Regulation of Sumo mRNA during Endoplasmic Reticulum Stress

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Moore, Kristin A ^a   Plant, Joshua J ^a   Gaddam, Deepika ^a   Craft, Jonathan ^a   Hollien, Julie ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN IRE1; PROTEIN PERK; PROTEIN SMT3; SUMO PROTEIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSOL; DROSOPHILA; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME LOCALIZATION; GENE EXPRESSION REGULATION; INSECT CELL; NONHUMAN; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN MISFOLDING; REGULATED IRE1 DEPENDENT DECAY; RNA DEGRADATION; RNA SPLICING; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

ANIMALS; CELL LINE; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; REPRESSOR PROTEINS; RNA STABILITY; RNA, MESSENGER; UNFOLDED PROTEIN RESPONSE;

EID: 84884278268     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075723     Document Type: Article

References (36)

1. Moore KA, Hollien J, (2012) The unfolded protein response in secretory cell function. Annu Rev Genet 46: 165-183.
2. Walter P, Ron D, (2011) The unfolded protein response: from stress pathway to homeostatic regulation. Science 334: 1081-1086.
3. Wang S, Kaufman RJ, (2012) The impact of the unfolded protein response on human disease. J Cell Biol 197: 857-867.
4. Harding HP, Zhang Y, Ron D, (1999) Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397: 271-274.
5. Shi Y, Vattem KM, Sood R, An J, Liang J, et al. (1998) Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. Mol Cell Biol 18: 7499-7509.
6. Sood R, Porter AC, Ma K, Quilliam LA, Wek RC, (2000) Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress. Biochem J 346 Pt 2: 281-293.
7. Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D, (2000) Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell 5: 897-904.
8. Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, et al. (2000) Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell. United States. pp. 1099-1108.
9. Credle JJ, Finer-Moore JS, Papa FR, Stroud RM, Walter P, (2005) On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc Natl Acad Sci U S A 102: 18773-18784.
10. Cox JS, Shamu CE, Walter P, (1993) Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 73: 1197-1206.
11. Mori K, Ma W, Gething MJ, Sambrook J, (1993) A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 74: 743-756.
12. Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, et al. (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415: 92-96.
13. Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell. United States. pp. 881-891.
14. Haze K, Yoshida H, Yanagi H, Yura T, Mori K, (1999) Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol Biol Cell 10: 3787-3799.
15. Lee AH, Iwakoshi NN, Glimcher LH, (2003) XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol 23: 7448-7459.
16. Lu PD, Harding HP, Ron D (2004) Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response. J Cell Biol. United States. pp. 27-33.
17. Hollien J, Weissman JS, (2006) Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 313: 104-107.
18. Hollien J, Lin JH, Li H, Stevens N, Walter P, et al. (2009) Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol 186: 323-331.
19. Han D, Lerner AG, Vande Walle L, Upton JP, Xu W, et al. (2009) IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell. United States. pp. 562-575.
20. Gaddam D, Stevens N, Hollien J, (2013) Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells. Mol Biol Cell 24: 14-20.
21. Kimmig P, Diaz M, Zheng J, Williams CC, Lang A, et al. (2012) The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis. elife 1: e00048.
22. Hur KY, So JS, Ruda V, Frank-Kamenetsky M, Fitzgerald K, et al. (2012) IRE1alpha activation protects mice against acetaminophen-induced hepatotoxicity. J Exp Med. United States. pp. 307-318.
23. Stephens SB, Dodd RD, Lerner RS, Pyhtila BM, Nicchitta CV, (2008) Analysis of mRNA partitioning between the cytosol and endoplasmic reticulum compartments of mammalian cells. Methods Mol Biol 419: 197-214.
24. Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, et al. (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415: 92-96.
25. Kawai T, Fan J, Mazan-Mamczarz K, Gorospe M (2004) Global mRNA stabilization preferentially linked to translational repression during the endoplasmic reticulum stress response. Mol Cell Biol. United States. pp. 6773-6787.
26. Majumder M, Huang C, Snider MD, Komar AA, Tanaka J, et al. (2012) A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation. Mol Cell Biol. United States. pp. 992-1003.
27. Kawahara T, Yanagi H, Yura T, Mori K, (1998) Unconventional splicing of HAC1/ERN4 mRNA required for the unfolded protein response. Sequence-specific and non-sequential cleavage of the splice sites. J Biol Chem 273: 1802-1807.
28. Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, et al. (2003) Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol 4: 321-329.
29. Gonzalez TN, Sidrauski C, Dorfler S, Walter P, (1999) Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway. Embo j 18: 3119-3132.
30. Flotho A, Melchior F, (2013) Sumoylation: a regulatory protein modification in health and disease. Annu Rev Biochem 82: 357-385.
31. Chen H, Qi L, (2010) SUMO modification regulates the transcriptional activity of XBP1. Biochem J 429: 95-102.
32. Jiang Z, Fan Q, Zhang Z, Zou Y, Cai R, et al. (2012) SENP1 deficiency promotes ER stress-induced apoptosis by increasing XBP1 SUMOylation. Cell Cycle 11: 1118-1122.
33. Garrey JL, Lee YY, Au HH, Bushell M, Jan E, (2010) Host and viral translational mechanisms during cricket paralysis virus infection. J Virol 84: 1124-1138.
34. Lee YY, Cevallos RC, Jan E, (2009) An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation. J Biol Chem 284: 6661-6673.
35. Kimmig P, Diaz M, Zheng J, Williams CC, Lang A, et al. (2012) The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis. Elife. United States. pp. e00048.
36. So JS, Hur KY, Tarrio M, Ruda V, Frank-Kamenetsky M, et al. (2012) Silencing of lipid metabolism genes through IRE1alpha-mediated mRNA decay lowers plasma lipids in mice. Cell Metab 16: 487-499.