메뉴 건너뛰기




Volumn 67, Issue 12, 2007, Pages 5737-5746

Transforming growth factor-β signaling in prostate stromal cells supports prostate carcinoma growth by up-regulating stromal genes related to tissue remodeling

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

EID: 34250863385     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-0444     Document Type: Article
Times cited : (75)

References (48)
  • 1
    • 10344234761 scopus 로고    scopus 로고
    • Molecular insights into prostate cancer progression: The missing link of tumor microenvironment
    • Chung LW, Baseman A, Assikis V, Zhau HE. Molecular insights into prostate cancer progression: the missing link of tumor microenvironment. J Urol 2005;173:10-20.
    • (2005) J Urol , vol.173 , pp. 10-20
    • Chung, L.W.1    Baseman, A.2    Assikis, V.3    Zhau, H.E.4
  • 2
    • 0035500487 scopus 로고    scopus 로고
    • Cellular senescence as a tumor-suppressor mechanism
    • Campisi J. Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol 2001;11:S27-31.
    • (2001) Trends Cell Biol , vol.11
    • Campisi, J.1
  • 3
    • 0036829090 scopus 로고    scopus 로고
    • Cancer and aging: A model for the cancer promoting effects of the aging stroma
    • Krtolica A, Campisi J. Cancer and aging: a model for the cancer promoting effects of the aging stroma. Int J Biochem Cell Biol 2002;34:1401-14.
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1401-1414
    • Krtolica, A.1    Campisi, J.2
  • 4
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak HF. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 1986;315:1650-9.
    • (1986) N Engl J Med , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 5
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004;432:332-7.
    • (2004) Nature , vol.432 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 8
    • 3242802874 scopus 로고    scopus 로고
    • TGF-β-induced SMAD signaling and gene regulation: Consequences for extracellular matrix remodeling and wound healing
    • Schiller M, Javelaud D, Mauviel A. TGF-β-induced SMAD signaling and gene regulation: consequences for extracellular matrix remodeling and wound healing. J Dermatol Sci 2004;35:83-92.
    • (2004) J Dermatol Sci , vol.35 , pp. 83-92
    • Schiller, M.1    Javelaud, D.2    Mauviel, A.3
  • 9
    • 0031685620 scopus 로고    scopus 로고
    • Massague J. TGF-h signal transduction. Annu Rev Biochem 1998;67:753-91.
    • Massague J. TGF-h signal transduction. Annu Rev Biochem 1998;67:753-91.
  • 10
    • 0036965929 scopus 로고    scopus 로고
    • TGF-h and the Smad signal transduction pathway
    • Mehra A, Wrana JL. TGF-h and the Smad signal transduction pathway. Biochem Cell Biol 2002;80:605-22.
    • (2002) Biochem Cell Biol , vol.80 , pp. 605-622
    • Mehra, A.1    Wrana, J.L.2
  • 11
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor β in human disease
    • Blobe GC, Schiemann WP, Lodish HF. Role of transforming growth factor β in human disease. N Engl J Med 2000;342:1350-8.
    • (2000) N Engl J Med , vol.342 , pp. 1350-1358
    • Blobe, G.C.1    Schiemann, W.P.2    Lodish, H.F.3
  • 12
    • 2442696844 scopus 로고    scopus 로고
    • Tumor-suppressive and promoting function of transforming growth factor β
    • Sun L. Tumor-suppressive and promoting function of transforming growth factor β. Front Biosci 2004;9:1925-35.
    • (2004) Front Biosci , vol.9 , pp. 1925-1935
    • Sun, L.1
  • 13
    • 0031776562 scopus 로고    scopus 로고
    • Loss of expression of transforming growth factor-β receptors is associated with poor prognosis in prostate cancer patients
    • Kim IY, Ahn HJ, Lang S, et al. Loss of expression of transforming growth factor-β receptors is associated with poor prognosis in prostate cancer patients. Clin Cancer Res 1998;4:1625-30.
