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Volumn 25, Issue 2, 2015, Pages 59-65

Effects of growth hormone-releasing hormone on visceral fat, metabolic, and cardiovascular indices in human studies

Author keywords

Cardiovascular risk; Growth hormone; Growth hormone releasing hormone; Obesity; Visceral obesity

Indexed keywords

C REACTIVE PROTEIN; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR DERIVATIVE; IMMUNOGLOBULIN G ANTIBODY; PLACEBO; RECOMBINANT GROWTH HORMONE; SOMATOMEDIN C; STAT5B PROTEIN; TESAMORELIN; TRIACYLGLYCEROL; GROWTH HORMONE RELEASING FACTOR; HUMAN GROWTH HORMONE;

EID: 84924943365     PISSN: 10966374     EISSN: 15322238     Source Type: Journal    
DOI: 10.1016/j.ghir.2014.12.005     Document Type: Review
Times cited : (41)

References (84)
  • 1
    • 0025333249 scopus 로고
    • Premature mortality due to cardiovascular disease in hypopituitarism
    • (1990/8/4)
    • Rosen T., Bengtsson B.-A. Premature mortality due to cardiovascular disease in hypopituitarism. Lancet 1990, 336(8710):285-288. (1990/8/4).
    • (1990) Lancet , vol.336 , Issue.8710 , pp. 285-288
    • Rosen, T.1    Bengtsson, B.-A.2
  • 3
    • 17844368602 scopus 로고    scopus 로고
    • Short-term effects of growth hormone (GH) treatment or deprivation on cardiovascular risk parameters and intima-media thickness at carotid arteries in patients with severe GH deficiency
    • Colao A., Di Somma C., Rota F., Pivonello R., Savanelli M.C., Spiezia S., et al. Short-term effects of growth hormone (GH) treatment or deprivation on cardiovascular risk parameters and intima-media thickness at carotid arteries in patients with severe GH deficiency. J. Clin. Endocrinol. Metab. Apr 2005, 90(4):2056-2062.
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , Issue.4 , pp. 2056-2062
    • Colao, A.1    Di Somma, C.2    Rota, F.3    Pivonello, R.4    Savanelli, M.C.5    Spiezia, S.6
  • 4
    • 33744955981 scopus 로고    scopus 로고
    • The natural history of partial growth hormone deficiency in adults: a prospective study on the cardiovascular risk and atherosclerosis
    • Colao A., Di Somma C., Spiezia S., Rota F., Pivonello R., Savastano S., et al. The natural history of partial growth hormone deficiency in adults: a prospective study on the cardiovascular risk and atherosclerosis. J. Clin. Endocrinol. Metab. Jun 2006, 91(6):2191-2200.
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , Issue.6 , pp. 2191-2200
    • Colao, A.1    Di Somma, C.2    Spiezia, S.3    Rota, F.4    Pivonello, R.5    Savastano, S.6
  • 5
    • 33746370734 scopus 로고    scopus 로고
    • Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults-a KIMS database analysis
    • Abs R., Feldt-Rasmussen U., Mattsson A.F., Monson J.P., Bengtsson B.A., Goth M.I., et al. Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults-a KIMS database analysis. Eur. J. Endocrinol. Jul 2006, 155(1):79-90.
    • (2006) Eur. J. Endocrinol. , vol.155 , Issue.1 , pp. 79-90
    • Abs, R.1    Feldt-Rasmussen, U.2    Mattsson, A.F.3    Monson, J.P.4    Bengtsson, B.A.5    Goth, M.I.6
  • 6
    • 79956291628 scopus 로고    scopus 로고
    • Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline
    • Molitch M.E., Clemmons D.R., Malozowski S., Merriam G.R., Vance M.L. Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline. J. Clin. Endocrinol. Metab. Jun 2011, 96(6):1587-1609.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , Issue.6 , pp. 1587-1609
    • Molitch, M.E.1    Clemmons, D.R.2    Malozowski, S.3    Merriam, G.R.4    Vance, M.L.5
  • 7
    • 51749105265 scopus 로고    scopus 로고
    • Growth hormone treatment on atherosclerosis: results of a 5-year open, prospective, controlled study in male patients with severe growth hormone deficiency
    • Colao A., Di Somma C., Spiezia S., Savastano S., Rota F., Savanelli M.C., et al. Growth hormone treatment on atherosclerosis: results of a 5-year open, prospective, controlled study in male patients with severe growth hormone deficiency. J. Clin. Endocrinol. Metab. Sep 2008, 93(9):3416-3424.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , Issue.9 , pp. 3416-3424
    • Colao, A.1    Di Somma, C.2    Spiezia, S.3    Savastano, S.4    Rota, F.5    Savanelli, M.C.6
  • 8
    • 76149125135 scopus 로고    scopus 로고
    • Growth hormone deficiency after treatment of acromegaly: a randomized, placebo-controlled study of growth hormone replacement
    • Miller K.K., Wexler T., Fazeli P., Gunnell L., Graham G.J., Beauregard C., et al. Growth hormone deficiency after treatment of acromegaly: a randomized, placebo-controlled study of growth hormone replacement. J. Clin. Endocrinol. Metab. Feb 2010, 95(2):567-577.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , Issue.2 , pp. 567-577
    • Miller, K.K.1    Wexler, T.2    Fazeli, P.3    Gunnell, L.4    Graham, G.J.5    Beauregard, C.6
  • 9
    • 35948976925 scopus 로고    scopus 로고
    • Effect of growth hormone on body composition and visceral adiposity in middle-aged men with visceral obesity
    • Pasarica M., Zachwieja J.J., Dejonge L., Redman S., Smith S.R. Effect of growth hormone on body composition and visceral adiposity in middle-aged men with visceral obesity. J. Clin. Endocrinol. Metab. Nov 2007, 92(11):4265-4270.
