Variation in genes related to obesity, weight, and weight change and risk of contralateral breast cancer in the WECARE Study population

Cancer Epidemiology Biomarkers and Prevention

Volumn 21, Issue 12, 2012, Pages 2261-2267

  Brooks, Jennifer D ^a   Bernstein, Leslie ^b   Teraoka, Sharon N ^e   Knight, Julia A ^f   Mellemkjær, Lene ^g   John, Esther M ^c   Malone, Kathleen E ^h   Reiner, Anne S ^a   Lynch, Charles F ⁱ   Concannon, Patrick ^e   Haile, Robert W ^d   Bernstein, Jonine L ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^c CANCER PREVENTION INSTITUTE OF CALIFORNIA   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e UNIVERSITY OF VIRGINIA   (United States)

^f MOUNT SINAI HOSPITAL   (Canada)

^g DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^h USA   (United States)

ⁱ UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE TISSUE; ARTICLE; BODY MASS; BODY WEIGHT; BREAST CANCER; CANCER RISK; CAUCASIAN; CONTRALATERAL BREAST CANCER; CONTROLLED STUDY; ENERGY BALANCE; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; INFLAMMATION; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; WEIGHT CHANGE;

BODY MASS INDEX; BODY WEIGHT; BREAST NEOPLASMS; CASE-CONTROL STUDIES; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; NEOPLASMS, SECOND PRIMARY; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; UNITED STATES;

EID: 84871296763     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-12-1036     Document Type: Article

References (10)

1. Li CI, Daling JR, Porter PL, Tang M-TC, Malone KE. Relationship between potentially modifiable lifestyle factors and risk of second primary contralateral breast cancer among women diagnosed with estrogen receptor-positive invasive breast cancer. J Clin Oncol 2009;27:5312-8.
2. Brooks J, John E, Mellemkjær L, Reiner A, Malone K, Lynch C, et al. Body mass index and risk of second primary breast cancer: the WECARE Study. Breast Cancer Res Treat 2012;131:571-80.
3. Neilson HK, Friedenreich CM, Brockton NT, Millikan RC. Physical activity and postmenopausal breast cancer: proposed biologic mechanisms and areas for future research. Cancer Epidemiol Biomarkers Prev 2009;18:11-27.
4. Brooks JD, Teraoka SN, Reiner AS, Satagopan JM, Bernstein L, Thomas DC, et al. Variants in activators and downstream targets of ATM, radiation exposure, and contralateral breast cancer risk in the WECARE Study. Hum Mutat 2012;33:158-64.
5. Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009;41:25-34.
6. Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, Hu T, et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008;40:638-45. (Pubitemid 351601209)
7. Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, Helgadottir A, et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009;41:18-24.
8. Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER III, Hurov KE, Luo J, et al. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 2007;316:1160-6. (Pubitemid 46877472)
9. Bernstein J, Langholz B, Haile R, Bernstein L, Thomas D, Stovall M, et al. Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE Study. Breast Cancer Res 2004;6:R199-214.
10. Conneely KN, Boehnke M. So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests. Am J Hum Genet 2007;81:1158-68. (Pubitemid 350211447)