ABCB2 (TAP1) as the downstream target of SHH signaling enhances pancreatic ductal adenocarcinoma drug resistance

Cancer Letters

Volumn 333, Issue 2, 2013, Pages 152-158

  Xu, Min ^a   Li, Lei ^b   Liu, Zhiqiang ^c   Jiao, Zhijun ^a   Xu, Ping ^a   Kong, Xiangyu ^b   Huang, Haojie ^b   Zhang, Youli ^a  

^a AFFILIATED HOSPITAL OF JIANGSU UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

ABCB2; Drug resistance; Pancreatic cancer; Sonic hedgehog

Indexed keywords

CYCLOPAMINE; GEMCITABINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SONIC HEDGEHOG PROTEIN;

ABCB2 GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER RESISTANCE; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG POTENTIATION; FEMALE; GENE; GENE EXPRESSION; GENE FUNCTION; GENE TARGETING; HUMAN; HUMAN CELL; MOUSE; MULTIGENE FAMILY; NONHUMAN; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; TAP1 GENE; TREATMENT DURATION; TREATMENT RESPONSE; TUMOR VOLUME;

ADENOCARCINOMA; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE, TUMOR; DEOXYCYTIDINE; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; MICE; MICE, NUDE; PANCREATIC NEOPLASMS; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ERINACEIDAE;

EID: 84876706470     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.01.002     Document Type: Article

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