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Volumn 5, Issue 11, 2014, Pages

Nuclear factor-kappaB sensitizes to benzyl isothiocyanate-induced antiproliferation in p53-deficient colorectal cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BENZYL ISOTHIOCYANATE; BETA CATENIN; CYCLIN D1; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P53; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELA; TUMOR SUPPRESSOR PROTEIN; CCND1 PROTEIN, HUMAN; CTNNB1 PROTEIN, HUMAN; ISOTHIOCYANIC ACID DERIVATIVE;

EID: 84924991492     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.495     Document Type: Article
Times cited : (30)

References (55)
  • 3
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of beta-catenin with the transcription factor LEF-1
    • Behrens J, von Kries JP, Kuhl M, Bruhn L, Wedlich D, Grosschedl R et al. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996; 382: 638-642.
    • (1996) Nature , vol.382 , pp. 638-642
    • Behrens, J.1    Von Kries, J.P.2    Kuhl, M.3    Bruhn, L.4    Wedlich, D.5    Grosschedl, R.6
  • 5
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O, McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999; 398: 422-426.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 6
    • 0030949419 scopus 로고    scopus 로고
    • Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells
    • Arber N, Doki Y, Han EK, Sgambato A, Zhou P, Kim NH et al. Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells. Cancer Res 1997; 57: 1569-1574.
    • (1997) Cancer Res , vol.57 , pp. 1569-1574
    • Arber, N.1    Doki, Y.2    Han, E.K.3    Sgambato, A.4    Zhou, P.5    Kim, N.H.6
  • 7
    • 4344689970 scopus 로고    scopus 로고
    • Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice
    • Hulit J, Wang C, Li Z, Albanese C, Rao M, Di Vizio D et al. Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice. Mol Cell Biol 2004; 24: 7598-7611.
    • (2004) Mol Cell Biol , vol.24 , pp. 7598-7611
    • Hulit, J.1    Wang, C.2    Li, Z.3    Albanese, C.4    Rao, M.5    Di Vizio, D.6
  • 9
    • 0032588170 scopus 로고    scopus 로고
    • NF-kappaB function in growth control: Regulation of cyclin D1 expression and G0/G1-to-S-phase transition
    • Hinz M, Krappmann D, Eichten A, Heder A, Scheidereit C, Strauss M. NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition. Mol Cell Biol 1999; 19: 2690-2698.
    • (1999) Mol Cell Biol , vol.19 , pp. 2690-2698
    • Hinz, M.1    Krappmann, D.2    Eichten, A.3    Heder, A.4    Scheidereit, C.5    Strauss, M.6
  • 10
    • 0032588186 scopus 로고    scopus 로고
    • NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1
    • Guttridge DC, Albanese C, Reuther JY, Pestell RG, Baldwin AJ. NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol Cell Biol 1999; 19: 5785-5799.
    • (1999) Mol Cell Biol , vol.19 , pp. 5785-5799
    • Guttridge, D.C.1    Albanese, C.2    Reuther, J.Y.3    Pestell, R.G.4    Baldwin, A.J.5
  • 11
    • 0024759789 scopus 로고
    • A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by i kappaB
    • Baeuerle PA, Baltimore D. A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB. Genes Dev 1989; 3: 1689-1698.
    • (1989) Genes Dev , vol.3 , pp. 1689-1698
    • Baeuerle, P.A.1    Baltimore, D.2
  • 12
    • 0028986075 scopus 로고
    • Control of i kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation
    • Brown K, Gerstberger S, Carlson L, Franzoso G, Siebenlist U. Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. Science 1995; 267: 1485-1488.
    • (1995) Science , vol.267 , pp. 1485-1488
    • Brown, K.1    Gerstberger, S.2    Carlson, L.3    Franzoso, G.4    Siebenlist, U.5
  • 13
    • 0141703513 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway
    • Sakurai H, Suzuki S, Kawasaki N, Nakano H, Okazaki T, Chino A et al. Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway. J Biol Chem 2003; 278: 36916-36923.
    • (2003) J Biol Chem , vol.278 , pp. 36916-36923
    • Sakurai, H.1    Suzuki, S.2    Kawasaki, N.3    Nakano, H.4    Okazaki, T.5    Chino, A.6
  • 14
    • 0036584632 scopus 로고    scopus 로고
    • RelA suppresses the Wnt/beta-catenin pathway without exerting trans-acting transcriptional ability
    • Masui O, Ueda Y, Tsumura A, Koyanagi M, Hijikata M, Shimotohno K. RelA suppresses the Wnt/beta-catenin pathway without exerting trans-acting transcriptional ability. Int J Mol Med 2002; 9: 489-493.
