Investigating the airborne transmission pathway - different approaches with the same objectives

Indoor Air

Volumn 25, Issue 2, 2015, Pages 119-124

  Tang, Julian W ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AIRBORNE TRANSMISSION;

BACTERIAL DNA; BACTERIAL RNA; VIRUS DNA; VIRUS RNA;

AIR; COMMUNICABLE DISEASE; EXPOSURE; HUMAN; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MOLECULAR MEDICINE; PROCEDURES; RESPIRATORY SYSTEM; TRANSMISSION;

AIR MICROBIOLOGY; AIR MOVEMENTS; COMMUNICABLE DISEASES; DNA, BACTERIAL; DNA, VIRAL; HUMANS; INHALATION EXPOSURE; MICROBIOLOGICAL TECHNIQUES; MOLECULAR MEDICINE; RESPIRATORY SYSTEM; RNA, BACTERIAL; RNA, VIRAL;

EID: 84924968983     PISSN: 09056947     EISSN: 16000668     Source Type: Journal    
DOI: 10.1111/ina.12175     Document Type: Editorial

References (72)

1. Beggs, C.B., Kerr, K.G., Noakes, C.J., Hathway, E.A. and Sleigh, P.A. (2008) The ventilation of multiple-bed hospital wards: review and analysis, Am. J. Infect. Control, 36, 250-259.
2. Blachere, F.M., Lindsley, W.G., Slaven, J.E., Green, B.J., Anderson, S.E., Chen, B.T. and Beezhold, D.H. (2007) Bioaerosol sampling for the detection of aerosolized influenza virus, Influenza Other Respir, Viruses, 1, 113-120.
3. Blachere, F.M., Lindsley, W.G., Pearce, T.A., Anderson, S.E., Fisher, M., Khakoo, R., Meade, B.J., Lander, O., Davis, S., Thewlis, R.E., Celik, I., Chen, B.T. and Beezhold, D.H. (2009) Measurement of airborne influenza virus in a hospital emergency department, Clin. Infect. Dis., 15, 438-440.
4. Blachere, F.M., Cao, G., Lindsley, W.G., Noti, J.D. and Beezhold, D.H. (2011) Enhanced detection of infectious airborne influenza virus, J. Virol. Methods, 176, 120-124.
5. BMJ (2014) Tamiflu campaign. Br. Med. J., http://www.bmj.com/tamiflu. Accessed 27 November 2014.
6. Booth, T.F., Kournikakis, B., Bastien, N., Ho, J., Kobasa, D., Stadnyk, L., Li, Y., Spence, M., Paton, S., Henry, B., Mederski, B., White, D., Low, D.E., McGeer, A., Simor, A., Vearncombe, M., Downey, J., Jamieson, F.B., Tang, P., Plummer, F. (2005) Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units, J. Infect. Dis., 191, 1472-1477.
7. Borojeni, A.A., Noga, M.L., Vehring, R. and Finlay, W.H. (2014) Measurements of total aerosol deposition in intrathoracic conducting airway replicas of children, J. Aerosol Sci., 73, 39-47.
8. Cao, G., Noti, J.D., Blachere, F.M., Lindsley, W.G. and Beezhold, D.H. (2011) Development of an improved methodology to detect infectious airborne influenza virus using the NIOSH bioaerosol sampler, J. Environ. Monit., 13, 3321-3328.
9. CDC (2014) Ebola Outbreak in West Africa. Centers for Disease Control and Prevention. http://www.cdc.gov/vhf/ebola/outbreaks/2014-west-africa/index.html. Accessed 27 November 2014.
10. Chan, M.C., Lee, N., Ngai, K.L., Wong, B.C., Lee, M.K., Choi, K.W., Lai, R.W. and Chan, P.K. (2013) A "pre-seasonal" hospital outbreak of influenza pneumonia caused by the drift variant A/Victoria/361/2011-like H3N2 viruses, Hong Kong, 2011, J. Clin. Virol., 56, 219-225.
11. Chao, C.Y.H., Wan, M.P., Morawska, L., Johnson, G.R., Ristovski, Z.D., Hargreaves, M., Mengersen, K., Corbett, S., Li, Y., Xie, X. and Katoshevski, D. (2009) Characterization of expiration air jets and droplet size distributions immediately at the mouth opening, J. Aerosol Sci., 40, 122-133.