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , Issue.11 , pp. 4265-4270
    • Pasarica, M.1    Zachwieja, J.J.2    Dejonge, L.3    Redman, S.4    Smith, S.R.5
  • 11
    • 0030450507 scopus 로고    scopus 로고
    • Growth hormone versus placebo treatment for one year in growth hormone deficient adults: increase in exercise capacity and normalization of body composition
    • Jorgensen J.O., Vahl N., Hansen T.B., Thuesen L., Hagen C., Christiansen J.S. Growth hormone versus placebo treatment for one year in growth hormone deficient adults: increase in exercise capacity and normalization of body composition. Clin. Endocrinol. (Oxf) 1996 Dec, 45(6):681-688.
    • (1996) Clin. Endocrinol. (Oxf) , vol.45 , Issue.6 , pp. 681-688
    • Jorgensen, J.O.1    Vahl, N.2    Hansen, T.B.3    Thuesen, L.4    Hagen, C.5    Christiansen, J.S.6
  • 12
    • 84883688944 scopus 로고    scopus 로고
    • Effects of GH on body composition and cardiovascular risk markers in young men with abdominal obesity
    • Bredella M.A., Gerweck A.V., Lin E., Landa M.G., Torriani M., Schoenfeld D.A., et al. Effects of GH on body composition and cardiovascular risk markers in young men with abdominal obesity. J. Clin. Endocrinol. Metab. 2013, 98(9):3864-3872.
    • (2013) J. Clin. Endocrinol. Metab. , vol.98 , Issue.9 , pp. 3864-3872
    • Bredella, M.A.1    Gerweck, A.V.2    Lin, E.3    Landa, M.G.4    Torriani, M.5    Schoenfeld, D.A.6
  • 13
    • 0031057076 scopus 로고    scopus 로고
    • Growth hormone treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism, and reduces diastolic blood pressure
    • Johannsson G., Marin P., Lonn L., Ottosson M., Stenlof K., Bjorntorp P., et al. Growth hormone treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism, and reduces diastolic blood pressure. J. Clin. Endocrinol. Metab. 1997, 82(3):727-734.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , Issue.3 , pp. 727-734
    • Johannsson, G.1    Marin, P.2    Lonn, L.3    Ottosson, M.4    Stenlof, K.5    Bjorntorp, P.6
  • 14
    • 48749093932 scopus 로고    scopus 로고
    • Low-dose physiological growth hormone in patients with HIV and abdominal fat accumulation: a randomized controlled trial
    • Lo J., You S.M., Canavan B., Liebau J., Beltrani G., Koutkia P., et al. Low-dose physiological growth hormone in patients with HIV and abdominal fat accumulation: a randomized controlled trial. JAMA Aug 6 2008, 300(5):509-519.
    • (2008) JAMA , vol.300 , Issue.5 , pp. 509-519
    • Lo, J.1    You, S.M.2    Canavan, B.3    Liebau, J.4    Beltrani, G.5    Koutkia, P.6
  • 15
    • 84859415664 scopus 로고    scopus 로고
    • Effects of GH in women with abdominal adiposity: a 6-month randomized, double-blind, placebo-controlled trial
    • Bredella M.A., Lin E., Brick D.J., Gerweck A.V., Harrington L.M., Torriani M., et al. Effects of GH in women with abdominal adiposity: a 6-month randomized, double-blind, placebo-controlled trial. Eur. J. Endocrinol. 2012 Apr, 166(4):601-611.
    • (2012) Eur. J. Endocrinol. , vol.166 , Issue.4 , pp. 601-611
    • Bredella, M.A.1    Lin, E.2    Brick, D.J.3    Gerweck, A.V.4    Harrington, L.M.5    Torriani, M.6
  • 16
    • 0025787687 scopus 로고
    • Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) ceretory bursts and the half-life of endogenous GH in healthy men
    • Iranmanesh A., Lizarralde G., Veldhuis J.D. Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) ceretory bursts and the half-life of endogenous GH in healthy men. J. Clin. Endocrinol. Metab. 1991, 73:1081-1088.
    • (1991) J. Clin. Endocrinol. Metab. , vol.73 , pp. 1081-1088
    • Iranmanesh, A.1    Lizarralde, G.2    Veldhuis, J.D.3
  • 17
    • 0029057791 scopus 로고
    • Pulsatile growth hormone secretion in normal-weight and obese men: differential metabolic regulation during energy restriction
    • Riedel M., Hoeft B., Blum W.F., von zur Muhlen A., Brabant G. Pulsatile growth hormone secretion in normal-weight and obese men: differential metabolic regulation during energy restriction. Metabolism May 1995, 44(5):605-610.
    • (1995) Metabolism , vol.44 , Issue.5 , pp. 605-610
    • Riedel, M.1    Hoeft, B.2    Blum, W.F.3    von zur Muhlen, A.4    Brabant, G.5
  • 18
    • 0026716395 scopus 로고
    • Arginine potentiates but does not restore the blunted growth hormone response to growth hormone-releasing hormone in obesity
    • Ghigo E., Procopio M., Boffano G.M., Arvat E., Valente F., Maccario M., et al. Arginine potentiates but does not restore the blunted growth hormone response to growth hormone-releasing hormone in obesity. Metabolism 1992, 41(5):560-563.
    • (1992) Metabolism , vol.41 , Issue.5 , pp. 560-563
    • Ghigo, E.1    Procopio, M.2    Boffano, G.M.3    Arvat, E.4    Valente, F.5    Maccario, M.6
  • 19
    • 0025973802 scopus 로고
    • Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man
    • Veldhuis J.D., Iranmanesh A., Ho K.K., Waters M.J., Johnson M.L., Lizarralde G. Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man. J. Clin. Endocrinol. Metab. 1991, 72(1):51-59.