    • (1998) Clin Cancer Res , vol.4 , pp. 1625-1630
    • Kim, I.Y.1    Ahn, H.J.2    Lang, S.3
  • 14
    • 0031974364 scopus 로고    scopus 로고
    • A kinase-defective transforming growth factor-β receptor type II is a dominant-negative regulator for human breast carcinoma MCF-7 cells
    • Ko Y, Koli KM, Banerji SS, et al. A kinase-defective transforming growth factor-β receptor type II is a dominant-negative regulator for human breast carcinoma MCF-7 cells. Int J Oncol 1998;12:87-94.
    • (1998) Int J Oncol , vol.12 , pp. 87-94
    • Ko, Y.1    Koli, K.M.2    Banerji, S.S.3
  • 15
    • 0028075837 scopus 로고
    • Expression of transforming growth factor β type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells
    • Sun L, Wu G, Willson JK, et al. Expression of transforming growth factor β type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells. J Biol Chem 1994;269:26449-55.
    • (1994) J Biol Chem , vol.269 , pp. 26449-26455
    • Sun, L.1    Wu, G.2    Willson, J.K.3
  • 16
    • 0029131403 scopus 로고
    • Demonstration that mutation of the type II transforming growth factor β receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
    • Wang J, Sun L, Myeroff L, et al. Demonstration that mutation of the type II transforming growth factor β receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. J Biol Chem 1995;270:22044-9.
    • (1995) J Biol Chem , vol.270 , pp. 22044-22049
    • Wang, J.1    Sun, L.2    Myeroff, L.3
  • 17
    • 0242285692 scopus 로고    scopus 로고
    • TGF-β switches from tumor suppressor to prometastatic factor in a model of breast cancer progression
    • Tang B, Vu M, Booker T, et al. TGF-β switches from tumor suppressor to prometastatic factor in a model of breast cancer progression. J Clin Invest 2003;112:1116-24.
    • (2003) J Clin Invest , vol.112 , pp. 1116-1124
    • Tang, B.1    Vu, M.2    Booker, T.3
  • 18
    • 33745146191 scopus 로고    scopus 로고
    • Large- and small-molecule inhibitors of transforming growth factor-β signaling
    • Akhurst RJ. Large- and small-molecule inhibitors of transforming growth factor-β signaling. Curr Opin Investig Drugs 2006;7:513-21.
    • (2006) Curr Opin Investig Drugs , vol.7 , pp. 513-521
    • Akhurst, R.J.1
  • 19
    • 0842288323 scopus 로고    scopus 로고
    • TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
    • Bhowmick NA, Chytil A, Plieth D, et al. TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 2004;303:848-51.
    • (2004) Science , vol.303 , pp. 848-851
    • Bhowmick, N.A.1    Chytil, A.2    Plieth, D.3
  • 20
    • 23744452875 scopus 로고    scopus 로고
    • Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through up-regulation of TGF-α-, MSP- and HGF-mediated signaling networks
    • Cheng N, Bhowmick NA, Chytil A, et al. Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through up-regulation of TGF-α-, MSP- and HGF-mediated signaling networks. Oncogene 2005;24:5053-68.
    • (2005) Oncogene , vol.24 , pp. 5053-5068
    • Cheng, N.1    Bhowmick, N.A.2    Chytil, A.3
  • 21
    • 14944363173 scopus 로고    scopus 로고
    • Systemic administration of a soluble betaglycan suppresses tumor growth, angiogenesis, and matrix metalloproteinase-9 expression in a human xenograft model of prostate cancer
    • Bandyopadhyay A, Wang L, Lopez-Casillas F, Mendoza V, Yeh IT, Sun L. Systemic administration of a soluble betaglycan suppresses tumor growth, angiogenesis, and matrix metalloproteinase-9 expression in a human xenograft model of prostate cancer. Prostate 2005;63:81-90.
    • (2005) Prostate , vol.63 , pp. 81-90
    • Bandyopadhyay, A.1    Wang, L.2    Lopez-Casillas, F.3    Mendoza, V.4    Yeh, I.T.5    Sun, L.6
  • 22
    • 33746145265 scopus 로고    scopus 로고
    • Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-β type I receptor kinase inhibitor
    • Bandyopadhyay A, Agyin JK, Wang L, et al. Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-β type I receptor kinase inhibitor. Cancer Res 2006;66:6714-21.
