The inhibitory effects of Geranium thunbergii on interferon-γ- and LPS-induced infammatory responses are mediated by Nrf2 activation

International Journal of Molecular Medicine

Volumn 35, Issue 5, 2015, Pages 1237-1245

  Choi, Hee Jin ^a,b   Choi, Hee Jung ^b   Park, Mi Ju ^b   Lee, Ji Yeon ^b   Jeong, Seung Il ^c   Lee, Seongoo ^d   Kim, Kyun Ha ^b   Joo, Myungsoo ^b   Jeong, Han Sol ^b   Kim, Jai Eun ^a   Ha, Ki Tae ^b  

^a Dongguk University   (South Korea)

^b Pusan National University   (South Korea)

^c Jeonju Biomaterials Institute   (South Korea)

^d Sangji University   (South Korea)

Author keywords

Geranium thunbergii; Inflammation; Interferon ; Lipopolysaccharide; Nuclear factor erythroid 2 related factor 2

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; GAMMA INTERFERON; GERANIIN; GERANIUM THUNBERGII EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; PLANT EXTRACT; QUERCETIN; RNA; SULFORAPHANE; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CELL VIABILITY ASSAY; CONTROLLED STUDY; DRUG CYTOTOXICITY; ESCHERICHIA COLI; GERANIUM; GERANIUM THUNBERGII; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFLAMMATION; INFLAMMATORY DISEASE; INNATE IMMUNITY; KOREA; KOREAN MEDICINE; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRADITIONAL MEDICINE; WESTERN BLOTTING; ANIMAL; CELL LINE; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; IMMUNOLOGY; ISOLATION AND PURIFICATION; MACROPHAGE; METABOLISM;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GERANIUM; INFLAMMATION; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; NF-E2-RELATED FACTOR 2; NF-KAPPA B; PLANT EXTRACTS;

EID: 84925445957     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2128     Document Type: Article

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