    • (1991) J. Clin. Endocrinol. Metab. , vol.72 , Issue.1 , pp. 51-59
    • Veldhuis, J.D.1    Iranmanesh, A.2    Ho, K.K.3    Waters, M.J.4    Johnson, M.L.5    Lizarralde, G.6
  • 20
    • 0021855117 scopus 로고
    • Impaired growth hormone response to growth hormone releasing factor and insulin-hypoglycaemia in obesity
    • Kopelman P.G., Noonan K., Goulton R., Forrest A.J. Impaired growth hormone response to growth hormone releasing factor and insulin-hypoglycaemia in obesity. Clin. Endocrinol. (Oxf) Jul 1985, 23(1):87-94.
    • (1985) Clin. Endocrinol. (Oxf) , vol.23 , Issue.1 , pp. 87-94
    • Kopelman, P.G.1    Noonan, K.2    Goulton, R.3    Forrest, A.J.4
  • 21
    • 0021746013 scopus 로고
    • Impaired growth hormone responses to growth hormone-releasing factor in obesity. A pituitary defect reversed with weight reduction
    • Williams T., Berelowitz M., Joffe S.N., Thorner M.O., Rivier J., Vale W., et al. Impaired growth hormone responses to growth hormone-releasing factor in obesity. A pituitary defect reversed with weight reduction. N. Engl. J. Med. Nov 29 1984, 311(22):1403-1407.
    • (1984) N. Engl. J. Med. , vol.311 , Issue.22 , pp. 1403-1407
    • Williams, T.1    Berelowitz, M.2    Joffe, S.N.3    Thorner, M.O.4    Rivier, J.5    Vale, W.6
  • 22
    • 0028953083 scopus 로고
    • Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects
    • Rasmussen M.H., Hvidberg A., Juul A., Main K.M., Gotfredsen A., Skakkebaek N.E., et al. Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects. J. Clin. Endocrinol. Metab. Apr 1995, 80(4):1407-1415.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , Issue.4 , pp. 1407-1415
    • Rasmussen, M.H.1    Hvidberg, A.2    Juul, A.3    Main, K.M.4    Gotfredsen, A.5    Skakkebaek, N.E.6
  • 23
    • 0030737928 scopus 로고    scopus 로고
    • Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults
    • Vahl N., Jorgensen J.O., Skjaerbaek C., Veldhuis J.D., Orskov H., Christiansen J.S. Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults. Am. J. Physiol. Jun 1997, 272(6 Pt 1):E1108-E1116.
    • (1997) Am. J. Physiol. , vol.272 , Issue.6 , pp. E1108-E1116
    • Vahl, N.1    Jorgensen, J.O.2    Skjaerbaek, C.3    Veldhuis, J.D.4    Orskov, H.5    Christiansen, J.S.6
  • 25
    • 57349141683 scopus 로고    scopus 로고
    • The effects of central adiposity on growth hormone (GH) response to GH-releasing hormone-arginine stimulation testing in men
    • Makimura H., Stanley T., Mun D., You S.M., Grinspoon S. The effects of central adiposity on growth hormone (GH) response to GH-releasing hormone-arginine stimulation testing in men. J. Clin. Endocrinol. Metab. Nov 2008, 93(11):4254-4260.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , Issue.11 , pp. 4254-4260
    • Makimura, H.1    Stanley, T.2    Mun, D.3    You, S.M.4    Grinspoon, S.5
  • 26
    • 52649130278 scopus 로고    scopus 로고
    • Lower growth hormone and higher cortisol are associated with greater visceral adiposity, intramyocellular lipids, and insulin resistance in overweight girls
    • Misra M., Bredella M.A., Tsai P., Mendes N., Miller K.K., Klibanski A. Lower growth hormone and higher cortisol are associated with greater visceral adiposity, intramyocellular lipids, and insulin resistance in overweight girls. Am. J. Physiol. Endocrinol. Metab. Aug 2008, 295(2):E385-E392.
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.295 , Issue.2 , pp. E385-E392
    • Misra, M.1    Bredella, M.A.2    Tsai, P.3    Mendes, N.4    Miller, K.K.5    Klibanski, A.6
  • 27
    • 79952290754 scopus 로고    scopus 로고
    • Rapid suppression of growth hormone concentration by overeating: potential mediation by hyperinsulinemia
    • Cornford A.S., Barkan A.L., Horowitz J.F. Rapid suppression of growth hormone concentration by overeating: potential mediation by hyperinsulinemia. J. Clin. Endocrinol. Metab. Mar 2011, 96(3):824-830.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , Issue.3 , pp. 824-830
    • Cornford, A.S.1    Barkan, A.L.2    Horowitz, J.F.3
  • 28
    • 33646815305 scopus 로고    scopus 로고
    • Impact of obesity on the growth hormone axis: evidence for a direct inhibitory effect of hyperinsulinemia on pituitary function
    • Luque R.M., Kineman R.D. Impact of obesity on the growth hormone axis: evidence for a direct inhibitory effect of hyperinsulinemia on pituitary function. Endocrinology Jun 2006, 147(6):2754-2763.
    • (2006) Endocrinology , vol.147 , Issue.6 , pp. 2754-2763
    • Luque, R.M.1    Kineman, R.D.2
  • 29
    • 33747881858 scopus 로고    scopus 로고
    • Examination of the direct effects of metabolic factors on somatotrope function in a non-human primate model, Papio anubis
    • Luque R.M., Gahete M.D., Valentine R.J., Kineman R.D. Examination of the direct effects of metabolic factors on somatotrope function in a non-human primate model, Papio anubis. J. Mol. Endocrinol. Aug 2006, 37(1):25-38.
    • (2006) J. Mol. Endocrinol. , vol.37 , Issue.1 , pp. 25-38
    • Luque, R.M.1    Gahete, M.D.2    Valentine, R.J.3    Kineman, R.D.4
  • 30
    • 0023616485 scopus 로고
    • Free fatty acids block growth hormone (GH) releasing hormone-stimulated GH secretion in man directly at the pituitary
    • Casanueva F.F., Villanueva L., Dieguez C., Diaz Y., Cabranes J.A., Szoke B., et al. Free fatty acids block growth hormone (GH) releasing hormone-stimulated GH secretion in man directly at the pituitary. J. Clin. Endocrinol. Metab. Oct 1987, 65(4):634-642.