    • (2002) Int J Mol Med , vol.9 , pp. 489-493
    • Masui, O.1    Ueda, Y.2    Tsumura, A.3    Koyanagi, M.4    Hijikata, M.5    Shimotohno, K.6
  • 15
    • 0036781671 scopus 로고    scopus 로고
    • β-catenin interacts with and inhibits NF-κB in human colon and breast cancer
    • Deng J, Miller SA, Wang H, Xia W, Wen Y, Zhou BP et al. β-catenin interacts with and inhibits NF-κB in human colon and breast cancer. Cancer Cell 2002; 2: 323-334.
    • (2002) Cancer Cell , vol.2 , pp. 323-334
    • Deng, J.1    Miller, S.A.2    Wang, H.3    Xia, W.4    Wen, Y.5    Zhou, B.P.6
  • 16
    • 84858706841 scopus 로고    scopus 로고
    • Cross-regulation between Wnt and NF-kappaB signaling pathways
    • Du Q, Geller DA. Cross-regulation between Wnt and NF-kappaB signaling pathways. For Immunopathol Dis Therap 2010; 1: 155-181.
    • (2010) For Immunopathol Dis Therap , vol.1 , pp. 155-181
    • Du, Q.1    Geller, D.A.2
  • 17
    • 78649699068 scopus 로고    scopus 로고
    • NF-kappaB p65 represses beta-catenin-activated transcription of cyclin D1
    • Hwang I, Choi YS, Jeon MY, Jeong S. NF-kappaB p65 represses beta-catenin-activated transcription of cyclin D1. Biochem Biophys Res Commun 2010; 403: 79-84.
    • (2010) Biochem Biophys Res Commun , vol.403 , pp. 79-84
    • Hwang, I.1    Choi, Y.S.2    Jeon, M.Y.3    Jeong, S.4
  • 18
    • 77249089780 scopus 로고    scopus 로고
    • Electrophiles in foods: The current status of isothiocyanates and their chemical biology
    • Nakamura Y, Miyoshi N. Electrophiles in foods: the current status of isothiocyanates and their chemical biology. Biosci Biotechnol Biochem 2010; 74: 242-255.
    • (2010) Biosci Biotechnol Biochem , vol.74 , pp. 242-255
    • Nakamura, Y.1    Miyoshi, N.2
  • 19
    • 84875576152 scopus 로고    scopus 로고
    • Cruciferous vegetables intake and the risk of colorectal cancer: A meta-analysis of observational studies
    • Wu QJ, Yang Y, Vogtmann E, Wang J, Han LH, Li HL et al. Cruciferous vegetables intake and the risk of colorectal cancer: a meta-analysis of observational studies. Ann Oncol 2013; 24: 1079-1087.
    • (2013) Ann Oncol , vol.24 , pp. 1079-1087
    • Wu, Q.J.1    Yang, Y.2    Vogtmann, E.3    Wang, J.4    Han, L.H.5    Li, H.L.6
  • 21
    • 1542615077 scopus 로고    scopus 로고
    • A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: Involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation
    • Miyoshi N, Uchida K, Osawa T, Nakamura Y. A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation. Cancer Res 2004; 64: 2134-2142.
    • (2004) Cancer Res , vol.64 , pp. 2134-2142
    • Miyoshi, N.1    Uchida, K.2    Osawa, T.3    Nakamura, Y.4
  • 22
    • 0035881570 scopus 로고    scopus 로고
    • Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines
    • Bonnesen C, Eggleston IM, Hayes JD. Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines. Cancer Res 2001; 61: 6120-6130.
    • (2001) Cancer Res , vol.61 , pp. 6120-6130
    • Bonnesen, C.1    Eggleston, I.M.2    Hayes, J.D.3
  • 23
    • 0038059372 scopus 로고    scopus 로고
    • Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide-and interferon-gamma-induced IkappaB degradation in RAW264.7 macrophages
    • Murakami A, Matsumoto K, Koshimizu K, Ohigashi H. Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide-and interferon-gamma-induced IkappaB degradation in RAW264.7 macrophages. Cancer Lett 2003; 195: 17-25.
    • (2003) Cancer Lett , vol.195 , pp. 17-25
    • Murakami, A.1    Matsumoto, K.2    Koshimizu, K.3    Ohigashi, H.4
  • 24
    • 83555165930 scopus 로고    scopus 로고
    • Benzyl isothiocyanate inhibits basal and hepatocyte growth factor-stimulated migration of breast cancer cells
    • Kim EJ, Eom SJ, Hong JE, Lee JY, Choi MS, Park JH. Benzyl isothiocyanate inhibits basal and hepatocyte growth factor-stimulated migration of breast cancer cells. Mol Cell Biochem 2012; 359: 431-440.
