메뉴 건너뛰기




Volumn 81, Issue 3, 1996, Pages 914-918

Impaired growth hormone secretion in obese subjects is partially reversed by acipimox-mediated plasma free fatty acid depression

Author keywords

[No Author keywords available]

Indexed keywords

ACIPIMOX; FATTY ACID; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; HISTIDYL DEXTRO TRYPTOPHYLALANYLTRYPTOPHYL DEXTRO PHENYLALANYLLYSINAMIDE; PLACEBO; PYRIDOSTIGMINE;

EID: 0029935185     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.3.914     Document Type: Article
Times cited : (85)

References (28)
  • 1
    • 0014098603 scopus 로고
    • Effect of arginine on serum levels of insulin and growth hormone in obese subjects
    • Copinschi G, Wegienka LC, Hane S, Forsham PH. 1967 Effect of arginine on serum levels of insulin and growth hormone in obese subjects. Metabolism. 16:485-491.
    • (1967) Metabolism , vol.16 , pp. 485-491
    • Copinschi, G.1    Wegienka, L.C.2    Hane, S.3    Forsham, P.H.4
  • 2
    • 0015698908 scopus 로고
    • Endocrine and metabolic effects of experimental obesity in man
    • Sims EAH, Danforth E, Horton ES, et al. 1973 Endocrine and metabolic effects of experimental obesity in man. Recent Prog Horm Res. 29:457-496.
    • (1973) Recent Prog Horm Res , vol.29 , pp. 457-496
    • Sims, E.A.H.1    Danforth, E.2    Horton, E.S.3
  • 5
    • 0028922330 scopus 로고
    • Influence of metabolic substrates and obesity on growth hormone secretion
    • Dieguez C, Casanueva FF. 1995 Influence of metabolic substrates and obesity on growth hormone secretion. Trends Endocrinol Metab. 6:55-59.
    • (1995) Trends Endocrinol Metab , vol.6 , pp. 55-59
    • Dieguez, C.1    Casanueva, F.F.2
  • 6
    • 0021746013 scopus 로고
    • Impaired growth hormone responses to growth hormone releasing factor in obesity
    • Williams T, Berelowitz M, Joffe SN, et al. 1984 Impaired growth hormone responses to growth hormone releasing factor in obesity. N Engl J Med. 311:1403-1407.
    • (1984) N Engl J Med , vol.311 , pp. 1403-1407
    • Williams, T.1    Berelowitz, M.2    Joffe, S.N.3
  • 7
    • 0022547886 scopus 로고
    • Potentiation of cholinergic tone by pyridostigmine bromide re-instates and potentiates the growth hormone responsiveness to intermittent administration of growth hormone releasing factor in man
    • Copenh
    • Massara F, Ghigo E, Molinati P, et al. 1986 Potentiation of cholinergic tone by pyridostigmine bromide re-instates and potentiates the growth hormone responsiveness to intermittent administration of growth hormone releasing factor in man. Acta Endocrinol (Copenh). 113:12-16.
    • (1986) Acta Endocrinol , vol.113 , pp. 12-16
    • Massara, F.1    Ghigo, E.2    Molinati, P.3
  • 8
    • 0025159237 scopus 로고
    • Effect of enhancement of endogenous cholinergic tone with pyridostigmine on the dose-response relationships of growth hormone-releasing hormone-induced growth hormone secretion in normal subjects
    • Peñalva A, Muruais C, Casanueva FF, Dieguez C. 1990 Effect of enhancement of endogenous cholinergic tone with pyridostigmine on the dose-response relationships of growth hormone-releasing hormone-induced growth hormone secretion in normal subjects. J Clin Endocrinol Metab. 70:324-328.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 324-328
    • Peñalva, A.1    Muruais, C.2    Casanueva, F.F.3    Dieguez, C.4
  • 9
    • 0025274391 scopus 로고
    • Effect of central cholinergic neurotransmission enhancement by pyridostigmine on the growth hormone secretion elicited by clonidine, arginine, or hypoglycemia in normal and obese subjects
    • Cordido F, Dieguez C, Casanueva FF. 1990 Effect of central cholinergic neurotransmission enhancement by pyridostigmine on the growth hormone secretion elicited by clonidine, arginine, or hypoglycemia in normal and obese subjects. J Clin Endocrinol Metab. 70:1361-1370.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 1361-1370
    • Cordido, F.1    Dieguez, C.2    Casanueva, F.F.3
  • 10
    • 0024595628 scopus 로고
    • Cholinergic receptor activation by pyridostigmine restores growth hormone (GH) responsiveness to GH-releasing hormone administration in obese subjects