    • (1987) J. Clin. Endocrinol. Metab. , vol.65 , Issue.4 , pp. 634-642
    • Casanueva, F.F.1    Villanueva, L.2    Dieguez, C.3    Diaz, Y.4    Cabranes, J.A.5    Szoke, B.6
  • 31
    • 0029935185 scopus 로고    scopus 로고
    • Impaired growth hormone secretion in obese subjects is partially reversed by acipimox-mediated plasma free fatty acid depression
    • Cordido F., Peino R., Penalva A., Alvarez C.V., Casanueva F.F., Dieguez C. Impaired growth hormone secretion in obese subjects is partially reversed by acipimox-mediated plasma free fatty acid depression. J. Clin. Endocrinol. Metab. Mar 1996, 81(3):914-918.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , Issue.3 , pp. 914-918
    • Cordido, F.1    Peino, R.2    Penalva, A.3    Alvarez, C.V.4    Casanueva, F.F.5    Dieguez, C.6
  • 32
    • 23844482496 scopus 로고    scopus 로고
    • The cut-off limits of the GH response to GH-releasing hormone-arginine test related to body mass index
    • Corneli G., Di Somma C., Baldelli R., Rovere S., Gasco V., Croce C.G., et al. The cut-off limits of the GH response to GH-releasing hormone-arginine test related to body mass index. Eur. J. Endocrinol. Aug 2005, 153(2):257-264.
    • (2005) Eur. J. Endocrinol. , vol.153 , Issue.2 , pp. 257-264
    • Corneli, G.1    Di Somma, C.2    Baldelli, R.3    Rovere, S.4    Gasco, V.5    Croce, C.G.6
  • 33
    • 47549103137 scopus 로고    scopus 로고
    • Growth hormone deficiency by growth hormone releasing hormone-arginine testing criteria predicts increased cardiovascular risk markers in normal young overweight and obese women
    • Utz A.L., Yamamoto A., Hemphill L., Miller K.K. Growth hormone deficiency by growth hormone releasing hormone-arginine testing criteria predicts increased cardiovascular risk markers in normal young overweight and obese women. J. Clin. Endocrinol. Metab. Jul 2008, 93(7):2507-2514.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , Issue.7 , pp. 2507-2514
    • Utz, A.L.1    Yamamoto, A.2    Hemphill, L.3    Miller, K.K.4
  • 34
    • 77952804496 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome in moderately-severely obese subjects with and without growth hormone deficiency
    • Di Somma C., Pivonello R., Pizza G., De Rosa A., Lombardi G., Colao A., et al. Prevalence of the metabolic syndrome in moderately-severely obese subjects with and without growth hormone deficiency. J. Endocrinol. Investig. Mar 2010, 33(3):171-177.
    • (2010) J. Endocrinol. Investig. , vol.33 , Issue.3 , pp. 171-177
    • Di Somma, C.1    Pivonello, R.2    Pizza, G.3    De Rosa, A.4    Lombardi, G.5    Colao, A.6
  • 35
    • 73249120020 scopus 로고    scopus 로고
    • Reduced growth hormone secretion is associated with increased carotid intima-media thickness in obesity
    • Makimura H., Stanley T., Mun D., Chen C., Wei J., Connelly J.M., et al. Reduced growth hormone secretion is associated with increased carotid intima-media thickness in obesity. J. Clin. Endocrinol. Metab. Dec 2009, 94(12):5131-5138.
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , Issue.12 , pp. 5131-5138
    • Makimura, H.1    Stanley, T.2    Mun, D.3    Chen, C.4    Wei, J.5    Connelly, J.M.6
  • 36
    • 33746061742 scopus 로고    scopus 로고
    • GH peak response to GHRH-arginine: relationship to insulin resistance and other cardiovascular risk factors in a population of adults aged 50-90
    • Carmichael J.D., Danoff A., Milani D., Roubenoff R., Lesser M.L., Livote E., et al. GH peak response to GHRH-arginine: relationship to insulin resistance and other cardiovascular risk factors in a population of adults aged 50-90. Clin. Endocrinol. (Oxf) Aug 2006, 65(2):169-177.
    • (2006) Clin. Endocrinol. (Oxf) , vol.65 , Issue.2 , pp. 169-177
    • Carmichael, J.D.1    Danoff, A.2    Milani, D.3    Roubenoff, R.4    Lesser, M.L.5    Livote, E.6
  • 37
    • 84855428936 scopus 로고    scopus 로고
    • Reduced growth hormone secretion in obesity is associated with smaller LDL and HDL particle size
    • Makimura H., Feldpausch M.N., Stanley T.L., Sun N., Grinspoon S.K. Reduced growth hormone secretion in obesity is associated with smaller LDL and HDL particle size. Clin. Endocrinol. (Oxf) Feb 2012, 76(2):220-227.
    • (2012) Clin. Endocrinol. (Oxf) , vol.76 , Issue.2 , pp. 220-227
    • Makimura, H.1    Feldpausch, M.N.2    Stanley, T.L.3    Sun, N.4    Grinspoon, S.K.5
  • 38
    • 27644457743 scopus 로고    scopus 로고
    • Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study
    • Yusuf S., Hawken S., Ounpuu S., Bautista L., Franzosi M.G., Commerford P., et al. Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study. Lancet Nov 5 2005, 366(9497):1640-1649.
    • (2005) Lancet , vol.366 , Issue.9497 , pp. 1640-1649
    • Yusuf, S.1    Hawken, S.2    Ounpuu, S.3    Bautista, L.4    Franzosi, M.G.5    Commerford, P.6
  • 40
    • 79953778485 scopus 로고    scopus 로고
    • Association between visceral adipose tissue area and coronary plaque morphology assessed by CT angiography
    • Ohashi N., Yamamoto H., Horiguchi J., Kitagawa T., Kunita E., Utsunomiya H., et al. Association between visceral adipose tissue area and coronary plaque morphology assessed by CT angiography. JACC Cardiovasc. Imaging Sep 2010, 3(9):908-917.