    • (2006) Cancer Res , vol.66 , pp. 6714-6721
    • Bandyopadhyay, A.1    Agyin, J.K.2    Wang, L.3
  • 23
    • 0029047362 scopus 로고
    • A biomarker that identifies senescent human cells in culture and in aging skin in vivo
    • Dimri GP, Lee X, Basile G, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A 1995;92:9363-7.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.2    Basile, G.3
  • 25
    • 25144454435 scopus 로고    scopus 로고
    • Development and gene expression profiling of a metastatic variant of the human breast cancer MDAMB-435 cells
    • Bandyopadhyay A, Elkahloun A, Baysa SJ, Wang L, Sun LZ. Development and gene expression profiling of a metastatic variant of the human breast cancer MDAMB-435 cells. Cancer Biol Ther 2005;4:168-74.
    • (2005) Cancer Biol Ther , vol.4 , pp. 168-174
    • Bandyopadhyay, A.1    Elkahloun, A.2    Baysa, S.J.3    Wang, L.4    Sun, L.Z.5
  • 26
    • 33749549246 scopus 로고    scopus 로고
    • Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence
    • Coppe JP, Kauser K, Campisi J, Beausejour CM. Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence. J Biol Chem 2006;281:29568-74.
    • (2006) J Biol Chem , vol.281 , pp. 29568-29574
    • Coppe, J.P.1    Kauser, K.2    Campisi, J.3    Beausejour, C.M.4
  • 27
    • 0035834121 scopus 로고    scopus 로고
    • Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
    • Krtolica A, Parrinello S, Lockett S, Desprez PY, Campisi J. Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc Natl Acad Sci U S A 2001;98:12072-7.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12072-12077
    • Krtolica, A.1    Parrinello, S.2    Lockett, S.3    Desprez, P.Y.4    Campisi, J.5
  • 28
    • 5444261094 scopus 로고    scopus 로고
    • The stroma reaction myofibroblast: A key player in the control of tumor cell behavior
    • Desmouliere A, Guyot C, Gabbiani G. The stroma reaction myofibroblast: a key player in the control of tumor cell behavior. Int J Dev Biol 2004;48:509-17.
    • (2004) Int J Dev Biol , vol.48 , pp. 509-517
    • Desmouliere, A.1    Guyot, C.2    Gabbiani, G.3
  • 29
    • 0036718369 scopus 로고    scopus 로고
    • Reactive stroma in human prostate cancer: Induction of myofibroblast phenotype and extracellular matrix remodeling
    • Tuxhorn JA, Ayala GE, Smith MJ, Smith VC, Dang TD, Rowley DR. Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling. Clin Cancer Res 2002;8:2912-23.
    • (2002) Clin Cancer Res , vol.8 , pp. 2912-2923
    • Tuxhorn, J.A.1    Ayala, G.E.2    Smith, M.J.3    Smith, V.C.4    Dang, T.D.5    Rowley, D.R.6
  • 31
    • 2642524382 scopus 로고    scopus 로고
    • Transforming growth factor-β 1 specifically induce proteins involved in the myofibroblast contractile apparatus
    • Malmstrom J, Lindberg H, Lindberg C, et al. Transforming growth factor-β 1 specifically induce proteins involved in the myofibroblast contractile apparatus. Mol Cell Proteomics 2004;3:466-77.
    • (2004) Mol Cell Proteomics , vol.3 , pp. 466-477
    • Malmstrom, J.1    Lindberg, H.2    Lindberg, C.3
  • 32
    • 33747622327 scopus 로고    scopus 로고
    • Myosin-X is a molecular motor that functions in filopodia formation
    • Bohil AB, Robertson BW, Cheney RE. Myosin-X is a molecular motor that functions in filopodia formation. Proc Natl Acad Sci U S A 2006;103:12411-6.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 12411-12416
    • Bohil, A.B.1    Robertson, B.W.2    Cheney, R.E.3
  • 33
    • 4344672090 scopus 로고    scopus 로고
    • Myofibroblast development is characterized by specific cell-cell adherens junctions
    • Hinz B, Pittet P, Smith-Clerc J, Chaponnier C, Meister JJ. Myofibroblast development is characterized by specific cell-cell adherens junctions. Mol Biol Cell 2004;15:4310-20.
