메뉴 건너뛰기




Volumn 4, Issue OCT, 2013, Pages

Targeting peripheral opioid receptors to promote analgesic and anti-inflammatory actions

Author keywords

Analgesia; Anti inammatory; Immune cells; Inammation; Opioids; Pain; Peripheral opioid receptors

Indexed keywords

BETA ENDORPHIN; CD31 ANTIGEN; CHEMOKINE RECEPTOR CXCR2; DELTA OPIATE RECEPTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; KAPPA OPIATE RECEPTOR; LOPERAMIDE; MORPHINE; MU OPIATE RECEPTOR; NALOXONE; NERVE CELL ADHESION MOLECULE; NEUROPEPTIDE; OPIATE AGONIST; OPIATE RECEPTOR;

EID: 84924911902     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2013.00132     Document Type: Article
Times cited : (81)

References (70)
  • 1
    • 61449115836 scopus 로고    scopus 로고
    • Surprising up-regulation of P-selectin glycopro-tein ligand-1 (PSGL-1) in endotoxin-induced uveitis
    • Almulki, L., Noda, K., Amini, R., Schering, A., Garland, R. C., Nakao, S., et al. (2009). Surprising up-regulation of P-selectin glycopro-tein ligand-1 (PSGL-1) in endotoxin-induced uveitis. FASEB J. 23, 929-39. doi: 10.1096/fj.08-118760
    • (2009) FASEB J , vol.23 , pp. 929-939
    • Almulki, L.1    Noda, K.2    Amini, R.3    Schering, A.4    Garland, R.C.5    Nakao, S.6
  • 2
    • 3142708596 scopus 로고    scopus 로고
    • Sympathetic acti-vation triggers endogenous opioid release and analgesia within periph-eral inamed tissue
    • Binder, W., Mousa, S. A., Sitte, N., Kaiser, M., Stein, C., and Schafer, M. (2004). Sympathetic acti-vation triggers endogenous opioid release and analgesia within periph-eral inamed tissue. Eur. J. Neurosci. 20, 92-100. doi: 10.1111/j.1460-9568. 2004.03459.x
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 92-100
    • Binder, W.1    Mousa, S.A.2    Sitte, N.3    Kaiser, M.4    Stein, C.5    Schafer, M.6
  • 3
    • 3042593938 scopus 로고    scopus 로고
    • Tissue monocytes/macrophages in inam-mation: hyperalgesia versus opioid-mediated peripheral antinociception
    • Brack, A., Labuz, D., Schiltz, A., Rittner, H. L., Machelska, H., Schafer, M., et al. (2004a). Tissue monocytes/macrophages in inam-mation: hyperalgesia versus opioid-mediated peripheral antinociception. Anesthesiology 101, 204-11. doi: 10.1097/00000542-200407000-00031
    • (2004) Anesthesiology , vol.101 , pp. 204-211
    • Brack, A.1    Labuz, D.2    Schiltz, A.3    Rittner, H.L.4    Machelska, H.5    Schafer, M.6
  • 4
    • 0347993738 scopus 로고    scopus 로고
    • Mobilization of opioid-containing polymorphonu-clear cells by hematopoietic growth factors and inuence on inamma-tory pain
    • Brack, A., Rittner, H. L., Machelska, H., Beschmann, K., Sitte, N., Schafer, M., et al. (2004b). Mobilization of opioid-containing polymorphonu-clear cells by hematopoietic growth factors and inuence on inamma-tory pain. Anesthesiology 100, 14-57. doi: 10.1097/00000542-200401000-00024
    • (2004) Anesthesiology , vol.100 , pp. 14-57
    • Brack, A.1    Rittner, H.L.2    Machelska, H.3    Beschmann, K.4    Sitte, N.5    Schafer, M.6
  • 5
    • 9244241517 scopus 로고    scopus 로고
    • Control of inammatory pain by chemokine-mediated recruitment of opioid-containing polymorphonu-clear cells
    • Brack, A., Rittner, H. L., Machel-ska, H., Leder, K., Mousa, S. A., Schafer, M., et al. (2004c). Control of inammatory pain by chemokine-mediated recruitment of opioid-containing polymorphonu-clear cells. Pain 112, 229-38. doi: 10.1016/j.pain.2004.08.029
    • (2004) Pain , vol.112 , pp. 229-238
    • Brack, A.1    Rittner, H.L.2    Machel-ska, H.3    Leder, K.4    Mousa, S.A.5    Schafer, M.6
  • 6
    • 1342279408 scopus 로고    scopus 로고
    • Endoge-nous peripheral antinociception in early inammation is not limited by the number of opioid-containing leukocytes but by opioid receptor expression
    • Brack, A., Rittner, H. L., Machel-ska, H., Shaqura, M., Mousa, S. A., Labuz, D., et al. (2004d). Endoge-nous peripheral antinociception in early inammation is not limited by the number of opioid-containing leukocytes but by opioid receptor expression. Pain 108, 67-75. doi: 10.1016/j.pain.2003.12.008
    • (2004) Pain , vol.108 , pp. 67-75
    • Brack, A.1    Rittner, H.L.2    Machel-ska, H.3    Shaqura, M.4    Mousa, S.A.5    Labuz, D.6
  • 7