    • (2010) JACC Cardiovasc. Imaging , vol.3 , Issue.9 , pp. 908-917
    • Ohashi, N.1    Yamamoto, H.2    Horiguchi, J.3    Kitagawa, T.4    Kunita, E.5    Utsunomiya, H.6
  • 41
    • 80054949354 scopus 로고    scopus 로고
    • Fatty liver, abdominal visceral fat, and cardiometabolic risk factors: the Jackson Heart Study
    • Liu J., Fox C.S., Hickson D., Bidulescu A., Carr J.J., Taylor H.A. Fatty liver, abdominal visceral fat, and cardiometabolic risk factors: the Jackson Heart Study. Arterioscler. Thromb. Vasc. Biol. Nov 2011, 31(11):2715-2722.
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , Issue.11 , pp. 2715-2722
    • Liu, J.1    Fox, C.S.2    Hickson, D.3    Bidulescu, A.4    Carr, J.J.5    Taylor, H.A.6
  • 42
    • 78650072135 scopus 로고    scopus 로고
    • Impact of abdominal visceral and subcutaneous adipose tissue on cardiometabolic risk factors: the Jackson Heart Study
    • Liu J., Fox C.S., Hickson D.A., May W.D., Hairston K.G., Carr J.J., et al. Impact of abdominal visceral and subcutaneous adipose tissue on cardiometabolic risk factors: the Jackson Heart Study. J. Clin. Endocrinol. Metab. Dec 2010, 95(12):5419-5426.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , Issue.12 , pp. 5419-5426
    • Liu, J.1    Fox, C.S.2    Hickson, D.A.3    May, W.D.4    Hairston, K.G.5    Carr, J.J.6
  • 43
    • 80655130456 scopus 로고    scopus 로고
    • Preferential Fat deposition in subcutaneous versus visceral depots is associated with insulin sensitivity
    • McLaughlin T., Lamendola C., Liu A., Abbasi F. Preferential Fat deposition in subcutaneous versus visceral depots is associated with insulin sensitivity. J. Clin. Endocrinol. Metab. 2011, 96(11):E1756-E1760.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , Issue.11 , pp. E1756-E1760
    • McLaughlin, T.1    Lamendola, C.2    Liu, A.3    Abbasi, F.4
  • 44
    • 77953612080 scopus 로고    scopus 로고
    • Gluteofemoral body fat as a determinant of metabolic health
    • Manolopoulos K.N., Karpe F., Frayn K.N. Gluteofemoral body fat as a determinant of metabolic health. Int. J. Obes. (Lond.) Jun 2010, 34(6):949-959.
    • (2010) Int. J. Obes. (Lond.) , vol.34 , Issue.6 , pp. 949-959
    • Manolopoulos, K.N.1    Karpe, F.2    Frayn, K.N.3
  • 45
    • 84866395319 scopus 로고    scopus 로고
    • Dysfunctional adiposity and the risk of prediabetes and type 2 diabetes in obese adults
    • Neeland I.J., Turer A.T., Ayers C.R., Powell-Wiley T.M., Vega G.L., Farzaneh-Far R., et al. Dysfunctional adiposity and the risk of prediabetes and type 2 diabetes in obese adults. JAMA Sep 19 2012, 308(11):1150-1159.
    • (2012) JAMA , vol.308 , Issue.11 , pp. 1150-1159
    • Neeland, I.J.1    Turer, A.T.2    Ayers, C.R.3    Powell-Wiley, T.M.4    Vega, G.L.5    Farzaneh-Far, R.6
  • 46
    • 84861341836 scopus 로고    scopus 로고
    • Visceral abdominal fat accumulation predicts the progression of noncalcified coronary plaque
    • Imai A., Komatsu S., Ohara T., Kamata T., Yoshida J., Miyaji K., et al. Visceral abdominal fat accumulation predicts the progression of noncalcified coronary plaque. Atherosclerosis Jun 2012, 222(2):524-529.
    • (2012) Atherosclerosis , vol.222 , Issue.2 , pp. 524-529
    • Imai, A.1    Komatsu, S.2    Ohara, T.3    Kamata, T.4    Yoshida, J.5    Miyaji, K.6
  • 48
    • 2942526828 scopus 로고    scopus 로고
    • Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease
    • Klein S., Fontana L., Young V.L., Coggan A.R., Kilo C., Patterson B.W., et al. Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. N. Engl. J. Med. Jun 17 2004, 350(25):2549-2557.
    • (2004) N. Engl. J. Med. , vol.350 , Issue.25 , pp. 2549-2557
    • Klein, S.1    Fontana, L.2    Young, V.L.3    Coggan, A.R.4    Kilo, C.5    Patterson, B.W.6
  • 49
    • 58149299995 scopus 로고    scopus 로고
    • Long-term effects of large-volume liposuction on metabolic risk factors for coronary heart disease
    • Mohammed B.S., Cohen S., Reeds D., Young V.L., Klein S. Long-term effects of large-volume liposuction on metabolic risk factors for coronary heart disease. Obesity (Silver Spring) Dec 2008, 16(12):2648-2651.
    • (2008) Obesity (Silver Spring) , vol.16 , Issue.12 , pp. 2648-2651
    • Mohammed, B.S.1    Cohen, S.2    Reeds, D.3    Young, V.L.4    Klein, S.5
  • 50
    • 0036179818 scopus 로고    scopus 로고
    • A pilot study of long-term effects of a novel obesity treatment: omentectomy in connection with adjustable gastric banding
    • Thorne A., Lonnqvist F., Apelman J., Hellers G., Arner P. A pilot study of long-term effects of a novel obesity treatment: omentectomy in connection with adjustable gastric banding. Int. J. Obes. Relat. Metab. Disord. Feb 2002, 26(2):193-199.
