A " pre-seasonal" hospital outbreak of influenza pneumonia caused by the drift variant A/Victoria/361/2011-like H3N2 viruses, Hong Kong, 2011

Journal of Clinical Virology

Volumn 56, Issue 3, 2013, Pages 303-309

  Chan, Martin C W ^a   Lee, Nelson ^a   Ngai, Karry L K ^a   Wong, Bonnie C K ^a   Lee, May K P ^a   Choi, K W ^a   Lai, Raymond W M ^a   Chan, Paul K S ^a  

^a Prince of Wales Hospital   (China)

Author keywords

Antigenic drift; Influenza; Outbreak; Pneumonia; Vaccine

Indexed keywords

AMINO ACID; ANTIVIRUS AGENT; VIRUS HEMAGGLUTININ;

ADULT; AMINO ACID SEQUENCE; ANTIVIRAL THERAPY; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; EPIDEMIC; HEALTH CARE PERSONNEL; HONG KONG; HOSPITAL; HUMAN; IMMUNOFLUORESCENCE TEST; INFECTION CONTROL; INFECTION RISK; INFLUENZA; INFLUENZA A VICTORIA 361 2011 LIKE H3N2 VIRUS; INFLUENZA VIRUS A H3N2; LABORATORY DIAGNOSIS; MALE; NASOPHARYNGEAL ASPIRATION; PARAINFLUENZA VIRUS INFECTION; PHYLOGENY; PRIORITY JOURNAL; PSYCHIATRIC DEPARTMENT; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SEQUENCE ANALYSIS; VIRUS ISOLATION; VIRUS LOAD; VIRUS PNEUMONIA; VIRUS VIRULENCE;

EID: 84872946216     PISSN: 13866532     EISSN: 18735967     Source Type: Journal    
DOI: 10.1016/j.jcv.2012.11.002     Document Type: Article

References (34)