    • 77953619984 scopus 로고    scopus 로고
    • Opioid receptors and opioid peptide-producing leuko-cytes in inammatory pain - basic and therapeutic aspects
    • Busch-Dienstfertig, M., and Stein, C. (2010). Opioid receptors and opioid peptide-producing leuko-cytes in inammatory pain - basic and therapeutic aspects. Brain Behav. Immun. 24, 683-694. doi: 10.1016/j.bbi.2009.10.013
    • (2010) Brain Behav. Immun. , vol.24 , pp. 683-694
    • Busch-Dienstfertig, M.1    Stein, C.2
  • 8
    • 0035127196 scopus 로고    scopus 로고
    • Immune-derived opioids and peripheral antinocicep-tion
    • Cabot, P. J. (2001). Immune-derived opioids and peripheral antinocicep-tion. Clin. Exp. Pharmacol. Physiol. 28, 230-232. doi: 10.1046/j.1440-1681.2001.03425.x
    • (2001) Clin. Exp. Pharmacol. Physiol. , vol.28 , pp. 230-232
    • Cabot, P.J.1
  • 9
    • 0030814120 scopus 로고    scopus 로고
    • Immune cell-derived beta-endorphin. Production, release, and control of inammatory pain in rats
    • Cabot, P. J., Carter, L., Gaiddon, C., Zhang, Q., Schafer, M., Loefer, J. P., et al. (1997). Immune cell-derived beta-endorphin. Production, release, and control of inammatory pain in rats. J. Clin. Invest. 100, 142-148. doi: 10.1172/JCI119506
    • (1997) J. Clin. Invest. , vol.100 , pp. 142-148
    • Cabot, P.J.1    Carter, L.2    Gaiddon, C.3    Zhang, Q.4    Schafer, M.5    Loefer, J.P.6
  • 10
    • 0037174639 scopus 로고    scopus 로고
    • Neural and immunological synaptic relations
    • Dustin, M. L., and Colman, D. R. (2002). Neural and immunological synaptic relations. Science 298, 785-789. doi: 10.1126/science.1076386
    • (2002) Science , vol.298 , pp. 785-789
    • Dustin, M.L.1    Colman, D.R.2
  • 11
    • 70350719371 scopus 로고    scopus 로고
    • TNF-alpha as a therapeutic target in inammatory diseases, ischemia-reperfusion injury and trauma
    • Esposito, E., and Cuzzocrea, S. (2009). TNF-alpha as a therapeutic target in inammatory diseases, ischemia-reperfusion injury and trauma. Curr. Med. Chem. 16, 3152-3167. doi: 10.2174/092986709788803024
    • (2009) Curr. Med. Chem. , vol.16 , pp. 3152-3167
    • Esposito, E.1    Cuzzocrea, S.2
  • 12
    • 33845192455 scopus 로고    scopus 로고
    • Effects of carrageenan and mor-phine on acute inammation and pain in Lewis and Fischer rats
    • Fecho, K., Manning, E. L., Maixner, W., and Schmitt, C. P. (2007). Effects of carrageenan and mor-phine on acute inammation and pain in Lewis and Fischer rats. Brain Behav. Immun. 21, 68-78. doi: 10.1016/j.bbi.2006.02.003
    • (2007) Brain Behav. Immun. , vol.21 , pp. 68-78
    • Fecho, K.1    Manning, E.L.2    Maixner, W.3    Schmitt, C.P.4
  • 14
  • 15
    • 34249720051 scopus 로고    scopus 로고
    • Inu-ence of pain treatment by epidu-ral fentanyl and bupivacaine on homing of opioid-containing leuko-cytes to surgical wounds
    • Heurich, M., Mousa, S. A., Lenzner, M., Morciniec, P., Kopf, A., Welte, M., et al. (2007). Inu-ence of pain treatment by epidu-ral fentanyl and bupivacaine on homing of opioid-containing leuko-cytes to surgical wounds. Brain Behav. Immun. 21, 544-552. doi: 10.1016/j.bbi.2006.10.014
    • (2007) Brain Behav. Immun. , vol.21 , pp. 544-552
    • Heurich, M.1    Mousa, S.A.2    Lenzner, M.3    Morciniec, P.4    Kopf, A.5    Welte, M.6
  • 16
    • 77956189271 scopus 로고    scopus 로고
    • Mech-anisms of peripheral immune-cell-mediated analgesia in inammation: clinical and therapeutic implications
    • Hua, S., and Cabot, P. J. (2010). Mech-anisms of peripheral immune-cell-mediated analgesia in inammation: clinical and therapeutic implications. Trends Pharmacol. Sci. 31, 427-433. doi: 10.1016/j.tips.2010.05.008
    • (2010) Trends Pharmacol. Sci. , vol.31 , pp. 427-433
    • Hua, S.1    Cabot, P.J.2
  • 17
    • 84878232350 scopus 로고    scopus 로고
    • Targeted nanoparticles that mimic immune cells in pain control inducing anal-gesic and anti-inammatory actions: a potential novel treatment of acute and chronic pain condition
    • Hua, S., andCabot, P. J. (2013). Targeted nanoparticles that mimic immune cells in pain control inducing anal-gesic and anti-inammatory actions: a potential novel treatment of acute and chronic pain condition. Pain Physician 16, E199-E216.
