Cell-specific biotransformation of benzophenone-2 and bisphenol-s in zebrafish and human in vitro models used for toxicity and estrogenicity screening

Environmental Science and Technology

Volumn 49, Issue 6, 2015, Pages 3860-3868

  Le Fol, Vincent ^a,b   Aït Aïssa, Selim ^a   Cabaton, Nicolas ^b   Dolo, Laurence ^b   Grimaldi, Marina ^c   Balaguer, Patrick ^c   Perdu, Elisabeth ^b   Debrauwer, Laurent ^b   Brion, François ^a   Zalko, Daniel ^b  

^a INSTITUT NATIONAL DE L ENVIRONNEMENT INDUSTRIEL ET DES RISQUES INERIS   (France)

^b TOXALIM RESEARCH CENTRE IN FOOD TOXICOLOGY   (France)

^c UNIV MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCONVERSION; CELL CULTURE; CHEMICALS; CYTOLOGY; ENDOCRINE DISRUPTERS; ENDOCRINOLOGY; FISH; METABOLISM; MOBILE SECURITY; PHENOLS; TOXICITY;

CELLULAR CONTEXTS; CONJUGATED METABOLITES; ENDOCRINE DISRUPTING CHEMICALS; ESTROGENIC ACTIVITIES; ESTROGENIC CHEMICALS; METABOLIC CAPABILITIES; METABOLIC PATTERNS; PRIMARY HEPATOCYTES;

CELLS;

BENZOPHENONE 2; BENZOPHENONE DERIVATIVE; BISPHENOL S; PHENOL DERIVATIVE; UNCLASSIFIED DRUG; 2,2',4,4'-TETRAHYDROXYBENZOPHENONE; BIS(4-HYDROXYPHENYL)SULFONE; ESTROGEN; SULFONE;

BIOASSAY; BIOTRANSFORMATION; CYPRINID; CYTOLOGY; ENDOCRINE DISRUPTOR; ESTROGENIC COMPOUND; FILTER; TOXICITY;

ANIMAL CELL; ARTICLE; BIOASSAY; BIOTRANSFORMATION; CELL METABOLISM; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ELECTROSPRAY MASS SPECTROMETRY; ESTROGENICITY SCREENING; HUMAN; HUMAN CELL; HYDROLYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITE; NONHUMAN; SCREENING; ZEBRA FISH; ANIMAL; BOVINE; CELL LINE; DRUG EFFECTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER; LIVER CELL; METABOLISM;

DANIO RERIO;

ANIMALS; BENZOPHENONES; BIOTRANSFORMATION; CATTLE; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESTROGENS; HEPATOCYTES; HUMANS; LIVER; PHENOLS; SULFONES; ZEBRAFISH;

EID: 84925003526     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es505302c     Document Type: Article

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