PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway

Molecular and Cellular Biochemistry

Volumn 359, Issue 1-2, 2012, Pages 347-358

  Wu, Chun Yan ^a   Tang, Zhi Han ^a   Jiang, Lu ^a   Li, Xue Fei ^a   Jiang, Zhi Sheng ^a   Liu, Lu Shan ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Apoptosis; Caspase pathway; Human umbilical vein endothelial cells; Oxidized low density lipoprotein; Proprotein convertase subtilisin kexin type 9; Small interfering RNA

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CASPASE 3; CASPASE 9; LIPOFECTAMINE; OXIDIZED LOW DENSITY LIPOPROTEIN; PROPROTEIN CONVERTASE SUBTILISIN KEXIN 9; PROTEIN BAX; PROTEIN BCL 2; SERINE PROTEINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ATHEROGENESIS; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN TARGETING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CELLS, CULTURED; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIPOPROTEINS, LDL; PROPROTEIN CONVERTASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, SMALL INTERFERING; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION;

EID: 83555173282     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-1028-6     Document Type: Article

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