    • (2013) Pain Physician , vol.16 , pp. E199-E216
    • Hua, S.1    Cabot, P.J.2
  • 18
    • 33845630746 scopus 로고    scopus 로고
    • The neural cell adhe-sion molecule antibody blocks cold water swim stress-induced analge-sia and cell adhesion between lym-phocytes and cultured dorsal root ganglion neurons
    • Hua, S., Hermanussen, S., Tang, L., Monteith, G. R., and Cabot, P. J. (2006). The neural cell adhe-sion molecule antibody blocks cold water swim stress-induced analge-sia and cell adhesion between lym-phocytes and cultured dorsal root ganglion neurons. Anesth. Analg. 103, 1558-1564. doi: 10.1213/01. ane.0000243410.61451.c1
    • (2006) Anesth. Analg. , vol.103 , pp. 1558-1564
    • Hua, S.1    Hermanussen, S.2    Tang, L.3    Monteith, G.R.4    Cabot, P.J.5
  • 19
    • 0028980313 scopus 로고
    • Interleukin-1 beta induces long-term increase of axonally trans-ported opiate receptors and sub-stance P
    • Jeanjean, A. P., Moussaoui, S. M., Mal-oteaux, J. M., and Laduron, P. M. (1995). Interleukin-1 beta induces long-term increase of axonally trans-ported opiate receptors and sub-stance P. Neuroscience 68, 151-157. doi: 10.1016/0306-4522(95)00106-S
    • (1995) Neuroscience , vol.68 , pp. 151-157
    • Jeanjean, A.P.1    Moussaoui, S.M.2    Mal-oteaux, J.M.3    Laduron, P.M.4
  • 20
    • 20444482444 scopus 로고    scopus 로고
    • Positive feedback loop of interleukin-1beta upregulating production of inammatory mediators in human intervertebral disc cells in vitro
    • Jimbo, K., Park, J. S., Yokosuka, K., Sato, K., and Nagata, K. (2005). Positive feedback loop of interleukin-1beta upregulating production of inammatory mediators in human intervertebral disc cells in vitro. J. Neurosurg. Spine 2, 589-595. doi: 10.3171/spi.2005.2.5.0589
    • (2005) J. Neurosurg. Spine. , vol.2 , pp. 589-595
    • Jimbo, K.1    Park, J.S.2    Yokosuka, K.3    Sato, K.4    Nagata, K.5
  • 21
    • 77957875318 scopus 로고    scopus 로고
    • Mu and delta opi-oid receptors on nociceptors atten-uate mechanical hyperalgesia in rat
    • Joseph, E. K., and Levine, J. D. (2010). Mu and delta opi-oid receptors on nociceptors atten-uate mechanical hyperalgesia in rat. Neuroscience 171, 344-350. doi: 10.1016/j.neuroscience.2010.08.035
    • (2010) Neuroscience , vol.171 , pp. 344-350
    • Joseph, E.K.1    Levine, J.D.2
  • 22
    • 77950657123 scopus 로고    scopus 로고
    • Shared mech-anisms for opioid tolerance and a transition to chronic pain
    • 4660-4066
    • Joseph, E. K., Reichling, D. B., and Levine, J. D. (2010). Shared mech-anisms for opioid tolerance and a transition to chronic pain. J. Neu-rosci. 30, 4660-4066. doi: 10.1523/JNEUROSCI.5530-09.2010
    • (2010) J. Neu-rosci. , vol.30
    • Joseph, E.K.1    Reichling, D.B.2    Levine, J.D.3
  • 23
    • 11244344642 scopus 로고    scopus 로고
    • Receptor endocytosis counteracts the develop-ment of opioid tolerance
    • Koch, T., Widera, A., Bartzsch, K., Schulz, S., Brandenburg, L. O., Wun-drack, N., et al. (2005). Receptor endocytosis counteracts the develop-ment of opioid tolerance. Mol. Phar-macol. 67, 280-287. doi: 10.1124/mol.104.004994
    • (2005) Mol. Phar-macol. , vol.67 , pp. 280-287
    • Koch, T.1    Widera, A.2    Bartzsch, K.3    Schulz, S.4    Brandenburg, L.O.5    Wun-drack, N.6
  • 24
    • 0036037475 scopus 로고    scopus 로고
    • Endothelial cells at inammatory sites as target for therapeutic intervention
    • Koning, G. A., Schiffelers, R. M., and Storm, G. (2002). Endothelial cells at inammatory sites as target for therapeutic intervention. Endothe-lium 9, 161-171. doi: 10.1080/10623320213631
    • (2002) Endothe-lium , vol.9 , pp. 161-171
    • Koning, G.A.1    Schiffelers, R.M.2    Storm, G.3
  • 26
    • 33646438844 scopus 로고    scopus 로고
