C-terminal cleavage of human Foxp3 at a proprotein convertase motif abrogates its suppressive function

Scandinavian Journal of Immunology

Volumn 81, Issue 4, 2015, Pages 229-239

  Elhage, R ^a,b,c   Cherai M ^d   Levacher, B ^a,b,c   Darrasse Jeze, G ^e,f   Baillou, C ^a,f   Zhao, X ^a,b,c   Khatib, A M ^g,h   Piaggio, E ^f   Klatzmann, D ^a,b,c,d  

^a SORBONNE UNIVERSITÉ   (France)

^b CNRS   (France)

^c Sorbonne Université   (France)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f INSERM   (France)

^g UNIVERSITÉ DE BORDEAUX   (France)

^h Bordeaux Institute of Oncology   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FURIN; LENTIVIRUS VECTOR; PROPROTEIN CONVERTASE SUBTILISIN KEXIN 5; PROPROTEIN CONVERTASE SUBTILISIN KEXIN 7; SERINE PROTEINASE; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; ISOPROTEIN; PCSK7 PROTEIN, HUMAN; SUBTILISIN;

ADULT; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CD4+ T LYMPHOCYTE; EFFECTOR CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TRANSCRIPTOMICS; WESTERN BLOTTING; CELL PROLIFERATION; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENETIC TRANSFECTION; IMMUNOLOGY; MIDDLE AGED; YOUNG ADULT;

ADULT; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; HUMANS; MIDDLE AGED; PROPROTEIN CONVERTASES; PROTEIN ISOFORMS; SUBTILISINS; T-LYMPHOCYTES, REGULATORY; TRANSFECTION; YOUNG ADULT;

EID: 84925214643     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/sji.12275     Document Type: Article

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