    • (2002) Int. J. Obes. Relat. Metab. Disord. , vol.26 , Issue.2 , pp. 193-199
    • Thorne, A.1    Lonnqvist, F.2    Apelman, J.3    Hellers, G.4    Arner, P.5
  • 51
    • 58149387611 scopus 로고    scopus 로고
    • Effects of recombinant human growth hormone therapy in obesity in adults: a meta analysis
    • Mekala K.C., Tritos N.A. Effects of recombinant human growth hormone therapy in obesity in adults: a meta analysis. J. Clin. Endocrinol. Metab. Jan 2009, 94(1):130-137.
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , Issue.1 , pp. 130-137
    • Mekala, K.C.1    Tritos, N.A.2
  • 52
    • 0028154380 scopus 로고
    • Growth hormone treatment of obese women for 5 wk: effect on body composition and adipose tissue LPL activity
    • Richelsen B., Pedersen S.B., Borglum J.D., Moller-Pedersen T., Jorgensen J., Jorgensen J.O. Growth hormone treatment of obese women for 5 wk: effect on body composition and adipose tissue LPL activity. Am. J. Physiol. Feb 1994, 266(2 Pt 1):E211-E216.
    • (1994) Am. J. Physiol. , vol.266 , Issue.2 , pp. E211-E216
    • Richelsen, B.1    Pedersen, S.B.2    Borglum, J.D.3    Moller-Pedersen, T.4    Jorgensen, J.5    Jorgensen, J.O.6
  • 54
    • 0018581798 scopus 로고
    • Age- and sex-related differences in episodic growth hormone secretion in the rat
    • Eden S. Age- and sex-related differences in episodic growth hormone secretion in the rat. Endocrinology Aug 1979, 105(2):555-560.
    • (1979) Endocrinology , vol.105 , Issue.2 , pp. 555-560
    • Eden, S.1
  • 55
    • 0020214059 scopus 로고
    • Association between plasma level of growth hormone and sex differentiation of hepatic steroid metabolism in the rat
    • Mode A., Gustafsson J.A., Jansson J.O., Eden S., Isaksson O. Association between plasma level of growth hormone and sex differentiation of hepatic steroid metabolism in the rat. Endocrinology Nov 1982, 111(5):1692-1697.
    • (1982) Endocrinology , vol.111 , Issue.5 , pp. 1692-1697
    • Mode, A.1    Gustafsson, J.A.2    Jansson, J.O.3    Eden, S.4    Isaksson, O.5
  • 56
    • 0020788740 scopus 로고
    • Regulation of sexually dimorphic hepatic steroid metabolism by the somatostatin-growth hormone axis
    • Gustafsson J.A., Eden S., Eneroth P., Hokfelt T., Isaksson O., Jansson J.O., et al. Regulation of sexually dimorphic hepatic steroid metabolism by the somatostatin-growth hormone axis. J. Steroid Biochem. Jul 1983, 19(1B):691-698.
    • (1983) J. Steroid Biochem. , vol.19 , Issue.1 B , pp. 691-698
    • Gustafsson, J.A.1    Eden, S.2    Eneroth, P.3    Hokfelt, T.4    Isaksson, O.5    Jansson, J.O.6
  • 57
    • 33744456856 scopus 로고    scopus 로고
    • Growth hormone regulation of sex-dependent liver gene expression
    • Waxman D.J., O'Connor C. Growth hormone regulation of sex-dependent liver gene expression. Mol. Endocrinol. Nov 2006, 20(11):2613-2629.
    • (2006) Mol. Endocrinol. , vol.20 , Issue.11 , pp. 2613-2629
    • Waxman, D.J.1    O'Connor, C.2
  • 58
    • 0032955406 scopus 로고    scopus 로고
    • Down-regulation of liver JAK2-STAT5b signaling by the female plasma pattern of continuous growth hormone stimulation
    • Gebert C.A., Park S.H., Waxman D.J. Down-regulation of liver JAK2-STAT5b signaling by the female plasma pattern of continuous growth hormone stimulation. Mol. Endocrinol. Feb 1999, 13(2):213-227.
    • (1999) Mol. Endocrinol. , vol.13 , Issue.2 , pp. 213-227
    • Gebert, C.A.1    Park, S.H.2    Waxman, D.J.3
  • 59
  • 60
    • 68549132319 scopus 로고    scopus 로고
    • The pattern of growth hormone delivery to peripheral tissues determines insulin-like growth factor-1 and lipolytic responses in obese subjects
    • Surya S., Horowitz J.F., Goldenberg N., Sakharova A., Harber M., Cornford A.S., et al. The pattern of growth hormone delivery to peripheral tissues determines insulin-like growth factor-1 and lipolytic responses in obese subjects. J. Clin. Endocrinol. Metab. Aug 2009, 94(8):2828-2834.
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , Issue.8 , pp. 2828-2834
    • Surya, S.1    Horowitz, J.F.2    Goldenberg, N.3    Sakharova, A.4    Harber, M.5    Cornford, A.S.6
  • 61
    • 77952775017 scopus 로고    scopus 로고
    • Basal, but not pulsatile, growth hormone secretion determines the ambient circulating levels of insulin-like growth factor-I
    • Faje A.T., Barkan A.L. Basal, but not pulsatile, growth hormone secretion determines the ambient circulating levels of insulin-like growth factor-I. J. Clin. Endocrinol. Metab. 2010 May, 95(5):2486-2491.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , Issue.5 , pp. 2486-2491
    • Faje, A.T.1    Barkan, A.L.2
  • 62
    • 0029812622 scopus 로고    scopus 로고
    • Effects of pulsatile delivery of basal growth hormone on lipolysis in humans
    • Cersosimo E., Danou F., Persson M., Miles J.M. Effects of pulsatile delivery of basal growth hormone on lipolysis in humans. Am. J. Physiol. Jul 1996, 271(1 Pt 1):E123-E126.