    • Peripheral antinociceptive effects of exogenous and immune cell-derived endomor-phins in prolonged inammatory pain
    • Labuz, D., Berger, S., Mousa, S. A., Zollner, C., Rittner, H. L., Shaqura, M. A., et al. (2006). Peripheral antinociceptive effects of exogenous and immune cell-derived endomor-phins in prolonged inammatory pain. J. Neurosci. 26, 4350-4358. doi: 10.1523/JNEUROSCI.4349-05.2006
    • (2006) J. Neurosci. , vol.26 , pp. 4350-4358
    • Labuz, D.1    Berger, S.2    Mousa, S.A.3    Zollner, C.4    Rittner, H.L.5    Shaqura, M.A.6
  • 27
    • 34447335107 scopus 로고    scopus 로고
    • Relative contribution of peripheral versus central opioid receptors to antinociception
    • Labuz, D., Mousa, S. A., Schafer, M., Stein, C., and Machelska, H. (2007). Relative contribution of peripheral versus central opioid receptors to antinociception. Brain Res. 1160, 30-38. doi: 10.1016/j. brainres.2007.05.049
    • (2007) Brain Res , vol.1160 , pp. 30-38
    • Labuz, D.1    Mousa, S.A.2    Schafer, M.3    Stein, C.4    Machelska, H.5
  • 29
    • 77956187124 scopus 로고    scopus 로고
    • lymphocytes containing beta-endorphin emeliorate mechan-ical hypersensitivity following nerve injury
    • Labuz, D., Schreiter, A., Schmidt, Y., Brack, A., and Machelska, H. T. (2010). lymphocytes containing beta-endorphin emeliorate mechan-ical hypersensitivity following nerve injury. Brain Behav. Immun. 24, 1045-1053. doi: 10.1016/j. bbi.2010.04.001
    • (2010) Brain Behav. Immun. , vol.24 , pp. 1045-1053
    • Labuz, D.1    Schreiter, A.2    Schmidt, Y.3    Brack, A.4    Machelska, H.T.5
  • 31
    • 0034128416 scopus 로고    scopus 로고
    • Molecular mechanisms and regulation of opioid receptor signaling
    • Law, P. Y., Wong, Y. H., and Loh, H. H. (2000). Molecular mechanisms and regulation of opioid receptor signaling. Annu. Rev. Pharmacol. Toxi col. 40, 389-430. doi: 10.1146/annurev.pharmtox.40.1.389
    • (2000) Annu. Rev. Pharmacol. Toxi col. , vol.40 , pp. 389-430
    • Law, P.Y.1    Wong, Y.H.2    Loh, H.H.3
  • 32
    • 30044447736 scopus 로고    scopus 로고
    • Immune cell migration in inammation: present and future therapeutic targets
    • Luster, A. D., Alon, R., and von Andrian, U. H. (2005). Immune cell migration in inammation: present and future therapeutic targets. Nat. Immunol. 6, 1182-1190. doi: 10.1038/ni1275
    • (2005) Nat. Immunol. , vol.6 , pp. 1182-1190
    • Luster, A.D.1    Alon, R.2    von Andrian, U.H.3
  • 33
    • 3242744314 scopus 로고    scopus 로고
    • Selectins and inte-grins but not platelet-endothelial cell adhesion molecule-1 regulate opioid inhibition of inammatory pain
    • Machelska, H., Brack, A., Mousa, S. A., Schopohl, J.K., Rittner, H. L., Schafer, M., et al. (2004). Selectins and inte-grins but not platelet-endothelial cell adhesion molecule-1 regulate opioid inhibition of inammatory pain. Br. J. Pharmacol. 142, 772-780. doi: 10.1038/sj.bjp.0705837
    • (2004) Br. J. Pharmacol. , vol.142 , pp. 772-780
    • Machelska, H.1    Brack, A.2    Mousa, S.A.3    Schopohl, J.K.4    Rittner, H.L.5    Schafer, M.6
  • 34
    • 0031757354 scopus 로고    scopus 로고
    • Pain control in inammation governed by selectins
    • Machelska, H., Cabot, P. J., Mousa, S.A., Zhang, Q., and Stein, C. (1998). Pain control in inammation governed by selectins. Nat. Med. 4, 1425-1428. doi: 10.1038/4017
    • (1998) Nat. Med. , vol.4 , pp. 1425-1428
    • Machelska, H.1    Cabot, P.J.2    Mousa, S.A.3    Zhang, Q.4    Stein, C.5
  • 35
    • 0036662907 scopus 로고    scopus 로고
    • Opioid con-trol of inammatory pain regulated by intercellular adhesion molecule-1
    • Machelska, H., Mousa, S. A., Brack, A., Schopohl, J. K., Rittner, H. L., Schafer, M., et al. (2002). Opioid con-trol of inammatory pain regulated by intercellular adhesion molecule-1. J. Neurosci. 22, 5588-5596.
