Surface-bound TGF-β1 on effusion-derived exosomes participates in maintenance of number and suppressive function of regulatory T-cells in malignant effusions

Anticancer Research

Volumn 30, Issue 9, 2010, Pages 3747-3757

  Wada, Junji ^a   Onishi, Hideya ^a   Suzuki, Hiroyuki ^a   Yamasaki, Akio ^a   Nagai, Shuntaro ^a   Morisaki, Takashi ^b   Katano, Mitsuo ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b Fukuoka General Cancer Clinic   (Japan)

Author keywords

Exosome; Malignant effusion; Regulatory T cells; TGF 1

Indexed keywords

TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CD4+ T LYMPHOCYTE; CELL COUNT; CELL FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; EXOSOME; FLOW CYTOMETRY; HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PLEURA EFFUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; TUMOR CELL; CELL SEPARATION; COCULTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; IMMUNOLOGY; MALIGNANT PLEURA EFFUSION; METABOLISM; MONONUCLEAR CELL; NEOPLASM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CELL SEPARATION; COCULTURE TECHNIQUES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXOSOMES; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; LEUKOCYTES, MONONUCLEAR; NEOPLASMS; PLEURAL EFFUSION, MALIGNANT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77958553947     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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