-
1
-
-
84870166429
-
The unfolded protein response in secretory cell function
-
Moore KA, Hollien J (2012) The unfolded protein response in secretory cell function. Annu Rev Genet 46: 165-183.
-
(2012)
Annu Rev Genet
, vol.46
, pp. 165-183
-
-
Moore, K.A.1
Hollien, J.2
-
2
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
DOI 10.1038/nrm2199, PII NRM2199
-
Ron D, Walter P (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8: 519-529. (Pubitemid 46985379)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.7
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
3
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
Walter P, Ron D (2011) The unfolded protein response: from stress pathway to homeostatic regulation. Science 334: 1081-1086.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
4
-
-
0029903049
-
Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus
-
Shamu CE, Walter P (1996) Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus. Embo J 15: 3028-3039.
-
(1996)
Embo J
, vol.15
, pp. 3028-3039
-
-
Shamu, C.E.1
Walter, P.2
-
5
-
-
0032525990
-
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
-
Tirasophon W, Welihinda AA, Kaufman RJ (1998) A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev 12: 1812-1824. (Pubitemid 28304334)
-
(1998)
Genes and Development
, vol.12
, Issue.12
, pp. 1812-1824
-
-
Tirasophon, W.1
Welihinda, A.A.2
Kaufman, R.J.3
-
6
-
-
0037166303
-
The protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain
-
DOI 10.1074/jbc.M112454200
-
Liu CY, Wong HN, Schauerte JA, Kaufman RJ (2002) The protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain. J Biol Chem 277: 18346-18356. (Pubitemid 34952379)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.21
, pp. 18346-18356
-
-
Liu, C.Y.1
Wong, H.N.2
Schauerte, J.A.3
Kaufman, R.J.4
-
7
-
-
30044432596
-
On the mechanism of sensing unfolded protein in the endoplasmic reticulum
-
DOI 10.1073/pnas.0509487102
-
Credle JJ, Finer-Moore JS, Papa FR, Stroud RM, Walter P (2005) On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc Natl Acad Sci U S A 102: 18773-18784. (Pubitemid 43049523)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.52
, pp. 18773-18784
-
-
Credle, J.J.1
Finer-Moore, J.S.2
Papa, F.R.3
Stroud, R.M.4
Walter, P.5
-
8
-
-
80053369081
-
Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response
-
Gardner BM, Walter P (2011) Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response. Science 333: 1891-1894.
-
(2011)
Science
, vol.333
, pp. 1891-1894
-
-
Gardner, B.M.1
Walter, P.2
-
9
-
-
0030297537
-
A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response
-
DOI 10.1016/S0092-8674(00)81360-4
-
Cox JS, Walter P (1996) A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response. Cell 87: 391-404. (Pubitemid 26374314)
-
(1996)
Cell
, vol.87
, Issue.3
, pp. 391-404
-
-
Cox, J.S.1
Walter, P.2
-
10
-
-
0030954870
-
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response
-
DOI 10.1016/S0092-8674(00)80369-4
-
Sidrauski C, Walter P (1997) The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell 90: 1031-1039. (Pubitemid 27408517)
-
(1997)
Cell
, vol.90
, Issue.6
, pp. 1031-1039
-
-
Sidrauski, C.1
Walter, P.2
-
11
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
DOI 10.1016/S0092-8674(01)00611-0
-
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107: 881-891. (Pubitemid 34084979)
-
(2001)
Cell
, vol.107
, Issue.7
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
12
-
-
18244405070
-
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development
-
DOI 10.1016/S0092-8674(01)00612-2
-
Shen X, Ellis RE, Lee K, Liu CY, Yang K, et al. (2001) Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development. Cell 107: 893-903. (Pubitemid 34084980)
-
(2001)
Cell
, vol.107
, Issue.7