    • Cordido F, Casanueva FF, Dieguez C. 1989 Cholinergic receptor activation by pyridostigmine restores growth hormone (GH) responsiveness to GH-releasing hormone administration in obese subjects. J Clin Endocrinol Metab. 68:290-293.
    • (1989) J Clin Endocrinol Metab , vol.68 , pp. 290-293
    • Cordido, F.1    Casanueva, F.F.2    Dieguez, C.3
  • 11
    • 0027419864 scopus 로고
    • Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6: Evidence for a marked somatotroph secretory capability in obesity
    • Cordido F, Peñalva A, Dieguez C, Casanueva FF. 1993 Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6: evidence for a marked somatotroph secretory capability in obesity. J Clin Endocrinol Metab. 76:819-823.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 819-823
    • Cordido, F.1    Peñalva, A.2    Dieguez, C.3    Casanueva, F.F.4
  • 12
    • 0021322884 scopus 로고
    • On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone
    • Bowers CY, Momany FA, Reynolds GA, Hong A. 1984 On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology. 114:1537-1545.
    • (1984) Endocrinology , vol.114 , pp. 1537-1545
    • Bowers, C.Y.1    Momany, F.A.2    Reynolds, G.A.3    Hong, A.4
  • 13
    • 0022531052 scopus 로고
    • Effect of obesity on ambient plasma glucose, free fatty acid, insulin, growth hormone and glucagon concentrations
    • Golay A, Swislocki ALM, Chen Y-DI, Jaspan JB, Reaven GM. 1986 Effect of obesity on ambient plasma glucose, free fatty acid, insulin, growth hormone and glucagon concentrations. J Clin Endocrinol Metab. 63:481-484.
    • (1986) J Clin Endocrinol Metab , vol.63 , pp. 481-484
    • Golay, A.1    Swislocki, A.L.M.2    Chen, Y.-D.I.3    Jaspan, J.B.4    Reaven, G.M.5
  • 14
    • 0007621825 scopus 로고
    • Effect of nicotinic acid administration on plasma growth hormone concentrations
    • Irie M, Sakuma M, Tsushima T, Shizume K, Nakao K. 1967 Effect of nicotinic acid administration on plasma growth hormone concentrations. Proc Soc Exp Biol Med. 126:708-711.
    • (1967) Proc Soc Exp Biol Med , vol.126 , pp. 708-711
    • Irie, M.1    Sakuma, M.2    Tsushima, T.3    Shizume, K.4    Nakao, K.5
  • 15
    • 0019142367 scopus 로고
    • Inhibition of lipolysis by nicotinic acid and acipimox
    • Fuccella L, Goldaniga G, Lovisolo P. 1980 Inhibition of lipolysis by nicotinic acid and acipimox. Clin Pharmacol Ther. 28:790-795.
    • (1980) Clin Pharmacol Ther , vol.28 , pp. 790-795
    • Fuccella, L.1    Goldaniga, G.2    Lovisolo, P.3
  • 16
    • 0025007875 scopus 로고
    • Effect of acipimox, a lipid lowering drug on growth hormone (GH) response to GH-releasing hormone in normal subjects
    • Pontiroli AE, Lanzi R, Monti LD, Pozza G. 1990 Effect of acipimox, a lipid lowering drug on growth hormone (GH) response to GH-releasing hormone in normal subjects. J Endocrinol Invest. 13:539-542.
    • (1990) J Endocrinol Invest , vol.13 , pp. 539-542
    • Pontiroli, A.E.1    Lanzi, R.2    Monti, L.D.3    Pozza, G.4
  • 17
    • 0025821611 scopus 로고
    • Growth hormone (GH) auto feedback on GH response to GH-releasing hormone. Role of tree fatty adds and somatostatin
    • Pontiroli AE, Lanzi R, Monti LD, Sandoli E, Pozza G. 1991 Growth hormone (GH) auto feedback on GH response to GH-releasing hormone. Role of tree fatty adds and somatostatin. J Clin Endocrinol Metab. 72:492-495.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 492-495
    • Pontiroli, A.E.1    Lanzi, R.2    Monti, L.D.3    Sandoli, E.4    Pozza, G.5
  • 18
    • 0004257740 scopus 로고
    • Washington DC: U.S. Government Printing Office; NIH publication 79/359
    • Bray GA. 1979 Obesity in America. Washington DC: U.S. Government Printing Office; NIH publication 79/359.
    • (1979) Obesity in America
    • Bray, G.A.1
  • 20
    • 0023850369 scopus 로고
    • Enhanced growth hormone responsiveness to GH-releasing hormone after dietary manipulation in obese and nonobese subjects
    • Kelijman M, Frohman LA. 1988 Enhanced growth hormone responsiveness to GH-releasing hormone after dietary manipulation in obese and nonobese subjects. J Clin Endocrinol Metab. 66.489-494.
    • (1988) J Clin Endocrinol Metab , vol.66 , pp. 489-494
    • Kelijman, M.1    Frohman, L.A.2
  • 21
    • 0027417526 scopus 로고
