pH-sensitive nanoparticles of poly(L-histidine)-poly(lactide-co-glycolide)-tocopheryl polyethylene glycol succinate for anti-tumor drug delivery

Acta Biomaterialia

Volumn 11, Issue 1, 2015, Pages 137-150

  Li, Zhen ^a,b   Qiu, Lipeng ^a   Chen, Qing ^a   Hao, Tangna ^b   Qiao, Mingxi ^a   Zhao, Haixia ^a   Zhang, Jie ^a   Hu, Haiyang ^a   Zhao, Xiuli ^a   Chen, Dawei ^a,c   Mei, Lin ^d  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

^c MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^d TSINGHUA UNIVERSITY   (China)

Author keywords

Copolymer nanoparticles; Cytotoxicity; Doxorubicin; Multi drug resistance; PH sensitive

Indexed keywords

AMINO ACIDS; BIOCOMPATIBILITY; CHEMOTHERAPY; CONTROLLED DRUG DELIVERY; CYTOTOXICITY; PARTICLE SIZE; PH SENSORS; POLYETHYLENE GLYCOLS; POLYETHYLENES; TARGETED DRUG DELIVERY; TITRATION; TUMORS;

ANTITUMOR DRUGS; COPOLYMER NANOPARTICLE; DOXORUBICIN; MULTIDRUG RESISTANCE; PH-SENSITIVE; POLY LACTIDE-CO-GLYCOLIDE; POLY(L-HISTIDINE); POLY-L-HISTIDINE; POLY-LACTIDE-CO-GLYCOLIDE; POLYLACTIDE-CO-GLYCOLIDE;

NANOPARTICLES;

DOXORUBICIN; MACROGOL; POLY(L HISTIDINE); POLYGLACTIN; SUCCINIC ACID; UNCLASSIFIED DRUG; ALPHA TOCOPHEROL; ANTINEOPLASTIC ANTIBIOTIC; DRUG CARRIER; HISTIDINE; NANOPARTICLE; POLYHISTIDINE; TOCOFERSOLAN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL VIABILITY; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR WEIGHT; PARTICLE SIZE; PH; POLYMERIZATION; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; CHEMISTRY; DRUG SCREENING; FEMALE;

ANTIBIOTICS, ANTINEOPLASTIC; DOXORUBICIN; DRUG CARRIERS; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HISTIDINE; HUMANS; HYDROGEN-ION CONCENTRATION; NANOPARTICLES; POLYGLACTIN 910; VITAMIN E;

EID: 84925011782     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2014.09.014     Document Type: Article

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