-
1
-
-
84934436966
-
Principles of Dicer substrate (D-siRNA) design and function
-
Amarzguioui M and Rossi JJ. 2008. Principles of Dicer substrate (D-siRNA) design and function. Methods Mol Biol, 442, 3-10.
-
(2008)
Methods Mol Biol
, vol.442
, pp. 3-10
-
-
Amarzguioui, M.1
Rossi, J.J.2
-
2
-
-
33845723241
-
Anaptamer doxorubicin physical conjugateas a novel targeted drug-delivery platform
-
Bagalkot V, Farokhzad OC, Langer R, Jon S. 2006. Anaptamer doxorubicin physical conjugateas a novel targeted drug-delivery platform. Angew Chem Int Ed Engl, 45, 8149-8152.
-
(2006)
Angew Chem Int Ed Engl
, vol.45
, pp. 8149-8152
-
-
Bagalkot, V.1
Farokhzad, O.C.2
Langer, R.3
Jon, S.4
-
3
-
-
67349167635
-
Discovery development of the G-rich oligonucleotide A.S1411 as a novel treatment for cancer
-
Bates PJ, Laber DA, Miller DM, Thomas SD, Trent JO. 2009. Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer. Exp Mol Pathol, 86, 151-164.
-
(2009)
Exp Mol Pathol.
, vol.86
, pp. 151-164
-
-
Bates, P.J.1
Laber, D.A.2
Miller, D.M.3
Thomas, S.D.4
Trent, J.O.5
-
4
-
-
84892941233
-
Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity
-
Berezhnoy A, Castro I, Levay A, Malek TR, Gilboa E. 2014. Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity. J Clin Invest, 124, 188-197.
-
(2014)
J Clin Invest
, vol.124
, pp. 188-197
-
-
Berezhnoy, A.1
Castro, I.2
Levay, A.3
Malek, T.R.4
Gilboa, E.5
-
5
-
-
84861584529
-
RNA interference therapeutics for cancer: Challenges and opportunities (Review)
-
Bora RS, Gupta D, Mukkur TK, Saini KS. 2012. RNA interference therapeutics for cancer: Challenges and opportunities (Review). Mol Med Rep, 6, 9-15.
-
(2012)
Mol Med Rep
, vol.6
, pp. 9-15
-
-
Bora, R.S.1
Gupta, D.2
Mukkur, T.K.3
Saini, K.S.4
-
6
-
-
77449133843
-
The role of let-7 in cell differentiation and cancer
-
Boyerinas B, Park SM, Hau A, Murmann AE, Peter ME. 2010. The role of let-7 in cell differentiation and cancer. Endocr Relat Cancer, 17, F19-36.
-
(2010)
Endocr Relat Cancer
, vol.17
, pp. F19-F36
-
-
Boyerinas, B.1
Park, S.M.2
Hau, A.3
Murmann, A.E.4
Peter, M.E.5
-
7
-
-
77956876990
-
Targeting cancer cells with nucleic acid aptamers
-
Cerchia L and de Franciscis V. 2010. Targeting cancer cells with nucleic acid aptamers. Trends Biotechnol, 28, 517-525.
-
(2010)
Trends Biotechnol
, vol.28
, pp. 517-525
-
-
Cerchia, L.1
de Franciscis, V.2
-
8
-
-
84870615894
-
Targeting Axl with an high-affinity inhibitory aptamer
-
Cerchia L, Esposito CL, Camorani S et al. 2012. Targeting Axl with an high-affinity inhibitory aptamer. Mol Ther, 20, 2291-2303.
-
(2012)
Mol Ther
, vol.20
, pp. 2291-2303
-
-
Cerchia, L.1
Esposito, C.L.2
Camorani, S.3
-
10
-
-
33745714275
-
Aptamer:toxin conjugates that specifically target prostate tumor cells
-
Chu TC, Marks J W 3rd, Lavery LA et al. 2006a. Aptamer:toxin conjugates that specifically target prostate tumor cells. Cancer Res, 66, 5989-5992.