    • (1996) Am. J. Physiol. , vol.271 , Issue.1 , pp. E123-E126
    • Cersosimo, E.1    Danou, F.2    Persson, M.3    Miles, J.M.4
  • 63
    • 0026686487 scopus 로고
    • Subcutaneous growth hormone-releasing hormone therapy in growth hormone-deficient children: first year of therapy
    • Duck S.C., Schwarz H.P., Costin G., Rapaport R., Arslanian S., Hayek A., et al. Subcutaneous growth hormone-releasing hormone therapy in growth hormone-deficient children: first year of therapy. J. Clin. Endocrinol. Metab. Oct 1992, 75(4):1115-1120.
    • (1992) J. Clin. Endocrinol. Metab. , vol.75 , Issue.4 , pp. 1115-1120
    • Duck, S.C.1    Schwarz, H.P.2    Costin, G.3    Rapaport, R.4    Arslanian, S.5    Hayek, A.6
  • 64
    • 0023642786 scopus 로고
    • Treatment of growth-hormone deficiency with growth-hormone-releasing hormone
    • Ross R.J., Rodda C., Tsagarakis S., Davies P.S., Grossman A., Rees L.H., et al. Treatment of growth-hormone deficiency with growth-hormone-releasing hormone. Lancet 1987, 1(8523):5-8.
    • (1987) Lancet , vol.1 , Issue.8523 , pp. 5-8
    • Ross, R.J.1    Rodda, C.2    Tsagarakis, S.3    Davies, P.S.4    Grossman, A.5    Rees, L.H.6
  • 65
    • 0023877224 scopus 로고
    • Growth hormone releasing hormone or growth hormone treatment in growth hormone insufficiency?
    • Smith P.J., Brook C.G. Growth hormone releasing hormone or growth hormone treatment in growth hormone insufficiency?. Arch. Dis. Child. Jun 1988, 63(6):629-634.
    • (1988) Arch. Dis. Child. , vol.63 , Issue.6 , pp. 629-634
    • Smith, P.J.1    Brook, C.G.2
  • 66
    • 0029924189 scopus 로고    scopus 로고
    • Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy, Geref International Study Group
    • Thorner M., Rochiccioli P., Colle M., Lanes R., Grunt J., Galazka A., et al. Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy, Geref International Study Group. J. Clin. Endocrinol. Metab. 1996, 81(3):1189-1196.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , Issue.3 , pp. 1189-1196
    • Thorner, M.1    Rochiccioli, P.2    Colle, M.3    Lanes, R.4    Grunt, J.5    Galazka, A.6
  • 67
    • 78650902011 scopus 로고    scopus 로고
    • Effects of a growth hormone-releasing hormone analog on endogenous GH pulsatility and insulin sensitivity in healthy men
    • Stanley T.L., Chen C.Y., Branch K.L., Makimura H., Grinspoon S.K. Effects of a growth hormone-releasing hormone analog on endogenous GH pulsatility and insulin sensitivity in healthy men. J. Clin. Endocrinol. Metab. Jan 2011, 96(1):150-158.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , Issue.1 , pp. 150-158
    • Stanley, T.L.1    Chen, C.Y.2    Branch, K.L.3    Makimura, H.4    Grinspoon, S.K.5
  • 69
    • 0942287339 scopus 로고    scopus 로고
    • Metabolic regulation of growth hormone by free fatty acids, somatostatin, and ghrelin in HIV-lipodystrophy
    • Koutkia P., Meininger G., Canavan B., Breu J., Grinspoon S. Metabolic regulation of growth hormone by free fatty acids, somatostatin, and ghrelin in HIV-lipodystrophy. Am. J. Physiol. Endocrinol. Metab. Feb 2004, 286(2):E296-E303.
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.286 , Issue.2 , pp. E296-E303
    • Koutkia, P.1    Meininger, G.2    Canavan, B.3    Breu, J.4    Grinspoon, S.5
  • 70
    • 70449348258 scopus 로고    scopus 로고
    • Relationship of peak growth hormone to cardiovascular parameters, waist circumference, lipids and glucose in HIV-infected patients and healthy adults
    • Lo J., You S.M., Wei J., Canavan B., Grinspoon S. Relationship of peak growth hormone to cardiovascular parameters, waist circumference, lipids and glucose in HIV-infected patients and healthy adults. Clin. Endocrinol. (Oxf) 2009, 71(6):815-822.
    • (2009) Clin. Endocrinol. (Oxf) , vol.71 , Issue.6 , pp. 815-822
    • Lo, J.1    You, S.M.2    Wei, J.3    Canavan, B.4    Grinspoon, S.5
  • 71
    • 1442324033 scopus 로고    scopus 로고
    • Effects of growth hormone on abnormal visceral adipose tissue accumulation and dyslipidemia in HIV-infected patients
    • Kotler D.P., Muurahainen N., Grunfeld C., Wanke C., Thompson M., Saag M., et al. Effects of growth hormone on abnormal visceral adipose tissue accumulation and dyslipidemia in HIV-infected patients. J. Acquir. Immune Defic. Syndr. Mar 1 2004, 35(3):239-252.
    • (2004) J. Acquir. Immune Defic. Syndr. , vol.35 , Issue.3 , pp. 239-252
    • Kotler, D.P.1    Muurahainen, N.2    Grunfeld, C.3    Wanke, C.4    Thompson, M.5    Saag, M.6
  • 73
    • 34347324037 scopus 로고    scopus 로고
    • Recombinant human growth hormone to treat HIV-associated adipose redistribution syndrome: 12week induction and 24-week maintenance therapy
    • Grunfeld C., Thompson M., Brown S.J., Richmond G., Lee D., Muurahainen N., et al. Recombinant human growth hormone to treat HIV-associated adipose redistribution syndrome: 12week induction and 24-week maintenance therapy. J. Acquir. Immune Defic. Syndr. Jul 1 2007, 45(3):286-297.
