type 2 diabetes genetic susceptibility variants and risk of pancreatic cancer: an analysis of PanScan-I data. Cancer Causes Control 22:877–883
-
(2011)
Cancer Causes Control
, vol.22
, pp. 877-883
-
-
Pierce, B.L.1
Austin, M.A.2
Ahsan, H.3
-
31
-
-
85027951288
-
Association between FTO gene polymorphism and cancer risk: evidence from 16,277 cases and 31,153 controls
-
COI: 1:CAS:528:DC%2BC38XhtVOhtb3M, PID: 22396042
-
Li G, Chen Q, Wang L, Ke D, Yuan Z (2012) Association between FTO gene polymorphism and cancer risk: evidence from 16,277 cases and 31,153 controls. Tumour Biol 33:1237–1243
-
(2012)
Tumour Biol
, vol.33
, pp. 1237-1243
-
-
Li, G.1
Chen, Q.2
Wang, L.3
Ke, D.4
Yuan, Z.5
-
32
-
-
84879832109
-
Association between variations in the fat mass and obesity-associated gene and pancreatic cancer risk: a case-control study in Japan
-
Lin Y, Ueda J, Yagyu K, Ishii H, Ueno M, Egawa N et al (2013) Association between variations in the fat mass and obesity-associated gene and pancreatic cancer risk: a case-control study in Japan. BMC Cancer 8(13):337
-
(2013)
BMC Cancer
, vol.8
, Issue.13
, pp. 337
-
-
Lin, Y.1
Ueda, J.2
Yagyu, K.3
Ishii, H.4
Ueno, M.5
Egawa, N.6
-
33
-
-
84871323211
-
Common obesity-related genetic variants and papillary thyroid cancer risk
-
COI: 1:CAS:528:DC%2BC38XhvVSqu7%2FO, PID: 23064004
-
Kitahara CM, Neta G, Pfeiffer RM et al (2012) Common obesity-related genetic variants and papillary thyroid cancer risk. Cancer Epidemiol Biomarkers Prev 21:2268–2271
-
(2012)
Cancer Epidemiol Biomarkers Prev
, vol.21
, pp. 2268-2271
-
-
Kitahara, C.M.1
Neta, G.2
Pfeiffer, R.M.3
-
34
-
-
80655149499
-
Association of obesity-related genetic variants with endometrial cancer risk: a report from the Shanghai endometrial cancer genetics study
-
PID: 21976109
-
Delahanty RJ, Beeghly-Fadiel A, Xiang YB et al (2011) Association of obesity-related genetic variants with endometrial cancer risk: a report from the Shanghai endometrial cancer genetics study. Am J Epidemiol 174:1115–1126
-
(2011)
Am J Epidemiol
, vol.174
, pp. 1115-1126
-
-
Delahanty, R.J.1
Beeghly-Fadiel, A.2
Xiang, Y.B.3
-
35
-
-
79951574847
-
The obesity-associated polymorphisms FTO rs9939609 and MC4R rs17782313 and endometrial cancer risk in non-Hispanic white women
-
COI: 1:CAS:528:DC%2BC3MXitlOqsLg%3D, PID: 21347432
-
Lurie G, Gaudet MM, Spurdle AB et al (2011) The obesity-associated polymorphisms FTO rs9939609 and MC4R rs17782313 and endometrial cancer risk in non-Hispanic white women. PLoS One 6:e16756
-
(2011)
PLoS One
, vol.6
, pp. 16756
-
-
Lurie, G.1
Gaudet, M.M.2
Spurdle, A.B.3
-
36
-
-
77955457093
-
No association between FTO or HHEX and endometrial cancer risk
-
COI: 1:CAS:528:DC%2BC3cXpvVejsbc%3D, PID: 20647405
-
Gaudet MM, Yang HP, Bosquet JG et al (2010) No association between FTO or HHEX and endometrial cancer risk. Cancer Epidemiol Biomarkers Prev 19:2106–2109
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 2106-2109
-
-
Gaudet, M.M.1
Yang, H.P.2
Bosquet, J.G.3
-
37
-
-
0026663163
-
Height and weight at various ages and risk of breast cancer
-
COI: 1:STN:280:DyaK2c7gtFWlug%3D%3D, PID: 1342311
-