-
(2006)
Cancer Res
, vol.66
, pp. 5989-5992
-
-
Chu, T.C.1
Marks, J.W.2
Lavery, L.A.3
-
11
-
-
33745128099
-
Aptamer mediated siRNA delivery
-
Chu TC, Twu KY, Ellington, AD, Levy M. 2006b. Aptamer mediated siRNA delivery. Nucleic Acids Res, 34, e73.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. e73
-
-
Chu, T.C.1
Twu, K.Y.2
Ellington, A.D.3
Levy, M.4
-
12
-
-
84874462055
-
Anticancer role of MUC1aptamer-miR-29b chimera in epithelial ovarian carcinoma cells through regulation of PTEN methylation
-
Dai F, Zhang Y, Zhu X, Shan N, Chen Y. 2012. Anticancer role of MUC1aptamer-miR-29b chimera in epithelial ovarian carcinoma cells through regulation of PTEN methylation. Target Oncol, 7, 217-225.
-
(2012)
Target Oncol
, vol.7
, pp. 217-225
-
-
Dai, F.1
Zhang, Y.2
Zhu, X.3
Shan, N.4
Chen, Y.5
-
13
-
-
70249110439
-
Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors
-
Dassie JP, Liu XY, Thomas GS et al. 2009. Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nat Biotechnol, 27, 839-849.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 839-849
-
-
Dassie, J.P.1
Liu, X.Y.2
Thomas, G.S.3
-
15
-
-
80054825739
-
New insight into clinical development of nucleic acid aptamers
-
Esposito CL, Catuogno S, de Franciscis V, Cerchia L. 2011. New insight into clinical development of nucleic acid aptamers. Discov Med, 11, 487-496.
-
(2011)
Discov Med
, vol.11
, pp. 487-496
-
-
Esposito, C.L.1
Catuogno, S.2
de Franciscis, V.3
Cerchia, L.4
-
16
-
-
84902144911
-
Multifunctional aptamer-miRNA conjugates for targeted cancer therapy
-
Esposito CL, Cerchia L, Catuogno S et al. 2014. Multifunctional aptamer-miRNA conjugates for targeted cancer therapy. Mol Ther 22, 1151-1163.
-
(2014)
Mol Ther
, vol.22
, pp. 1151-1163
-
-
Esposito, C.L.1
Cerchia, L.2
Catuogno, S.3
-
17
-
-
33646582037
-
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
-
Farokhzad OC, Cheng J, Teply BA et al. 2006. Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc Natl Acad Sci USA, 103, 6315-6320.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6315-6320
-
-
Farokhzad, O.C.1
Cheng, J.2
Teply, B.A.3
-
18
-
-
84911869868
-
Efficient delivery of micro RNA to bone-metastatic prostate tumors by using aptamer-conjugated atelocollagen in vitro and in vivo
-
Hao Z, Fan W, Hao J et al. 2014. Efficient delivery of micro RNA to bone-metastatic prostate tumors by using aptamer-conjugated atelocollagen in vitro and in vivo. Drug Deliv, 3, 1-8.
-
(2014)
Drug Deliv
, vol.3
, pp. 1-8
-
-
Hao, Z.1
Fan, W.2
Hao, J.3
-
19
-
-
84903759837
-
CTLA4 aptamer delivers STAT3 siRNA to tumor-associated and malignant T cells
-
Herrmann A, Priceman SJ, Kujawski MJ et al. 2014. CTLA4 aptamer delivers STAT3 siRNA to tumor-associated and malignant T cells. Clin Invest, 124, 2977-2987.
-
(2014)
Clin Invest
, vol.124
, pp. 2977-2987
-
-
Herrmann, A.1
Priceman, S.J.2
Kujawski, M.J.3
-
21
-
-
81855224576
-
MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therap
-
Kasinski AL and Slack FJ. 2011. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nature Reviews Cancer 11, 849-864
-
(2011)
Nature Reviews Cancer
, vol.11
, pp. 849-864
-
-
Kasinski, A.L.1
Slack, F.J.2
-
22
-
-
79954650563
-
State-of-the-art gene-based therapies: the road ahead
-
Kay MA. 2011. State-of-the-art gene-based therapies: the road ahead. Nature Reviews Genetics, 12, 316-328.