12. Choi, J.I. and Edwards, J.R. (2012) Large-eddy simulation of human-induced contaminant transport in room compartments, Indoor Air, 22, 77-87.
13. Chu, C.M., Poon, L.L., Cheng, V.C., Chan, K.S., Hung, I.F., Wong, M.M., Chan, K.H., Leung, W.S., Tang, B.S., Chan, V.L., Ng, W.L., Sim, T.C., Ng, P.W., Law, K.I., Tse, D.M., Peiris, J.S. and Yuen, K.Y. (2004) Initial viral load and the outcomes of SARS, CMAJ, 171, 1349-1352.
14. CIDRAP (2014a) Commentary: Protecting Health Workers from Airborne MERS-CoV-Learning from SARS. Minneapolis, MN, USA, Center for Infectious Disease Research and Policy, Academic Health Center, University of Minnesota. http://www.cidrap.umn.edu/news-perspective/2014/05/commentary-protecting-health-workers-airborne-mers-cov-learning-sars. Accessed 27 November 2014.
15. CIDRAP (2014b) Commentary: Health Workers Need Optimal Respiratory Protection for Ebola. Minneapolis, MN, USA, Center for Infectious Disease Research and Policy, Academic Health Center, University of Minnesota. http://www.cdc.gov/vhf/ebola/outbreaks/2014-west-africa/index.html. Accessed 27 November 2014.
16. Clark, R.P. and de Calcina-Goff, M.L. (2009) Some aspects of the airborne transmission of infection, J. R. Soc. Interface, 6(Suppl 6), S767-S782.
17. Craven, B.A. and Settles, G.S. (2006) A computational and experimental investigation of the human thermal plume, J. Fluids Eng., 128, 1251-1258.
18. Edwards, D.A., Man, J.C., Brand, P., Katstra, J.P., Sommerei, K., Stone, H.A., Nardell, E. and Scheuch, G. (2004) Inhaling to mitigate exhaled bioaerosols, Proc. Natl Acad. Sci. USA, 101, 17383-17388.
19. Fabian, P., McDevitt, J.J., DeHaan, W.H., Fung, R.O., Cowling, B.J., Chan, K.H., Leung, G.M. and Milton, D.K. (2008) Influenza virus in human exhaled breath: an observational study, PLoS ONE, 3, e2691.
20. Fabian, P., McDevitt, J.J., Houseman, E.A. and Milton, D.K. (2009) Airborne influenza virus detection with four aerosol samplers using molecular and infectivity assays: considerations for a new infectious virus aerosol sampler, Indoor Air, 19, 433-441.
21. Fennelly, K.P., Martyny, J.W., Fulton, K.E., Orme, I.M., Cave, D.M. and Heifets, L.B. (2004) Cough-generated aerosols of Mycobacterium tuberculosis: a new method to study infectiousness, Am. J. Respir. Crit. Care Med., 169, 604-609.
22. Gangneux, J.P., Robert-Gangneux, F., Gicquel, G., Tanquerel, J.J., Chevrier, S., Poisson, M., Aupée, M. and Guiguen, C. (2006) Bacterial and fungal counts in hospital air: comparative yields for 4 sieve impactor air samplers with 2 culture media, Infect. Control Hosp. Epidemiol., 27, 1405-1408.
23. Gupta, J.K., Lin, C.H. and Chen, Q. (2011) Transport of expiratory droplets in an aircraft cabin, Indoor Air, 21, 3-11.
24. Hatagishi, E., Okamoto, M., Ohmiya, S., Yano, H., Hori, T., Saito, W., Miki, H., Suzuki, Y., Saito, R., Yamamoto, T., Shoji, M., Morisaki, Y., Sakata, S. and Nishimura, H. (2014) Establishment and clinical applications of a portable system for capturing influenza viruses released through coughing, PLoS ONE, 9, e103560.
25. Hui, D.S., Hall, S.D., Chan, M.T., Chow, B.K., Tsou, J.Y., Joynt, G.M., Sullivan, C.E. and Sung, J.J. (2006) Noninvasive positive-pressure ventilation: an experimental model to assess air and particle dispersion, Chest, 130, 730-740.
26. Huynh, K.N., Oliver, B.G., Stelzer, S., Rawlinson, W.D. and Tovey, E.R. (2008) A new method for sampling and detection of exhaled respiratory virus aerosols, Clin. Infect. Dis., 46, 93-95.