    • (2012) Mol Cell Biochem , vol.359 , pp. 431-440
    • Kim, E.J.1    Eom, S.J.2    Hong, J.E.3    Lee, J.Y.4    Choi, M.S.5    Park, J.H.6
  • 25
    • 33745809820 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells
    • Yang J, Zhang W, Evans PM, Chen X, He X, Liu C. Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells. J Biol Chem 2006; 281: 17751-17757.
    • (2006) J Biol Chem , vol.281 , pp. 17751-17757
    • Yang, J.1    Zhang, W.2    Evans, P.M.3    Chen, X.4    He, X.5    Liu, C.6
  • 26
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997; 275: 1787-1790.
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3    Barker, N.4    Clevers, H.5    Vogelstein, B.6
  • 27
    • 21744444276 scopus 로고    scopus 로고
    • Nucleolar sequestration of RelA (p65) regulates NF-kappaB-driven transcription and apoptosis
    • Stark LA, Dunlop MG. Nucleolar sequestration of RelA (p65) regulates NF-kappaB-driven transcription and apoptosis. Mol Cell Biol 2005; 25: 5985-6004.
    • (2005) Mol Cell Biol , vol.25 , pp. 5985-6004
    • Stark, L.A.1    Dunlop, M.G.2
  • 28
    • 52049113028 scopus 로고    scopus 로고
    • Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis
    • Mi L, Xiao Z, Hood BL, Dakshanamurthy S, Wang X, Govind S et al. Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis. J Biol Chem 2008; 283: 22136-22146.
    • (2008) J Biol Chem , vol.283 , pp. 22136-22146
    • Mi, L.1    Xiao, Z.2    Hood, B.L.3    Dakshanamurthy, S.4    Wang, X.5    Govind, S.6
  • 29
    • 0035094701 scopus 로고    scopus 로고
    • Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates
    • Zhang Y. Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates. Carcinogenesis 2001; 22: 425-431.
    • (2001) Carcinogenesis , vol.22 , pp. 425-431
    • Zhang, Y.1
  • 30
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006; 441: 431-436.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 31
    • 77449136821 scopus 로고    scopus 로고
    • Identification of a novel pro-apopotic function of NF-kappaB in the DNA damage response
    • Karl S, Pritschow Y, Volcic M, Hacker S, Baumann B, Wiesmuller L et al. Identification of a novel pro-apopotic function of NF-kappaB in the DNA damage response. J Cell Mol Med 2009; 13: 4239-4256.
    • (2009) J Cell Mol Med , vol.13 , pp. 4239-4256
    • Karl, S.1    Pritschow, Y.2    Volcic, M.3    Hacker, S.4    Baumann, B.5    Wiesmuller, L.6
  • 32
    • 80054789761 scopus 로고    scopus 로고
    • Control of the senescence-associated secretory phenotype by NF-kappaB promotes senescence and enhances chemosensitivity
    • Chien Y, Scuoppo C, Wang X, Fang X, Balgley B, Bolden JE et al. Control of the senescence-associated secretory phenotype by NF-kappaB promotes senescence and enhances chemosensitivity. Genes Dev 2011; 25: 2125-2136.
    • (2011) Genes Dev , vol.25 , pp. 2125-2136
    • Chien, Y.1    Scuoppo, C.2    Wang, X.3    Fang, X.4    Balgley, B.5    Bolden, J.E.6
  • 33
    • 80054784360 scopus 로고    scopus 로고
    • Opposing roles of NF-kappaB in anti-cancer treatment outcome unveiled by cross-species investigations
    • Jing H, Kase J, Dorr JR, Milanovic M, Lenze D, Grau M et al. Opposing roles of NF-kappaB in anti-cancer treatment outcome unveiled by cross-species investigations. Genes Dev 2011; 25: 2137-2146.
    • (2011) Genes Dev , vol.25 , pp. 2137-2146
    • Jing, H.1    Kase, J.2    Dorr, J.R.3    Milanovic, M.4    Lenze, D.5    Grau, M.6
  • 34
    • 84858337114 scopus 로고    scopus 로고
    • Identification of a novel pro-apoptotic role of NF-kappaB in the regulation of TRAIL-and CD95-mediated apoptosis of glioblastoma cells
    • Jennewein C, Karl S, Baumann B, Micheau O, Debatin KM, Fulda S. Identification of a novel pro-apoptotic role of NF-kappaB in the regulation of TRAIL-and CD95-mediated apoptosis of glioblastoma cells. Oncogene 2012; 31: 1468-1474.
