Design of LVFFARK and LVFFARK-Functionalized Nanoparticles for Inhibiting Amyloid β-Protein Fibrillation and Cytotoxicity

ACS Applied Materials and Interfaces

Volumn 7, Issue 10, 2015, Pages 5650-5662

  Xiong, Neng ^a   Dong, Xiao Yan ^a   Zheng, Jie ^b   Liu, Fu Feng ^a   Sun, Yan ^a  

^a TIANJIN UNIVERSITY   (China)

^b University of Akron   (United States)

Author keywords

Alzheimer's disease; amyloid protein; nanoparticle; peptide inhibitor; protein aggregation; self assembly

Indexed keywords

CYTOTOXICITY; GLYCOPROTEINS; NANOPARTICLES; NEURODEGENERATIVE DISEASES; PEPTIDES;

ALZHEIMER'S DISEASE; DESIGN AND DEVELOPMENT; FUNCTIONALIZED NANOPARTICLES; HYDROPHOBIC FRAGMENTS; PEPTIDE INHIBITORS; POLY(LACTIC-CO-GLYCOLIC ACID); PROTEIN AGGREGATION; SELF ASSEMBLY CHARACTERISTICS;

SELF ASSEMBLY;

AMYLOID; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); LACTIC ACID; NANOCAPSULE; NANOCONJUGATE; PEPTIDE; PEPTIDE FRAGMENT; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DIFFUSION; DRUG DESIGN; DRUG EFFECTS; NERVE CELL; PARTICLE SIZE; PC12 CELL LINE; PHYSIOLOGY; RAT; ULTRASTRUCTURE;

AMYLOID; AMYLOID BETA-PEPTIDES; ANIMALS; CELL LINE; CELL SURVIVAL; DIFFUSION; DRUG DESIGN; LACTIC ACID; NANOCAPSULES; NANOCONJUGATES; NEURONS; PARTICLE SIZE; PC12 CELLS; PEPTIDE FRAGMENTS; PEPTIDES; POLYGLYCOLIC ACID; RATS;

EID: 84925358474     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.5b00915     Document Type: Article

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