27. Kamigaki, T., Seino, J., Tohma, K., Nukiwa-Soma, N., Otani, K. and Oshitani, H. (2014) Investigation of an Influenza A (H3N2) outbreak in evacuation centres following the Great East Japan earthquake, 2011, BMC Public Health, 14, 34.
28. Knibbs, L.D., Johnson, G.R., Kidd, T.J., Cheney, J., Grimwood, K., Kattenbelt, J.A., O'Rourke, P.K., Ramsay, K.A., Sly, P.D., Wainwright, C.E., Wood, M.E., Morawska, L. and Bell, S.C. (2014) Viability of Pseudomonas aeruginosa in cough aerosols generated by persons with cystic fibrosis, Thorax, 69, 740-745.
29. Koehler, K.A., Anthony, T.R., Van Dyke, M. and Volckens, J. (2012) Solid versus liquid particle sampling efficiency of three personal aerosol samplers when facing the wind, Ann. Occup. Hyg., 56, 194-206.
30. Lee, C.K., Lee, H.K., Loh, T.P., Lai, F.Y., Tambyah, P.A., Chiu, L., Koay, E.S. and Tang, J.W. (2011) Comparison of pandemic (H1N1) 2009 and seasonal influenza viral loads, Singapore, Emerg. Infect. Dis., 17, 287-291.
31. Licina, D., Pantelic, J., Melikov, A., Sekhar, C. and Tham, K.W. (2014) Experimental investigation of the human convective boundary layer in a quiescent indoor environment, Build. Environ., 75, 79-91.
32. Licina, D., Melikov, A., Sekhar, C. and Tham, K.W. (2015) Human convective boundary layer and its interaction with room ventilation flow, Indoor Air, 25, 21-35.
33. Lindsley, W.G., Blachere, F.M., Davis, K.A., Pearce, T.A., Fisher, M.A., Khakoo, R., Davis, S.M., Rogers, M.E., Thewlis, R.E., Posada, J.A., Redrow, J.B., Celik, I.B., Chen, B.T. and Beezhold, D.H. (2010a) Distribution of airborne influenza virus and respiratory syncytial virus in an urgent care medical clinic, Clin. Infect. Dis., 50, 693-698.
34. Lindsley, W.G., Blachere, F.M., Thewlis, R.E., Vishnu, A., Davis, K.A., Cao, G., Palmer, J.E., Clark, K.E., Fisher, M.A., Khakoo, R. and Beezhold, D.H. (2010b) Measurements of airborne influenza virus in aerosol particles from human coughs, PLoS ONE, 5, e15100.
35. Lindsley, W.G., Pearce, T.A., Hudnall, J.B., Davis, K.A., Davis, S.M., Fisher, M.A., Khakoo, R., Palmer, J.E., Clark, K.E., Celik, I., Coffey, C.C., Blachere, F.M. and Beezhold, D.H. (2012) Quantity and size distribution of cough-generated aerosol particles produced by influenza patients during and after illness, J. Occup. Environ. Hyg., 9, 443-449.
36. Matrosovich, M.N., Matrosovich, T.Y., Gray, T., Roberts, N.A. and Klenk, H.D. (2004) Human and avian influenza viruses target different cell types in cultures of human airway epithelium, Proc. Natl Acad. Sci. USA, 101, 4620-4624.
37. McDevitt, J.J., Koutrakis, P., Ferguson, S.T., Wolfson, J.M., Fabian, M.P., Martins, M., Pantelic, J. and Milton, D.K. (2013) Development and performance evaluation of an exhaled-breath bioaerosol collector for influenza virus, Aerosol Sci. Technol., 47, 444-451.
38. Memish, Z.A., Al-Tawfiq, J.A., Makhdoom, H.Q., Assiri, A., Alhakeem, R.F., Albarrak, A., Alsubaie, S., Al-Rabeeah, A.A., Hajomar, W.H., Hussain, R., Kheyami, A.M., Almutairi, A., Azhar, E.I., Drosten, C., Watson, S.J., Kellam, P., Cotton, M. and Zumla, A. (2014) Respiratory tract samples, viral load, and genome fraction yield in patients with Middle East respiratory syndrome, J. Infect. Dis., 210, 1590-1594.
39. Milton, D.K., Fabian, M.P., Cowling, B.J., Grantham, M.L. and McDevitt, J.J. (2013) Influenza virus aerosols in human exhaled breath: particle size, culturability, and effect of surgical masks, PLoS Pathog., 9, e1003205.