    • Editorial: A new dimension on the induced release of growth hormone in obese subjects
    • Bowers C. 1993 Editorial: a new dimension on the induced release of growth hormone in obese subjects. J Clin Endocrinol Metab. 76:817-818.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 817-818
    • Bowers, C.1
  • 22
    • 0023616485 scopus 로고
    • Free fatty acids block growth hormone (GH) releasing hormone-stimulated GH secretion in man directly at the pituitary
    • Casanueva FF, Villanueva L, Dieguez C, et al. 1987 Free fatty acids block growth hormone (GH) releasing hormone-stimulated GH secretion in man directly at the pituitary. J Clin Endocrinol Metab. 65:634-642.
    • (1987) J Clin Endocrinol Metab , vol.65 , pp. 634-642
    • Casanueva, F.F.1    Villanueva, L.2    Dieguez, C.3
  • 23
    • 0025733685 scopus 로고
    • Regulation of epidermal-growth-factor-receptor signal transduction by cis-unsaturated fatty acids
    • Casabiell X, Pandiella A, Casanueva FF. 1991 Regulation of epidermal-growth-factor-receptor signal transduction by cis-unsaturated fatty acids. Biochem J 278:679-687.
    • (1991) Biochem J , vol.278 , pp. 679-687
    • Casabiell, X.1    Pandiella, A.2    Casanueva, F.F.3
  • 24
    • 0027193914 scopus 로고
    • Oleic acid blocks epidermal growth factor-activated early intracellular signals without altering the ensuing mitogenic response
    • Casabiell X, Zugaza JL, Pombo CM, Pandiella A, Casanueva FF. 1993 Oleic acid blocks epidermal growth factor-activated early intracellular signals without altering the ensuing mitogenic response. Exp Cell Res. 205:365-373.
    • (1993) Exp Cell Res , vol.205 , pp. 365-373
    • Casabiell, X.1    Zugaza, J.L.2    Pombo, C.M.3    Pandiella, A.4    Casanueva, F.F.5
  • 25
    • 0029913476 scopus 로고    scopus 로고
    • Acipimox-mediated plasma free fatty acid depression per se stimulates growth hormone (GH) secretion in normal subjects and potentiates the response to other GH releasing stimuli
    • Peino R, Cordido F, Peñalva A, Alvarez CV, Dieguez C, Casanueva FF. 1996 Acipimox-mediated plasma free fatty acid depression per se stimulates growth hormone (GH) secretion in normal subjects and potentiates the response to other GH releasing stimuli. J Clin Endocrinol Metab. 81:909-913.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 909-913
    • Peino, R.1    Cordido, F.2    Peñalva, A.3    Alvarez, C.V.4    Dieguez, C.5    Casanueva, F.F.6
  • 26
    • 0028968462 scopus 로고
    • Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: Evidence that GHRP-6 main action is exerted at the hypothalamic level
    • Popovic V, Damjanovic S, Micic D, Djurovic M, Dieguez C, Casanueva FF. 1995 Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: evidence that GHRP-6 main action is exerted at the hypothalamic level. J Clin Endocrinol Metab. 80:942-947.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 942-947
    • Popovic, V.1    Damjanovic, S.2    Micic, D.3    Djurovic, M.4    Dieguez, C.5    Casanueva, F.F.6
  • 27
    • 0029039609 scopus 로고
    • Effects of combined administration of growth hormone (GH)-releasing hormone, GH-releasing peptide and pyridostigmine in normal and obese subjects
    • Cordido F, Peñalva A, Peino R, Casanueva FF, Dieguez C. 1995 Effects of combined administration of growth hormone (GH)-releasing hormone, GH-releasing peptide and pyridostigmine in normal and obese subjects. Metabolism. 44:745-748.
    • (1995) Metabolism , vol.44 , pp. 745-748
    • Cordido, F.1    Peñalva, A.2    Peino, R.3    Casanueva, F.F.4    Dieguez, C.5
  • 28
    • 0025962290 scopus 로고
    • Evidence for a direct pituitary inhibition by free fatty acids of in vivo growth hormone responses to growth hormone-releasing factor in the rat
    • Alvarez CV, Mallo F, Burguera B, Cacicedo L, Dieguez C, Casanueva FF. 1991 Evidence for a direct pituitary inhibition by free fatty acids of in vivo growth hormone responses to growth hormone-releasing factor in the rat. Neuroendocrinology. 53:185-189.
    • (1991) Neuroendocrinology , vol.53 , pp. 185-189
    • Alvarez, C.V.1    Mallo, F.2    Burguera, B.3    Cacicedo, L.4    Dieguez, C.5    Casanueva, F.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.