    • (2012) Oncogene , vol.31 , pp. 1468-1474
    • Jennewein, C.1    Karl, S.2    Baumann, B.3    Micheau, O.4    Debatin, K.M.5    Fulda, S.6
  • 35
    • 81255192180 scopus 로고    scopus 로고
    • The two faces of NF-kappaB signaling in cancer development and therapy
    • Klein U, Ghosh S. The two faces of NF-kappaB signaling in cancer development and therapy. Cancer Cell 2011; 20: 556-558.
    • (2011) Cancer Cell , vol.20 , pp. 556-558
    • Klein, U.1    Ghosh, S.2
  • 36
    • 0027979264 scopus 로고
    • Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors
    • La Rosa FA, Pierce JW, Sonenshein GE. Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors. Mol Cell Biol 1994; 14: 1039-1044.
    • (1994) Mol Cell Biol , vol.14 , pp. 1039-1044
    • La Rosa, F.A.1    Pierce, J.W.2    Sonenshein, G.E.3
  • 38
    • 79953758074 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling enhances cyclooxygenase-2 (COX2) transcriptional activity in gastric cancer cells
    • Nunez F, Bravo S, Cruzat F, Montecino M, De Ferrari GV. Wnt/beta-catenin signaling enhances cyclooxygenase-2 (COX2) transcriptional activity in gastric cancer cells. PLoS One 2011; 6: e18562.
    • (2011) PLoS One , vol.6 , pp. e18562
    • Nunez, F.1    Bravo, S.2    Cruzat, F.3    Montecino, M.4    De Ferrari, G.V.5
  • 39
    • 0028069896 scopus 로고
    • The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells
    • Inoue H, Nanayama T, Hara S, Yokoyama C, Tanabe T. The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells. Febs Lett 1994; 350: 51-54.
    • (1994) Febs Lett , vol.350 , pp. 51-54
    • Inoue, H.1    Nanayama, T.2    Hara, S.3    Yokoyama, C.4    Tanabe, T.5
  • 41
    • 0037388638 scopus 로고    scopus 로고
    • Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells
    • Verma UN, Surabhi RM, Schmaltieg A, Becerra C, Gaynor RB. Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells. Clin Cancer Res 2003; 9: 1291-1300.
    • (2003) Clin Cancer Res , vol.9 , pp. 1291-1300
    • Verma, U.N.1    Surabhi, R.M.2    Schmaltieg, A.3    Becerra, C.4    Gaynor, R.B.5
  • 42
    • 0035252741 scopus 로고    scopus 로고
    • The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate beta-catenin/TCF-4 signaling
    • Dihlmann S, Siermann A, von Knebel DM. The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate beta-catenin/TCF-4 signaling. Oncogene 2001; 20: 645-653.
    • (2001) Oncogene , vol.20 , pp. 645-653
    • Dihlmann, S.1    Siermann, A.2    Von Knebel, D.M.3
  • 43
    • 78649699068 scopus 로고    scopus 로고
    • NF-κB p65 represses β-catenin-activated transcription of cyclin D1
    • Hwang I, Choi YS, Jeon M, Jeong S. NF-κB p65 represses β-catenin-activated transcription of cyclin D1. Biochem Bioph Res Co 2010; 403: 79-84.
    • (2010) Biochem Bioph Res Co , vol.403 , pp. 79-84
    • Hwang, I.1    Choi, Y.S.2    Jeon, M.3    Jeong, S.4
  • 44
    • 33845353379 scopus 로고    scopus 로고
    • The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in the Singapore Chinese Health Study
    • Probst-Hensch NM, Sun C, Berg DVD, Ceschi M, Koh W, Yu MC. The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in the Singapore Chinese Health Study. Carcinogenesis 2006; 27: 2475-2482.
    • (2006) Carcinogenesis , vol.27 , pp. 2475-2482
    • Probst-Hensch, N.M.1    Sun, C.2    Berg, D.V.D.3    Ceschi, M.4    Koh, W.5    Yu, M.C.6
  • 45
    • 42949121566 scopus 로고    scopus 로고
    • Chemoprevention of familial adenomatous polyposis in Apc(Min/+) mice by phenethyl isothiocyanate (PEITC)
    • Khor TO, Cheung WK, Prawan A, Reddy BS, Kong AN. Chemoprevention of familial adenomatous polyposis in Apc(Min/+) mice by phenethyl isothiocyanate (PEITC). Mol Carcinog 2008; 47: 321-325.