1. Thompson W.W., Shay D.K., Weintraub E., Brammer L., Bridges C.B., Cox N.J., et al. Influenza-associated hospitalizations in the United States. J Am Med Assoc 2004, 292(11):1333-1340.
2. Nair H., Brooks W.A., Katz M., Roca A., Berkley J.A., Madhi S.A., et al. Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis. Lancet 2011, 378(9807):1917-1930.
3. Lee N., Ison M.G. Diagnosis, management and outcomes of adults hospitalized with influenza. Antivir Ther 2012, 17(1 Pt B):143-157.
4. Estimates of deaths associated with seasonal influenza-United States, 1976-2007. MMWR Morb Mortal Wkly Rep 2010, 59(33):1057-1062.
5. Wright P.F., Thompson J., Karzon D.T. Differing virulence of H1N1 and H3N2 influenza strains. Am J Epidemiol 1980, 112(6):814-819.
6. Kaji M., Watanabe A., Aizawa H. Differences in clinical features between influenza A H1N1, A H3N2, and B in adult patients. Respirology 2003, 8(2):231-233.
7. Simonsen L., Fukuda K., Schonberger L.B., Cox N.J. The impact of influenza epidemics on hospitalizations. J Infect Dis 2000, 181(3):831-837.
8. Smith D.J., Lapedes A.S., de Jong J.C., Bestebroer T.M., Rimmelzwaan G.F., Osterhaus A.D., et al. Mapping the antigenic and genetic evolution of influenza virus. Science 2004, 305(5682):371-376.
9. Russell C.A., Jones T.C., Barr I.G., Cox N.J., Garten R.J., Gregory V., et al. The global circulation of seasonal influenza A(H3N2) viruses. Science 2008, 320(5874):340-346.
10. Goldstein E., Cobey S., Takahashi S., Miller J.C., Lipsitch M. Predicting the epidemic sizes of influenza A/H1N1, A/H3N2, and B: a statistical method. PLoS Med 2011, 8(7):e1001051.
11. Bhat N., Wright J.G., Broder K.R., Murray E.L., Greenberg M.E., Glover M.J., et al. Influenza-associated deaths among children in the United States, 2003-2004. N Engl J Med 2005, 353(24):2559-2567.
12. Schrag S.J., Shay D.K., Gershman K., Thomas A., Craig A.S., Schaffner W., et al. Multistate surveillance for laboratory-confirmed, influenza-associated hospitalizations in children: 2003-2004. Pediatr Infect Dis J 2006, 25(5):395-400.
13. Influenza virus characterisation, Summary Europe. European Centre for Disease Prevention and Control, Available at ; February 2012. http://ecdc.europa.eu/en/publications/Publications/Forms/ECDC_DispForm.a spx%3FID=828.
14. Wong B.C., Lee N., Li Y., Chan P.K., Qiu H., Luo Z., et al. Possible role of aerosol transmission in a hospital outbreak of influenza. Clin Infect Dis 2010, 51(10):1176-1183.
15. Lee N., Hui D., Wu A., Chan P., Cameron P., Joynt G.M., et al. A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med 2003, 348(20):1986-1994.
16. Lee N., Choi K.W., Chan P.K., Hui D.S., Lui G.C., Wong B.C., et al. Outcomes of adults hospitalised with severe influenza. Thorax 2010, 65(6):510-515.
17. Lee N., Cockram C.S., Chan P.K., Hui D.S., Choi K.W., Sung J.J. Antiviral treatment for patients hospitalized with severe influenza infection may affect clinical outcomes. Clin Infect Dis 2008, 46(8):1323-1324.
18. Lee N., Wong C.K., Chan P.K., Lun S.W., Lui G., Wong B., et al. Hypercytokinemia and hyperactivation of phospho-p38 mitogen-activated protein kinase in severe human influenza A virus infection. Clin Infect Dis 2007, 45(6):723-731.
19. Lee N., Chan P.K., Hui D.S., Rainer T.H., Wong E., Choi K.W., et al. Viral loads and duration of viral shedding in adult patients hospitalized with influenza. J Infect Dis 2009, 200(4):492-500.
20. Lee N., Chan P.K., Wong C.K., Wong K.T., Choi K.W., Joynt G.M., et al. Viral clearance and inflammatory response patterns in adults hospitalized for pandemic 2009 influenza A(H1N1) virus pneumonia. Antivir Ther 2011, 16(2):237-247.
21. Tang J.W., Ngai K.L., Lam W.Y., Chan P.K. Seasonality of influenza A(H3N2) virus: a Hong Kong perspective (1997-2006). PLoS ONE 2008, 3(7):e2768.
22. Wiley D.C., Wilson I.A., Skehel J.J. Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation. Nature 1981, 289(5796):373-378.
23. Lina B., Bouscambert M., Enouf V., Rousset D., Valette M., van der Werf S. S-OtrH3N2 viruses: use of sequence data for description of the molecular characteristics of the viruses and their relatedness to previously circulating H3N2 human viruses. Euro Surveill 2011, 16(50):20039.
24. Wilson I.A., Skehel J.J., Wiley D.C. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3Å resolution. Nature 1981, 289(5796):366-373.
25. Flu Express. Centre for Health Protection, Department of Health, The Government of the Hong Kong Special Administrative Region, Available at [accessed 26.07.12]. http://www.chp.gov.hk/files/pdf/flu_express_week28_19_7_2012.pdf.
26. Lackenby A., Thompson C.I., Democratis J. The potential impact of neuraminidase inhibitor resistant influenza. Curr Opin Infect Dis 2008, 21(6):626-638.
27. Seasonal influenza fact sheet. WHO, Available at [accessed 16.04.12]. http://www.who.int/mediacentre/factsheets/fs211/en/.
28. Press Release. Centre for Health Protection, Department of Health, The Government of the Hong Kong Special Administrative Region, Available at [accessed 26.07.12]. http://www.info.gov.hk/gia/general/201207/24/P201207240819.htm.
29. WHO information for laboratory diagnosis of pandemic (H1N1) 2009 virus in humans-revised, Available at . [accessed 13.04.12]. http://www.who.int/entity/csr/resources/publications/swineflu/WHO_Diagno stic_RecommendationsH1N1_20090521.pdf.
30. Chartrand C., Leeflang M.M., Minion J., Brewer T., Pai M. Accuracy of rapid influenza diagnostic tests: a meta-analysis. Ann Intern Med 2012, 156(7):500-511.
31. Everitt A.R., Clare S., Pertel T., John S.P., Wash R.S., Smith S.E., et al. IFITM3 restricts the morbidity and mortality associated with influenza. Nature 2012, 484(7395):519-523.
32. van Riel D., Munster V.J., de Wit E., Rimmelzwaan G.F., Fouchier R.A., Osterhaus A.D., et al. H5N1 virus attachment to lower respiratory tract. Science 2006, 312(5772):399.
33. Galiano M., Johnson B.F., Myers R., Ellis J., Daniels R., Zambon M. Fatal cases of influenza A(H3N2) in children: insights from whole genome sequence analysis. PLoS ONE 2012, 7(3):e33166.
34. Memoli M.J., Jagger B.W., Dugan V.G., Qi L., Jackson J.P., Taubenberger J.K. Recent human influenza A/H3N2 virus evolution driven by novel selection factors in addition to antigenic drift. J Infect Dis 2009, 200(8):1232-1241.