BRD4 promotes pancreatic ductal adenocarcinoma cell proliferation and enhances gemcitabine resistance

Oncology Reports

Volumn 33, Issue 4, 2015, Pages 1699-1706

  Wang, Yong Hui ^a   Sui, Ya Na ^b   Yan, Kai ^a   Wang, Li Shan ^a   Wang, Fei ^a   Zhou, Jia Hua ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b Weifang Traditional Chinese Hospital   (China)

Author keywords

BRD4; Chemoresistance; Pancreatic cancer; Proliferation; Sonic hedgehog pathway

Indexed keywords

BRD4 PROTEIN; GEMCITABINE; ONCOPROTEIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; BRD4 PROTEIN, HUMAN; DEOXYCYTIDINE; NUCLEAR PROTEIN; SHH PROTEIN, HUMAN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TUMOR PROTEIN;

ADENOCARCINOMA CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER RESISTANCE; CARCINOGENESIS; CELL ASSAY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFICACY; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PANCREATIC DUCTAL ADENOCARCINOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CARCINOMA, PANCREATIC DUCTAL; CELL DIVISION; CELL SURVIVAL; DISEASE COURSE; DRUG EFFECTS; DRUG RESISTANCE; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; NUDE MOUSE; PANCREATIC NEOPLASMS; PATHOLOGY; PHYSIOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR STEM CELL ASSAY;

ANIMALS; APOPTOSIS; CARCINOMA, PANCREATIC DUCTAL; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; DEOXYCYTIDINE; DISEASE PROGRESSION; DRUG RESISTANCE, NEOPLASM; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; MALE; MICE; MICE, NUDE; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PANCREATIC NEOPLASMS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR STEM CELL ASSAY; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84924913767     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.3774     Document Type: Article

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