    • (2007) J. Acquir. Immune Defic. Syndr. , vol.45 , Issue.3 , pp. 286-297
    • Grunfeld, C.1    Thompson, M.2    Brown, S.J.3    Richmond, G.4    Lee, D.5    Muurahainen, N.6
  • 74
    • 3042762914 scopus 로고    scopus 로고
    • Growth hormone-releasing hormone in HIV-infected men with lipodystrophy: a randomized controlled trial
    • Koutkia P., Canavan B., Breu J., Torriani M., Kissko J., Grinspoon S. Growth hormone-releasing hormone in HIV-infected men with lipodystrophy: a randomized controlled trial. JAMA July 14 2004, 292(2):210-218. 10.1001/jama.292.2.210.
    • (2004) JAMA , vol.292 , Issue.2 , pp. 210-218
    • Koutkia, P.1    Canavan, B.2    Breu, J.3    Torriani, M.4    Kissko, J.5    Grinspoon, S.6
  • 75
    • 36849058739 scopus 로고    scopus 로고
    • Metabolic effects of a growth hormone-releasing factor in patients with HIV
    • Falutz J., Allas S., Blot K., Potvin D., Kotler D., Somero M., et al. Metabolic effects of a growth hormone-releasing factor in patients with HIV. N. Engl. J. Med. Dec 6 2007, 357(23):2359-2370.
    • (2007) N. Engl. J. Med. , vol.357 , Issue.23 , pp. 2359-2370
    • Falutz, J.1    Allas, S.2    Blot, K.3    Potvin, D.4    Kotler, D.5    Somero, M.6
  • 76
    • 24044482335 scopus 로고    scopus 로고
    • A placebo-controlled, dose-ranging study of a growth hormone releasing factor in HIV-infected patients with abdominal fat accumulation
    • Falutz J., Allas S., Kotler D., Thompson M., Koutkia P., Albu J., et al. A placebo-controlled, dose-ranging study of a growth hormone releasing factor in HIV-infected patients with abdominal fat accumulation. AIDS Aug 12 2005, 19(12):1279-1287.
    • (2005) AIDS , vol.19 , Issue.12 , pp. 1279-1287
    • Falutz, J.1    Allas, S.2    Kotler, D.3    Thompson, M.4    Koutkia, P.5    Albu, J.6
  • 78
    • 58149273826 scopus 로고    scopus 로고
    • Long-term safety and effects of tesamorelin, a growth hormone-releasing factor analogue, in HIV patients with abdominal fat accumulation
    • Falutz J., Allas S., Mamputu J.C., Potvin D., Kotler D., Somero M., et al. Long-term safety and effects of tesamorelin, a growth hormone-releasing factor analogue, in HIV patients with abdominal fat accumulation. AIDS Sep 12 2008, 22(14):1719-1728.
    • (2008) AIDS , vol.22 , Issue.14 , pp. 1719-1728
    • Falutz, J.1    Allas, S.2    Mamputu, J.C.3    Potvin, D.4    Kotler, D.5    Somero, M.6
  • 79
    • 77956576248 scopus 로고    scopus 로고
    • Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data
    • Falutz J., Mamputu J.C., Potvin D., Moyle G., Soulban G., Loughrey H., et al. Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data. J. Clin. Endocrinol. Metab. Sep 2010, 95(9):4291-4304.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , Issue.9 , pp. 4291-4304
    • Falutz, J.1    Mamputu, J.C.2    Potvin, D.3    Moyle, G.4    Soulban, G.5    Loughrey, H.6
  • 80
    • 79958817976 scopus 로고    scopus 로고
    • Effects of tesamorelin on inflammatory markers in HIV patients with excess abdominal fat: relationship with visceral adipose reduction
    • Stanley T.L., Falutz J., Mamputu J.C., Soulban G., Potvin D., Grinspoon S.K. Effects of tesamorelin on inflammatory markers in HIV patients with excess abdominal fat: relationship with visceral adipose reduction. AIDS Jun 19 2011, 25(10):1281-1288.
    • (2011) AIDS , vol.25 , Issue.10 , pp. 1281-1288
    • Stanley, T.L.1    Falutz, J.2    Mamputu, J.C.3    Soulban, G.4    Potvin, D.5    Grinspoon, S.K.6
  • 81
    • 84861069214 scopus 로고    scopus 로고
    • Reduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin
    • Stanley T.L., Falutz J., Marsolais C., Morin J., Soulban G., Mamputu J.C., et al. Reduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin. Clin. Infect. Dis. Jun 2012, 54(11):1642-1651.
    • (2012) Clin. Infect. Dis. , vol.54 , Issue.11 , pp. 1642-1651
    • Stanley, T.L.1    Falutz, J.2    Marsolais, C.3    Morin, J.4    Soulban, G.5    Mamputu, J.C.6
  • 82
    • 84904543851 scopus 로고    scopus 로고
    • Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial
    • T.L. Stanley, M.N. Feldpausch, J. Oh, K.L. Branch, H. Lee, M. Torriani, et al., Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial, JAMA 312 (4) (Jul 23-30 2014) 380-389.
    • (2014) JAMA , vol.312 , Issue.4 , pp. 380-389
    • Stanley, T.L.1    Feldpausch, M.N.2    Oh, J.3    Branch, K.L.4    Lee, H.5    Torriani, M.6
  • 83
    • 84870753316 scopus 로고    scopus 로고
    • Metabolic effects of a growth hormone-releasing factor in obese subjects with reduced growth hormone secretion: a randomized controlled trial
    • H. Makimura, M.N. Feldpausch, A.M. Rope, L.C. Hemphill, M. Torriani, H. Lee, et al., Metabolic effects of a growth hormone-releasing factor in obese subjects with reduced growth hormone secretion: a randomized controlled trial, J. Clin. Endocrinol. Metab. 97 (12) (Dec 2012) 4769-4779.
    • (2012) J. Clin. Endocrinol. Metab. , vol.97 , Issue.12 , pp. 4769-4779
    • Makimura, H.1    Feldpausch, M.N.2    Rope, A.M.3    Hemphill, L.C.4    Torriani, M.5    Lee, H.6


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