    • (2002) J. Neurosci. , vol.22 , pp. 5588-5596
    • Machelska, H.1    Mousa, S.A.2    Brack, A.3    Schopohl, J.K.4    Rittner, H.L.5    Schafer, M.6
  • 36
    • 0142043848 scopus 로고    scopus 로고
    • Different mech-anisms of intrinsic pain inhibition in early and late inammation
    • Machelska, H., Schopohl, J. K., Mousa, S. A., Labuz, D., Schafer. M., and Stein, C. (2003). Different mech-anisms of intrinsic pain inhibition in early and late inammation. J. Neuroimmunol. 141, 30-39. doi: 10.1016/S0165-5728(03)00213-3
    • (2003) J. Neuroimmunol. , vol.141 , pp. 30-39
    • Machelska, H.1    Schopohl, J.K.2    Mousa, S.A.3    Labuz, D.4    Schafer, M.5    Stein, C.6
  • 37
    • 0034255712 scopus 로고    scopus 로고
    • Co-expression of beta-endorphin with adhesion molecules in a model of inammatory pain
    • Mousa, S. A., Machelska, H., Schafer, M., and Stein, C. (2000). Co-expression of beta-endorphin with adhesion molecules in a model of inammatory pain. J. Neu-roimmunol. 108, 160-170. doi: 10.1016/S0165-5728(00)00284-8
    • (2000) J. Neu-roimmunol. , vol.108 , pp. 160-170
    • Mousa, S.A.1    Machelska, H.2    Schafer, M.3    Stein, C.4
  • 38
    • 0035795077 scopus 로고    scopus 로고
    • beta-Endorphin-containing memory-cells and mu-opioid receptors undergo transport to peripheral inamed tis-sue
    • Mousa, S. A., Zhang, Q., Sitte, N., Ji, R., and Stein, C. (2001). beta-Endorphin-containing memory-cells and mu-opioid receptors undergo transport to peripheral inamed tis-sue. J. Neuroimmunol. 115, 71-78. doi: 10.1016/S0165-5728(01) 00271-5
    • (2001) J. Neuroimmunol. , vol.115 , pp. 71-78
    • Mousa, S.A.1    Zhang, Q.2    Sitte, N.3    Ji, R.4    Stein, C.5
  • 39
    • 21044455501 scopus 로고    scopus 로고
    • Targeting of antioxidant and anti-thrombotic drugs to endothe-lial cell adhesion molecules
    • Muro, S., and Muzykantov, V. R. (2005). Targeting of antioxidant and anti-thrombotic drugs to endothe-lial cell adhesion molecules. Curr. Pharm. Des. 11, 2383-2401. doi: 10.2174/1381612054367274
    • (2005) Curr. Pharm. Des. , vol.11 , pp. 2383-2401
    • Muro, S.1    Muzykantov, V.R.2
  • 40
    • 0036166872 scopus 로고    scopus 로고
    • Up-regulation of L-selectin and E-selectin in hypersensitivity pneu-monitis
    • Navarro, C., Mendoza, F., Bar-rera, L., Segura-Valdez, L., Gaxi-ola, M., Paramo, I., et al. (2002). Up-regulation of L-selectin and E-selectin in hypersensitivity pneu-monitis. Chest 121, 354-360. doi: 10.1378/chest.121.2.354
    • (2002) Chest , vol.121 , pp. 354-360
    • Navarro, C.1    Mendoza, F.2    Bar-rera, L.3    Segura-Valdez, L.4    Gaxi-ola, M.5    Paramo, I.6
  • 41
    • 57249084771 scopus 로고    scopus 로고
    • Potential utility of peripherally applied lop-eramide in oral chronic graft-versus-host disease related pain
    • Nozaki-Taguchi, N., Shutoh, M., and Shimoyama, N. (2008). Potential utility of peripherally applied lop-eramide in oral chronic graft-versus-host disease related pain. Jpn. J. Clin. Oncol. 38, 857-60. doi: 10.1093/jjco/hyn110
    • (2008) Jpn. J. Clin. Oncol. , vol.38 , pp. 857-860
    • Nozaki-Taguchi, N.1    Shutoh, M.2    Shimoyama, N.3
  • 42
    • 0032622187 scopus 로고    scopus 로고
    • Characterization of the antihyperalgesic action of a novel peripheral mu-opioid receptor ago-nist - loperamide
    • Nozaki-Taguchi, N., and Yaksh, T. L. (1999). Characterization of the antihyperalgesic action of a novel peripheral mu-opioid receptor ago-nist - loperamide. Anesthesiology 90, 225-234. doi: 10.1097/00000542-199901000-00029
    • (1999) Anesthesiology , vol.90 , pp. 225-234
    • Nozaki-Taguchi, N.1    Yaksh, T.L.2
  • 44
    • 0037651166 scopus 로고    scopus 로고
    • Anti-inammatory properties of the mu opioid receptor support its use in the treatment of colon inammation
    • Philippe, D., Dubuquoy, L., Groux, H., Brun, V., Chuoi-Mariot, M. T., Gaveriaux-Ruff, C., et al. (2003). Anti-inammatory properties of the mu opioid receptor support its use in the treatment of colon inammation. J. Clin. Invest. 111, 1329-1338.
