Methylation at the CpG island shore region upregulates Nr3c1 promoter activity after early-life stress

Epigenetics

Volumn 10, Issue 3, 2015, Pages 247-257

  Bockmühl, Yvonne ^a   Patchev, Alexandre V ^a   Madejska, Arleta ^a   Hoffmann, Anke ^a   Sousa, Joao C ^b,c   Sousa, Nuno ^b,c   Holsboer, Florian ^a   Almeida, Osborne F X ^a   Spengler, Dietmar ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b UNIVERSITY OF MINHO   (Portugal)

^c UNIVERSITY OF MINHO   (Portugal)

Author keywords

CpG island shore; DNA methylation; Early life stress; Glucocorticoid receptor; Insulator; Yin yang

Indexed keywords

BISULFITE; CORTICOTROPIN RELEASING FACTOR; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; PLASMID DNA; SINGLE STRANDED DNA; TRANSCRIPTION FACTOR YY1; NR3C1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CHRONIC STRESS; COMPUTER MODEL; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA SEQUENCE; EARLY LIFE STRESS; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE MAPPING; GENE MUTATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; K562 CELL LINE; MALE; MOUSE; MTT ASSAY; NEGATIVE FEEDBACK; NONHUMAN; NUCLEOTIDE BINDING SITE; POLYMERASE CHAIN REACTION; PROMOTER REGION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; HYPOTHALAMUS; MENTAL STRESS; METABOLISM;

ANIMALS; CELLS, CULTURED; CPG ISLANDS; DNA METHYLATION; HYPOTHALAMUS; MALE; MICE, INBRED C57BL; PROMOTER REGIONS, GENETIC; RECEPTORS, GLUCOCORTICOID; STRESS, PSYCHOLOGICAL;

EID: 84925331860     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.1080/15592294.2015.1017199     Document Type: Article

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