Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 2, 2007, Pages 766-769

  Paulander, Wilhelm ^a   Pennhag, Alexandra ^a   Andersson, Dan I ^a,b   Maisnier Patin, Sophie ^a,c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACTINONIN; ANTIBIOTIC AGENT; FUSIDIC ACID; NALIDIXIC ACID; PSEUDOMONIC ACID; RIFAMPICIN; STREPTOMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL FITNESS; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DISEASE MODEL; ENTEROPATHY; GENE MUTATION; HOST PATHOGEN INTERACTION; NONHUMAN; PRIORITY JOURNAL; SALMONELLA ENTERICA; SALMONELLA TYPHIMURIUM; SEROTYPE;

ANIMALS; CAENORHABDITIS ELEGANS; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; MICE; SALMONELLA INFECTIONS, ANIMAL; SALMONELLA TYPHIMURIUM;

EID: 33846584956     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00615-06     Document Type: Article

References (28)

1. Aballay, A., and F. M. Ausubel. 2002. Caenorhabditis elegans as a host for the study of host-pathogen interactions. Curr. Opin. Microbiol. 5:97-101.
2. Aballay, A., P. Yorgey, and F. M. Ausubel. 2000. Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans. Curr. Biol. 10:1539-1542.
3. Andersson, D. I. 2003. Persistence of antibiotic resistant bacteria. Curr. Opin. Microbiol. 6:452-456.
4. Andersson, D. I., and B. R. Levin. 1999. The biological cost of antibiotic resistance. Curr. Opin. Microbiol. 2:489-493.
5. Beanan, M. J., and S. Strome. 1992. Characterization of a germ-line proliferation mutation in Caenorhabditis elegans. Development 116:755-766.
6. Björkholm, B., M. Sjolund, P. G. Falk, O. G. Berg, L. Engstrand, and D. I. Andersson. 2001. Mutation frequency and biological cost of antibiotic resistance in Helicobacter pylori. Proc. Natl. Acad. Sci. USA 98:14607-14612.
7. Björkman, J., D. Hughes, and D. I. Andersson. 1998. Virulence of antibiotic-resistant Salmonella typhimurium. Proc. Natl. Acad. Sci. USA 95:3949-3953.
8. Björkman, J., I. Nagaev, O. G. Berg, D. Hughes, and D. I. Andersson. 2000. Effects of environment on compensatory mutations to ameliorate costs of antibiotic resistance. Science 287:1479-1482.
9. Couillault, C., and J. J. Ewbank. 2002. Diverse bacteria are pathogens of Caenorhabditis elegans. Infect. Immun. 70:4705-4707.
10. Ernst, R. K., T. Guina, and S. I. Miller. 2001. Salmonella typhimurium outer membrane remodeling: role in resistance to host innate immunity. Microbes Infect. 3:1327-1334.
11. Garsin, D. A., C. D. Sifri, E. Mylonakis, X. Qin, K. V. Singh, B. E. Murray, S. B. Calderwood, and F. M. Ausubel. 2001. A simple model host for identifying gram-positive virulence factors. Proc. Natl. Acad. Sci. USA 98:10892-10897.
12. Hope, I. A. 1999. Caenorhabditis elegans: a practical approach, vol. 213. Oxford University Press, New York, NY.
13. Johanson, U., A. Aevarsson, A. Liljas, and D. Hughes. 1996. The dynamic structure of EF-G studied by fusidic acid resistance and internal revertants. J. Mol. Biol. 258:420-432.
14. Kaplan, E. L., and P. Meier. 1958. Nonparametric estimation from incomplete observations. J. Am. Statistical Assoc. 53:457-481.
15. Kurz, C. L., S. Chauvet, E. Andres, M. Aurouze, I. Vallet, G. P. Michel, M. Uh, J. Celli, A. Filloux, S. De Bentzmann, I. Steinmetz, J. A. Hoffmann, B. B. Finlay, J. P. Gorvel, D. Ferrandon, and J. J. Ewhank. 2003. Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening. EMBO J. 22:1451-1460.
16. Labrousse, A., S. Chauvet, C. Couillault, C. L. Kurz, and J. J. Ewbank. 2000. Caenorhabditis elegans is a model host for Salmonella typhimurium. Curr. Biol. 10:1543-1545.
17. Levin, B. R., V. Perrot, and N. Walker. 2000. Compensatory mutations, antibiotic resistance, and the population genetics of adaptive evolution in bacteria. Genetics 154:985-997.
18. Maisnier-Patin, S., and D. I. Andersson. 2004. Adaptation to the deleterious effects of antimicrobial drug resistance mutations by compensatory evolution. Res. Microbiol. 155:360-369.
19. Maisnier-Patin, S., O. G. Berg, L. Liljas, and D. I. Andersson. 2002. Compensatory adaptation to the deleterious effect of antibiotic resistance in Salmonella typhimurium. Mol. Microbiol. 46:355-366.
20. Nagaev, I., J. Björkman, D. I. Andersson, and D. Hughes. 2001. Biological cost and compensatory evolution in fusidic acid-resistant Staphylococcus aureus. Mol. Microbiol. 40:433-439.
21. Nilsson, A. I., A. Zorzet, A. Kanth, S. Dahlstrom, O. G. Berg, and D. I. Andersson. 2006. Reducing the fitness cost of antibiotic resistance by amplification of initiator tRNA genes. Proc. Natl. Acad. Sci. USA 103:6976-6981.
22. Reynolds, M. G. 2000. Compensatory evolution in rifampin-resistant Escherichia coli. Genetics 156:1471-1481.
23. Ruiz-Diez, B., P. Sanchez, F. Baquero, J. L. Martinez, and A. Navas. 2003. Differential interactions within the Caenorhabditis elegans-Pseudomonas aeruginosa pathogenesis model. J. Theor. Biol. 225:469-476.
24. Sanchez, P., J. F. Linares, B. Ruiz-Diez, E. Campanario, A. Navas, F. Baquero, and J. L. Martinez. 2002. Fitness of in vitro selected Pseudomonas aeruginosa nalB and nfxB multidrug resistant mutants. J. Antimicrob. Chemother. 50:657-664.
25. Schrag, S. J., V. Perrot, and B. R. Levin. 1997. Adaptation to the fitness costs of antibiotic resistance in Escherichia coli. Proc. R. Soc. Lond. B Biol. Sci. 264:1287-1291.
26. Sherman, D. R., K. Mdluli, M. J. Hickey, T. M. Arain, S. L. Morris, C. E. Barry III, and C. K. Stover. 1996. Compensatory ahpC gene expression in isoniazid-resistant Mycobacterium tuberculosis. Science 272:1641-1643.
27. Sifri, C. D., J. Begun, F. M. Ausubel, and S. B. Calderwood. 2003. Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis. Infect. Immun. 71:2208-2217.
28. Tenor, J. L., B. A. McCormick, F. M. Ausubel, and A. Aballay. 2004. Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. Curr. Biol. 14:1018-1024.