    • (2003) J. Clin. Invest. , vol.111 , pp. 1329-1338
    • Philippe, D.1    Dubuquoy, L.2    Groux, H.3    Brun, V.4    Chuoi-Mariot, M.T.5    Gaveriaux-Ruff, C.6
  • 45
    • 0026520443 scopus 로고
    • Gene expression and local-ization of opioid peptides in immune cells of inamed tissue: functional role in antinociception
    • Przewlocki, R., Hassan, A. H., Lason, W., Epplen, C., Herz, A., and Stein, C. (1992). Gene expression and local-ization of opioid peptides in immune cells of inamed tissue: functional role in antinociception. Neuroscience 48, 491-500. doi: 10.1016/0306-4522(92)90509-Z
    • (1992) Neuroscience , vol.48 , pp. 491-500
    • Przewlocki, R.1    Hassan, A.H.2    Lason, W.3    Epplen, C.4    Herz, A.5    Stein, C.6
  • 46
    • 6344291677 scopus 로고    scopus 로고
    • Rapid upregulation of mu opioid recep-tor mRNA in dorsal root ganglia in response to peripheral inamma-tion depends on neuronal conduc-tion
    • Puehler, W., Zollner, C., Brack, A., Shaqura, M. A., Krause, H., Schafer, M., et al. (2004). Rapid upregulation of mu opioid recep-tor mRNA in dorsal root ganglia in response to peripheral inamma-tion depends on neuronal conduc-tion. Neuroscience 129, 473-479. doi: 10.1016/j.neuroscience.2004.06.086
    • (2004) Neuroscience , vol.129 , pp. 473-479
    • Puehler, W.1    Zollner, C.2    Brack, A.3    Shaqura, M.A.4    Krause, H.5    Schafer, M.6
  • 47
    • 0034900301 scopus 로고    scopus 로고
    • Opioid peptide-expressing leukocytes: iden-tication, recruitment, and simul-taneously increasing inhibition of inammatory pain
    • Rittner, H. L., Brack, A., Machel-ska, H., Mousa, S. A., Bauer, M., Schafer, M., et al. (2001). Opioid peptide-expressing leukocytes: iden-tication, recruitment, and simul-taneously increasing inhibition of inammatory pain. Anesthesiology 95, 500-508. doi: 10.1097/00000542-200108000-00036
    • (2001) Anesthesiology , vol.95 , pp. 500-508
    • Rittner, H.L.1    Brack, A.2    Machel-ska, H.3    Mousa, S.A.4    Bauer, M.5    Schafer, M.6
  • 48
    • 33845601602 scopus 로고    scopus 로고
    • Pain control by CXCR2 ligands through Ca2+-regulated release of opioid peptides from polymorphonuclear cells
    • Rittner, H. L., Labuz, D., Schae-fer, M., Mousa, S. A., Schulz, S., Schafer, M., et al. (2006). Pain control by CXCR2 ligands through Ca2+-regulated release of opioid peptides from polymorphonuclear cells. FASEB J. 20, 2627-2629. doi: 10.1096/fj.06-6077fje
    • (2006) FASEB J , vol.20 , pp. 2627-2629
    • Rittner, H.L.1    Labuz, D.2    Schae-fer, M.3    Mousa, S.A.4    Schulz, S.5    Schafer, M.6
  • 49
    • 28844490637 scopus 로고    scopus 로고
    • Leukocytes in the regulation of pain and analgesia
    • Rittner, H. L., Machelska, H., and Stein, C. (2005). Leukocytes in the regulation of pain and analgesia. J. Leukoc. Biol. 78, 1215-1222. doi: 10.1189/jlb.0405223
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 1215-1222
    • Rittner, H.L.1    Machelska, H.2    Stein, C.3
  • 50
    • 14644430995 scopus 로고    scopus 로고
    • Involvement of cytokines, chemokines and adhesion molecules in opioid analgesia
    • Rittner, H. L., and Stein, C. (2005). Involvement of cytokines, chemokines and adhesion molecules in opioid analgesia. Eur. J. Pain 9, 109-112. doi: 10.1016/j.ejpain.2004.05.009
    • (2005) Eur. J. Pain. , vol.9 , pp. 109-112
    • Rittner, H.L.1    Stein, C.2
  • 51
    • 0038410263 scopus 로고    scopus 로고
    • Cytokines and peripheral analgesia
    • Schafer, M. (2003). Cytokines and peripheral analgesia. Adv. Exp. Med. Biol. 521, 40-50.