40. Morawska, L., Johnson, G.R., Ristovski, Z., Hargreaves, M., Mengersen, K., Chao, C.Y.H., Li, Y. and Katoshevski, D. (2009) Size distribution and sites of origins of droplets expelled from the human respiratory tract during expiratory activities, J. Aerosol Sci., 40, 256-269.
41. Murakami, S. (2004) Analysis and design of micro-climate around the human body with respiration by CFD, Indoor Air, 14, 144-156.
42. Nishimura, H., Sakata, S. and Kaga, A. (2013) A new methodology for studying dynamics of aerosol particles in sneeze and cough using a digital high-vision, high-speed video system and vector analyses, PLoS ONE, 8, e80244.
43. Pantelic, J., Sze-To, G.N., Tham, K.W., Chao, C.Y. and Khoo, Y.C. (2009) Personalized ventilation as a control measure for airborne transmissible disease spread, J. R. Soc. Interface, 6(Suppl 6), S715-S726.
44. van Riel, D., Munster, V.J., de Wit, E., Rimmelzwaan, G.F., Fouchier, R.A., Osterhaus, A.D. and Kuiken, T. (2006) H5N1 Virus attachment to lower respiratory tract, Science, 21, 399.
45. Ruzycki, C.A., Golshahi, L., Vehring, R. and Finlay, W.H. (2014) Comparison of in vitro deposition of pharmaceutical aerosols in an idealized child throat with in vivo deposition in the upper respiratory tract of children, Pharm. Res., 31, 1525-1535.
46. Settles, G.S. (2001) Schlieren and Shadowgraph Techniques, London, Springer.
47. Shinya, K., Ebina, M., Yamada, S., Ono, M., Kasai, N. and Kawaoka, Y. (2006) Avian flu: influenza virus receptors in the human airway, Nature, 440, 435-436.
48. Silva, M.L., Perrier, L., Späth, H.M., Grog, I., Mosnier, A., Havet, N., Cohen, J.M. and IBGP team (2014) Economic burden of seasonal influenza B in France during winter 2010-2011, BMC Public Health, 14, 56.
49. Sleeth, D.K. and Vincent, J.H. (2012) Performance study of personal inhalable aerosol samplers at ultra-low wind speeds, Ann. Occup. Hyg., 56, 207-220.
50. Stelzer-Braid, S., Oliver, B.G., Blazey, A.J., Argent, E., Newsome, T.P., Rawlinson, W.D. and Tovey, E.R. (2009) Exhalation of respiratory viruses by breathing, coughing, and talking, J. Med. Virol., 81, 1674-1679.
51. Suzuki, K., Yoshikawa, T., Tomitaka, A., Matsunaga, K. and Asano, Y. (2004) Detection of aerosolized varicella-zoster virus DNA in patients with localized herpes zoster, J. Infect. Dis., 189, 1009-1012.
52. Tang, J.W. and Settles, G.S. (2008) Images in clinical medicine. Coughing and aerosols, N. Engl. J. Med., 359, e19.
53. Tang, J.W., Liebner, T.J., Craven, B.A. and Settles, G.S. (2009) A schlieren optical study of the human cough with and without wearing masks for aerosol infection control, J. R. Soc. Interface, 6(Suppl 6), S727-S736.
54. Tang, J.W., Noakes, C.J., Nielsen, P.V., Eames, I., Nicolle, A., Li, Y. and Settles, G.S. (2011) Observing and quantifying airflows in the infection control of aerosol- and airborne-transmitted diseases: an overview of approaches, J. Hosp. Infect., 77, 213-222.
55. Tang, J.W., Nicolle, A.D., Klettner, C.A., Pantelic, J., Wang, L., Suhaimi, A.B., Tan, A.Y., Ong, G.W., Su, R., Sekhar, C., Cheong, D.K. and Tham, K.W. (2013) Airflow dynamics of human jets: sneezing and breathing - potential sources of infectious aerosols, PLoS ONE, 8, e59970.