, pp. 893-903
-
-
Shen, X.1
Ellis, R.E.2
Lee, K.3
Liu, C.-Y.4
Yang, K.5
Solomon, A.6
Yoshida, H.7
Morimoto, R.8
Kurnit, D.M.9
Mori, K.10
Kaufman, R.J.11
-
13
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
DOI 10.1038/415092a
-
Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, et al. (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415: 92-96. (Pubitemid 34062456)
-
(2002)
Nature
, vol.415
, Issue.6867
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
14
-
-
33846219134
-
Unfolded protein response in a Drosophila model for retinal degeneration
-
DOI 10.1038/sj.emboj.7601477, PII 7601477
-
Ryoo HD, Domingos PM, Kang MJ, Steller H (2007) Unfolded protein response in a Drosophila model for retinal degeneration. Embo J 26: 242-252. (Pubitemid 46094715)
-
(2007)
EMBO Journal
, vol.26
, Issue.1
, pp. 242-252
-
-
Ryoo, H.D.1
Domingos, P.M.2
Kang, M.-J.3
Steller, H.4
-
15
-
-
33846829603
-
Ire1 regulated XBP1 mRNA splicing is essential for the unfolded protein response (UPR) in Drosophila melanogaster
-
DOI 10.1016/j.bbrc.2007.01.056, PII S0006291X07001027
-
Plongthongkum N, Kullawong N, Panyim S, Tirasophon W (2007) Ire1 regulated XBP1 mRNA splicing is essential for the unfolded protein response (UPR) in Drosophila melanogaster. Biochem Biophys Res Commun 354: 789-794. (Pubitemid 46201805)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.354
, Issue.3
, pp. 789-794
-
-
Plongthongkum, N.1
Kullawong, N.2
Panyim, S.3
Tirasophon, W.4
-
16
-
-
0043193876
-
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells
-
DOI 10.1073/pnas.1334037100
-
Lee AH, Iwakoshi NN, Anderson KC, Glimcher LH (2003) Proteasome inhibitors disrupt the unfolded protein response in myeloma cells. Proc Natl Acad Sci U S A 100: 9946-9951. (Pubitemid 37087048)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.17
, pp. 9946-9951
-
-
Lee, A.-H.1
Iwakoshi, N.N.2
Anderson, K.C.3
Glimcher, L.H.4
-
17
-
-
45849137877
-
Regulation of hepatic lipogenesis by the transcription factor XBP1
-
DOI 10.1126/science.1158042
-
Lee AH, Scapa EF, Cohen DE, Glimcher LH (2008) Regulation of hepatic lipogenesis by the transcription factor XBP1. Science 320: 1492-1496. (Pubitemid 351929428)
-
(2008)
Science
, vol.320
, Issue.5882
, pp. 1492-1496
-
-
Lee, A.-H.1
Scapa, E.F.2
Cohen, D.E.3
Glimcher, L.H.4
-
18
-
-
34548172495
-
Transcriptional Induction of Mammalian ER Quality Control Proteins Is Mediated by Single or Combined Action of ATF6alpha and XBP1
-
DOI 10.1016/j.devcel.2007.07.018, PII S1534580707003000
-
Yamamoto K, Sato T, Matsui T, Sato M, Okada T, et al. (2007) Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. Dev Cell 13: 365-376. (Pubitemid 47308680)
-
(2007)
Developmental Cell
, vol.13
, Issue.3
, pp. 365-376
-
-
Yamamoto, K.1
Sato, T.2
Matsui, T.3
Sato, M.4
Okada, T.5
Yoshida, H.6
Harada, A.7
Mori, K.8
-
19
-
-
32644432826
-
pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response
-
DOI 10.1083/jcb.200508145
-
Yoshida H, Oku M, Suzuki M, Mori K (2006) pXBP1(U) encoded in XBP1 premRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response. J Cell Biol 172: 565-575. (Pubitemid 43243877)
-
(2006)
Journal of Cell Biology
, vol.172
, Issue.4
, pp. 565-575
-
-
Yoshida, H.1
Oku, M.2
Suzuki, M.3
Mori, K.4
-
20
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
DOI 10.1126/science.1129631
-
Hollien J, Weissman JS (2006) Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 313: 104-107. (Pubitemid 44051264)
-
(2006)
Science
, vol.313
, Issue.5783
, pp. 104-107
-
-
Hollien, J.1
Weissman, J.S.2
-
21
-
-
84859587957
-
The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule
-
Cross BC, Bond PJ, Sadowski PG, Jha BK, Zak J, et al. (2012) The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule. Proc Natl Acad Sci U S A 109: E869-878.