    • (2003) Adv. Exp. Med. Biol. , vol.521 , pp. 40-50
    • Schafer, M.1
  • 52
    • 0343145704 scopus 로고    scopus 로고
    • Corticotropin-releasing fac-tor in antinociception and inam-mation
    • Schafer, M., Mousa, S. A., and Stein, C. (1997). Corticotropin-releasing fac-tor in antinociception and inam-mation. Eur. J. Pharmacol. 323, 1-10. doi: 10.1016/S0014-2999(97) 00057-5
    • (1997) Eur. J. Pharmacol. , vol.323 , pp. 1-10
    • Schafer, M.1    Mousa, S.A.2    Stein, C.3
  • 54
    • 0037221306 scopus 로고    scopus 로고
    • Mod-ulation of peripheral endogenous opioid analgesia by central afferent blockade
    • Schmitt, T. K., Mousa, S. A., Brack, A., Schmidt, D. K., Rittner, H. L., Welte, M., et al. (2003). Mod-ulation of peripheral endogenous opioid analgesia by central afferent blockade. Anesthesiology 98, 195-202. doi: 10.1097/00000542-200301000-00030
    • (2003) Anesthesiology , vol.98 , pp. 195-202
    • Schmitt, T.K.1    Mousa, S.A.2    Brack, A.3    Schmidt, D.K.4    Rittner, H.L.5    Welte, M.6
  • 55
    • 84870341507 scopus 로고    scopus 로고
    • Machel-ska H. Pain inhibition by blocking leukocytic and neuronal opioid pep-tidases in peripheral inamed tis-sue
    • Schreiter, A., Gore, C., Labuz, D., Fournie-Zaluski, M. C., Roques, B. P., Stein, C., et al. (2012). Machel-ska H. Pain inhibition by blocking leukocytic and neuronal opioid pep-tidases in peripheral inamed tis-sue. FASEB J. 26, 5161-5171. doi: 10.1096/fj.12-208678
    • (2012) FASEB J , vol.26 , pp. 5161-5171
    • Schreiter, A.1    Gore, C.2    Labuz, D.3    Fournie-Zaluski, M.C.4    Roques, B.P.5    Stein, C.6
  • 56
    • 0028934555 scopus 로고
    • Increased expression of cell adhesion molecule P-selectin in active inammatory bowel disease
    • Schurmann, G. M., Bishop, A. E., Facer, P., Vecchio, M., Lee, J. C., Ramp-ton, D. S., et al. (1995). Increased expression of cell adhesion molecule P-selectin in active inammatory bowel disease. Gut 36, 411-418. doi: 10.1136/gut.36.3.411
    • (1995) Gut , vol.36 , pp. 411-418
    • Schurmann, G.M.1    Bishop, A.E.2    Facer, P.3    Vecchio, M.4    Lee, J.C.5    Ramp-ton, D.S.6
  • 57
    • 0032752320 scopus 로고    scopus 로고
    • Intraarticular morphine versus dex-amethasone in chronic arthritis
    • Stein, A., Yassouridis, A., Szopko, C., Helmke, K., and Stein, C. (1999). Intraarticular morphine versus dex-amethasone in chronic arthritis. Pain 83, 525-532. doi: 10.1016/S0304-3959(99)00156-6
    • (1999) Pain , vol.83 , pp. 525-532
    • Stein, A.1    Yassouridis, A.2    Szopko, C.3    Helmke, K.4    Stein, C.5
  • 58
    • 84892575256 scopus 로고    scopus 로고
    • Opioids, sensory systems and chronic pain
    • Stein, C. (2013). Opioids, sensory systems and chronic pain. Eur. J. Pharmacol. 716, 179-187. doi: 10.1016/j.ejphar.2013.01.076
    • (2013) Eur. J. Pharmacol. , vol.716 , pp. 179-187
    • Stein, C.1
  • 59
    • 59349088060 scopus 로고    scopus 로고
    • Peripheral mechanisms of opioid analgesia
    • Stein, C., and Lang, L. J. (2009). Peripheral mechanisms of opioid analgesia. Curr. Opin. Pharmacol. 9, 3-8. doi: 10.1016/j.coph.2008.12. 009
    • (2009) Curr. Opin. Pharmacol. , vol.9 , pp. 3-8
    • Stein, C.1    Lang, L.J.2
  • 60
    • 0027165525 scopus 로고
    • Local analgesic effect of endogenous opioid peptides
    • Stein, C., Hassan, A. H., Lehrberger, K., Gieng, J., and Yassouridis, A. (1993). Local analgesic effect of endogenous opioid peptides. Lancet 342, 321-324. doi: 10.1016/0140-6736(93)91471-W
    • (1993) Lancet , vol.342 , pp. 321-324
    • Stein, C.1    Hassan, A.H.2    Lehrberger, K.3    Gieng, J.4    Yassouridis, A.5
  • 61
    • 80053606300 scopus 로고    scopus 로고
    • Modulation of peripheral sensory neurons by the immune system: implications for pain therapy
    • Stein, C., and Machelska, H. (2011). Modulation of peripheral sensory neurons by the immune system: implications for pain therapy. Phar-macol. Rev. 63, 860-881. doi: 10.1124/pr.110.003145