56. Tang, J.W., Gao, C.X., Cowling, B.J., Koh, G.C., Chu, D., Heilbronn, C., Lloyd, B., Pantelic, J., Nicolle, A.D., Klettner, C.A., Peiris, J.S., Sekhar, C., Cheong, D.K., Tham, K.W., Koay, E.S., Tsui, W., Kwong, A., Chan, K. and Li, Y. (2014) Absence of detectable influenza RNA transmitted via aerosol during various human respiratory activities-experiments from Singapore and Hong Kong, PLoS ONE, 9, e107338.
57. To, K.K., Chan, K.H., Li, I.W., Tsang, T.Y., Tse, H., Chan, J.F., Hung, I.F., Lai, S.T., Leung, C.W., Kwan, Y.W., Lau, Y.L., Ng, T.K., Cheng, V.C., Peiris, J.S. and Yuen, K.Y. (2010) Viral load in patients infected with pandemic H1N1 2009 influenza A virus, J. Med. Virol., 82, 1-7.
58. VanSciver, M., Miller, S. and Hertzberg, J. (2011) Particle image velocimetry of human cough, Aerosol Sci. Tech., 45, 415-422.
59. Verreault, D., Moineau, S. and Duchaine, C. (2008) Methods for sampling of airborne viruses, Microbiol. Mol. Biol. Rev., 72, 413-444.
60. Voelker, C., Maempel, S. and Kornadt, O. (2014) Measuring the human body's microclimate using a thermal manikin, Indoor Air, 24, 567-579.
61. Wainwright, C.E., France, M.W., O'Rourke, P., Anuj, S., Kidd, T.J., Nissen, M.D., Sloots, T.P., Coulter, C., Ristovski, Z., Hargreaves, M., Rose, B.R., Harbour, C., Bell, S.C. and Fennelly, K.P. (2009) Cough-generated aerosols of Pseudomonas aeruginosa and other Gram-negative bacteria from patients with cystic fibrosis, Thorax, 64, 926-931.
62. Wan, M.P. and Chao, C.Y. (2007) Transport characteristics of expiratory droplets and droplet nuclei in indoor environments with different ventilation airflow patterns, J. Biomech. Eng., 129, 341-353.
63. Wong, B.C., Lee, N., Li, Y., Chan, P.K., Qiu, H., Luo, Z., Lai, R.W., Ngai, K.L., Hui, D.S., Choi, K.W. and Yu, I.T. (2010) Possible role of aerosol transmission in a hospital outbreak of influenza, Clin. Infect. Dis., 51, 1176-1183.
64. Yam, R., Yuen, P.L., Yung, R. and Choy, T. (2011) Rethinking hospital general ward ventilation design using computational fluid dynamics, J. Hosp. Infect., 77, 31-36.
65. Yang, S., Lee, G.W., Chen, C.M., Wu, C.C. and Yu, K.P. (2007) The size and concentration of droplets generated by coughing in human subjects, J. Aerosol Med., 20, 484-494.
66. Yang, W., Elankumaran, S. and Marr, L.C. (2011) Concentrations and size distributions of airborne influenza A viruses measured indoors at a health centre, a day-care centre and on aeroplanes, J. R. Soc. Interface, 8, 1176-1184.
67. Yao, M. and Mainelis, G. (2007) Analysis of portable impactor performance for enumeration of viable bioaerosols, J. Occup. Environ. Hyg., 4, 514-524.
68. Yeh, H.C. and Schum, G.M. (1980) Models of human lung airways and their application to inhaled particle deposition, Bull. Math. Biol., 42, 461-480.
69. Zhang, Y., Gilbertson, K. and Finlay, W.H. (2007) In vivo-in vitro comparison of deposition in three mouth-throat models with Qvar and Turbuhaler inhalers, J. Aerosol Med., 20, 227-235.
70. Zhou, Y. and Cheng, Y.S. (2010) Evaluation of IOM personal sampler at different flow rates, J. Occup. Environ. Hyg., 7, 88-93.
71. Zhu, S., Kato, S. and Yang, J. (2006) Study on transport characteristics of saliva droplets produced by coughing in a calm indoor environment, Build. Environ., 41, 1691-1702.
72. Zuo, Z., Kuehn, T.H., Bekele, A.Z., Mor, S.K., Verma, H., Goyal, S.M., Raynor, P.C. and Pui, D.Y. (2014) Survival of airborne MS2 bacteriophage generated from human saliva, artificial saliva, and cell culture medium, Appl. Environ. Microbiol., 80, 2796-2803.