-
(2011)
Nature Reviews Genetics
, vol.12
, pp. 316-328
-
-
Kay, M.A.1
-
23
-
-
82855175161
-
Molecular imaging of a cancer-targeting theragnostics probe using a nucleolin aptamer- and microRNA-221 molecular beacon-conjugated nanoparticle
-
Kim JK, Choi KJ, Lee M, Jo MH, Kim S. 2012. Molecular imaging of a cancer-targeting theragnostics probe using a nucleolin aptamer- and microRNA-221 molecular beacon-conjugated nanoparticle. Biomaterials, 33, 207-217.
-
(2012)
Biomaterials
, vol.33
, pp. 207-217
-
-
Kim, J.K.1
Choi, K.J.2
Lee, M.3
Jo, M.H.4
Kim, S.5
-
24
-
-
70450247207
-
Mucins in cancer: function, prognosis and therapy
-
Kufe DW. 2009. Mucins in cancer: function, prognosis and therapy. Nat Rev Cancer, 9, 874-885.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 874-885
-
-
Kufe, D.W.1
-
25
-
-
84894952867
-
Synergistic inhibition of lung cancer cell invasion, tumor growth and angiogenesis using aptamer-siRNA chimeras
-
Lai WY, Wang WY, Chang YC, Chang CJ, Yang PC, Peck K. 2014. Synergistic inhibition of lung cancer cell invasion, tumor growth and angiogenesis using aptamer-siRNA chimeras. Biomaterials, 35, 2905-2914.
-
(2014)
Biomaterials
, vol.35
, pp. 2905-2914
-
-
Lai, W.Y.1
Wang, W.Y.2
Chang, Y.C.3
Chang, C.J.4
Yang, P.C.5
Peck, K.6
-
26
-
-
84893739355
-
Nucleolin-targeting liposomes guided by aptamer AS1411 for the delivery of siRNA for the treatment of malignant melanomas
-
Li L, Hou J, Liu X et al. 2014. Nucleolin-targeting liposomes guided by aptamer AS1411 for the delivery of siRNA for the treatment of malignant melanomas. Biomaterials. 2014, 35, 3840-3850.
-
(2014)
Biomaterials. 2014
, vol.35
, pp. 3840-3850
-
-
Li, L.1
Hou, J.2
Liu, X.3
-
27
-
-
84866883611
-
Reversal of paclitaxel resistance in epithelial ovarian carcinoma cells by a MUC1 aptamerlet-7i chimera
-
Liu N, Zhou C, Zhao J, Chen Y. 2012. Reversal of paclitaxel resistance in epithelial ovarian carcinoma cells by a MUC1 aptamerlet-7i chimera. Cancer Invest, 30, 577-82.
-
(2012)
Cancer Invest
, vol.30
, pp. 577-582
-
-
Liu, N.1
Zhou, C.2
Zhao, J.3
Chen, Y.4
-
28
-
-
0037099536
-
Identification and characterization of nuclease stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen
-
Lupold SE, Hicke BJ, Lin Y, Coffey DS. 2002. Identification and characterization of nuclease stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen. Cancer Res, 62, 4029-4033.
-
(2002)
Cancer Res
, vol.62
, pp. 4029-4033
-
-
Lupold, S.E.1
Hicke, B.J.2
Lin, Y.3
Coffey, D.S.4
-
29
-
-
33747031960
-
Cell typespecific delivery of siRNAs with aptamer-siRNA chimeras
-
McNamara JO 2nd, Andrechek ER, Wang Y et al. 2006. Cell typespecific delivery of siRNAs with aptamer-siRNA chimeras. Nat Biotechnol, 24, 1005-1015.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1005-1015
-
-
McNamara J.O, 2nd.1
Andrechek, E.R.2
Wang, Y.3
-
30
-
-
79957920185
-
Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts
-
Ni X, Zhang Y, Ribas J et al. 2011. Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts. J Clin Invest, 121, 2383-2390.