    • (2004) Mol Biol Cell , vol.15 , pp. 4310-4320
    • Hinz, B.1    Pittet, P.2    Smith-Clerc, J.3    Chaponnier, C.4    Meister, J.J.5
  • 34
    • 7244250188 scopus 로고    scopus 로고
    • Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-β or wounding
    • De Wever O, Westbroek W, Verloes A, et al. Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-β or wounding. J Cell Sci 2004;117:4691-703.
    • (2004) J Cell Sci , vol.117 , pp. 4691-4703
    • De Wever, O.1    Westbroek, W.2    Verloes, A.3
  • 35
    • 21244469490 scopus 로고    scopus 로고
    • Tenascin-C regulates recruitment of myofibroblasts during tissue repair after myocardial injury
    • Tamaoki M, Imanaka-Yoshida K, Yokoyama K, et al. Tenascin-C regulates recruitment of myofibroblasts during tissue repair after myocardial injury. Am J Pathol 2005;167:71-80.
    • (2005) Am J Pathol , vol.167 , pp. 71-80
    • Tamaoki, M.1    Imanaka-Yoshida, K.2    Yokoyama, K.3
  • 36
    • 0034131169 scopus 로고    scopus 로고
    • Tetraspanins are localized at motility-related structures and involved in normal human keratinocyte wound healing migration
    • Penas PF, Garcia-Diez A, Sanchez-Madrid F, Yanez-Mo M. Tetraspanins are localized at motility-related structures and involved in normal human keratinocyte wound healing migration. J Invest Dermatol 2000;114:1126-35.
    • (2000) J Invest Dermatol , vol.114 , pp. 1126-1135
    • Penas, P.F.1    Garcia-Diez, A.2    Sanchez-Madrid, F.3    Yanez-Mo, M.4
  • 37
    • 0037930878 scopus 로고    scopus 로고
    • The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells
    • Abram CL, Seals DF, Pass I, et al. The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells. J Biol Chem 2003;278:16844-51.
    • (2003) J Biol Chem , vol.278 , pp. 16844-16851
    • Abram, C.L.1    Seals, D.F.2    Pass, I.3
  • 38
    • 13844264301 scopus 로고    scopus 로고
    • The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells
    • Seals DF, Azucena EF, Jr., Pass I, et al. The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells. Cancer Cell 2005;7:155-65.
    • (2005) Cancer Cell , vol.7 , pp. 155-165
    • Seals, D.F.1    Azucena Jr., E.F.2    Pass, I.3
  • 39
    • 33646581758 scopus 로고    scopus 로고
    • The role of human HtrA1 in arthritic disease
    • Grau S, Richards PJ, Kerr B, et al. The role of human HtrA1 in arthritic disease. J Biol Chem 2006;281:6124-9.
    • (2006) J Biol Chem , vol.281 , pp. 6124-6129
    • Grau, S.1    Richards, P.J.2    Kerr, B.3
  • 40
    • 12144289397 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-I and tumour growth, invasion, and metastasis
    • Durand MK, Bodker JS, Christensen A, et al. Plasminogen activator inhibitor-I and tumour growth, invasion, and metastasis. Thromb Haemost 2004;91:438-49.
    • (2004) Thromb Haemost , vol.91 , pp. 438-449
    • Durand, M.K.1    Bodker, J.S.2    Christensen, A.3
  • 41
    • 0042440692 scopus 로고    scopus 로고
    • SERPINE2 (protease nexin I) promotes extracellular matrix production and local invasion of pancreatic tumors in vivo
    • Buchholz M, Biebl A, Neesse A, et al. SERPINE2 (protease nexin I) promotes extracellular matrix production and local invasion of pancreatic tumors in vivo. Cancer Res 2003;63:4945-51.
