Toxicity of protein aggregates in PC12 cells: 3-(4,5-dimethylthiazol-2- yl)-2,5-diphenyltetrazolium bromide assay

Methods in Enzymology

Volumn 309, Issue , 1999, Pages 716-723

  Shearman, Mark S ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AMYLOID BETA PROTEIN;

ANIMAL CELL; ARTICLE; CELL STRAIN; CYTOPATHOGENIC EFFECT; NEUROTOXICITY; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; RAT;

EID: 0032831760     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(99)09047-3     Document Type: Article

References (19)

1. C. L. Masters, G. Simms, N. A. Weinman, G. Multhaup, B. L. McDonald, and K. Beyreuther, Proc. Natl. Acad. Sci. U.S.A. 82, 4245 (1985).
2. D. M. A. Mann, P. O. Yates, and B. Marcyniuk, Neurosci. Lett. 56, 51 (1985).
3. R. E. Tanzi, P. H. St. George-Hyslop, and J. F. Gusella, Trends Neurosci. 12, 152 (1989).
4. D. J. Selkoe, Neuron 6, 487 (1991).
5. L. L. Iversen, R. M. Mortishire-Smith, S. J. Pollack, and M. S. Shearman, Biochem. J. 311, 1 (1995).
6. C. J. Pike, A. J. Walencewicz, C. G. Glabe, and C. W. Cotman, Eur. J. Pharmacol. 207, 367 (1991).
7. A. Lorenzo, B. Razzaboni, G. C. Weir, and B. A. Yankner, Nature 368, 756 (1994).
8. M. S. Shearman, C. I. Ragan, and L. L. Iversen, Proc. Natl. Acad. Sci. U.S.A. 91, 1470 (1994).
9. D. Schubert, C. Behl, R. Lesley, A. Brack, R. Dargusch, Y. Sagara, and H. Kimura, Proc. Natl. Acad. Sci. U.S.A. 92, 1989 (1995).
10. M. S. Shearman, S. R. Hawtin, and V. T. Tailor, J. Neurochem, 65, 218 (1995).
11. W. E. Klunk, J. W. Pettegrew, and D. J. Abraham, J. Histochem. Cytochem. 37, 1273 (1989).
12. M. B. Hansen, S. E. Nielson, and K. Berg, J. Immunol. Methods 119, 203 (1989).
13. A. H. Cory, Cancer Commun. 3, 207 (1991).
14. These are not true concentrations, as the peptide essentially exists as insoluble β-fibrillar aggregates. It is more correct to consider the activity of the peptides as an x-fold dilution of the stock solution.
15. Y. Liu and D. Schubert, J. Neurochem. 69, 2285 (1997)
16. T. F. Slater, B. Sawyer, and U. Sträuli, Biochim. Biophys. Acta 77, 383 (1963).
17. I. Kaneko, N. Yamada, Y. Sakaruba, M. Kamenosono, and S. Tutumi, J. Neurochem. 65, 2585 (1995).
18. C., Hertel, N., Hauser, R. Schubenel, B., Seilheimer, and J. A. Kemp, J. Neurochem. 67, 272 (1996).
19. Y. Liu, D. A. Peterson, H. Kimura, and D. Schubert, J. Neurochem. 69, 581 (1997).