    • (2011) Phar-macol. Rev. , vol.63 , pp. 860-881
    • Stein, C.1    Machelska, H.2
  • 62
    • 0041965945 scopus 로고    scopus 로고
    • Attacking pain at its source: new perspectives on opi-oids
    • Stein, C., Schafer, M., and Machel-ska, H. (2003). Attacking pain at its source: new perspectives on opi-oids. Nat. Med. 9, 1003-1008. doi: 10.1038/nm908
    • (2003) Nat. Med. , vol.9 , pp. 1003-1008
    • Stein, C.1    Schafer, M.2    Machel-ska, H.3
  • 63
    • 67650066615 scopus 로고    scopus 로고
    • Selective upregulation of endothelial E-selectin in response to Helicobacter pylori-induced gastritis
    • 3109-3016
    • Svensson, H., Hansson, M., Kilhamn, J., Backert, S., and Quiding-Jarbrink, M. (2009). Selective upregulation of endothelial E-selectin in response to Helicobacter pylori-induced gastritis. Infect. Immun. 77, 3109-3016. doi: 10.1128/IAI.01460-08
    • (2009) Infect. Immun. , vol.77
    • Svensson, H.1    Hansson, M.2    Kilhamn, J.3    Backert, S.4    Quiding-Jarbrink, M.5
  • 64
    • 39549118699 scopus 로고    scopus 로고
    • Topi-cal opioids for painful ulcers in systemic sclerosis
    • van Ingen, I. L., Jansen, M. M., and Barrera, P. (2010). Topi-cal opioids for painful ulcers in systemic sclerosis. Ann. Rheum. Dis. 67. doi: 10.1136/ard.2007.076 224
    • (2010) Ann. Rheum. Dis. , pp. 67
    • van Ingen, I.L.1    Jansen, M.M.2    Barrera, P.3
  • 65
    • 33745247790 scopus 로고    scopus 로고
    • The effects of pH on beta-endorphin and morphine inhibition of calcium transients in dorsal root ganglion neurons
    • Vetter, I., Kapitzke, D., Hermanussen, S., Monteith, G. R., and Cabot, P. J. (2006). The effects of pH on beta-endorphin and morphine inhibition of calcium transients in dorsal root ganglion neurons. J. Pain 7, 488-499. doi: 10.1016/j.jpain.2006.01. 456
    • (2006) J. Pain. , vol.7 , pp. 488-499
    • Vetter, I.1    Kapitzke, D.2    Hermanussen, S.3    Monteith, G.R.4    Cabot, P.J.5
  • 66
    • 0038414661 scopus 로고    scopus 로고
    • Anti-inammatory effects of opioids
    • Walker, J. S. (2003). Anti-inammatory effects of opioids. Adv. Exp. Med. Biol. 521, 148-160.
    • (2003) Adv. Exp. Med. Biol. , vol.521 , pp. 148-160
    • Walker, J.S.1
  • 67
    • 77955606622 scopus 로고    scopus 로고
    • Coexpression of delta- and mu-opioid receptors in nociceptive sensory neurons
    • Wang, H. B., Zhao, B., Zhong, Y. Q., Li, K. C., Li, Z. Y., Wang, Q., et al. (2010). Coexpression of delta- and mu-opioid receptors in nociceptive sensory neurons. Proc. Natl. Acad. Sci. U.S.A. 107, 13117-13122. doi: 10.1073/pnas.1008382107
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 13117-13122
    • Wang, H.B.1    Zhao, B.2    Zhong, Y.Q.3    Li, K.C.4    Li, Z.Y.5    Wang, Q.6
  • 68
    • 34249901056 scopus 로고    scopus 로고
    • A randomised controlled trial to test the anal-gesic efcacy of topical morphine on minor supercial and partial thick-ness burns in accident and emergency departments
    • Welling, A. (2007). A randomised controlled trial to test the anal-gesic efcacy of topical morphine on minor supercial and partial thick-ness burns in accident and emergency departments. Emerg. Med. J. 24. 408-412. doi: 10.1136/emj.2007.047324
    • (2007) Emerg. Med. J. , pp. 408-412
    • Welling, A.1
  • 70
    • 40549105390 scopus 로고    scopus 로고
    • Chronic morphine use does not induce peripheral tolerance in a rat model of inammatory pain
    • Zollner, C., Mousa, S. A., Fischer, O., Rittner, H. L., Shaqura, M., Brack, A., et al. (2008). Chronic morphine use does not induce peripheral tolerance in a rat model of inammatory pain. J. Clin. Invest. 118, 1065-1073. doi: 10.1172/JCI25911
    • (2008) J. Clin. Invest. , vol.118 , pp. 1065-1073
    • Zollner, C.1    Mousa, S.A.2    Fischer, O.3    Rittner, H.L.4    Shaqura, M.5    Brack, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.