    • (2003) Cancer Res , vol.63 , pp. 4945-4951
    • Buchholz, M.1    Biebl, A.2    Neesse, A.3
  • 42
    • 33747589649 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-3 is up-regulated by transforming growth factor-β1 in vitro and expressed in fibroblastic foci in vivo in idiopathic pulmonary fibrosis
    • Garcia-Alvarez J, Ramirez R, Checa M, et al. Tissue inhibitor of metalloproteinase-3 is up-regulated by transforming growth factor-β1 in vitro and expressed in fibroblastic foci in vivo in idiopathic pulmonary fibrosis. Exp Lung Res 2006;32:201-14.
    • (2006) Exp Lung Res , vol.32 , pp. 201-214
    • Garcia-Alvarez, J.1    Ramirez, R.2    Checa, M.3
  • 43
    • 33749320619 scopus 로고    scopus 로고
    • Increased levels of transforming growth factor β receptor type I and up-regulation of matrix gene program: A model of scleroderma
    • Pannu J, Gardner H, Shearstone JR, Smith E, Trojanowska M. Increased levels of transforming growth factor β receptor type I and up-regulation of matrix gene program: a model of scleroderma. Arthritis Rheum 2006;54:3011-21.
    • (2006) Arthritis Rheum , vol.54 , pp. 3011-3021
    • Pannu, J.1    Gardner, H.2    Shearstone, J.R.3    Smith, E.4    Trojanowska, M.5
  • 44
    • 13144281709 scopus 로고    scopus 로고
    • Duel nature of TGF-β signaling: Tumor suppressor vs. tumor promoter
    • Bachman KE, Park BH. Duel nature of TGF-β signaling: tumor suppressor vs. tumor promoter. Curr Opin Oncol 2005;17:49-54.
    • (2005) Curr Opin Oncol , vol.17 , pp. 49-54
    • Bachman, K.E.1    Park, B.H.2
  • 45
    • 0036828120 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-β activity decreases angiogenesis in a human prostate cancer-reactive stroma xenograft model
    • Tuxhorn JA, McAlhany SJ, Yang F, Dang TD, Rowley DR. Inhibition of transforming growth factor-β activity decreases angiogenesis in a human prostate cancer-reactive stroma xenograft model. Cancer Res 2002;62:6021-5.
    • (2002) Cancer Res , vol.62 , pp. 6021-6025
    • Tuxhorn, J.A.1    McAlhany, S.J.2    Yang, F.3    Dang, T.D.4    Rowley, D.R.5
  • 46
    • 0031009081 scopus 로고    scopus 로고
    • General principles of wound healing
    • Witte MB, Barbul A. General principles of wound healing. Surg Clin North Am 1997;77:509-28.
    • (1997) Surg Clin North Am , vol.77 , pp. 509-528
    • Witte, M.B.1    Barbul, A.2
  • 47
    • 3142662147 scopus 로고    scopus 로고
    • Recombinant hepatocyte growth factor accelerates cutaneous wound healing in a diabetic mouse model
    • Yoshida S, Matsumoto K, Tomioka D, et al. Recombinant hepatocyte growth factor accelerates cutaneous wound healing in a diabetic mouse model. Growth Factors 2004;22:111-9.
    • (2004) Growth Factors , vol.22 , pp. 111-119
    • Yoshida, S.1    Matsumoto, K.2    Tomioka, D.3
  • 48
    • 0037312985 scopus 로고    scopus 로고
    • Neutralization of hepatocyte growth factor leads to retarded cutaneous wound healing associated with decreased neovascularization and granulation tissue formation
    • Yoshida S, Yamaguchi Y, Itami S, et al. Neutralization of hepatocyte growth factor leads to retarded cutaneous wound healing associated with decreased neovascularization and granulation tissue formation. J Invest Dermatol 2003;120:335-43.
    • (2003) J Invest Dermatol , vol.120 , pp. 335-343
    • Yoshida, S.1    Yamaguchi, Y.2    Itami, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.