-
(2011)
J Clin Invest
, vol.121
, pp. 2383-2390
-
-
Ni, X.1
Zhang, Y.2
Ribas, J.3
-
31
-
-
77952380547
-
Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decoy
-
Pastor F, Kolonias D, Giangrande PH, Gilboa E. 2010. Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decoy. Nature, 465, 227- 230.
-
(2010)
Nature
, vol.465
, pp. 227-230
-
-
Pastor, F.1
Kolonias, D.2
Giangrande, P.H.3
Gilboa, E.4
-
32
-
-
27744506761
-
Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
-
Rand TA, Petersen S, Du F, Wang X. 2005. Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell, 123, 621-629.
-
(2005)
Cell
, vol.123
, pp. 621-629
-
-
Rand, T.A.1
Petersen, S.2
Du, F.3
Wang, X.4
-
33
-
-
84882253822
-
RNA interference and personalized cancer therapy
-
Rao DD, Wang Z, Senzer N, Nemunaitis J. 2013. RNA interference and personalized cancer therapy. Discov Med, 15, 101-110.
-
(2013)
Discov Med
, vol.15
, pp. 101-110
-
-
Rao, D.D.1
Wang, Z.2
Senzer, N.3
Nemunaitis, J.4
-
34
-
-
77249096959
-
Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook
-
Shukla S, Sumaria CS and Pradeepkumar PI. 2010. Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook. ChemMedChem, 5, 328-349.
-
(2010)
ChemMedChem
, vol.5
, pp. 328-349
-
-
Shukla, S.1
Sumaria, C.S.2
Pradeepkumar, P.I.3
-
35
-
-
84901547045
-
DNA aptamers that target human glioblastoma multiforme cells overexpressing epidermal growth factor receptor variant III in vitro
-
Tan Y, Shi YS, Wu XD et al. 2013. DNA aptamers that target human glioblastoma multiforme cells overexpressing epidermal growth factor receptor variant III in vitro. Acta Pharmacol Sin, 34, 1491-1498.
-
(2013)
Acta Pharmacol Sin
, vol.34
, pp. 1491-1498
-
-
Tan, Y.1
Shi, Y.S.2
Wu, X.D.3
-
36
-
-
84864447484
-
Delivery of chemosensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers
-
Thiel KW, Hernandez L, Dassie JP et al. 2012. Delivery of chemosensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers. Nucleic Acids Res, 40, 6319-6337.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 6319-6337
-
-
Thiel, K.W.1
Hernandez, L.2
Dassie, J.P.3
-
37
-
-
84897948088
-
Oncology drug discovery: planning a turn around
-
Toniatti C, Jones P, Graham H, Pagliara B, Draetta G. 2014. Oncology drug discovery: planning a turn around. Cancer Discov, 4, 397-404.
-
(2014)
Cancer Discov
, vol.4
, pp. 397-404
-
-
Toniatti, C.1
Jones, P.2
Graham, H.3
Pagliara, B.4
Draetta, G.5
-
38
-
-
0025194307
-
Systematic Evolution of Ligands by Exponential Enrichment RNA Ligands to Bacteriophage T4 Polymerase
-
Tuek C and Gold L. 1990 Systematic Evolution of Ligands by Exponential Enrichment RNA Ligands to Bacteriophage T4 Polymerase. Science, 249, 505-510.
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuek, C.1
Gold, L.2
-
39
-
-
84878630603
-
RNAi therapeutics and applications of microRNAs in cancer treatment
-
Uchino K, Ochiya T, Takeshita F. 2013. RNAi therapeutics and applications of microRNAs in cancer treatment. Jpn J Clin Oncol, 43, 596-607.
-
(2013)
Jpn J Clin Oncol
, vol.43
, pp. 596-607
-
-
Uchino, K.1
Ochiya, T.2
Takeshita, F.3
-
40
-
-
84901804034
-
Multivalent comb-type aptamer-siRNA conjugates for efficient and selective intracellular delivery
-
Yoo H, Jung H, Kim SA, Mok H. 2014. Multivalent comb-type aptamer-siRNA conjugates for efficient and selective intracellular delivery. Chem Commun (Camb), 50, 6765-6767.
