Application of mass spectrometry-based metabolomics in identification of early noninvasive biomarkers of alcohol-induced liver disease using mouse model

Advances in Experimental Medicine and Biology

Volumn 815, Issue , 2015, Pages 217-238

  Manna, Soumen K ^a   Thompson, Matthew D ^a   Gonzalez, Frank J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Alcohol induced liver disease; Biomarker; Genetic background; Indole 3 lactic acid; Metabolomics; Multivariate data analysis; Phenyllactic acid; Ppara null mouse; PPAR ; Steatosis; UPLC ESI QTOFMS

Indexed keywords

ALCOHOL; ATROLACTIC ACID; INDOLE 3 LACTIC ACID; LACTIC ACID DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; INDOLE DERIVATIVE; INDOLE-3-LACTIC ACID;

ALCOHOL CONSUMPTION; ALCOHOL INDUCED LIVER DISEASE; ALCOHOLISM; ARTICLE; DATA ANALYSIS; DEATH; DIAGNOSTIC TEST; DISEASE COURSE; DISEASE MARKER; DISEASE PREDISPOSITION; DRINKING BEHAVIOR; ELECTROSPRAY MASS SPECTROMETRY; HIGH RISK PATIENT; HUMAN; LIVER DISEASE; LIVER INJURY; MASS SPECTROMETRY; METABOLOMICS; MOLECULAR GENETICS; MULTIVARIATE ANALYSIS; NONHUMAN; PATHOGENESIS; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; QUANTITATIVE ANALYSIS; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINALYSIS; ANIMAL; DISEASE MODEL; LIVER DISEASES, ALCOHOLIC; MALE; MOUSE; PHYSIOLOGY; PROCEDURES; URINE;

ANIMALIA; MUS;

ANIMALS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; INDOLES; LIVER DISEASES, ALCOHOLIC; MALE; METABOLOMICS; MICE; PPAR ALPHA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84925292535     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-09614-8_13     Document Type: Article

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