    • (2008) Mol Carcinog , vol.47 , pp. 321-325
    • Khor, T.O.1    Cheung, W.K.2    Prawan, A.3    Reddy, B.S.4    Kong, A.N.5
  • 47
    • 62549161375 scopus 로고    scopus 로고
    • Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification
    • Kawauchi K, Araki K, Tobiume K, Tanaka N. Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification. Proc Natl Acad Sci USA 2009; 106: 3431-3436.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 3431-3436
    • Kawauchi, K.1    Araki, K.2    Tobiume, K.3    Tanaka, N.4
  • 48
    • 33845714925 scopus 로고    scopus 로고
    • Selective cytotoxicity of benzyl isothiocyanate in the proliferating fibroblastoid cells
    • Miyoshi N, Uchida K, Osawa T, Nakamura Y. Selective cytotoxicity of benzyl isothiocyanate in the proliferating fibroblastoid cells. Int J Cancer 2007; 120: 484-492.
    • (2007) Int J Cancer , vol.120 , pp. 484-492
    • Miyoshi, N.1    Uchida, K.2    Osawa, T.3    Nakamura, Y.4
  • 49
    • 0031892793 scopus 로고    scopus 로고
    • Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates
    • Chen YR, Wang W, Kong AN, Tan TH. Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates. J Biol Chem 1998; 273: 1769-1775.
    • (1998) J Biol Chem , vol.273 , pp. 1769-1775
    • Chen, Y.R.1    Wang, W.2    Kong, A.N.3    Tan, T.H.4
  • 50
    • 0037040918 scopus 로고    scopus 로고
    • Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis
    • Nakamura Y, Kawakami M, Yoshihiro A, Miyoshi N, Ohigashi H, Kawai K et al. Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis. J Biol Chem 2002; 277: 8492-8499.
    • (2002) J Biol Chem , vol.277 , pp. 8492-8499
    • Nakamura, Y.1    Kawakami, M.2    Yoshihiro, A.3    Miyoshi, N.4    Ohigashi, H.5    Kawai, K.6
  • 51
    • 77950135036 scopus 로고    scopus 로고
    • Immunochemical detection of food-derived isothiocyanate as a lysine conjugate
    • Nakamura T, Kitamoto N, Osawa T, Kato Y. Immunochemical detection of food-derived isothiocyanate as a lysine conjugate. Biosci Biotechnol Biochem 2010; 74: 536-540.
    • (2010) Biosci Biotechnol Biochem , vol.74 , pp. 536-540
    • Nakamura, T.1    Kitamoto, N.2    Osawa, T.3    Kato, Y.4
  • 52
    • 80053154634 scopus 로고    scopus 로고
    • Proteins as binding targets of isothiocyanates in cancer prevention
    • Mi L, Di Pasqua AJ, Chung FL. Proteins as binding targets of isothiocyanates in cancer prevention. Carcinogenesis 2011; 32: 1405-1413.
    • (2011) Carcinogenesis , vol.32 , pp. 1405-1413
    • Mi, L.1    Di Pasqua, A.J.2    Chung, F.L.3
  • 53
    • 0036135910 scopus 로고    scopus 로고
    • Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: Pharmacokinetics of broccoli sprout isothiocyanates in humans
    • Ye L, Dinkova-Kostova AT, Wade KL, Zhang Y, Shapiro TA, Talalay P. Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans. Clin Chim Acta 2002; 316: 43-53.
    • (2002) Clin Chim Acta , vol.316 , pp. 43-53
    • Ye, L.1    Dinkova-Kostova, A.T.2    Wade, K.L.3    Zhang, Y.4    Shapiro, T.A.5    Talalay, P.6
  • 54
    • 84883557031 scopus 로고    scopus 로고
    • Determination of benzyl isothiocyanate metabolites in human plasma and urine by LC-ESI-MS/MS after ingestion of nasturtium (Tropaeolum majus L.)
    • Platz S, Kuhn C, Schiess S, Schreiner M, Mewis I, Kemper M et al. Determination of benzyl isothiocyanate metabolites in human plasma and urine by LC-ESI-MS/MS after ingestion of nasturtium (Tropaeolum majus L.). Anal Bioanal Chem 2013; 405: 7427-7436.
    • (2013) Anal Bioanal Chem , vol.405 , pp. 7427-7436
    • Platz, S.1    Kuhn, C.2    Schiess, S.3    Schreiner, M.4    Mewis, I.5    Kemper, M.6


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