-
(2012)
Proc Natl Acad Sci U S a
, vol.109
-
-
Cross, B.C.1
Bond, P.J.2
Sadowski, P.G.3
Jha, B.K.4
Zak, J.5
-
22
-
-
84875857579
-
The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis
-
Kimmig P, Diaz M, Zheng J, Williams CC, Lang A, et al. (2012) The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis. Elife 1: e00048.
-
(2012)
Elife
, vol.1
-
-
Kimmig, P.1
Diaz, M.2
Zheng, J.3
Williams, C.C.4
Lang, A.5
-
23
-
-
68549092781
-
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
-
Hollien J, Lin JH, Li H, Stevens N, Walter P, et al. (2009) Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol 186: 323-331.
-
(2009)
J Cell Biol
, vol.186
, pp. 323-331
-
-
Hollien, J.1
Lin, J.H.2
Li, H.3
Stevens, N.4
Walter, P.5
-
24
-
-
84901053043
-
Physiological roles of regulated Ire1 dependent decay
-
Coelho DS, Domingos PM (2014) Physiological roles of regulated Ire1 dependent decay. Front Genet 5: 76.
-
(2014)
Front Genet
, vol.5
, pp. 76
-
-
Coelho, D.S.1
Domingos, P.M.2
-
26
-
-
84871911924
-
Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells
-
Gaddam D, Stevens N, Hollien J (2013) Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells. Mol Biol Cell 24: 14-20.
-
(2013)
Mol Biol Cell
, vol.24
, pp. 14-20
-
-
Gaddam, D.1
Stevens, N.2
Hollien, J.3
-
27
-
-
84880641508
-
Evolution of the unfolded protein response
-
Hollien J (2013) Evolution of the unfolded protein response. Biochim Biophys Acta 1833: 2458-2463.
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 2458-2463
-
-
Hollien, J.1
-
28
-
-
84884278268
-
Regulation of sumo mRNA during endoplasmic reticulum stress
-
Moore KA, Plant JJ, Gaddam D, Craft J, Hollien J (2013) Regulation of sumo mRNA during endoplasmic reticulum stress. PLoS One 8: e75723.
-
(2013)
PLoS One
, vol.8
-
-
Moore, K.A.1
Plant, J.J.2
Gaddam, D.3
Craft, J.4
Hollien, J.5
-
29
-
-
59649092854
-
Messenger RNA targeting to endoplasmic reticulum stress signalling sites
-
Aragon T, van Anken E, Pincus D, Serafimova IM, Korennykh AV, et al. (2009) Messenger RNA targeting to endoplasmic reticulum stress signalling sites. Nature 457: 736-740.
-
(2009)
Nature
, vol.457
, pp. 736-740
-
-
Aragon, T.1
Van Anken, E.2
Pincus, D.3
Serafimova, I.M.4
Korennykh, A.V.5
-
30
-
-
64749103329
-
Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA
-
Yanagitani K, Imagawa Y, Iwawaki T, Hosoda A, Saito M, et al. (2009) Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA. Mol Cell 34: 191-200.
-
(2009)
Mol Cell
, vol.34
, pp. 191-200
-
-
Yanagitani, K.1
Imagawa, Y.2
Iwawaki, T.3
Hosoda, A.4
Saito, M.5
-
31
-
-
79551629027
-
Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA
-
Yanagitani K, Kimata Y, Kadokura H, Kohno K (2011) Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA. Science 331: 586-589.