Brinton L, Swanson C (1992) Height and weight at various ages and risk of breast cancer. Ann Epidemiol 2:597–609
-
(1992)
Ann Epidemiol
, vol.2
, pp. 597-609
-
-
Brinton, L.1
Swanson, C.2
-
38
-
-
84875983273
-
Evaluating genome-wide association study-identified breast cancer risk variants in African-American women
-
COI: 1:CAS:528:DC%2BC3sXmtlSmsrw%3D, PID: 23593120
-
Long J, Zhang B, Signorello LB et al (2013) Evaluating genome-wide association study-identified breast cancer risk variants in African-American women. PLoS One 8:e58350
-
(2013)
PLoS One
, vol.8
, pp. 58350
-
-
Long, J.1
Zhang, B.2
Signorello, L.B.3
-
39
-
-
79953842952
-
The role of the fat mass and obesity associated gene (FTO) in breast cancer risk
-
COI: 1:CAS:528:DC%2BC3MXltFKksr4%3D, PID: 21489227
-
Kaklamani V, Yi N, Sadim M et al (2011) The role of the fat mass and obesity associated gene (FTO) in breast cancer risk. BMC Med Genet 12:52
-
(2011)
BMC Med Genet
, vol.12
, pp. 52
-
-
Kaklamani, V.1
Yi, N.2
Sadim, M.3
-
40
-
-
84863812319
-
Influence of genomic variation in FTO at 16q12.2, MC4R at 18q22 and NRXN3 at 14q31 genes on breast cancer risk
-
COI: 1:CAS:528:DC%2BC38XhvVWlsrc%3D, PID: 21688152
-
Kusinska R, Górniak P, Pastorczak A et al (2012) Influence of genomic variation in FTO at 16q12.2, MC4R at 18q22 and NRXN3 at 14q31 genes on breast cancer risk. Mol Biol Rep 39:2915–2919
-
(2012)
Mol Biol Rep
, vol.39
, pp. 2915-2919
-
-
Kusinska, R.1
Górniak, P.2
Pastorczak, A.3
-
41
-
-
84871296763
-
Variation in genes related to obesity, weight, and weight change and risk of contralateral breast cancer in the WECARE Study population
-
COI: 1:CAS:528:DC%2BC38XhvVSqu7%2FN, PID: 23033454
-
Brooks JD, Bernstein L, Teraoka SN, Knight JA, Mellemkjær L, John EM et al (2012) Variation in genes related to obesity, weight, and weight change and risk of contralateral breast cancer in the WECARE Study population. Cancer Epidemiol Biomarkers Prev 21:2261–2267
-
(2012)
Cancer Epidemiol Biomarkers Prev
, vol.21
, pp. 2261-2267
-
-
Brooks, J.D.1
Bernstein, L.2
Teraoka, S.N.3
Knight, J.A.4
Mellemkjær, L.5
John, E.M.6
-
42
-
-
84875701351
-
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet 45:392–8
-
Garcia-Closas M, Couch FJ, Lindstrom S et al (2013) Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet 45:392–8, 398e1-2
-
(2013)
398e1-2
-
-
Garcia-Closas, M.1
Couch, F.J.2
Lindstrom, S.3
-
43
-
-
84890379867
-
Interaction between obesity-related genes, FTO and MC4R, associated to an increase of breast cancer risk
-
PID: 24091943
-
da Cunha PA, de Carlos Back LK, Sereia AF et al (2013) Interaction between obesity-related genes, FTO and MC4R, associated to an increase of breast cancer risk. Mol Biol Rep 40:6657–6664
-
(2013)
Mol Biol Rep
, vol.40
, pp. 6657-6664
-
-
da Cunha, P.A.1
de Carlos Back, L.K.2
Sereia, A.F.3
-
44
-
-
84875722359
-
A variant in FTO shows association with melanoma risk not due to BMI
-
COI: 1:CAS:528:DC%2BC3sXjtlOisLk%3D, PID: 23455637
-
Iles MM, Law MH, Stacey SN et al (2013) A variant in FTO shows association with melanoma risk not due to BMI. Nat Genet 45:428–432
-
(2013)
Nat Genet
, vol.45
, pp. 428-432
-
-
Iles, M.M.1
Law, M.H.2
Stacey, S.N.3
|