-
(2014)
Chem Commun (Camb)
, vol.50
, pp. 6765-6767
-
-
Yoo, H.1
Jung, H.2
Kim, S.A.3
Mok, H.4
-
41
-
-
84884601713
-
Aptamer-Conjugated Nanorods for Targeted Photothermal Therapy of Prostate Cancer Stem Cells
-
Wang J, Sefah K, Altman MB et al. 2013. Aptamer-Conjugated Nanorods for Targeted Photothermal Therapy of Prostate Cancer Stem Cells. Chem Asian J, 8, 2417-2422.
-
(2013)
Chem Asian J
, vol.8
, pp. 2417-2422
-
-
Wang, J.1
Sefah, K.2
Altman, M.B.3
-
42
-
-
84903133224
-
RNAi Therapies: Drugging the Undruggable
-
Wu SY, Lopez-Berestein G, Calin GA, Sood AK. 2014. RNAi Therapies: Drugging the Undruggable. Sci. Transl. Med, 6, 240ps7.
-
(2014)
Sci. Transl. Med
, vol.6
, pp. 240-247
-
-
Wu, S.Y.1
Lopez-Berestein, G.2
Calin, G.A.3
Sood, A.K.4
-
43
-
-
84862833395
-
Second-generation aptamerconjugated PSMA-targeted delivery system for prostate cancer therapy
-
Wu X, Ding B, Gao J et al. 2011. Second-generation aptamerconjugated PSMA-targeted delivery system for prostate cancer therapy. Int J Nanomedicine, 6, 1747-1756.
-
(2011)
Int J Nanomedicine
, vol.6
, pp. 1747-1756
-
-
Wu, X.1
Ding, B.2
Gao, J.3
-
44
-
-
55449127119
-
Cellspecific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2
-
Wullner U, Neef I, Eller A, Kleines M, Tur MK, Barth S. 2008. Cellspecific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2. Curr Cancer Drug Targets, 8, 554-565.
-
(2008)
Curr Cancer Drug Targets
, vol.8
, pp. 554-565
-
-
Wullner, U.1
Neef, I.2
Eller, A.3
Kleines, M.4
Tur, M.K.5
Barth, S.6
-
45
-
-
84928251100
-
-
Zhang X, Liang H, Tan Y, Wu X, Li S, Shi Y. 2014. A U87- EGFRvIII cell-specific aptamer mediates small interfering RNA delivery Biomed Rep, 2, 495-499.
-
(2014)
A U87- EGFRvIII cell-specific aptamer mediates small interfering RNA delivery Biomed Rep
, vol.2
, pp. 495-499
-
-
Zhang, X.1
Liang, H.2
Tan, Y.3
Wu, X.4
Li, S.5
Shi, Y.6
-
46
-
-
77954362096
-
Aptamer-targeted cell-specific RNA interference
-
Zhou J and Rossi JJ. 2010. Aptamer-targeted cell-specific RNA interference. Silence, 1, 4.
-
(2010)
Silence
, vol.1
, pp. 4
-
-
Zhou, J.1
Rossi, J.J.2
-
47
-
-
84872863485
-
Nanoparticle- Based Delivery of RNAi Therapeutics: Progress and Challenges
-
Zhou J, Shum KT, Burnett JC, Rossi JJ. 2013a. Nanoparticle- Based Delivery of RNAi Therapeutics: Progress and Challenges. Pharmaceuticals (Basel), 6, 85-107.
-
(2013)
Pharmaceuticals (Basel)
, vol.6
, pp. 85-107
-
-
Zhou, J.1
Shum, K.T.2
Burnett, J.C.3
Rossi, J.J.4
-
48
-
-
84871919249
-
Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge
-
Zhou J, Neff CP, Swiderski P et al. 2013b. Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge. Mol Ther, 21, 192-200.
-
(2013)
Mol Ther
, vol.21
, pp. 192-200
-
-
Zhou, J.1
Neff, C.P.2
Swiderski, P.3
|