-
(2011)
Science
, vol.331
, pp. 586-589
-
-
Yanagitani, K.1
Kimata, Y.2
Kadokura, H.3
Kohno, K.4
-
32
-
-
33846847860
-
The xbp-1 gene is essential for development in Drosophila
-
DOI 10.1007/s00427-006-0124-1
-
Souid S, Lepesant JA, Yanicostas C (2007) The xbp-1 gene is essential for development in Drosophila. Dev Genes Evol 217: 159-167. (Pubitemid 46206508)
-
(2007)
Development Genes and Evolution
, vol.217
, Issue.2
, pp. 159-167
-
-
Souid, S.1
Lepesant, J.-A.2
Yanicostas, C.3
-
33
-
-
77957352000
-
Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila
-
Griciuc A, Aron L, Roux MJ, Klein R, Giangrande A, et al. (2010) Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila. PLoS Genet 6.
-
(2010)
PLoS Genet
, vol.6
-
-
Griciuc, A.1
Aron, L.2
Roux, M.J.3
Klein, R.4
Giangrande, A.5
-
34
-
-
70350131291
-
Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation
-
Kang MJ, Ryoo HD (2009) Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation. Proc Natl Acad Sci U S A 106: 17043-17048.
-
(2009)
Proc Natl Acad Sci U S a
, vol.106
, pp. 17043-17048
-
-
Kang, M.J.1
Ryoo, H.D.2
-
35
-
-
65649146419
-
ER stress protects from retinal degeneration
-
Mendes CS, Levet C, Chatelain G, Dourlen P, Fouillet A, et al. (2009) ER stress protects from retinal degeneration. Embo J 28: 1296-1307.
-
(2009)
Embo J
, vol.28
, pp. 1296-1307
-
-
Mendes, C.S.1
Levet, C.2
Chatelain, G.3
Dourlen, P.4
Fouillet, A.5
-
36
-
-
84887609926
-
Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila
-
Coelho DS, Cairrao F, Zeng X, Pires E, Coelho AV, et al. (2013) Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila. Cell Rep 5: 791-801.
-
(2013)
Cell Rep
, vol.5
, pp. 791-801
-
-
Coelho, D.S.1
Cairrao, F.2
Zeng, X.3
Pires, E.4
Coelho, A.V.5
-
37
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand AH, Perrimon N (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415. (Pubitemid 23214028)
-
(1993)
Development
, vol.118
, Issue.2
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
38
-
-
84877833331
-
A modified UPR stress sensing system reveals a novel tissue distribution of IRE1/XBP1 activity during normal Drosophila development
-
Sone M, Zeng X, Larese J, Ryoo HD (2012) A modified UPR stress sensing system reveals a novel tissue distribution of IRE1/XBP1 activity during normal Drosophila development. Cell Stress Chaperones 18: 307-319.
-
(2012)
Cell Stress Chaperones
, vol.18
, pp. 307-319
-
-
Sone, M.1
Zeng, X.2
Larese, J.3
Ryoo, H.D.4
-
39
-
-
79956036398
-
The ER stress factor XBP1s prevents amyloid-beta neurotoxicity
-
Casas-Tinto S, Zhang Y, Sanchez-Garcia J, Gomez-Velazquez M, Rincon-Limas DE, et al. (2011) The ER stress factor XBP1s prevents amyloid-beta neurotoxicity. Hum Mol Genet 20: 2144-2160.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 2144-2160
-
-
Casas-Tinto, S.1
Zhang, Y.2
Sanchez-Garcia, J.3
Gomez-Velazquez, M.4
Rincon-Limas, D.E.5
-
40
-
-
34147142514
-
Unfolded protein response in Drosophila: Why another model can make it fly
-
Ryoo HD, Steller H (2007) Unfolded protein response in Drosophila: why another model can make it fly. Cell Cycle 6: 830-835. a Tecnologia a Tecnologia a Tecnologia e a Tecnologia
-
(2007)
Cell Cycle
, vol.6
, pp. 830-835
-
-
Ryoo, H.D.1
Steller, H.2
|